Single-cell image analysis to explore cell-to-cell heterogeneity in isogenic populations
出版年份 2021 全文链接
标题
Single-cell image analysis to explore cell-to-cell heterogeneity in isogenic populations
作者
关键词
single-cell image analysis, phenotypic diversity, phenotypic heterogeneity, high-content screening, fluorescence microscopy
出版物
Cell Systems
Volume 12, Issue 6, Pages 608-621
出版商
Elsevier BV
发表日期
2021-06-16
DOI
10.1016/j.cels.2021.05.010
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Image-based pooled whole-genome CRISPRi screening for subcellular phenotypes
- (2021) Gil Kanfer et al. JOURNAL OF CELL BIOLOGY
- DeepCell Kiosk: scaling deep learning–enabled cellular image analysis with Kubernetes
- (2021) Dylan Bannon et al. NATURE METHODS
- Spatiotemporal dissection of the cell cycle with single-cell proteogenomics
- (2021) Diana Mahdessian et al. NATURE
- Imaging cell lineage with a synthetic digital recording system
- (2021) Ke-Huan K. Chow et al. SCIENCE
- Systematic genetics and single‐cell imaging reveal widespread morphological pleiotropy and cell‐to‐cell variability
- (2020) Mojca Mattiazzi Usaj et al. Molecular Systems Biology
- HSF1 phase transition mediates stress adaptation and cell fate decisions
- (2020) Giorgio Gaglia et al. NATURE CELL BIOLOGY
- A genome-wide approach for identification and characterisation of metabolite-inducible systems
- (2020) Erik K. R. Hanko et al. Nature Communications
- Single cell analysis reveals multiple requirements for zinc in the mammalian cell cycle
- (2020) Maria N Lo et al. eLife
- Single-Cell Tracing Dissects Regulation of Maintenance and Inheritance of Transcriptional Reinduction Memory
- (2020) Poonam Bheda et al. MOLECULAR CELL
- Temporal integration of mitogen history in mother cells controls proliferation of daughter cells
- (2020) Mingwei Min et al. SCIENCE
- DeLTA: Automated cell segmentation, tracking, and lineage reconstruction using deep learning
- (2020) Jean-Baptiste Lugagne et al. PLoS Computational Biology
- High‐throughput, microscope‐based sorting to dissect cellular heterogeneity
- (2020) Nicholas Hasle et al. Molecular Systems Biology
- Single-cell multiomics: technologies and data analysis methods
- (2020) Jeongwoo Lee et al. EXPERIMENTAL AND MOLECULAR MEDICINE
- A physicochemical perspective of aging from single-cell analysis of pH, macromolecular and organellar crowding in yeast
- (2020) Sara N Mouton et al. eLife
- Divergent Aging of Isogenic Yeast Cells Revealed through Single-Cell Phenotypic Dynamics
- (2019) Meng Jin et al. Cell Systems
- Escalating Threat Levels of Bacterial Infection Can Be Discriminated by Distinct MAPK and NF-κB Signaling Dynamics in Single Host Cells
- (2019) Keara Lane et al. Cell Systems
- Transcriptome-scale super-resolved imaging in tissues by RNA seqFISH+
- (2019) Chee-Huat Linus Eng et al. NATURE
- Self-organization and symmetry breaking in intestinal organoid development
- (2019) Denise Serra et al. NATURE
- Deep learning for cellular image analysis
- (2019) Erick Moen et al. NATURE METHODS
- The next generation of CRISPR–Cas technologies and applications
- (2019) Adrian Pickar-Oliver et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Evaluation of Deep Learning Strategies for Nucleus Segmentation in Fluorescence Images
- (2019) Juan C. Caicedo et al. CYTOMETRY PART A
- Age-dependent deterioration of nuclear pore assembly in mitotic cells decreases transport dynamics
- (2019) Irina L Rempel et al. eLife
- Spatial transcriptome profiling by MERFISH reveals subcellular RNA compartmentalization and cell cycle-dependent gene expression
