标题
Role of IQGAP1 in Carcinogenesis
作者
关键词
-
出版物
Cancers
Volume 13, Issue 16, Pages 3940
出版商
MDPI AG
发表日期
2021-08-05
DOI
10.3390/cancers13163940
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
- (2021) Hyuna Sung et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Scaffolding Protein IQGAP1 is Dispensable But Its Overexpression Promotes Hepatocellular Carcinoma via YAP1 Signaling
- (2021) Evan R Delgado et al. MOLECULAR AND CELLULAR BIOLOGY
- IQGAP1 Is a Scaffold of the Core Proteins of the Hippo Pathway and Negatively Regulates the Pro-Apoptotic Signal Mediated by This Pathway
- (2021) Niall P. Quinn et al. Cells
- Role of IQGAP1 in Papillomavirus-Associated Head and Neck Tumorigenesis
- (2021) Tao Wei et al. Cancers
- Ubiquitination of the scaffold protein IQGAP1 diminishes its interaction with and activation of the Rho GTPase CDC42
- (2020) Laëtitia Gorisse et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Molecular regulation of the plasma membrane-proximal cellular steps involved in NK cell cytolytic function
- (2020) Prasad V. Phatarpekar et al. JOURNAL OF CELL SCIENCE
- Purpuric drug eruptions induced by EGFR tyrosine kinase inhibitors are associated with IQGAP1‐mediated increase in vascular permeability
- (2020) Yi‐Shuan Sheen et al. JOURNAL OF PATHOLOGY
- MmuPV1: A New Frontier in Animal Models of Papillomavirus Pathogenesis
- (2020) Megan E. Spurgeon et al. JOURNAL OF VIROLOGY
- The scaffold protein IQGAP1 is crucial for extravasation and metastasis
- (2020) Jess D. Hebert et al. Scientific Reports
- Transcriptomic Analysis of Pulmonary Microvascular Endothelial Cells with IQGAP1 Knockdown
- (2020) Shihong Su et al. DNA AND CELL BIOLOGY
- IQGAP2 Inhibits Migration and Invasion of Gastric Cancer Cells via Elevating SHIP2 Phosphatase Activity
- (2020) Liang Xu et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- An Infection-Based Murine Model for Papillomavirus-Associated Head and Neck Cancer
- (2020) Tao Wei et al. mBio
- E6-mediated activation of JNK drives EGFR signalling to promote proliferation and viral oncoprotein expression in cervical cancer
- (2020) Ethan L. Morgan et al. CELL DEATH AND DIFFERENTIATION
- A Novel In Vivo Infection Model To Study Papillomavirus-Mediated Disease of the Female Reproductive Tract
- (2019) Megan E. Spurgeon et al. mBio
- Differential Activation of ERK Signaling in HPV-Related Oropharyngeal Squamous Cell Carcinoma
- (2019) Chao Rong et al. Cancers
- Incidence and Demographic Burden of HPV-associated Oropharyngeal Head and Neck Cancers in the United States
- (2019) Brandon A Mahal et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- IQGAP1 promotes pancreatic cancer progression and epithelial-mesenchymal transition (EMT) through Wnt/β-catenin signaling
- (2019) Wei Hu et al. Scientific Reports
- Endogenous IQGAP1 and IQGAP3 do not functionally interact with Ras
- (2019) Chase J. Morgan et al. Scientific Reports
- The Specificity of EGF-Stimulated IQGAP1 Scaffold Towards the PI3K-Akt Pathway is Defined by the IQ3 motif
- (2019) Mo Chen et al. Scientific Reports
- Autocrine STAT3 activation in HPV positive cervical cancer through a virus-driven Rac1—NFκB—IL-6 signalling axis
- (2019) Ethan L. Morgan et al. PLoS Pathogens
- MAP4K3/GLK Promotes Lung Cancer Metastasis by Phosphorylating and Activating IQGAP1
- (2019) Huai-Chia Chuang et al. CANCER RESEARCH
- A PI3K/AKT Scaffolding Protein, IQ Motif–Containing GTPase Associating Protein 1 (IQGAP1), Promotes Head and Neck Carcinogenesis
- (2019) Tao Wei et al. CLINICAL CANCER RESEARCH
- IQGAP1 restrains T‐cell cosignaling mediated by OX40
- (2019) Yuko Okuyama et al. FASEB JOURNAL
- Identification of novel genetic variants predisposing to familial oral squamous cell carcinomas
- (2019) Yaping Huang et al. Cell Discovery
- Interleukin-6 promotes pancreatic cancer cell migration by rapidly activating the small GTPase CDC42
- (2018) Gina L. Razidlo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- MTA1 promotes viability and motility in nasopharyngeal carcinoma by modulating IQGAP1 expression
- (2018) Baocai Lu et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Over-expression of IQGAP1 indicates poor prognosis in head and neck squamous cell carcinoma
- (2018) Cong-Cong Wu et al. JOURNAL OF MOLECULAR HISTOLOGY
- Overexpression of IQGAP1 promotes the angiogenesis of esophageal squamous cell carcinoma through the AKT and ERK‑mediated VEGF‑VEGFR2 signaling pathway
- (2018) Chao‑Hui Li et al. ONCOLOGY REPORTS
- Ras GTPase-Activating-Like Protein IQGAP1 (IQGAP1) Promotes Breast Cancer Proliferation and Invasion and Correlates with Poor Clinical Outcomes
- (2018) Fanye Zeng et al. MEDICAL SCIENCE MONITOR
- IQ Domain-Containing GTPase-Activating Protein 1 Regulates Cytoskeletal Reorganization and Facilitates NKG2D-Mediated Mechanistic Target of Rapamycin Complex 1 Activation and Cytokine Gene Translation in Natural Killer Cells
- (2018) Alex M. Abel et al. Frontiers in Immunology
- miR‑124 inhibits cell growth through targeting IQGAP1 in colorectal cancer
- (2018) Jianyu Fan et al. Molecular Medicine Reports
- Activating Mutations in Pik3caContribute to Anal Carcinogenesis in the Presence or Absence of HPV-16 Oncogenes.
- (2018) Myeong-Kyun Shin et al. CLINICAL CANCER RESEARCH
- Regulation of extracellular matrix degradation and metastatic spread by IQGAP1 through endothelin-1 receptor signalling in ovarian cancer
- (2018) Lidia Chellini et al. MATRIX BIOLOGY
- IQGAP1 Maintains Pancreatic Ductal Adenocarcinoma Clonogenic Growth and Metastasis
- (2018) Joey H. Li et al. PANCREAS
- Downregulation of IQGAP2 Correlates with Prostate Cancer Recurrence and Metastasis
- (2018) Yanyun Xie et al. Translational Oncology
- LGR5 receptor promotes cell–cell adhesion in stem cells and colon cancer cells via the IQGAP1–Rac1 pathway
- (2017) Kendra S. Carmon et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Transforming Growth Factor-β (TGF-β) Directly Activates the JAK1-STAT3 Axis to Induce Hepatic Fibrosis in Coordination with the SMAD Pathway
- (2017) Liu-Ya Tang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The WW domain of the scaffolding protein IQGAP1 is neither necessary nor sufficient for binding to the MAPKs ERK1 and ERK2
- (2017) A. Jane Bardwell et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Rap1-cofilin pathway coordinates actin reorganization and MTOC polarization at the B-cell immune synapse
- (2017) Jia C. Wang et al. JOURNAL OF CELL SCIENCE
- Reduced expression of IQGAP2 and higher expression of IQGAP3 correlates with poor prognosis in cancers
- (2017) Dinesh Kumar et al. PLoS One
- IQ-domain GTPase-activating protein 1 promotes the malignant phenotype of invasive ductal breast carcinoma via canonical Wnt pathway
- (2017) Huan-Yu Zhao et al. TUMOR BIOLOGY
- Role of JNK signaling in oral cancer: A mini review
- (2017) Ioannis Gkouveris et al. TUMOR BIOLOGY
- Asparaginyl endopeptidase improves the resistance of microtubule-targeting drugs in gastric cancer through IQGAP1 modulating the EGFR/JNK/ERK signaling pathway
- (2017) Yuehong Cui et al. OncoTargets and Therapy
- IQGAP1 expression in hepatocellular carcinoma predicts poor prognosis by inducing epithelial-mesenchymal transition
- (2017) Chuan Li et al. Translational Cancer Research
- Rationale for anti-OX40 cancer immunotherapy
- (2016) Sandrine Aspeslagh et al. EUROPEAN JOURNAL OF CANCER
- Potential involvement of IQGAP1 in proliferation and metastasis of human pancreatic cancer
- (2016) Jiawei Chen Frontiers in Bioscience-Landmark
- IQGAP1 Binds to Yes-associated Protein (YAP) and Modulates Its Transcriptional Activity
- (2016) Samar Sayedyahossein et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Overexpression of CD44 is associated with the occurrence and migration of non-small cell lung cancer
- (2016) Guanghu Li et al. Molecular Medicine Reports
- Agonist-stimulated phosphatidylinositol-3,4,5-trisphosphate generation by scaffolded phosphoinositide kinases
- (2016) Suyong Choi et al. NATURE CELL BIOLOGY
- IQGAP1 gene silencing induces apoptosis and decreases the invasive capacity of human hepatocellular carcinoma cells
- (2016) Khairy MA Zoheir et al. TUMOR BIOLOGY
- Deletion of epidermal Rac1 inhibits HPV-8 induced skin papilloma formation and facilitates HPV-8- and UV-light induced skin carcinogenesis
- (2016) Jayesh Deshmukh et al. Oncotarget
- Deletion of IQGAP1 promotes Helicobacter pylori-induced gastric dysplasia in mice and acquisition of cancer stem cell properties in vitro
- (2016) Emilie Bessède et al. Oncotarget
- Preclinical evidence of multiple mechanisms underlying trastuzumab resistance in gastric cancer
- (2016) Chiara Arienti et al. Oncotarget
- Role of Ultraviolet Radiation in Papillomavirus-Induced Disease
- (2016) Aayushi Uberoi et al. PLoS Pathogens
- IQGAPs as Key Regulators of Actin-cytoskeleton Dynamics
- (2015) Takashi Watanabe et al. CELL STRUCTURE AND FUNCTION
- The biology of IQGAP proteins: beyond the cytoskeleton
- (2015) A. C. Hedman et al. EMBO REPORTS
- IQGAP1 Is Involved in Enhanced Aggressive Behavior of Epithelial Ovarian Cancer Stem Cell-Like Cells During Differentiation
- (2015) Lu Huang et al. INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
- miR-506 regulates breast cancer cell metastasis by targeting IQGAP1
- (2015) GUANG SUN et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- IQGAP1 controls tight junction formation through differential regulation of claudin recruitment
- (2015) B. E. Tanos et al. JOURNAL OF CELL SCIENCE
- IQGAP1 and IQGAP3 Serve Individually Essential Roles in Normal Epidermal Homeostasis and Tumor Progression
- (2015) Christine L. Monteleon et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- IQGAP1: Insights into the function of a molecular puppeteer
- (2015) Alex M. Abel et al. MOLECULAR IMMUNOLOGY
- Targeting the PI3K/AKT/mTOR pathway in squamous cell carcinoma of the head and neck
- (2015) Daniel R. Simpson et al. ORAL ONCOLOGY
- IQGAPs choreograph cellular signaling from the membrane to the nucleus
- (2015) Jessica M. Smith et al. TRENDS IN CELL BIOLOGY
- Macrophages and cancer: from mechanisms to therapeutic implications
- (2015) Renato Ostuni et al. TRENDS IN IMMUNOLOGY
- Transforming growth factor-β inhibits IQ motif containing guanosine triphosphatase activating protein 1 expression in lung fibroblasts via the nuclear factor-κB signaling pathway
- (2015) CHUANYUE ZONG et al. Molecular Medicine Reports
- The Overexpression of IQGAP1 and β-Catenin Is Associated with Tumor Progression in Hepatocellular Carcinoma In Vitro and In Vivo
- (2015) Xuewen Jin et al. PLoS One
- The mutational spectrum of squamous-cell carcinoma of the head and neck: targetable genetic events and clinical impact
- (2014) G. Mountzios et al. ANNALS OF ONCOLOGY
- Differential Expression of IQGAP1/2 in Hepatocellular Carcinoma and its Relationship with Clinical Outcomes
- (2014) Fa-Da Xia et al. Asian Pacific Journal of Cancer Prevention
- IQGAP1 selectively interacts with K-Ras but not with H-Ras and modulates K-Ras function
- (2014) Hironori Matsunaga et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The MAPK pathway across different malignancies: A new perspective
- (2014) Mauricio Burotto et al. CANCER
- An increase in integrin-linked kinase non-canonically confers NF-κB-mediated growth advantages to gastric cancer cells by activating ERK1/2
- (2014) Po-Chun Tseng et al. Cell Communication and Signaling
- Gemcitabine: Metabolism and molecular mechanisms of action, sensitivity and chemoresistance in pancreatic cancer
- (2014) Lucas de Sousa Cavalcante et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- The role of the cytoskeleton at the immunological synapse
- (2014) Alex T. Ritter et al. IMMUNOLOGICAL REVIEWS
- IQGAP1 Binds to Estrogen Receptor-α and Modulates Its Function
- (2014) Huseyin H. Erdemir et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Overexpression of DNAJB6 promotes colorectal cancer cell invasion through an IQGAP1/ERK-dependent signaling pathway
- (2014) Tong-Tong Zhang et al. MOLECULAR CARCINOGENESIS
- Aberrant RSPO3-LGR4 signaling in Keap1-deficient lung adenocarcinomas promotes tumor aggressiveness
- (2014) X Gong et al. ONCOGENE
- IQGAP3 Promotes EGFR-ERK Signaling and the Growth and Metastasis of Lung Cancer Cells
- (2014) Ying Yang et al. PLoS One
- Targeted Knockdown of IQGAP1 Inhibits the Progression of Esophageal Squamous Cell Carcinoma In Vitro and In Vivo
- (2014) Xiao-Xia Wang et al. PLoS One
- Coexpression of IQ-Domain GTPase-Activating Protein 1 (IQGAP1) and Dishevelled (Dvl) Is Correlated with Poor Prognosis in Non-Small Cell Lung Cancer
- (2014) Huanyu Zhao et al. PLoS One
- RSPO–LGR4 functions via IQGAP1 to potentiate Wnt signaling
- (2014) Kendra S. Carmon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- KRAS: feeding pancreatic cancer proliferation
- (2014) Kirsten L. Bryant et al. TRENDS IN BIOCHEMICAL SCIENCES
- IQGAP1 Is Important for Activation of Caspase-1 in Macrophages and Is Targeted by Yersinia pestis Type III Effector YopM
- (2014) L. K. Chung et al. mBio
- A PAK6–IQGAP1 complex promotes disassembly of cell–cell adhesions
- (2013) Sally Fram et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- IQGAP1 is a novel phosphatidylinositol 4,5 bisphosphate effector in regulation of directional cell migration
