Transforming Growth Factor-β (TGF-β) Directly Activates the JAK1-STAT3 Axis to Induce Hepatic Fibrosis in Coordination with the SMAD Pathway

TGF-β signalling and liver disease

(2016) Isabel Fabregat et al.   FEBS Journal

TGF-β Signaling from Receptors to Smads

(2016) Akiko Hata et al.   Cold Spring Harbor Perspectives in Biology

Non-Smad Signaling Pathways of the TGF-β Family

(2016) Ying E. Zhang   Cold Spring Harbor Perspectives in Biology

TGF-β and the TGF-β Family: Context-Dependent Roles in Cell and Tissue Physiology

(2016) Masato Morikawa et al.   Cold Spring Harbor Perspectives in Biology

STAT3 selectively interacts with Smad3 to antagonize TGF-β

(2015) G Wang et al.   ONCOGENE

Phosphorylation status determines the opposing functions of Smad2/Smad3 as STAT3 cofactors in TH17 differentiation

(2015) Jeong-Hwan Yoon et al.   Nature Communications

Stat3 signaling activation crosslinking of TGF-β1 in hepatic stellate cell exacerbates liver injury and fibrosis

(2014) Ming-Yi Xu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Transforming Growth Factor-β (TGF-β)-mediated Connective Tissue Growth Factor (CTGF) Expression in Hepatic Stellate Cells Requires Stat3 Signaling Activation

(2013) Yan Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The CRAPome: a contaminant repository for affinity purification–mass spectrometry data

(2013) Dattatreya Mellacheruvu et al.   NATURE METHODS

Interleukin-17 Signaling in Inflammatory, Kupffer Cells, and Hepatic Stellate Cells Exacerbates Liver Fibrosis in Mice

(2012) Fanli Meng et al.   GASTROENTEROLOGY

Signal Transducer and Activator of Transcription 3 in Liver Diseases: A Novel Therapeutic Target

(2012) Hua Wang et al.   International Journal of Biological Sciences

The JAK/STAT Pathway

(2012) D. A. Harrison   Cold Spring Harbor Perspectives in Biology

Signal Transducer and Activator of Transcription 3 Protects From Liver Injury and Fibrosis in a Mouse Model of Sclerosing Cholangitis

(2010) Markus Mair et al.   GASTROENTEROLOGY

Lack of interleukin-6/glycoprotein 130/signal transducers and activators of transcription-3 signaling in hepatocytes predisposes to liver steatosis and injury in mice

(2009) Daniela C. Kroy et al.   HEPATOLOGY

A Negative Feedback Control of Transforming Growth Factor-β Signaling by Glycogen Synthase Kinase 3-mediated Smad3 Linker Phosphorylation at Ser-204

(2009) Caroline Millet et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

BlobFinder, a tool for fluorescence microscopy image cytometry

(2008) A. Allalou et al.   COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE

TRAF6 Mediates Smad-Independent Activation of JNK and p38 by TGF-β

(2008) Motozo Yamashita et al.   MOLECULAR CELL

The type I TGF-β receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner

(2008) Alessandro Sorrentino et al.   NATURE CELL BIOLOGY

Progenitor/stem cells give rise to liver cancer due to aberrant TGF-  and IL-6 signaling

(2008) Y. Tang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA