标题
Down the Iron Path: Mitochondrial Iron Homeostasis and Beyond
作者
关键词
-
出版物
Cells
Volume 10, Issue 9, Pages 2198
出版商
MDPI AG
发表日期
2021-08-26
DOI
10.3390/cells10092198
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- The Multifaceted Regulation of Mitochondria in Ferroptosis
- (2021) Hao Wu et al. Life-Basel
- Proteomics characterization of mitochondrial‐derived vesicles under oxidative stress
- (2021) Goutham Vasam et al. FASEB JOURNAL
- On Iron Metabolism and Its Regulation
- (2021) Anne-Cathrine S. Vogt et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- ABCB10 exports mitochondrial biliverdin, driving metabolic maladaptation in obesity
- (2021) Michael Shum et al. Science Translational Medicine
- The mitochondrial carrier SFXN1 is critical for complex III integrity and cellular metabolism
- (2021) Michelle Grace Acoba et al. Cell Reports
- Iron metabolism: pathophysiology and pharmacology
- (2021) Karolin Roemhild et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Mechanisms of Mitochondrial Iron-Sulfur Protein Biogenesis
- (2020) Roland Lill et al. Annual Review of Biochemistry
- Cysteine Toxicity Drives Age-Related Mitochondrial Decline by Altering Iron Homeostasis
- (2020) Casey E. Hughes et al. CELL
- Molecular mechanism of ISC iron-sulfur cluster biogenesis revealed by high-resolution native mass spectrometry
- (2020) Cheng-Wei Lin et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Maintaining Iron Homeostasis Is the Key Role of Lysosomal Acidity for Cell Proliferation
- (2020) Ross A. Weber et al. MOLECULAR CELL
- From Synthesis to Utilization: The Ins and Outs of Mitochondrial Heme
- (2020) Samantha A. Swenson et al. Cells
- From the discovery to molecular understanding of cellular iron-sulfur protein biogenesis
- (2020) Roland Lill BIOLOGICAL CHEMISTRY
- Mitochondrial–nuclear heme trafficking in budding yeast is regulated by GTPases that control mitochondrial dynamics and ER contact sites
- (2020) Osiris Martinez-Guzman et al. JOURNAL OF CELL SCIENCE
- Iron Metabolism in Obesity and Metabolic Syndrome
- (2020) Álvaro González-Domínguez et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- NUBPL mitochondrial disease: new patients and review of the genetic and clinical spectrum
- (2020) Virginia Kimonis et al. JOURNAL OF MEDICAL GENETICS
- Mitochondrial [4Fe-4S] protein assembly involves reductive [2Fe-2S] cluster fusion on ISCA1–ISCA2 by electron flow from ferredoxin FDX2
- (2020) Benjamin Dennis Weiler et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mechanistic concepts of iron-sulfur protein biogenesis in Biology
- (2020) Joseph J. Braymer et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Mössbauer and LC-ICP-MS investigation of iron trafficking between vacuoles and mitochondria in Vma2Δ Saccharomyces cerevisiae
- (2020) Joshua E. Kim et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mitochondrial iron metabolism and its role in diseases
- (2020) Jiayin Gao et al. CLINICA CHIMICA ACTA
- A recurring NFS1 pathogenic variant causes a mitochondrial disorder with variable intra-familial patient outcomes
- (2020) Tova Hershkovitz et al. Molecular Genetics and Metabolism Reports
- The mitochondrial heme metabolon: Insights into the complex(ity) of heme synthesis and distribution
- (2019) Robert B. Piel et al. MOLECULAR GENETICS AND METABOLISM
- Mechanism of frataxin “bypass” in human iron-sulfur cluster biosynthesis with implications for Friedreich’s ataxia
- (2019) Deepika Das et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mitochondria export iron-sulfur (Fe-S) and sulfur intermediates to the cytoplasm for Fe-S cluster assembly and tRNA thiolation in yeast
- (2019) Ashutosh K. Pandey et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Heme biosynthesis and the porphyrias
- (2019) John D. Phillips MOLECULAR GENETICS AND METABOLISM
- Mechanism of activation of the human cysteine desulfurase complex by frataxin
- (2019) Shachin Patra et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Effects of curcumin on mitochondria in neurodegenerative diseases
- (2019) Hossein Bagheri et al. BIOFACTORS
- PGRMC2 is an intracellular haem chaperone critical for adipocyte function
- (2019) Andrea Galmozzi et al. NATURE
