Interactions between insulin and exercise

Indoxyl sulfate impairs angiogenesis via chronic aryl hydrocarbon receptor activation

(2021) Zachary R. Salyers et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Deep muscle-proteomic analysis of freeze-dried human muscle biopsies reveals fiber type-specific adaptations to exercise training

(2021) A. S. Deshmukh et al.   Nature Communications

Excessive exercise training causes mitochondrial functional impairment and decreases glucose tolerance in healthy volunteers

(2021) Mikael Flockhart et al.   Cell Metabolism

The many actions of insulin in skeletal muscle, the paramount tissue determining glycemia

(2021) Lykke Sylow et al.   Cell Metabolism

β‐Catenin is required for optimal exercise‐ and contraction‐stimulated skeletal muscle glucose uptake

(2021) Stewart W. C. Masson et al.   JOURNAL OF PHYSIOLOGY-LONDON

The wonder exerkines—novel insights: a critical state-of-the-art review

(2021) Laura Magliulo et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Impact of aging and exercise on skeletal muscle mitochondrial capacity, energy metabolism, and physical function

(2021) L. Grevendonk et al.   Nature Communications

A Single Bout of One-legged Exercise to Local Exhaustion Decreases Insulin Action in Non-exercised Muscle Leading to Decreased Whole-body Insulin Action

(2020) Dorte E. Steenberg et al.   DIABETES

Transcriptomic profiling of skeletal muscle adaptations to exercise and inactivity

(2020) Nicolas J. Pillon et al.   Nature Communications

Exercise Combats Hepatic Steatosis: Potential Mechanisms and Clinical Implications

(2020) John P. Thyfault et al.   DIABETES

Housing temperature influences exercise training adaptations in mice

(2020) Steffen H. Raun et al.   Nature Communications

Train like an athlete: applying exercise interventions to manage type 2 diabetes

(2020) Mladen Savikj et al.   DIABETOLOGIA

pH-Gated Succinate Secretion Regulates Muscle Remodeling in Response to Exercise

(2020) Anita Reddy et al.   CELL

Mechanisms Underlying Absent Training-Induced Improvement in Insulin Action in Lean, Hyperandrogenic Women With Polycystic Ovary Syndrome

(2020) Solvejg L. Hansen et al.   DIABETES

Early beta cell dysfunction vs insulin hypersecretion as the primary event in the pathogenesis of dysglycaemia

(2020) Nathalie Esser et al.   DIABETOLOGIA

The insulin‐sensitizing effect of a single exercise bout is similar in type I and type II human muscle fibres

(2020) Magnus R. Larsen et al.   JOURNAL OF PHYSIOLOGY-LONDON

Tuning fatty acid oxidation in skeletal muscle with dietary fat and exercise

(2020) Andreas Mæchel Fritzen et al.   Nature Reviews Endocrinology

Glucose management for exercise using continuous glucose monitoring ( CGM ) and intermittently scanned CGM ( isCGM ) systems in type 1 diabetes: position statement of the European Association for the Study of Diabetes ( EASD ) and of the International Society for Pediatric and Adolescent Diabetes ( ISPAD ) endorsed by JDRF and supported by the American Diabetes Association ( ADA )

(2020) Othmar Moser et al.   PEDIATRIC DIABETES

Prior exercise in humans redistributes intramuscular GLUT4 and enhances insulin-stimulated sarcolemmal and endosomal GLUT4 translocation

(2020) Jonas R. Knudsen et al.   Molecular Metabolism

Exercise training improves adipose tissue metabolism and vasculature regardless of baseline glucose tolerance and sex

(2020) Sanna Maria Honkala et al.   BMJ Open Diabetes Research & Care

Is GLUT4 translocation the answer to exercise-stimulated muscle glucose uptake?

(2020) Erik A. Richter   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

AMPK and TBC1D1 Regulate Muscle Glucose Uptake After - But Not During - Exercise and Contraction

(2019) Rasmus Kjøbsted et al.   DIABETES

TBC1D4 is Necessary for Enhancing Muscle Insulin Sensitivity in Response to AICAR and Contraction

(2019) Rasmus Kjøbsted et al.   DIABETES

Housing temperature affects the acute and chronic metabolic adaptations to exercise in mice

(2019) Greg L. McKie et al.   JOURNAL OF PHYSIOLOGY-LONDON

Insulin and β-adrenergic receptors mediate lipolytic and anti-lipolytic signalling that is not altered by type 2 diabetes in human adipocytes

(2019) Cecilia Jönsson et al.   BIOCHEMICAL JOURNAL

Aerobic exercise training improves hepatic and muscle insulin sensitivity, but reduces splanchnic glucose uptake in obese humans with type 2 diabetes

(2019) Justin M. Gregory et al.   Nutrition & Diabetes

Insulin‐induced membrane permeability to glucose in human muscles at rest and following exercise

