A pan-cancer transcriptomic study showing tumor specific alterations in central metabolism
出版年份 2021 全文链接
标题
A pan-cancer transcriptomic study showing tumor specific alterations in central metabolism
作者
关键词
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出版物
Scientific Reports
Volume 11, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2021-07-01
DOI
10.1038/s41598-021-93003-3
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Bulk and single-cell transcriptome profiling reveal the metabolic heterogeneity in human breast cancers
- (2021) Tian-Jian Yu et al. MOLECULAR THERAPY
- Patient-derived xenografts of different grade gliomas retain the heterogeneous histological and genetic features of human gliomas
- (2020) Wenxin Zeng et al. Cancer Cell International
- Compartmentalized acyl-CoA metabolism and roles in chromatin regulation
- (2020) Sophie Trefely et al. Molecular Metabolism
- Histone Acetylation as a Regenerative Target in the Dentine-Pulp Complex
- (2020) Yukako Yamauchi et al. Frontiers in Genetics
- Clinical Applications and Future Directions of Minimal Residual Disease Testing in Multiple Myeloma
- (2020) Stefania Oliva et al. Frontiers in Oncology
- Dietary modifications for enhanced cancer therapy
- (2020) Naama Kanarek et al. NATURE
- Biochemical and transcript level differences between the three human phosphofructokinases show optimisation of each isoform for specific metabolic niches
- (2020) Peter M. Fernandes et al. BIOCHEMICAL JOURNAL
- In Vivo Evidence for Serine Biosynthesis-Defined Sensitivity of Lung Metastasis, but Not of Primary Breast Tumors, to mTORC1 Inhibition
- (2020) Gianmarco Rinaldi et al. MOLECULAR CELL
- Corrigendum: Blood-Based DNA Methylation Biomarkers for Type 2 Diabetes: Potential for Clinical Applications
- (2019) Tarryn Willmer et al. Frontiers in Endocrinology
- New functionalities in the TCGAbiolinks package for the study and integration of cancer data from GDC and GTEx
- (2019) Mohamed Mounir et al. PLoS Computational Biology
- Fueling the fire: emerging role of the hexosamine biosynthetic pathway in cancer
- (2019) Neha M. Akella et al. BMC BIOLOGY
- Ketogenic diet in the treatment of cancer – Where do we stand?
- (2019) Daniela D. Weber et al. Molecular Metabolism
- New aspects of amino acid metabolism in cancer
- (2019) Lisa Vettore et al. BRITISH JOURNAL OF CANCER
- Oncogenic pathways and the electron transport chain: a dangeROS liaison
- (2019) Vittoria Raimondi et al. BRITISH JOURNAL OF CANCER
- The Pentose Phosphate Pathway as a Potential Target for Cancer Therapy
- (2018) Eunae Sandra Cho et al. Biomolecules & Therapeutics
- A Comprehensive Pan-Cancer Molecular Study of Gynecologic and Breast Cancers
- (2018) Ashton C. Berger et al. CANCER CELL
- Assembly of mammalian oxidative phosphorylation complexes I–V and supercomplexes
- (2018) Alba Signes et al. Essays in Biochemistry
- LDHA upregulation independently predicts poor survival in lung adenocarcinoma, but not in lung squamous cell carcinoma
- (2018) Chengyong Yu et al. Future Oncology
- The carnitine system and cancer metabolic plasticity
- (2018) Mariarosa Anna Beatrice Melone et al. Cell Death & Disease
- Molecular Characterization and Clinical Relevance of Metabolic Expression Subtypes in Human Cancers
- (2018) Xinxin Peng et al. Cell Reports
- Four Key Steps Control Glycolytic Flux in Mammalian Cells
- (2018) Lukas Bahati Tanner et al. Cell Systems
- Oil for the cancer engine: The cross-talk between oncogenic signaling and polyamine metabolism
- (2018) Amaia Arruabarrena-Aristorena et al. Science Advances
- O-GlcNAcylation promotes colorectal cancer metastasis via the miR-101-O-GlcNAc/EZH2 regulatory feedback circuit
- (2018) Mingzuo Jiang et al. ONCOGENE
- Amino acid transporters revisited: New views in health and disease
- (2018) Palanivel Kandasamy et al. TRENDS IN BIOCHEMICAL SCIENCES
- Alcohol Dehydrogenases, Aldehyde Dehydrogenases, and Alcohol Use Disorders: A Critical Review
- (2018) Howard J. Edenberg et al. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH
- Spatially resolved metabolomics to discover tumor-associated metabolic alterations
- (2018) Chenglong Sun et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- UCP2 Overexpression Redirects Glucose into Anabolic Metabolic Pathways
- (2018) Annapoorna Sreedhar et al. PROTEOMICS
- Pan-cancer analysis of transcriptional metabolic dysregulation using The Cancer Genome Atlas
- (2018) S. R. Rosario et al. Nature Communications
- Glutamine Transporters Are Targets of Multiple Oncogenic Signaling Pathways in Prostate Cancer
- (2017) Mark A. White et al. MOLECULAR CANCER RESEARCH
- Glucose feeds the TCA cycle via circulating lactate
- (2017) Sheng Hui et al. NATURE
- Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients
- (2017) Ahmet Zehir et al. NATURE MEDICINE
- Clarifying the supercomplex: the higher-order organization of the mitochondrial electron transport chain
- (2017) James A Letts et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Structural Insight into the Core of CAD, the Multifunctional Protein Leading De Novo Pyrimidine Biosynthesis
- (2017) María Moreno-Morcillo et al. STRUCTURE
- Functional Properties of the Mitochondrial Carrier System
- (2017) Eric B. Taylor TRENDS IN CELL BIOLOGY
- Deactivating Fatty Acids: Acyl-CoA Thioesterase-Mediated Control of Lipid Metabolism
- (2017) Veronika Tillander et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Overexpression and proliferation dependence of acyl-CoA thioesterase 11 and 13 in lung adenocarcinoma
- (2017) Jen-Yu Hung et al. Oncology Letters
- Comprehensive analysis of normal adjacent to tumor transcriptomes
- (2017) Dvir Aran et al. Nature Communications
- Inhibiting the system xC−/glutathione axis selectively targets cancers with mutant-p53 accumulation
- (2017) David S. Liu et al. Nature Communications
- Clarifying the supercomplex: the higher-order organization of the mitochondrial electron transport chain
- (2017) James A Letts et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- HMGCS2 enhances invasion and metastasis via direct interaction with PPARα to activate Src signaling in colorectal cancer and oral cancer
- (2017) Shih-Wen Chen et al. Oncotarget
- Cerebral Gluconeogenesis and Diseases
- (2017) James Yip et al. Frontiers in Pharmacology
- The Leloir Pathway of Galactose Metabolism – A Novel Therapeutic Target for Hepatocellular Carcinoma
- (2016) MANSHU TANG et al. ANTICANCER RESEARCH
- High expression of hexokinase domain containing 1 is associated with poor prognosis and aggressive phenotype in hepatocarcinoma
- (2016) Zijian Zhang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Liver glucose metabolism in humans
- (2016) M. M. Adeva-Andany et al. BIOSCIENCE REPORTS
- ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition
- (2016) Sebastian Doll et al. Nature Chemical Biology
- Altering the Mitochondrial Fatty Acid Synthesis (mtFASII) Pathway Modulates Cellular Metabolic States and Bioactive Lipid Profiles as Revealed by Metabolomic Profiling
- (2016) Hayley B. Clay et al. PLoS One
- Tissue-specific and convergent metabolic transformation of cancer correlates with metastatic potential and patient survival
- (2016) Edoardo Gaude et al. Nature Communications
- Asparagine promotes cancer cell proliferation through use as an amino acid exchange factor
- (2016) Abigail S. Krall et al. Nature Communications
- Fundamentals of cancer metabolism
- (2016) R. J. DeBerardinis et al. Science Advances
- Ultrastructural Characterization of the Lower Motor System in a Mouse Model of Krabbe Disease
- (2016) Valentina Cappello et al. Scientific Reports
- Loss of Mitochondrial Pyruvate Carrier 2 in the Liver Leads to Defects in Gluconeogenesis and Compensation via Pyruvate-Alanine Cycling
- (2015) Kyle S. McCommis et al. Cell Metabolism
- Pyruvate carboxylase is critical for non–small-cell lung cancer proliferation
- (2015) Katherine Sellers et al. JOURNAL OF CLINICAL INVESTIGATION
- Targeting ASCT2-mediated glutamine uptake blocks prostate cancer growth and tumour development
- (2015) Qian Wang et al. JOURNAL OF PATHOLOGY
- Metabolic pathways promoting cancer cell survival and growth
- (2015) Lindsey K. Boroughs et al. NATURE CELL BIOLOGY
- TCGAbiolinks: an R/Bioconductor package for integrative analysis of TCGA data
- (2015) Antonio Colaprico et al. NUCLEIC ACIDS RESEARCH
- Famine versus feast: understanding the metabolism of tumors in vivo
- (2015) Jared R. Mayers et al. TRENDS IN BIOCHEMICAL SCIENCES
- Is Cancer a Genetic Disease or a Metabolic Disease?
- (2015) David S. Wishart EBioMedicine
- Acyl-CoA Metabolism and Partitioning
- (2014) Trisha J. Grevengoed et al. Annual Review of Nutrition
- Proton-associated sucrose transport of mammalian solute carrier family 45: an analysis inSaccharomyces cerevisiae
- (2014) Rabea Bartölke et al. BIOCHEMICAL JOURNAL
- VDAC electronics: 1. VDAC-hexo(gluco)kinase generator of the mitochondrial outer membrane potential
- (2014) Victor V. Lemeshko BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Phosphofructokinase: A mediator of glycolytic flux in cancer progression
- (2014) Nada Al Hasawi et al. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
- Tracing Compartmentalized NADPH Metabolism in the Cytosol and Mitochondria of Mammalian Cells
- (2014) Caroline A. Lewis et al. MOLECULAR CELL
- Regulation of Substrate Utilization by the Mitochondrial Pyruvate Carrier
- (2014) Nathaniel M. Vacanti et al. MOLECULAR CELL
- Quantitative flux analysis reveals folate-dependent NADPH production
- (2014) Jing Fan et al. NATURE
- Ketone body metabolism and cardiovascular disease
- (2013) David G. Cotter et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- The fat side of prostate cancer
- (2013) Giorgia Zadra et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Cellular Fatty Acid Metabolism and Cancer
- (2013) Erin Currie et al. Cell Metabolism
- MYC-driven accumulation of 2-hydroxyglutarate is associated with breast cancer prognosis
- (2013) Atsushi Terunuma et al. JOURNAL OF CLINICAL INVESTIGATION
- The SLC2 (GLUT) family of membrane transporters
- (2013) Mike Mueckler et al. MOLECULAR ASPECTS OF MEDICINE
- Glucose transport families SLC5 and SLC50
- (2013) Ernest M. Wright MOLECULAR ASPECTS OF MEDICINE
- Defects in mitochondrial fatty acid synthesis result in failure of multiple aspects of mitochondrial biogenesis inSaccharomyces cerevisiae
- (2013) V. A. Samuli Kursu et al. MOLECULAR MICROBIOLOGY
- Signatures of mutational processes in human cancer
- (2013) Ludmil B. Alexandrov et al. NATURE
- Heterogeneity of tumor-induced gene expression changes in the human metabolic network
- (2013) Jie Hu et al. NATURE BIOTECHNOLOGY
- The function and the role of the mitochondrial glycerol-3-phosphate dehydrogenase in mammalian tissues
- (2012) Tomáš Mráček et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Glucose-Independent Glutamine Metabolism via TCA Cycling for Proliferation and Survival in B Cells
- (2012) Anne Le et al. Cell Metabolism
- Comprehensive molecular portraits of human breast tumours
- (2012) Daniel C. Koboldt et al. NATURE
- Serine starvation induces stress and p53-dependent metabolic remodelling in cancer cells
- (2012) Oliver D. K. Maddocks et al. NATURE
- A ROS rheostat for cell fate regulation
- (2012) Maria Maryanovich et al. TRENDS IN CELL BIOLOGY
- The role of amino acid transporters in inherited and acquired diseases
- (2011) Stefan Bröer et al. BIOCHEMICAL JOURNAL
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- The monocarboxylate transporter family-Structure and functional characterization
- (2011) Andrew P. Halestrap IUBMB LIFE
- Mitochondrial Carnitine Palmitoyltransferase 1a (CPT1a) Is Part of an Outer Membrane Fatty Acid Transfer Complex
- (2011) Kwangwon Lee et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia
- (2011) Christian M. Metallo et al. NATURE
- Voltage dependent anion channel-1 (VDAC-1) as an anti-cancer target
- (2010) Saroj P. Mathupala et al. CANCER BIOLOGY & THERAPY
- Retinoids regulate stem cell differentiation
- (2010) Lorraine J. Gudas et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Bidirectional Transport of Amino Acids Regulates mTOR and Autophagy
- (2009) Paul Nicklin et al. CELL
- Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
- (2009) M. G. Vander Heiden et al. SCIENCE
- Mitochondrial Fatty Acid Synthesis Type II: More than Just Fatty Acids
- (2008) J. Kalervo Hiltunen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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