- Physiologically relevant reconstitution of iron-sulfur cluster biosynthesis uncovers persulfide-processing functions of ferredoxin-2 and frataxin
- (2019) Sylvain Gervason et al. Nature Communications
- Making and breaking heme
- (2019) Arianna I. Celis et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Pathogenic variants in NUBPL result in failure to assemble the matrix arm of complex I and cause a complex leukoencephalopathy with thalamic involvement
- (2019) Marisa W. Friederich et al. MOLECULAR GENETICS AND METABOLISM
- Sideroflexin 4 affects Fe-S cluster biogenesis, iron metabolism, mitochondrial respiration and heme biosynthetic enzymes
- (2019) Bibbin T. Paul et al. Scientific Reports
- Impaired lysosomal acidification triggers iron deficiency and inflammation in vivo
- (2019) King Faisal Yambire et al. eLife
- A novel complex neurological phenotype due to a homozygous mutation in FDX2
- (2018) Juliana Gurgel-Giannetti et al. BRAIN
- Further delineation of the phenotypic spectrum of ISCA2 defect: A report of ten new cases
- (2018) Majid Alfadhel et al. EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY
- Transferrin and transferrin receptors update
- (2018) Hiroshi Kawabata FREE RADICAL BIOLOGY AND MEDICINE
- ISCA1 mutation in a patient with infantile-onset leukodystrophy causes defects in mitochondrial [4Fe–4S] proteins
- (2018) Alessandra Torraco et al. HUMAN MOLECULAR GENETICS
- Loss-of-function mutations in ISCA2 disrupt 4Fe-4S cluster machinery and cause a fatal leukodystrophy with hyperglycinemia and mtDNA depletion
- (2018) Joseph T. Alaimo et al. HUMAN MUTATION
- Neonatal mitochondrial leukoencephalopathy with brain and spinal involvement and high lactate: expanding the phenotype of ISCA2 gene mutations
- (2018) Irene Toldo et al. METABOLIC BRAIN DISEASE
- Mitochondrial cytochrome c oxidase biogenesis: Recent developments
- (2018) Alba Timón-Gómez et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- A role for divalent metal transporter (DMT1) in mitochondrial uptake of iron and manganese
- (2018) Natascha A. Wolff et al. Scientific Reports
- Ferritinophagy/ferroptosis: Iron-related newcomers in human diseases
- (2018) Mingzhu Tang et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Mitochondrial Iron in Human Health and Disease
- (2018) Diane M. Ward et al. Annual Review of Physiology
- The molecular genetics of sideroblastic anemia
- (2018) Sarah Ducamp et al. BLOOD
- Iron metabolism under conditions of ineffective erythropoiesis in β-thalassemia
- (2018) Stefano Rivella BLOOD
- SFXN1 is a mitochondrial serine transporter required for one-carbon metabolism
- (2018) Nora Kory et al. SCIENCE
- Cell Biology of the Mitochondrion
- (2017) Alexander M. van der Bliek et al. GENETICS
- Specialized function of yeast Isa1 and Isa2 proteins in the maturation of mitochondrial [4Fe-4S] proteins.
- (2017) Ulrich Mühlenhoff et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cytosolic iron chaperones: Proteins delivering iron cofactors in the cytosol of mammalian cells
- (2017) Caroline C. Philpott et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Ascorbate peroxidase proximity labeling coupled with biochemical fractionation identifies promoters of endoplasmic reticulum–mitochondrial contacts
- (2017) Il-Taeg Cho et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Iron–sulfur cluster biogenesis and trafficking in mitochondria
- (2017) Joseph J. Braymer et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Homozygous p.(Glu87Lys) variant in ISCA1 is associated with a multiple mitochondrial dysfunctions syndrome
- (2017) Anju Shukla et al. JOURNAL OF HUMAN GENETICS
- Cell Biology of the Mitochondrion
- (2017) Alexander M. van der Bliek et al. GENETICS
- Mitochondrial Iron Metabolism and Its Role in Neurodegeneration
- (2017) Maxx P. Horowitz et al. JOURNAL OF ALZHEIMERS DISEASE
- Heme Mobilization in Animals: A Metallolipid’s Journey
- (2016) Amit R. Reddi et al. ACCOUNTS OF CHEMICAL RESEARCH
- Iron and cancer: recent insights
- (2016) David H. Manz et al. Annals of the New York Academy of Sciences
- Labile Low-Molecular-Mass Metal Complexes in Mitochondria: Trials and Tribulations of a Burgeoning Field
- (2016) Paul A. Lindahl et al. BIOCHEMISTRY
- Erythroid cell mitochondria receive endosomal iron by a “kiss-and-run” mechanism
- (2016) Amel Hamdi et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- NSUN3 and ABH1 modify the wobble position of mt‐tRNAMetto expand codon recognition in mitochondrial translation
- (2016) Sara Haag et al. EMBO JOURNAL
- Reduction in mitochondrial iron alleviates cardiac damage during injury
- (2016) H.-C. Chang et al. EMBO Molecular Medicine
- Endosome–mitochondria interactions are modulated by iron release from transferrin
- (2016) Anupam Das et al. JOURNAL OF CELL BIOLOGY
- Novel mutations in IBA57 are associated with leukodystrophy and variable clinical phenotypes
- (2016) Alessandra Torraco et al. JOURNAL OF NEUROLOGY
- Regulators of Iron Homeostasis: New Players in Metabolism, Cell Death, and Disease
- (2016) Alexander R. Bogdan et al. TRENDS IN BIOCHEMICAL SCIENCES
- Mitochondria and Iron: current questions
- (2016) Bibbin T. Paul et al. Expert Review of Hematology
- Diagnosis and management of congenital dyserythropoietic anemias
- (2016) Antonella Gambale et al. Expert Review of Hematology
- Overlap of copper and iron uptake systems in mitochondria inSaccharomyces cerevisiae
- (2016) Katherine E. Vest et al. Open Biology
- Mitochondrial Bol1 and Bol3 function as assembly factors for specific iron-sulfur proteins
- (2016) Marta A Uzarska et al. eLife
- Selective sorting and destruction of mitochondrial membrane proteins in aged yeast
- (2016) Adam L Hughes et al. eLife
- Role of Nfu1 and Bol3 in iron-sulfur cluster transfer to mitochondrial clients
- (2016) Andrew Melber et al. eLife
- The mitochondrial acyl carrier protein (ACP) coordinates mitochondrial fatty acid synthesis with iron sulfur cluster biogenesis
- (2016) Jonathan G Van Vranken et al. eLife
- Parkinson’s Disease: The Mitochondria-Iron Link
- (2016) Yorka Muñoz et al. Parkinsons Disease
- The Human Iron–Sulfur Assembly Complex Catalyzes the Synthesis of [2Fe-2S] Clusters on ISCU2 That Can Be Transferred to Acceptor Molecules
- (2015) Nicholas G. Fox et al. BIOCHEMISTRY
- Frataxin Accelerates [2Fe-2S] Cluster Formation on the Human Fe–S Assembly Complex
- (2015) Nicholas G. Fox et al. BIOCHEMISTRY
- Cellular iron uptake, trafficking and metabolism: Key molecules and mechanisms and their roles in disease
- (2015) D.J.R. Lane et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Biogenesis of cytosolic and nuclear iron–sulfur proteins and their role in genome stability
- (2015) Viktoria Désirée Paul et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Iron –sulfur cluster biogenesis in mammalian cells: New insights into the molecular mechanisms of cluster delivery
- (2015) Nunziata Maio et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Congenital sideroblastic anemia due to mutations in the mitochondrial HSP70 homologue HSPA9
- (2015) K. Schmitz-Abe et al. BLOOD
- The BioPlex Network: A Systematic Exploration of the Human Interactome
- (2015) Edward L. Huttlin et al. CELL
- Iron Regulatory Protein 1 Sustains Mitochondrial Iron Loading and Function in Frataxin Deficiency
- (2015) Alain Martelli et al. Cell Metabolism
- Compartmentalization of iron between mitochondria and the cytosol and its regulation
- (2015) Ulrich Mühlenhoff et al. EUROPEAN JOURNAL OF CELL BIOLOGY
- Cancer cells with irons in the fire
- (2015) Laura M. Bystrom et al. FREE RADICAL BIOLOGY AND MEDICINE
- Mutation of the iron-sulfur cluster assembly gene IBA57 causes fatal infantile leukodystrophy
- (2015) François-Guillaume Debray et al. JOURNAL OF INHERITED METABOLIC DISEASE
- Fe/S protein assembly gene IBA57 mutation causes hereditary spastic paraplegia
- (2015) A. Lossos et al. NEUROLOGY
- Identification of the Mitochondrial Heme Metabolism Complex
- (2015) Amy E. Medlock et al. PLoS One
- Mitochondrial cytochrome c biogenesis: no longer an enigma
- (2015) Shalon E. Babbitt et al. TRENDS IN BIOCHEMICAL SCIENCES
- Mammalian frataxin directly enhances sulfur transfer of NFS1 persulfide to both ISCU and free thiols
- (2015) Aubérie Parent et al. Nature Communications
- Increased Heme Levels in the Heart Lead to Exacerbated Ischemic Injury
- (2015) Konrad Teodor Sawicki et al. Journal of the American Heart Association
- Chaperone protein involved in transmembrane transport of iron
- (2014) Izumi Yanatori et al. BIOCHEMICAL JOURNAL
- Human Frataxin Activates Fe–S Cluster Biosynthesis by Facilitating Sulfur Transfer Chemistry
- (2014) Jennifer Bridwell-Rabb et al. BIOCHEMISTRY
- Mammalian Fe–S cluster biogenesis and its implication in disease
- (2014) Lena K. Beilschmidt et al. BIOCHIMIE
- Impact of iron overload and potential benefit from iron chelation in low-risk myelodysplastic syndrome
- (2014) N. Shenoy et al. BLOOD
- Heterozygous missense mutations in the GLRX5 gene cause sideroblastic anemia in a Chinese patient
- (2014) G. Liu et al. BLOOD
- Control of Metazoan Heme Homeostasis by a Conserved Multidrug Resistance Protein
- (2014) Tamara Korolnek et al. Cell Metabolism
- Cochaperone Binding to LYR Motifs Confers Specificity of Iron Sulfur Cluster Delivery
- (2014) Nunziata Maio et al. Cell Metabolism
- A structural model for glutathione-complexed iron–sulfur cluster as a substrate for ABCB7-type transporters
- (2014) Wenbin Qi et al. CHEMICAL COMMUNICATIONS
- Heme Enzyme Structure and Function
- (2014) Thomas L. Poulos CHEMICAL REVIEWS
- A new pathway for mitochondrial quality control: mitochondrial-derived vesicles
- (2014) A. Sugiura et al. EMBO JOURNAL
- Evidence for mitochondrial localization of divalent metal transporter 1 (DMT1)
- (2014) Natascha A. Wolff et al. FASEB JOURNAL
- Iron Regulatory Protein-1 Protects against Mitoferrin-1-deficient Porphyria
- (2014) Jacky Chung et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mechanisms of Mitochondrial HolocytochromecSynthase and the Key Roles Played by Cysteines and Histidine of the Heme Attachment Site, Cys-XX-Cys-His
- (2014) Shalon E. Babbitt et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The HumanSLC25A33andSLC25A36Genes of Solute Carrier Family 25 Encode Two Mitochondrial Pyrimidine Nucleotide Transporters
- (2014) Maria Antonietta Di Noia et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Expression of the Yeast Cation Diffusion Facilitators Mmt1 and Mmt2 Affects Mitochondrial and Cellular Iron Homeostasis
- (2014) Liangtao Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Conserved Mitochondrial ATP-binding Cassette Transporter Exports Glutathione Polysulfide for Cytosolic Metal Cofactor Assembly
- (2014) Theresia A. Schaedler et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cardiotoxicity of doxorubicin is mediated through mitochondrial iron accumulation
- (2014) Yoshihiko Ichikawa et al. JOURNAL OF CLINICAL INVESTIGATION
- ISCA2mutation causes infantile neurodegenerative mitochondrial disorder
- (2014) Zuhair N Al-Hassnan et al. JOURNAL OF MEDICAL GENETICS
- The LYR protein subunit NB4M/NDUFA6 of mitochondrial complex I anchors an acyl carrier protein and is essential for catalytic activity
- (2014) H. Angerer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Iron chaperones PCBP1 and PCBP2 mediate the metallation of the dinuclear iron enzyme deoxyhypusine hydroxylase
- (2014) A. G. Frey et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Crystal Structures of Nucleotide-Free and Glutathione-Bound Mitochondrial ABC Transporter Atm1
- (2014) V. Srinivasan et al. SCIENCE
- Functional reconstitution of mitochondrial Fe/S cluster synthesis on Isu1 reveals the involvement of ferredoxin
- (2014) Holger Webert et al. Nature Communications
- Dysregulation of cellular iron metabolism in Friedreich ataxia: from primary iron-sulfur cluster deficit to mitochondrial iron accumulation
- (2014) Alain Martelli et al. Frontiers in Pharmacology
- Special delivery: distributing iron in the cytosol of mammalian cells
- (2014) Caroline C. Philpott et al. Frontiers in Pharmacology
- Macrocytic Anemia and Mitochondriopathy Resulting from a Defect in Sideroflexin 4
- (2013) Gordon J. Hildick-Smith et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Mitochondria and Metabolic Homeostasis
- (2013) Zhiyong Cheng et al. ANTIOXIDANTS & REDOX SIGNALING
- The mitochondrial carrier Rim2 co-imports pyrimidine nucleotides and iron
- (2013) Elisabeth M. Froschauer et al. BIOCHEMICAL JOURNAL
- Physiological and pathological roles of mitochondrial SLC25 carriers: Figure 1
- (2013) Manuel Gutiérrez-Aguilar et al. BIOCHEMICAL JOURNAL
- Variant non ketotic hyperglycinemia is caused by mutations in LIAS, BOLA3 and the novel gene GLRX5
- (2013) Peter R. Baker et al. BRAIN
- Fixing frataxin: ‘ironing out’ the metabolic defect in Friedreich's ataxia
- (2013) A Anzovino et al. BRITISH JOURNAL OF PHARMACOLOGY
- Iron and Diabetes Risk
- (2013) Judith A. Simcox et al. Cell Metabolism
- HRG1 Is Essential for Heme Transport from the Phagolysosome of Macrophages during Erythrophagocytosis
- (2013) Carine White et al. Cell Metabolism
- Deleterious mutation in FDX1L gene is associated with a novel mitochondrial muscle myopathy
- (2013) Ronen Spiegel et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Human ALKBH7 is required for alkylation and oxidation-induced programmed necrosis
- (2013) D. Fu et al. GENES & DEVELOPMENT
- Mutations in LYRM4, encoding iron–sulfur cluster biogenesis factor ISD11, cause deficiency of multiple respiratory chain complexes
- (2013) Sze Chern Lim et al. HUMAN MOLECULAR GENETICS
- Elevated FGF21 secretion, PGC-1α and ketogenic enzyme expression are hallmarks of iron–sulfur cluster depletion in human skeletal muscle
- (2013) Daniel R. Crooks et al. HUMAN MOLECULAR GENETICS
- Mutation of the iron-sulfur cluster assembly gene IBA57 causes severe myopathy and encephalopathy
- (2013) Nikhita Ajit Bolar et al. HUMAN MOLECULAR GENETICS
- Human Mitochondrial Chaperone (mtHSP70) and Cysteine Desulfurase (NFS1) Bind Preferentially to the Disordered Conformation, Whereas Co-chaperone (HSC20) Binds to the Structured Conformation of the Iron-Sulfur Cluster Scaffold Protein (ISCU)
- (2013) Kai Cai et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Frataxin: a protein in search for a function
- (2013) Annalisa Pastore et al. JOURNAL OF NEUROCHEMISTRY
- The Heme a Synthase Cox15 Associates with Cytochrome c Oxidase Assembly Intermediates during Cox1 Maturation
- (2013) B. Bareth et al. MOLECULAR AND CELLULAR BIOLOGY
- Heme and FLVCR-related transporter families SLC48 and SLC49
- (2013) Anwar A. Khan et al. MOLECULAR ASPECTS OF MEDICINE
- The mitochondrial Hsp70 chaperone Ssq1 facilitates Fe/S cluster transfer from Isu1 to Grx5 by complex formation
- (2013) Marta A. Uzarska et al. MOLECULAR BIOLOGY OF THE CELL
- NUBPL mutations in patients with complex I deficiency and a distinct MRI pattern
- (2013) S. H. Kevelam et al. NEUROLOGY
- Enhanced Heme Function and Mitochondrial Respiration Promote the Progression of Lung Cancer Cells
- (2013) Jagmohan Hooda et al. PLoS One
- Exome sequencing identifiesNFS1deficiency in a novel Fe-S cluster disease, infantile mitochondrial complex II/III deficiency
- (2013) Sali M. K. Farhan et al. Molecular Genetics & Genomic Medicine
- Mammalian Iron Homeostasis in Health and Disease: Uptake, Storage, Transport, and Molecular Mechanisms of Action
- (2012) Alfons Lawen et al. ANTIOXIDANTS & REDOX SIGNALING
- Persulfide formation on mitochondrial cysteine desulfurase: enzyme activation by a eukaryote-specific interacting protein and Fe–S cluster synthesis
- (2012) Alok Pandey et al. BIOCHEMICAL JOURNAL
- Mitochondrial quality control by the ubiquitin–proteasome system: Figure 1
- (2012) Eric B. Taylor et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- LYRM7/MZM1L is a UQCRFS1 chaperone involved in the last steps of mitochondrial Complex III assembly in human cells
- (2012) Ester Sánchez et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- One ring to rule them all: Trafficking of heme and heme synthesis intermediates in the metazoans
- (2012) Iqbal Hamza et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Cellular and mitochondrial iron homeostasis in vertebrates
- (2012) Caiyong Chen et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Structure, function, and assembly of heme centers in mitochondrial respiratory complexes
- (2012) Hyung J. Kim et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Intracellular iron trafficking: role of cytosolic ligands
- (2012) Maya Shvartsman et al. BIOMETALS
- Iron speciation in the cytosol: an overview
- (2012) Robert C. Hider et al. DALTON TRANSACTIONS
- Biogenesis of iron-sulfur clusters in mammalian cells: new insights and relevance to human disease
- (2012) T. A. Rouault Disease Models & Mechanisms
- Mitoferrin-2-dependent Mitochondrial Iron Uptake Sensitizes Human Head and Neck Squamous Carcinoma Cells to Photodynamic Therapy
- (2012) Hsin-I Hung et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Oligomerization of HemeoSynthase in Cytochrome Oxidase Biogenesis Is Mediated by Cytochrome Oxidase Assembly Factor Coa2
