Identification of the Mitochondrial Heme Metabolism Complex

TMEM14C is required for erythroid mitochondrial heme metabolism

(2014) Yvette Y. Yien et al.   JOURNAL OF CLINICAL INVESTIGATION

Nitrate as a probe of cytochrome c surface: Crystallographic identification of crucial “hot spots” for protein–protein recognition

(2014) Matteo De March et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Abcb10 Role in Heme Biosynthesis In Vivo: Abcb10 Knockout in Mice Causes Anemia with Protoporphyrin IX and Iron Accumulation

(2014) M. Yamamoto et al.   MOLECULAR AND CELLULAR BIOLOGY

Enzyme clustering accelerates processing of intermediates through metabolic channeling

(2014) Michele Castellana et al.   NATURE BIOTECHNOLOGY

Iron availability modulates aberrant splicing of ferrochelatase through the iron- and 2-oxoglutarate dependent dioxygenase Jmjd6 and U2AF65

(2013) Jasmin Barman-Aksözen et al.   BLOOD CELLS MOLECULES AND DISEASES

ATP-Binding Cassette B10 Regulates Early Steps of Heme Synthesis

(2013) Marina Bayeva et al.   CIRCULATION RESEARCH

The MIntAct project—IntAct as a common curation platform for 11 molecular interaction databases

(2013) Sandra Orchard et al.   NUCLEIC ACIDS RESEARCH

Proteomic Mapping of Mitochondria in Living Cells via Spatially Restricted Enzymatic Tagging

(2013) H.-W. Rhee et al.   SCIENCE

Mitochondrial ABC transporters function: The role of ABCB10 (ABC-me) as a novel player in cellular handling of reactive oxygen species

(2012) Marc Liesa et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

One ring to rule them all: Trafficking of heme and heme synthesis intermediates in the metazoans

(2012) Iqbal Hamza et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Cellular and mitochondrial iron homeostasis in vertebrates

(2012) Caiyong Chen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

X-linked Sideroblastic Anemia Due to Carboxyl-terminal ALAS2 Mutations That Cause Loss of Binding to the β-Subunit of Succinyl-CoA Synthetase (SUCLA2)

(2012) David F. Bishop et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MMS19 Assembles Iron-Sulfur Proteins Required for DNA Metabolism and Genomic Integrity

(2012) O. Stehling et al.   SCIENCE

Human mitochondrial ATP-binding cassette transporter ABCB10 is required for efficient red blood cell development

(2011) Leilei Tang et al.   BRITISH JOURNAL OF HAEMATOLOGY

Ferrochelatase forms an oligomeric complex with mitoferrin-1 and Abcb10 for erythroid heme biosynthesis

(2010) W. Chen et al.   BLOOD

Structural insight into human variegate porphyria disease

(2010) Xiaohong Qin et al.   FASEB JOURNAL

Mitochondrial iron trafficking and the integration of iron metabolism between the mitochondrion and cytosol

(2010) D. R. Richardson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of human porphobilinogen deaminase at 2.8 Å: the molecular basis of acute intermittent porphyria

(2009) Raj Gill et al.   BIOCHEMICAL JOURNAL

Abcb10 physically interacts with mitoferrin-1 (Slc25a37) to enhance its stability and function in the erythroid mitochondria

(2009) W. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

C-Terminal Deletions in the ALAS2 Gene Lead to Gain of Function and Cause X-linked Dominant Protoporphyria without Anemia or Iron Overload

(2008) Sharon D. Whatley et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Identification of ZBP-89 as a Novel GATA-1-Associated Transcription Factor Involved in Megakaryocytic and Erythroid Development

(2008) A. J. Woo et al.   MOLECULAR AND CELLULAR BIOLOGY

Adenine Nucleotide Translocator Transports Haem Precursors into Mitochondria

(2008) Motoki Azuma et al.   PLoS One