Exercise training and metformin, but not exercise training alone, decreases insulin production and increases insulin clearance in adults with prediabetes

Prevention by metformin of alterations induced by chronic exposure to high glucose in human islet beta cells is associated with preserved ATP/ADP ratio

(2014) M. Masini et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Low Concentrations of Metformin Suppress Glucose Production in Hepatocytes through AMP-activated Protein Kinase (AMPK)

(2014) Jia Cao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase

(2014) Anila K. Madiraju et al.   NATURE

Differences in insulin clearance between metabolically healthy and unhealthy obese subjects

(2013) Maria A. Marini et al.   ACTA DIABETOLOGICA

Pancreatic beta cell function following liraglutide-augmented weight loss in individuals with prediabetes: analysis of a randomised, placebo-controlled study

(2013) Sun H. Kim et al.   DIABETOLOGIA

Normal physical activity obliterates the deleterious effects of a high-caloric intake

(2013) Rikke Krogh-Madsen et al.   JOURNAL OF APPLIED PHYSIOLOGY

Metformin modifies the exercise training effects on risk factors for cardiovascular disease in impaired glucose tolerant adults

(2013) Steven K. Malin et al.   Obesity

Hepatic insulin clearance is the primary determinant of insulin sensitivity in the normal dog

(2013) Marilyn Ader et al.   Obesity

Decreased Insulin Clearance in Individuals with Elevated 1-h Post-Load Plasma Glucose Levels

(2013) Maria Adelaide Marini et al.   PLoS One

Effects of endurance exercise training, metformin, and their combination on adipose tissue leptin and IL-10 secretion in OLETF rats

(2012) Nathan T. Jenkins et al.   JOURNAL OF APPLIED PHYSIOLOGY

The effects of a cafeteria diet on insulin production and clearance in rats

(2011) Anna Castell-Auví et al.   BRITISH JOURNAL OF NUTRITION

Independent and Combined Effects of Exercise Training and Metformin on Insulin Sensitivity in Individuals With Prediabetes

(2011) S. K. Malin et al.   DIABETES CARE

Proinsulin-to-C-peptide ratio versus proinsulin-to-insulin ratio in the prediction of incident diabetes: the Insulin Resistance Atherosclerosis Study (IRAS)

(2011) R. C. Loopstra-Masters et al.   DIABETOLOGIA

Preservation of β-Cell Function: The Key to Diabetes Prevention

(2011) Ralph A. DeFronzo et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Exercise and Type 2 Diabetes: The American College of Sports Medicine and the American Diabetes Association: joint position statement

(2010) S. R. Colberg et al.   DIABETES CARE

Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state

(2010) Marc Foretz et al.   JOURNAL OF CLINICAL INVESTIGATION