- (2012) Oleh Khalimonchuk et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The mitochondrial heme exporter FLVCR1b mediates erythroid differentiation
- (2012) Deborah Chiabrando et al. JOURNAL OF CLINICAL INVESTIGATION
- Homozygous missense mutation in BOLA3 causes multiple mitochondrial dysfunctions syndrome in two siblings
- (2012) Tobias B. Haack et al. JOURNAL OF INHERITED METABOLIC DISEASE
- Mammalian Frataxin Controls Sulfur Production and Iron Entry during de Novo Fe4S4 Cluster Assembly
- (2012) Florent Colin et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- The human mitochondrial ISCA1, ISCA2, and IBA57 proteins are required for [4Fe-4S] protein maturation
- (2012) Alex D. Sheftel et al. MOLECULAR BIOLOGY OF THE CELL
- Reduction of Mitoferrin Results in Abnormal Development and Extended Lifespan in Caenorhabditis elegans
- (2012) Yaguang Ren et al. PLoS One
- VDAC1: from structure to cancer therapy
- (2012) Varda Shoshan-Barmatz et al. Frontiers in Oncology
- Mutations in Iron-Sulfur Cluster Scaffold Genes NFU1 and BOLA3 Cause a Fatal Deficiency of Multiple Respiratory Chain and 2-Oxoacid Dehydrogenase Enzymes
- (2011) Jessie M. Cameron et al. AMERICAN JOURNAL OF HUMAN GENETICS
- A Fatal Mitochondrial Disease Is Associated with Defective NFU1 Function in the Maturation of a Subset of Mitochondrial Fe-S Proteins
- (2011) Aleix Navarro-Sastre et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Infantile cardioencephalopathy due to a COX15 gene defect: Report and review
- (2011) Majid Alfadhel et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- Proteomic analysis of lipid raft-enriched membranes isolated from internal organelles
- (2011) Chloe N. Poston et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Rim2, a pyrimidine nucleotide exchanger, is needed for iron utilization in mitochondria
- (2011) Heeyong Yoon et al. BIOCHEMICAL JOURNAL
- Role of Surf1 in heme recruitment for bacterial COX biogenesis
- (2011) Achim Hannappel et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Both human ferredoxins 1 and 2 and ferredoxin reductase are important for iron-sulfur cluster biogenesis
- (2011) Yanbo Shi et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Mechanism of glutaredoxin—ISU [2Fe–2S] cluster exchange
- (2011) Wenbin Qi et al. CHEMICAL COMMUNICATIONS
- Key Players and Their Role During Mitochondrial Iron-Sulfur Cluster Biosynthesis
- (2011) Swati Rawat et al. CHEMISTRY-A EUROPEAN JOURNAL
- Abnormal mitoferrin-1 expression in patients with erythropoietic protoporphyria
- (2011) Yongming Wang et al. EXPERIMENTAL HEMATOLOGY
- HSC20 interacts with frataxin and is involved in iron–sulfur cluster biogenesis and iron homeostasis
- (2011) Yuxi Shan et al. HUMAN MOLECULAR GENETICS
- Eukaryotic DNA polymerases require an iron-sulfur cluster for the formation of active complexes
- (2011) Daili J A Netz et al. Nature Chemical Biology
- A novel deletion–insertion mutation identified in exon 3 of FXN in two siblings with a severe Friedreich ataxia phenotype
- (2011) Marguerite V. Evans-Galea et al. NEUROGENETICS
- Mammalian Frataxin: An Essential Function for Cellular Viability through an Interaction with a Preformed ISCU/NFS1/ISD11 Iron-Sulfur Assembly Complex
- (2011) Stéphane Schmucker et al. PLoS One
- The rice mitochondrial iron transporter is essential for plant growth
- (2011) Khurram Bashir et al. Nature Communications
- Monothiol glutaredoxin Grx5 interacts with Fe–S scaffold proteins Isa1 and Isa2 and supports Fe–S assembly and DNA integrity in mitochondria of fission yeast
- (2010) Kyoung-Dong Kim et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Transferrin-iron routing to the cytosol and mitochondria as studied by live and real-time fluorescence
- (2010) Maya Shvartsman et al. BIOCHEMICAL JOURNAL
- Human Iron−Sulfur Cluster Assembly, Cellular Iron Homeostasis, and Disease
- (2010) Hong Ye et al. BIOCHEMISTRY
- Human Frataxin Is an Allosteric Switch That Activates the Fe−S Cluster Biosynthetic Complex
- (2010) Chi-Lin Tsai et al. BIOCHEMISTRY
- Cytosolic and mitochondrial ferritins in the regulation of cellular iron homeostasis and oxidative damage
- (2010) Paolo Arosio et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Differences in RNA processing underlie the tissue specific phenotype of ISCU myopathy