(2019) Glenn K. McConell et al.   JOURNAL OF PHYSIOLOGY-LONDON

Cytosolic ROS production by NADPH oxidase 2 regulates muscle glucose uptake during exercise

(2019) Carlos Henríquez-Olguin et al.   Nature Communications

Exercise training protects human and rodent β cells against endoplasmic reticulum stress and apoptosis

(2018) Flavia M. M. Paula et al.   FASEB JOURNAL

Rac1 muscle knockout exacerbates the detrimental effect of high-fat diet on insulin-stimulated muscle glucose uptake independently of Akt

(2018) Steffen H. Raun et al.   JOURNAL OF PHYSIOLOGY-LONDON

GeneXX: an online tool for the exploration of transcript changes in skeletal muscle associated with exercise

(2018) Saskia Reibe et al.   PHYSIOLOGICAL GENOMICS

Molecular Regulation of Fatty Acid Oxidation in Skeletal Muscle during Aerobic Exercise

(2018) Anne-Marie Lundsgaard et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Maintenance of Skeletal Muscle Mitochondria in Health, Exercise, and Aging

(2018) David A. Hood et al.   Annual Review of Physiology

Quantitative proteomic characterization of cellular pathways associated with altered insulin sensitivity in skeletal muscle following high-fat diet feeding and exercise training

(2018) Maximilian Kleinert et al.   Scientific Reports

Effects of one-legged High-intensity Interval Training on insulin-mediated skeletal muscle glucose homeostasis in patients with type 2 diabetes

(2018) Flemming Dela et al.   Acta Physiologica

Molecular adaptations in human subcutaneous adipose tissue after ten weeks of endurance exercise training in healthy males

(2018) Simon Riis et al.   JOURNAL OF APPLIED PHYSIOLOGY

Once is enough for acute exercise benefits on insulin sensitivity

(2018) Gregory D. Cartee   JOURNAL OF PHYSIOLOGY-LONDON

Exercise training reduces the insulin-sensitizing effect of a single bout of exercise in human skeletal muscle

(2018) Dorte E. Steenberg et al.   JOURNAL OF PHYSIOLOGY-LONDON

The impact of exercise on mitochondrial dynamics and the role of Drp1 in exercise performance and training adaptations in skeletal muscle

(2018) Timothy M. Moore et al.   Molecular Metabolism

Exercise training and metformin, but not exercise training alone, decreases insulin production and increases insulin clearance in adults with prediabetes

(2017) Richard Viskochil et al.   JOURNAL OF APPLIED PHYSIOLOGY

Ablating the protein TBC1D1 impairs contraction-induced sarcolemmal glucose transporter 4 redistribution but not insulin-mediated responses in rats

(2017) Jamie Whitfield et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mammalian target of rapamycin complex 2 regulates muscle glucose uptake during exercise in mice

(2017) Maximilian Kleinert et al.   JOURNAL OF PHYSIOLOGY-LONDON

Enhanced Muscle Insulin Sensitivity After Contraction/Exercise Is Mediated by AMPK

(2016) Rasmus Kjøbsted et al.   DIABETES

Rac1 governs exercise-stimulated glucose uptake in skeletal muscle through regulation of GLUT4 translocation in mice

(2016) Lykke Sylow et al.   JOURNAL OF PHYSIOLOGY-LONDON

Exercise-stimulated glucose uptake — regulation and implications for glycaemic control

(2016) Lykke Sylow et al.   Nature Reviews Endocrinology

Globular adiponectin controls insulin-mediated vasoreactivity in muscle through AMPKα2

(2016) Michiel P. de Boer et al.   VASCULAR PHARMACOLOGY

Mechanisms for greater insulin-stimulated glucose uptake in normal and insulin-resistant skeletal muscle after acute exercise

(2015) Gregory D. Cartee   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Understanding the Cellular and Molecular Mechanisms of Physical Activity-Induced Health Benefits

(2015) P. Darrell Neufer et al.   Cell Metabolism

The RabGAP TBC1D1 Plays a Central Role in Exercise-Regulated Glucose Metabolism in Skeletal Muscle

(2015) Jacqueline Stöckli et al.   DIABETES

Increased Skeletal Muscle Capillarization Independently Enhances Insulin Sensitivity in Older Adults After Exercise Training and Detraining

(2015) Steven J. Prior et al.   DIABETES

A Novel Role for Subcutaneous Adipose Tissue in Exercise-Induced Improvements in Glucose Homeostasis

(2015) Kristin I. Stanford et al.   DIABETES

Effects of Exercise Training on Regulation of Skeletal Muscle Glucose Metabolism in Elderly Men

(2015) Rasmus Sjørup Biensø et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Human Muscle Fiber Type–Specific Insulin Signaling: Impact of Obesity and Type 2 Diabetes

(2014) Peter H. Albers et al.   DIABETES

Postexercise Improvement in Insulin-Stimulated Glucose Uptake Occurs Concomitant With Greater AS160 Phosphorylation in Muscle From Normal and Insulin-Resistant Rats

