Arrayed CRISPR screen with image-based assay reliably uncovers host genes required for coxsackievirus infection

CRISPR/Cas9-mediated gene knockout screens and target identification via whole-genome sequencing uncover host genes required for picornavirus infection

(2017) Heon Seok Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

High-content analysis screening for cell cycle regulators using arrayed synthetic crRNA libraries

(2017) Žaklina Strezoska et al.   JOURNAL OF BIOTECHNOLOGY

PLA2G16 represents a switch between entry and clearance of Picornaviridae

(2017) Jacqueline Staring et al.   NATURE

Pooled CRISPR screening with single-cell transcriptome readout

(2017) Paul Datlinger et al.   NATURE METHODS

The Molecular Basis of Aichi Virus 3A Protein Activation of Phosphatidylinositol 4 Kinase IIIβ, PI4KB, through ACBD3

(2017) Jacob A. McPhail et al.   STRUCTURE

The Golgi protein ACBD3 facilitates Enterovirus 71 replication by interacting with 3A

(2017) Xiaobo Lei et al.   Scientific Reports

Enhancing the genome editing toolbox: genome wide CRISPR arrayed libraries

(2017) Emmanouil Metzakopian et al.   Scientific Reports

Dissecting Immune Circuits by Linking CRISPR-Pooled Screens with Single-Cell RNA-Seq

(2016) Diego Adhemar Jaitin et al.   CELL

Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic Screens

(2016) Atray Dixit et al.   CELL

CCAT1 is an enhancer-templated RNA that predicts BET sensitivity in colorectal cancer

(2016) Mark L. McCleland et al.   JOURNAL OF CLINICAL INVESTIGATION

A CRISPR screen defines a signal peptide processing pathway required by flaviviruses

(2016) Rong Zhang et al.   NATURE

Genetic dissection of Flaviviridae host factors through genome-scale CRISPR screens

(2016) Caleb D. Marceau et al.   NATURE

A genome-wide CRISPR screen identifies a restricted set of HIV host dependency factors

(2016) Ryan J Park et al.   NATURE GENETICS

Validation of Synthetic CRISPR Reagents as a Tool for Arrayed Functional Genomic Screening

(2016) Jenille Tan et al.   PLoS One

A Cas9 Ribonucleoprotein Platform for Functional Genetic Studies of HIV-Host Interactions in Primary Human T Cells

(2016) Judd F. Hultquist et al.   Cell Reports

Identification of Zika Virus and Dengue Virus Dependency Factors using Functional Genomics

(2016) George Savidis et al.   Cell Reports

Synergistic antiviral activity of gemcitabine and ribavirin against enteroviruses

(2015) Hyunju Kang et al.   ANTIVIRAL RESEARCH

Digenome-seq: genome-wide profiling of CRISPR-Cas9 off-target effects in human cells

(2015) Daesik Kim et al.   NATURE METHODS

Gene essentiality and synthetic lethality in haploid human cells

(2015) V. A. Blomen et al.   SCIENCE

A CRISPR-Based Screen Identifies Genes Essential for West-Nile-Virus-Induced Cell Death

(2015) Hongming Ma et al.   Cell Reports

Itraconazole Inhibits Enterovirus Replication by Targeting the Oxysterol-Binding Protein

(2015) Jeroen R.P.M. Strating et al.   Cell Reports

Cas-OFFinder: a fast and versatile algorithm that searches for potential off-target sites of Cas9 RNA-guided endonucleases

(2014) S. Bae et al.   BIOINFORMATICS

RACK1 Controls IRES-Mediated Translation of Viruses

(2014) Karim Majzoub et al.   CELL

Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation

(2014) Luke A. Gilbert et al.   CELL

Rhinovirus Uses a Phosphatidylinositol 4-Phosphate/Cholesterol Counter-Current for the Formation of Replication Compartments at the ER-Golgi Interface

(2014) Pascal S. Roulin et al.   Cell Host & Microbe

Recruitment of Phosphatase PP2A by RACK1 Adaptor Protein Deactivates Transcription Factor IRF3 and Limits Type I Interferon Signaling

(2014) Lingyun Long et al.   IMMUNITY

Improving CRISPR-Cas nuclease specificity using truncated guide RNAs

(2014) Yanfang Fu et al.   NATURE BIOTECHNOLOGY

Microhomology-based choice of Cas9 nuclease target sites

(2014) Sangsu Bae et al.   NATURE METHODS

Improved vectors and genome-wide libraries for CRISPR screening

(2014) Neville E Sanjana et al.   NATURE METHODS

Genome-Wide RNAi Screen Identifies Broadly-Acting Host Factors That Inhibit Arbovirus Infection

(2014) Ari Yasunaga et al.   PLoS Pathogens

A Four-Step Cycle Driven by PI(4)P Hydrolysis Directs Sterol/PI(4)P Exchange by the ER-Golgi Tether OSBP

(2013) Bruno Mesmin et al.   CELL

Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases

(2013) S. W. Cho et al.   GENOME RESEARCH

The Golgi Protein ACBD3, an Interactor for Poliovirus Protein 3A, Modulates Poliovirus Replication

(2013) F. Teoule et al.   JOURNAL OF VIROLOGY

Recruitment of PI4KIII  to Coxsackievirus B3 Replication Organelles Is Independent of ACBD3, GBF1, and Arf1

(2013) C. M. Dorobantu et al.   JOURNAL OF VIROLOGY

Genome-wide recessive genetic screening in mammalian cells with a lentiviral CRISPR-guide RNA library

(2013) Hiroko Koike-Yusa et al.   NATURE BIOTECHNOLOGY

Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells

(2013) Ophir Shalem et al.   SCIENCE

Genetic Screens in Human Cells Using the CRISPR-Cas9 System

(2013) Tim Wang et al.   SCIENCE

C911: A Bench-Level Control for Sequence Specific siRNA Off-Target Effects

(2012) Eugen Buehler et al.   PLoS One

Use and Abuse of RNAi to Study Mammalian Gene Function

(2012) W. G. Kaelin   SCIENCE

Inhibition of fatty acid synthase by amentoflavone reduces coxsackievirus B3 replication

(2011) Steffi Wilsky et al.   ARCHIVES OF VIROLOGY

Comparative RNAi Screening Reveals Host Factors Involved in Enterovirus Infection of Polarized Endothelial Monolayers

(2011) Carolyn B. Coyne et al.   Cell Host & Microbe

ACBD3-mediated recruitment of PI4KB to picornavirus RNA replication sites

(2011) Jun Sasaki et al.   EMBO JOURNAL

Foreign Gene Transfer to Cardiomyocyte Using a Replication-Defective Recombinant Coxsackievirus B3 without Cytotoxicity

(2011) Byung-Kwan Lim et al.   INTERVIROLOGY

Viral Reorganization of the Secretory Pathway Generates Distinct Organelles for RNA Replication

(2010) Nai-Yun Hsu et al.   CELL

Acyl-coenzyme A binding domain containing 3 (ACBD3; PAP7; GCP60): An emerging signaling molecule

(2010) Jinjiang Fan et al.   PROGRESS IN LIPID RESEARCH

Dynamin- and Lipid Raft-Dependent Entry of Decay-Accelerating Factor (DAF)-Binding and Non-DAF-Binding Coxsackieviruses into Nonpolarized Cells

(2009) K. P. Patel et al.   JOURNAL OF VIROLOGY

GBF1, a Guanine Nucleotide Exchange Factor for Arf, Is Crucial for Coxsackievirus B3 RNA Replication

(2009) K. H. W. Lanke et al.   JOURNAL OF VIROLOGY

A Morpholino Oligomer Targeting Highly Conserved Internal Ribosome Entry Site Sequence Is Able To Inhibit Multiple Species of Picornavirus

(2008) J. K. Stone et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

RNA-Binding Protein hnRNP D Modulates Internal Ribosome Entry Site-Dependent Translation of Hepatitis C Virus RNA

(2008) K. Y. Paek et al.   JOURNAL OF VIROLOGY