- (2010) Petter S. Sanaker et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Ferrochelatase forms an oligomeric complex with mitoferrin-1 and Abcb10 for erythroid heme biosynthesis
- (2010) W. Chen et al. BLOOD
- A Mammalian Siderophore Synthesized by an Enzyme with a Bacterial Homolog Involved in Enterobactin Production
- (2010) Laxminarayana R. Devireddy et al. CELL
- Cytosolic Monothiol Glutaredoxins Function in Intracellular Iron Sensing and Trafficking via Their Bound Iron-Sulfur Cluster
- (2010) Ulrich Mühlenhoff et al. Cell Metabolism
- Human copper homeostasis: a network of interconnected pathways
- (2010) Svetlana Lutsenko CURRENT OPINION IN CHEMICAL BIOLOGY
- Hereditary sideroblastic anaemia and autosomal inheritance of erythrocyte dimorphism in a Dutch family
- (2010) G. D. van Waveren Hogervorst et al. EUROPEAN JOURNAL OF HAEMATOLOGY
- Understanding the molecular mechanisms of Friedreich's ataxia to develop therapeutic approaches
- (2010) S. Schmucker et al. HUMAN MOLECULAR GENETICS
- Characterization of the human HSC20, an unusual DnaJ type III protein, involved in iron–sulfur cluster biogenesis
- (2010) Helge Uhrigshardt et al. HUMAN MOLECULAR GENETICS
- Normal and Friedreich Ataxia Cells Express Different Isoforms of Frataxin with Complementary Roles in Iron-Sulfur Cluster Assembly
- (2010) Oleksandr Gakh et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Genetic and Biochemical Analysis of High Iron Toxicity in Yeast
- (2010) Huilan Lin et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- ZRT/IRT-like Protein 14 (ZIP14) Promotes the Cellular Assimilation of Iron from Transferrin
- (2010) Ningning Zhao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Glutaredoxin 5 deficiency causes sideroblastic anemia by specifically impairing heme biosynthesis and depleting cytosolic iron in human erythroblasts
- (2010) Hong Ye et al. JOURNAL OF CLINICAL INVESTIGATION
- Porphyrias
- (2010) Hervé Puy et al. LANCET
- The Fowler Syndrome-Associated Protein FLVCR2 Is an Importer of Heme
- (2010) S. P. Duffy et al. MOLECULAR AND CELLULAR BIOLOGY
- Analysis of Leigh Syndrome Mutations in the Yeast SURF1 Homolog Reveals a New Member of the Cytochrome Oxidase Assembly Factor Family
- (2010) M. Bestwick et al. MOLECULAR AND CELLULAR BIOLOGY
- High-throughput, pooled sequencing identifies mutations in NUBPL and FOXRED1 in human complex I deficiency
- (2010) Sarah E Calvo et al. NATURE GENETICS
- MicroRNA-210 Regulates Mitochondrial Free Radical Response to Hypoxia and Krebs Cycle in Cancer Cells by Targeting Iron Sulfur Cluster Protein ISCU
- (2010) Elena Favaro et al. PLoS One
- Humans possess two mitochondrial ferredoxins, Fdx1 and Fdx2, with distinct roles in steroidogenesis, heme, and Fe/S cluster biosynthesis
- (2010) A. D. Sheftel et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural bases for the interaction of frataxin with the central components of iron–sulphur cluster assembly
- (2010) Filippo Prischi et al. Nature Communications
- Structural Basis for Fe–S Cluster Assembly and tRNA Thiolation Mediated by IscS Protein–Protein Interactions
- (2010) Rong Shi et al. PLOS BIOLOGY
- Mitochondrial Glutathione, a Key Survival Antioxidant
- (2009) Montserrat Marí et al. ANTIOXIDANTS & REDOX SIGNALING
- Overexpression ofDrosophila mitoferrinin l(2)mbn cells results in dysregulation of Fer1HCH expression
- (2009) Christoph Metzendorf et al. BIOCHEMICAL JOURNAL
- The Yeast Iron Regulatory Proteins Grx3/4 and Fra2 Form Heterodimeric Complexes Containing a [2Fe-2S] Cluster with Cysteinyl and Histidyl Ligation
- (2009) Haoran Li et al. BIOCHEMISTRY
- The yeast mitochondrial carrier proteins Mrs3p/Mrs4p mediate iron transport across the inner mitochondrial membrane
- (2009) Elisabeth M. Froschauer et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Clinical manifestation and a new ISCU mutation in iron–sulphur cluster deficiency myopathy
- (2009) Gittan Kollberg et al. BRAIN
- Discovery of Genes Essential for Heme Biosynthesis through Large-Scale Gene Expression Analysis
- (2009) Roland Nilsson et al. Cell Metabolism
- Mammalian iron transport
- (2009) Gregory Jon Anderson et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Iron(iii) citrate speciation in aqueous solution
- (2009) Andre M. N. Silva et al. DALTON TRANSACTIONS
- The Interaction of Mitochondrial Iron with Manganese Superoxide Dismutase
- (2009) Amornrat Naranuntarat et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Surf1, Associated with Leigh Syndrome in Humans, Is a Heme-binding Protein in Bacterial Oxidase Biogenesis
- (2009) Freya A. Bundschuh et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The ins and outs of mitochondrial iron-loading: the metabolic defect in Friedreich’s ataxia
- (2009) Des R. Richardson et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Cytochrome c Biogenesis: Mechanisms for Covalent Modifications and Trafficking of Heme and for Heme-Iron Redox Control
- (2009) R. G. Kranz et al. MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS
- Human Ind1, an Iron-Sulfur Cluster Assembly Factor for Respiratory Complex I
- (2009) A. D. Sheftel et al. MOLECULAR AND CELLULAR BIOLOGY
- The Role of Coa2 in Hemylation of Yeast Cox1 Revealed by Its Genetic Interaction with Cox10
- (2009) M. Bestwick et al. MOLECULAR AND CELLULAR BIOLOGY
- Formation of the Redox Cofactor Centers during Cox1 Maturation in Yeast Cytochrome Oxidase
- (2009) O. Khalimonchuk et al. MOLECULAR AND CELLULAR BIOLOGY
- Bacterial frataxin CyaY is the gatekeeper of iron-sulfur cluster formation catalyzed by IscS
- (2009) Salvatore Adinolfi et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Elucidation of the mechanism of mitochondrial iron loading in Friedreich's ataxia by analysis of a mouse mutant
- (2009) M. L.-H. Huang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Abcb10 physically interacts with mitoferrin-1 (Slc25a37) to enhance its stability and function in the erythroid mitochondria
- (2009) W. Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Splice Mutation in the Iron-Sulfur Cluster Scaffold Protein ISCU Causes Myopathy with Exercise Intolerance
- (2008) Fanny Mochel et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Systemic Iron Homeostasis and the Iron-Responsive Element/Iron-Regulatory Protein (IRE/IRP) Regulatory Network
- (2008) Martina U. Muckenthaler et al. Annual Review of Nutrition
- Diseases caused by defects of mitochondrial carriers: A review
- (2008) Ferdinando Palmieri BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Cargo-Selected Transport from the Mitochondria to Peroxisomes Is Mediated by Vesicular Carriers
- (2008) Margaret Neuspiel et al. CURRENT BIOLOGY
- Translocation of iron from lysosomes into mitochondria is a key event during oxidative stress-induced hepatocellular injury
- (2008) Akira Uchiyama et al. HEPATOLOGY
- Mitochondrial ferritin limits oxidative damage regulating mitochondrial iron availability: hypothesis for a protective role in Friedreich ataxia
- (2008) A. Campanella et al. HUMAN MOLECULAR GENETICS
- Myopathy with lactic acidosis is linked to chromosome 12q23.3-24.11 and caused by an intron mutation in the ISCU gene resulting in a splicing defect
- (2008) A. Olsson et al. HUMAN MOLECULAR GENETICS
- Body iron metabolism and pathophysiology of iron overload
- (2008) Yutaka Kohgo et al. INTERNATIONAL JOURNAL OF HEMATOLOGY
- Coa2 Is an Assembly Factor for Yeast Cytochrome c Oxidase Biogenesis That Facilitates the Maturation of Cox1
- (2008) F. Pierrel et al. MOLECULAR AND CELLULAR BIOLOGY
- Regulation of Mitochondrial Iron Import through Differential Turnover of Mitoferrin 1 and Mitoferrin 2
- (2008) P. N. Paradkar et al. MOLECULAR AND CELLULAR BIOLOGY
- Yeast mitochondria import ATP through the calcium-dependent ATP-Mg/Pi carrier Sal1p, and are ATP consumers during aerobic growth in glucose
- (2008) Javier Traba et al. MOLECULAR MICROBIOLOGY
- Haem homeostasis is regulated by the conserved and concerted functions of HRG-1 proteins
- (2008) Abbhirami Rajagopal et al. NATURE
- The Role of the Iron Transporter ABCB7 in Refractory Anemia with Ring Sideroblasts
- (2008) Jacqueline Boultwood et al. PLoS One
- A Heme Export Protein Is Required for Red Blood Cell Differentiation and Iron Homeostasis
- (2008) S. B. Keel et al. SCIENCE
- Special delivery from mitochondria to peroxisomes
- (2008) Uwe Schumann et al. TRENDS IN CELL BIOLOGY
- Iron–sulfur cluster biogenesis and human disease
- (2008) Tracey A. Rouault et al. TRENDS IN GENETICS
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