(2014) C. M. Castorena et al.   DIABETES

Higher Insulin-sensitizing Response after Sprint Interval Compared to Continuous Exercise

(2014) J. Ortega et al.   INTERNATIONAL JOURNAL OF SPORTS MEDICINE

The Effect of Acute Exercise on Undercarboxylated Osteocalcin and Insulin Sensitivity in Obese Men

(2014) Itamar Levinger et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Two weekly sessions of combined aerobic and resistance exercise are sufficient to provide beneficial effects in subjects with Type 2 diabetes mellitus and metabolic syndrome

(2014) C. Fatone et al.   JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION

Contraction-stimulated glucose transport in muscle is controlled by AMPK and mechanical stress but not sarcoplasmatic reticulum Ca2+ release

(2014) Thomas E. Jensen et al.   Molecular Metabolism

Both resistance training and aerobic training reduce hepatic fat content in type 2 diabetic subjects with nonalcoholic fatty liver disease (the RAED2 randomized trial)

(2013) Elisabetta Bacchi et al.   HEPATOLOGY

Endurance Exercise Training Up-Regulates Lipolytic Proteins and Reduces Triglyceride Content in Skeletal Muscle of Obese Subjects

(2013) Katie Louche et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Acute exercise and physiological insulin induce distinct phosphorylation signatures on TBC1D1 and TBC1D4 proteins in human skeletal muscle

(2013) Jonas T. Treebak et al.   JOURNAL OF PHYSIOLOGY-LONDON

Exercise, GLUT4, and Skeletal Muscle Glucose Uptake

(2013) Erik A. Richter et al.   PHYSIOLOGICAL REVIEWS

Insulin Activation of Plasma Nonesterified Fatty Acid Uptake in Metabolic Syndrome

(2012) Maria A. Ramos-Roman et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Rac1 Is a Novel Regulator of Contraction-Stimulated Glucose Uptake in Skeletal Muscle

(2012) L. Sylow et al.   DIABETES

Exercise Alleviates Lipid-Induced Insulin Resistance in Human Skeletal Muscle-Signaling Interaction at the Level of TBC1 Domain Family Member 4

(2012) C. Pehmoller et al.   DIABETES

Resistance Versus Aerobic Exercise: Acute effects on glycemia in type 1 diabetes

(2012) J. E. Yardley et al.   DIABETES CARE

In Vivo, Fatty Acid Translocase (CD36) Critically Regulates Skeletal Muscle Fuel Selection, Exercise Performance, and Training-induced Adaptation of Fatty Acid Oxidation

(2012) Jay T. McFarlan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Acute exercise activates AMPK and eNOS in the mouse aorta

(2011) José M. Cacicedo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Independent and Combined Effects of Exercise Training and Metformin on Insulin Sensitivity in Individuals With Prediabetes

(2011) S. K. Malin et al.   DIABETES CARE

Low-volume high-intensity interval training reduces hyperglycemia and increases muscle mitochondrial capacity in patients with type 2 diabetes

(2011) Jonathan P. Little et al.   JOURNAL OF APPLIED PHYSIOLOGY

Endurance training stimulates growth and survival pathways and the redox balance in rat pancreatic islets

(2011) Vivian C. Calegari et al.   JOURNAL OF APPLIED PHYSIOLOGY

Lowering Physical Activity Impairs Glycemic Control in Healthy Volunteers

(2011) CATHERINE R. MIKUS et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Fiber Types in Mammalian Skeletal Muscles

(2011) Stefano Schiaffino et al.   PHYSIOLOGICAL REVIEWS

AMP-activated protein kinase (AMPK)  1 2 muscle null mice reveal an essential role for AMPK in maintaining mitochondrial content and glucose uptake during exercise

(2011) H. M. O'Neill et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exercise training increases sarcolemmal and mitochondrial fatty acid transport proteins in human skeletal muscle

(2010) Jason L. Talanian et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Impaired insulin-induced site-specific phosphorylation of TBC1 domain family, member 4 (TBC1D4) in skeletal muscle of type 2 diabetes patients is restored by endurance exercise-training

(2010) B. F. Vind et al.   DIABETOLOGIA

Effect of short-term exercise training on insulin sensitivity in obese and lean mares

(2010) D. M. POWELL et al.   EQUINE VETERINARY JOURNAL

Influence of Commonly Employed Resistance Exercise Protocols on Circulating IL-6 and Indices of Insulin Sensitivity

(2010) Melody D Phillips et al.   JOURNAL OF STRENGTH AND CONDITIONING RESEARCH

Effects of 7 days of exercise training on insulin sensitivity and responsiveness in type 2 diabetes mellitus

(2009) John P. Kirwan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Potential role of TBC1D4 in enhanced post-exercise insulin action in human skeletal muscle

(2009) J. T. Treebak et al.   DIABETOLOGIA

Adipose triglyceride lipase in human skeletal muscle is upregulated by exercise training

(2008) Thomas J. Alsted et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM