Analysis of redox landscapes and dynamics in living cells and in vivo using genetically encoded fluorescent sensors

Visualization of Nicotine Adenine Dinucleotide Redox Homeostasis with Genetically Encoded Fluorescent Sensors

(2018) Yuzheng Zhao et al.   ANTIOXIDANTS & REDOX SIGNALING

Genetically encoded fluorescent sensors reveal dynamic regulation of NADPH metabolism

(2017) Rongkun Tao et al.   NATURE METHODS

Illuminating redox biology using NADH- and NADPH-specific sensors

(2017) Andreas Wiederkehr et al.   NATURE METHODS

Development of redox-sensitive red fluorescent proteins for imaging redox dynamics in cellular compartments

(2016) Yichong Fan et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Real-time and high-throughput analysis of mitochondrial metabolic states in living cells using genetically encoded NAD+/NADH sensors

(2016) Yuzheng Zhao et al.   FREE RADICAL BIOLOGY AND MEDICINE

Real-time monitoring of basal H2O2 levels with peroxiredoxin-based probes

(2016) Bruce Morgan et al.   Nature Chemical Biology

Apollo-NADP+: a spectrally tunable family of genetically encoded sensors for NADP+

(2016) William D Cameron et al.   NATURE METHODS

In vivo monitoring of cellular energy metabolism using SoNar, a highly responsive sensor for NAD+/NADH redox state

(2016) Yuzheng Zhao et al.   Nature Protocols

Biosensor reveals multiple sources for mitochondrial NAD+

(2016) X. A. Cambronne et al.   SCIENCE

Monitoring Redox Dynamics in Living Cells with a Redox-Sensitive Red Fluorescent Protein

(2015) Yichong Fan et al.   ANALYTICAL CHEMISTRY

An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate Synthesis

(2015) Kıvanç Birsoy et al.   CELL

SoNar, a Highly Responsive NAD+/NADH Sensor, Allows High-Throughput Metabolic Screening of Anti-tumor Agents

(2015) Yuzheng Zhao et al.   Cell Metabolism

Profiling metabolic states with genetically encoded fluorescent biosensors for NADH

(2015) Yuzheng Zhao et al.   CURRENT OPINION IN BIOTECHNOLOGY

Tracing Compartmentalized NADPH Metabolism in the Cytosol and Mitochondria of Mammalian Cells

(2014) Caroline A. Lewis et al.   MOLECULAR CELL

Localization of NADPH Production: A Wheel within a Wheel

(2014) Oliver D.K. Maddocks et al.   MOLECULAR CELL

Metabolism of stromal and immune cells in health and disease

(2014) Bart Ghesquière et al.   NATURE

Quantitative flux analysis reveals folate-dependent NADPH production

(2014) Jing Fan et al.   NATURE

Separating NADH and NADPH fluorescence in live cells and tissues using FLIM

(2014) Thomas S. Blacker et al.   Nature Communications

Red fluorescent genetically encoded indicator for intracellular hydrogen peroxide

(2014) Yulia G. Ermakova et al.   Nature Communications

Genetically encoded fluorescent indicator for imaging NAD+/NADH ratio changes in different cellular compartments

(2013) Dmitry S. Bilan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Modulation of oxidative stress as an anticancer strategy

(2013) Chiara Gorrini et al.   NATURE REVIEWS DRUG DISCOVERY

Quantitative metabolic imaging using endogenous fluorescence to detect stem cell differentiation

(2013) Kyle P. Quinn et al.   Scientific Reports

HyPer-3: A Genetically Encoded H2O2 Probe with Improved Performance for Ratiometric and Fluorescence Lifetime Imaging

(2012) Dmitry S. Bilan et al.   ACS Chemical Biology

Pigment Pattern Formation by Contact-Dependent Depolarization

(2012) M. Inaba et al.   SCIENCE

Identification and characterization of a human mitochondrial NAD kinase

(2012) Kazuto Ohashi et al.   Nature Communications

Imaging Cytosolic NADH-NAD+ Redox State with a Genetically Encoded Fluorescent Biosensor

(2011) Yin Pun Hung et al.   Cell Metabolism

Genetically Encoded Fluorescent Sensors for Intracellular NADH Detection

(2011) Yuzheng Zhao et al.   Cell Metabolism

In Vivo Mapping of Hydrogen Peroxide and Oxidized Glutathione Reveals Chemical and Regional Specificity of Redox Homeostasis

(2011) Simone C. Albrecht et al.   Cell Metabolism

Unraveling the Biological Roles of Reactive Oxygen Species

(2011) Michael P. Murphy et al.   Cell Metabolism

A genetically encoded sensor for H2O2 with expanded dynamic range

(2010) Kseniya N. Markvicheva et al.   BIOORGANIC & MEDICINAL CHEMISTRY

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

(2009) Carles Cantó et al.   NATURE

Development of a Family of Redox-Sensitive Green Fluorescent Protein Indicators for Use in Relatively Oxidizing Subcellular Environments†‡

(2008) Jeremy R. Lohman et al.   BIOCHEMISTRY

Real-time imaging of the intracellular glutathione redox potential

(2008) Marcus Gutscher et al.   NATURE METHODS

NAD+/NADH and NADP+/NADPH in Cellular Functions and Cell Death: Regulation and Biological Consequences

(2007) Weihai Ying   ANTIOXIDANTS & REDOX SIGNALING