- (2019) Chenglong Xia et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Learning unsupervised feature representations for single cell microscopy images with paired cell inpainting
- (2019) Alex X. Lu et al. PLoS Computational Biology
- Optical Pooled Screens in Human Cells
- (2019) David Feldman et al. CELL
- In situ readout of DNA barcodes and single base edits facilitated by in vitro transcription
- (2019) Amjad Askary et al. NATURE BIOTECHNOLOGY
- Analysis of the Human Protein Atlas Image Classification competition
- (2019) Wei Ouyang et al. NATURE METHODS
- Measuring glycolytic flux in single yeast cells with an orthogonal synthetic biosensor
- (2019) Francisca Monteiro et al. Molecular Systems Biology
- In Silico Labeling: Predicting Fluorescent Labels in Unlabeled Images
- (2018) Eric M. Christiansen et al. CELL
- RNA Interference (RNAi) Screening inDrosophila
- (2018) Florian Heigwer et al. GENETICS
- Arrayed CRISPR screen with image-based assay reliably uncovers host genes required for coxsackievirus infection
- (2018) Heon Seok Kim et al. GENOME RESEARCH
- Large‐scale image‐based profiling of single‐cell phenotypes in arrayed CRISPR‐Cas9 gene perturbation screens
- (2018) Reinoud de Groot et al. Molecular Systems Biology
- Three-dimensional intact-tissue sequencing of single-cell transcriptional states
- (2018) Xiao Wang et al. SCIENCE
- Integrating images from multiple microscopy screens reveals diverse patterns of change in the subcellular localization of proteins
- (2018) Alex X Lu et al. eLife
- RNA Interference (RNAi) Screening inDrosophila
- (2018) Florian Heigwer et al. GENETICS
- Rare Cell Detection by Single-Cell RNA Sequencing as Guided by Single-Molecule RNA FISH
- (2018) Eduardo Torre et al. Cell Systems
- Phenotypic Image Analysis Software Tools for Exploring and Understanding Big Image Data from Cell-Based Assays
- (2018) Kevin Smith et al. Cell Systems
- Integration of Multiple Metabolic Signals Determines Cell Fate Prior to Commitment
- (2018) Orlando Argüello-Miranda et al. MOLECULAR CELL
- Deep learning is combined with massive-scale citizen science to improve large-scale image classification
- (2018) Devin P Sullivan et al. NATURE BIOTECHNOLOGY
- Label-free prediction of three-dimensional fluorescence images from transmitted-light microscopy
- (2018) Chawin Ounkomol et al. NATURE METHODS
- Analysis of redox landscapes and dynamics in living cells and in vivo using genetically encoded fluorescent sensors
- (2018) Yejun Zou et al. Nature Protocols
- Multiplexed protein maps link subcellular organization to cellular states
- (2018) Gabriele Gut et al. SCIENCE
- Ki67 is a Graded Rather than a Binary Marker of Proliferation versus Quiescence
- (2018) Iain Miller et al. Cell Reports
- Intrinsic Dynamics of a Human Gene Reveal the Basis of Expression Heterogeneity
- (2018) Joseph Rodriguez et al. CELL
- Replicative aging as a source of cell heterogeneity in budding yeast
- (2018) Dmitry A. Knorre et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Spatial organization of the somatosensory cortex revealed by osmFISH
- (2018) Simone Codeluppi et al. NATURE METHODS
- Real-Time Imaging of Mitochondrial ATP Dynamics Reveals the Metabolic Setting of Single Cells
- (2018) Maria R. Depaoli et al. Cell Reports
- High-content analysis screening for cell cycle regulators using arrayed synthetic crRNA libraries
- (2017) Žaklina Strezoska et al. JOURNAL OF BIOTECHNOLOGY
- Digging deep into Golgi phenotypic diversity with unsupervised machine learning
- (2017) Shaista Hussain et al. MOLECULAR BIOLOGY OF THE CELL