- (2013) Suyong Choi et al. EMBO JOURNAL
- KISS1R Induces Invasiveness of Estrogen Receptor-Negative Human Mammary Epithelial and Breast Cancer Cells
- (2013) Donna Cvetković et al. ENDOCRINOLOGY
- Overexpression of IQGAP1 in human pancreatic cancer
- (2013) Xiao-Xia Wang et al. Hepatobiliary & Pancreatic Diseases International
- IQGAP1 Protein Regulates Nuclear Localization of β-Catenin via Importin-β5 Protein in Wnt Signaling
- (2013) Toshiyasu Goto et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- RCP-driven α5β1 recycling suppresses Rac and promotes RhoA activity via the RacGAP1–IQGAP1 complex
- (2013) Guillaume Jacquemet et al. JOURNAL OF CELL BIOLOGY
- IQGAP1 suppresses TβRII-mediated myofibroblastic activation and metastatic growth in liver
- (2013) Chunsheng Liu et al. JOURNAL OF CLINICAL INVESTIGATION
- IQGAP1 scaffold-kinase interaction blockade selectively targets RAS-MAP kinase–driven tumors
- (2013) Katherine L Jameson et al. NATURE MEDICINE
- β-Arrestin2 Regulates Lysophosphatidic Acid-Induced Human Breast Tumor Cell Migration and Invasion via Rap1 and IQGAP1
- (2013) Mistre Alemayehu et al. PLoS One
- IQGAP1 Functions as a Modulator of Dishevelled Nuclear Localization in Wnt Signaling
- (2013) Toshiyasu Goto et al. PLoS One
- Frequent Mutation of the PI3K Pathway in Head and Neck Cancer Defines Predictive Biomarkers
- (2013) V. W. Y. Lui et al. Cancer Discovery
- Bile Acids Activate YAP to Promote Liver Carcinogenesis
- (2013) Sayeepriyadarshini Anakk et al. Cell Reports
- DGKζ is involved in LPS-activated phagocytosis through IQGAP1/Rac1 pathway
- (2012) Masashi Okada et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Cell polarisation and the immunological synapse
- (2012) Karen L Angus et al. CURRENT OPINION IN CELL BIOLOGY
- The Cytoskeletal Adaptor Protein IQGAP1 Regulates TCR-Mediated Signaling and Filamentous Actin Dynamics
- (2012) J. A. Gorman et al. JOURNAL OF IMMUNOLOGY
- Cellular Entry of Human Papillomavirus Type 16 Involves Activation of the Phosphatidylinositol 3-Kinase/Akt/mTOR Pathway and Inhibition of Autophagy
- (2012) Z. Surviladze et al. JOURNAL OF VIROLOGY
- RhoC Regulates the Proliferation of Gastric Cancer Cells through Interaction with IQGAP1
- (2012) Yan Wu et al. PLoS One
- IQGAP1 and its binding proteins control diverse biological functions
- (2011) Colin D. White et al. CELLULAR SIGNALLING
- IQGAP1 involvement in MTOC and granule polarization in NK-cell cytotoxicity
- (2011) Namita Kanwar et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- MAPK Scaffold IQGAP1 Binds the EGF Receptor and Modulates Its Activation
- (2011) Dean E. McNulty et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- IQGAP1 Protein Binds Human Epidermal Growth Factor Receptor 2 (HER2) and Modulates Trastuzumab Resistance
- (2011) Colin D. White et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- RhoC protein stimulates migration of gastric cancer cells through interaction with scaffold protein IQGAP1
- (2011) Yong-Chang Chen Molecular Medicine Reports
- IQGAP1 Is a Novel CXCR2-Interacting Protein and Essential Component of the “Chemosynapse”
- (2011) Nicole F. Neel et al. PLoS One
- Dephosphorylation of the nuclear factor of activated T cells (NFAT) transcription factor is regulated by an RNA-protein scaffold complex
- (2011) S. Sharma et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- IQGAP1 and IQGAP2 are Reciprocally Altered in Hepatocellular Carcinoma
- (2010) Colin D White et al. BMC GASTROENTEROLOGY
- The HPV16 E6 binding protein Tip-1 interacts with ARHGEF16, which activates Cdc42
- (2010) A W Oliver et al. BRITISH JOURNAL OF CANCER
- Rapamycin Inhibits Anal Carcinogenesis in Two Preclinical Animal Models
- (2010) M. K. Stelzer et al. Cancer Prevention Research
- IQGAP1 is overexpressed in hepatocellular carcinoma and promotes cell proliferation by Akt activation
- (2010) Feng Chen et al. EXPERIMENTAL AND MOLECULAR MEDICINE
- Rap1b facilitates NK cell functions via IQGAP1-mediated signalosomes
- (2010) Aradhana Awasthi et al. JOURNAL OF EXPERIMENTAL MEDICINE
- HPV-associated head and neck cancer: a virus-related cancer epidemic
- (2010) Shanthi Marur et al. LANCET ONCOLOGY
- IQGAP1 Is Involved in Post-Ischemic Neovascularization by Regulating Angiogenesis and Macrophage Infiltration
- (2010) Norifumi Urao et al. PLoS One
- Mediation of T-Cell Activation by Actin Meshworks
- (2010) P. Beemiller et al. Cold Spring Harbor Perspectives in Biology
- miR-124 and miR-203 are epigenetically silenced tumor-suppressive microRNAs in hepatocellular carcinoma
- (2009) Mayuko Furuta et al. CARCINOGENESIS
- Rac1 activation inhibits E-cadherin-mediated adherens junctions via binding to IQGAP1 in pancreatic carcinoma cells
- (2009) Beatrix Hage et al. Cell Communication and Signaling
- IQGAP1 regulation and roles in cancer
- (2009) Michael Johnson et al. CELLULAR SIGNALLING
- IQGAPs in cancer: A family of scaffold proteins underlying tumorigenesis
- (2009) Colin D. White et al. FEBS LETTERS
- Overexpression of IQGAP1 in advanced colorectal cancer correlates with poor prognosis-critical role in tumor invasion
- (2009) Hiroyuki Hayashi et al. INTERNATIONAL JOURNAL OF CANCER
- Phosphorylation of CLASP2 by GSK-3 regulates its interaction with IQGAP1, EB1 and microtubules
- (2009) T. Watanabe et al. JOURNAL OF CELL SCIENCE
- Quantitative Proteomic Analysis of HepG2 Cells Treated with Quercetin Suggests IQGAP1 Involved in Quercetin-Induced Regulation of Cell Proliferation and Migration
- (2009) Jin Zhou et al. OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY
- TGFβ in Cancer
- (2008) Joan Massagué CELL
- Proteomic Analysis of Laser-Captured Paraffin-Embedded Tissues: A Molecular Portrait of Head and Neck Cancer Progression
- (2008) V. Patel et al. CLINICAL CANCER RESEARCH
- IQGAP1 activates Tcf signal independent of Rac1 and Cdc42 in injury and repair of bronchial epithelial cells
- (2008) Yongping Wang et al. EXPERIMENTAL AND MOLECULAR PATHOLOGY
- The interaction of IQGAP1 with the exocyst complex is required for tumor cell invasion downstream of Cdc42 and RhoA
- (2008) Mika Sakurai-Yageta et al. JOURNAL OF CELL BIOLOGY
- Silencing of IQGAP1 by shRNA inhibits the invasion of ovarian carcinoma HO-8910PM cells in vitro
- (2008) Pei-Xin Dong et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Combined analysis of Rac1, IQGAP1, Tiam1 and E-cadherin expression in gastric cancer
- (2008) Axel Walch et al. MODERN PATHOLOGY
- Development of Hepatocellular Carcinoma in Iqgap2-Deficient Mice Is IQGAP1 Dependent
- (2008) V. A. Schmidt et al. MOLECULAR AND CELLULAR BIOLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started