Size and surface modification of silica nanoparticles affect the severity of lung toxicity by modulating endosomal ROS generation in macrophages

Repressive role of stabilized hypoxia inducible factor 1α expression on transforming growth factor β‐induced extracellular matrix production in lung cancer cells

(2019) Akira Ando et al.   CANCER SCIENCE

Clarithromycin suppresses induction of monocyte chemoattractant protein-1 and matrix metalloproteinase-9 and improves pathological changes in the lungs and heart of mice infected with influenza A virus

(2018) Etsuhisa Takahashi et al.   COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES

Triggered recruitment of ESCRT machinery promotes endolysosomal repair

(2018) Michael L. Skowyra et al.   SCIENCE

Lysosomal membrane permeabilization and cell death

(2018) Fengjuan Wang et al.   TRAFFIC

The Size and Surface Modification of Amorphous Silica Particles Affect the Biological Processes in Murine Macrophages

(2017) Xiaoyan Lu et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Endosomal NOX2 oxidase exacerbates virus pathogenicity and is a target for antiviral therapy

(2017) Eunice E. To et al.   Nature Communications

SR-B1 Is a Silica Receptor that Mediates Canonical Inflammasome Activation

(2017) Misato Tsugita et al.   Cell Reports

Specific Surface Modifications of Silica Nanoparticles Diminish Inflammasome Activation and In Vivo Expression of Selected Inflammatory Genes

(2017) Viviana Marzaioli et al.   Nanomaterials

Human Scavenger Receptor A1-Mediated Inflammatory Response to Silica Particle Exposure Is Size Specific

(2017) Nobuo Nishijima et al.   Frontiers in Immunology

IL-1β is a key cytokine that induces trypsin upregulation in the influenza virus–cytokine–trypsin cycle

(2016) I. L. Indalao et al.   ARCHIVES OF VIROLOGY

VCP/p97 cooperates with YOD1, UBXD1 and PLAA to drive clearance of ruptured lysosomes by autophagy

(2016) Chrisovalantis Papadopoulos et al.   EMBO JOURNAL

Relationship between size and surface modification of silica particles and enhancement and suppression of inflammatory cytokine production by lipopolysaccharide- or peptidoglycan-stimulated RAW264.7 macrophages

(2016) Eiichiro Uemura et al.   JOURNAL OF NANOPARTICLE RESEARCH

Amine modification of nonporous silica nanoparticles reduces inflammatory response following intratracheal instillation in murine lungs

(2016) Angie S. Morris et al.   TOXICOLOGY LETTERS

Sensitive detection of lysosomal membrane permeabilization by lysosomal galectin puncta assay

(2015) Sonja Aits et al.   Autophagy

Phagocyte NADPH oxidase and specific immunity

(2015) Julien Cachat et al.   CLINICAL SCIENCE

Pro-inflammatory responses of RAW264.7 macrophages when treated with ultralow concentrations of silver, titanium dioxide, and zinc oxide nanoparticles

(2015) Marcella Giovanni et al.   JOURNAL OF HAZARDOUS MATERIALS

Nanotoxicity: An Interplay of Oxidative Stress, Inflammation and Cell Death

(2015) Puja Khanna et al.   Nanomaterials

Surface modifications of silica nanoparticles are crucial for their inert versus proinflammatory and immunomodulatory properties

(2014) Alessandrini et al.   International Journal of Nanomedicine

Adsorption at cell surface and cellular uptake of silica nanoparticles with different surface chemical functionalizations: impact on cytotoxicity

(2014) A. Kurtz-Chalot et al.   JOURNAL OF NANOPARTICLE RESEARCH

Effect of Silica Particle Size on Macrophage Inflammatory Responses

(2014) Toshimasa Kusaka et al.   PLoS One

Autophagy sequesters damaged lysosomes to control lysosomal biogenesis and kidney injury

(2013) Ikuko Maejima et al.   EMBO JOURNAL

Nonporous silica nanoparticles for nanomedicine application

(2013) Li Tang et al.   Nano Today

Differential modulation of surfactant protein D under acute and persistent hypoxia in acute lung injury

(2012) Koji Sakamoto et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Surface modification of amorphous nanosilica particles suppresses nanosilica-induced cytotoxicity, ROS generation, and DNA damage in various mammalian cells

(2012) Tokuyuki Yoshida et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Autophagy and lysosomal dysfunction as emerging mechanisms of nanomaterial toxicity

(2012) Stephan T Stern et al.   Particle and Fibre Toxicology

Impact of Silica Nanoparticle Design on Cellular Toxicity and Hemolytic Activity

(2011) Tian Yu et al.   ACS Nano

The Phagocytosis and Toxicity of Amorphous Silica

(2011) Lindsey M. Costantini et al.   PLoS One

Quantitative Assessment of the Comparative Nanoparticle-Uptake Efficiency of a Range of Cell Lines

(2011) Tiago dos Santos et al.   Small

The effect of surface modification of amorphous silica particles on NLRP3 inflammasome mediated IL-1β production, ROS production and endosomal rupture

(2010) Tomohiro Morishige et al.   BIOMATERIALS

The nanosilica hazard: another variable entity

(2010) Dorota Napierska et al.   Particle and Fibre Toxicology

Size-Dependent Cytotoxicity of Monodisperse Silica Nanoparticles in Human Endothelial Cells

(2009) Dorota Napierska et al.   Small

Signaling Components of Redox Active Endosomes: The Redoxosomes

(2008) Fredrick D. Oakley et al.   ANTIOXIDANTS & REDOX SIGNALING

Endosomal Nox2 Facilitates Redox-Dependent Induction of NF-κB by TNF-α

(2008) Qiang Li et al.   ANTIOXIDANTS & REDOX SIGNALING

Compartmentalization of Redox Signaling Through NADPH Oxidase–Derived ROS

(2008) Masuko Ushio-Fukai   ANTIOXIDANTS & REDOX SIGNALING

Silica binding and toxicity in alveolar macrophages

(2007) Raymond F. Hamilton et al.   FREE RADICAL BIOLOGY AND MEDICINE