- Systematic gene tagging using CRISPR/Cas9 in human stem cells to illuminate cell organization
- (2017) Brock Roberts et al. MOLECULAR BIOLOGY OF THE CELL
- Genetically Encoded Tools for Optical Dissection of the Mammalian Cell Cycle
- (2017) Asako Sakaue-Sawano et al. MOLECULAR CELL
- Automated analysis of high‐content microscopy data with deep learning
- (2017) Oren Z Kraus et al. Molecular Systems Biology
- Synthetic recording and in situ readout of lineage information in single cells
- (2017) Kirsten L. Frieda et al. NATURE
- Data-analysis strategies for image-based cell profiling
- (2017) Juan C Caicedo et al. NATURE METHODS
- Genetically encoded fluorescent sensors reveal dynamic regulation of NADPH metabolism
- (2017) Rongkun Tao et al. NATURE METHODS
- Profiling the transcriptome with RNA SPOTs
- (2017) Chee-Huat Linus Eng et al. NATURE METHODS
- Image Data Resource: a bioimage data integration and publication platform
- (2017) Eleanor Williams et al. NATURE METHODS
- Multigenerational silencing dynamics control cell aging
- (2017) Yang Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A subcellular map of the human proteome
- (2017) Peter J. Thul et al. SCIENCE
- Quantitative Cell Cycle Analysis Based on an Endogenous All-in-One Reporter for Cell Tracking and Classification
- (2017) Thomas Zerjatke et al. Cell Reports
- Accurate Classification of Protein Subcellular Localization from High-Throughput Microscopy Images Using Deep Learning
- (2017) Tanel Pärnamaa et al. G3-Genes Genomes Genetics
- High-Throughput, High-Resolution Mapping of Protein Localization in Mammalian Brain by In Vivo Genome Editing
- (2016) Takayasu Mikuni et al. CELL
- Machine learning and computer vision approaches for phenotypic profiling
- (2016) Ben T. Grys et al. JOURNAL OF CELL BIOLOGY
- Cell Painting, a high-content image-based assay for morphological profiling using multiplexed fluorescent dyes
- (2016) Mark-Anthony Bray et al. Nature Protocols
- A scalable strategy for high-throughput GFP tagging of endogenous human proteins
- (2016) Manuel D. Leonetti et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- High-throughput single-cell gene-expression profiling with multiplexed error-robust fluorescence in situ hybridization
- (2016) Jeffrey R. Moffitt et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A global genetic interaction network maps a wiring diagram of cellular function
- (2016) M. Costanzo et al. SCIENCE
- Dynamics of epigenetic regulation at the single-cell level
- (2016) L. Bintu et al. SCIENCE
- High-Content Screening for Quantitative Cell Biology
- (2016) Mojca Mattiazzi Usaj et al. TRENDS IN CELL BIOLOGY
- Asymmetric Inheritance of Aggregated Proteins and Age Reset in Yeast Are Regulated by Vac17-Dependent Vacuolar Functions
- (2016) Sandra Malmgren Hill et al. Cell Reports
- Exploring Quantitative Yeast Phenomics with Single-Cell Analysis of DNA Damage Foci
- (2016) Erin B. Styles et al. Cell Systems
- Analysis of Cell Lineage Trees by Exact Bayesian Inference Identifies Negative Autoregulation of Nanog in Mouse Embryonic Stem Cells
- (2016) Justin Feigelman et al. Cell Systems
- Inferring Cell-State Transition Dynamics from Lineage Trees and Endpoint Single-Cell Measurements
- (2016) Sahand Hormoz et al. Cell Systems
- A genome-wide imaging-based screening to identify genes involved in synphilin-1 inclusion formation in Saccharomyces cerevisiae
- (2016) Lei Zhao et al. Scientific Reports
- Yeast Proteome Dynamics from Single Cell Imaging and Automated Analysis
- (2015) Yolanda T. Chong et al. CELL
- Microscopy-Based High-Content Screening
- (2015) Michael Boutros et al. CELL
- SoNar, a Highly Responsive NAD+/NADH Sensor, Allows High-Throughput Metabolic Screening of Anti-tumor Agents
- (2015) Yuzheng Zhao et al. Cell Metabolism
- Single-cell phenomics in budding yeast
- (2015) Yoshikazu Ohya et al. MOLECULAR BIOLOGY OF THE CELL
- Choosing the Right Tool for the Job: RNAi, TALEN, or CRISPR
- (2015) Michael Boettcher et al. MOLECULAR CELL
- A functional perspective on phenotypic heterogeneity in microorganisms
- (2015) Martin Ackermann NATURE REVIEWS MICROBIOLOGY
- A Hierarchical Map of Regulatory Genetic Interactions in Membrane Trafficking
- (2014) Prisca Liberali et al. CELL
- High-Sensitivity Measurements of Multiple Kinase Activities in Live Single Cells
- (2014) Sergi Regot et al. CELL
- A Genomic Multiprocess Survey of Machineries that Control and Link Cell Shape, Microtubule Organization, and Cell-Cycle Progression
- (2014) Veronika Graml et al. DEVELOPMENTAL CELL
- Role of SAGA in the asymmetric segregation of DNA circles during yeast ageing
- (2014) Annina Denoth-Lippuner et al. eLife
- The details in the distributions: why and how to study phenotypic variability
- (2013) KA Geiler-Samerotte et al. CURRENT OPINION IN BIOTECHNOLOGY
- A screen for morphological complexity identifies regulators of switch-like transitions between discrete cell shapes
- (2013) Zheng Yin et al. NATURE CELL BIOLOGY
- Genome-wide single-cell-level screen for protein abundance and localization changes in response to DNA damage in S. cerevisiae
- (2013) Aprotim Mazumder et al. NUCLEIC ACIDS RESEARCH
- A chemostat array enables the spatio-temporal analysis of the yeast proteome
- (2013) N. Denervaud et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Single-cell analysis of population context advances RNAi screening at multiple levels
- (2012) Berend Snijder et al. Molecular Systems Biology
- An early age increase in vacuolar pH limits mitochondrial function and lifespan in yeast
- (2012) Adam L. Hughes et al. NATURE
- Tandem fluorescent protein timers for in vivo analysis of protein dynamics
- (2012) Anton Khmelinskii et al. NATURE BIOTECHNOLOGY
- OMERO: flexible, model-driven data management for experimental biology
- (2012) Chris Allan et al. NATURE METHODS
- Bet Hedging in Yeast by Heterogeneous, Age-Correlated Expression of a Stress Protectant
- (2012) Sasha F. Levy et al. PLOS BIOLOGY
- Systematic exploration of essential yeast gene function with temperature-sensitive mutants
- (2011) Zhijian Li et al. NATURE BIOTECHNOLOGY
- Genomic Screening with RNAi: Results and Challenges
- (2010) Stephanie Mohr et al. Annual Review of Biochemistry
- Metadata matters: access to image data in the real world
- (2010) Melissa Linkert et al. JOURNAL OF CELL BIOLOGY
- Integrating high-throughput genetic interaction mapping and high-content screening to explore yeast spindle morphogenesis
- (2010) Franco J. Vizeacoumar et al. JOURNAL OF CELL BIOLOGY
- Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes
- (2010) Beate Neumann et al. NATURE
- Population context determines cell-to-cell variability in endocytosis and virus infection
- (2009) Berend Snijder et al. NATURE
- Replicative Aging in Yeast: The Means to the End
- (2008) K.A. Steinkraus et al. Annual Review of Cell and Developmental Biology
- Visualizing Spatiotemporal Dynamics of Multicellular Cell-Cycle Progression
- (2008) Asako Sakaue-Sawano et al. CELL
- Stochastic switching as a survival strategy in fluctuating environments
- (2008) Murat Acar et al. NATURE GENETICS
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started