Effect of Silica Particle Size on Macrophage Inflammatory Responses

Suppression of nanosilica particle-induced inflammation by surface modification of the particles

(2012) Tomohiro Morishige et al.   ARCHIVES OF TOXICOLOGY

Inhibitory Receptor Paired Ig-like Receptor B Is Exploited by Staphylococcus aureus for Virulence

(2012) M. Nakayama et al.   JOURNAL OF IMMUNOLOGY

Silicosis

(2012) Chi Chiu Leung et al.   LANCET

Amorphous nanosilicas induce consumptive coagulopathy after systemic exposure

(2012) Hiromi Nabeshi et al.   NANOTECHNOLOGY

Amorphous silica nanoparticles size-dependently aggravate atopic dermatitis-like skin lesions following an intradermal injection

(2012) Toshiro Hirai et al.   Particle and Fibre Toxicology

Comparison of non-crystalline silica nanoparticles in IL-1β release from macrophages

(2012) Wiggo J Sandberg et al.   Particle and Fibre Toxicology

Systemic distribution, nuclear entry and cytotoxicity of amorphous nanosilica following topical application

(2011) Hiromi Nabeshi et al.   BIOMATERIALS

Caspase-1-induced pyroptotic cell death

(2011) Edward A. Miao et al.   IMMUNOLOGICAL REVIEWS

Non-canonical inflammasome activation targets caspase-11

(2011) Nobuhiko Kayagaki et al.   NATURE

Amorphous nanosilica induce endocytosis-dependent ROS generation and DNA damage in human keratinocytes

(2011) Hiromi Nabeshi et al.   Particle and Fibre Toxicology

The Phagocytosis and Toxicity of Amorphous Silica

(2011) Lindsey M. Costantini et al.   PLoS One

The effect of surface modification of amorphous silica particles on NLRP3 inflammasome mediated IL-1β production, ROS production and endosomal rupture

(2010) Tomohiro Morishige et al.   BIOMATERIALS

SR-A/MARCO-mediated ligand delivery enhances intracellular TLR and NLR function, but ligand scavenging from cell surface limits TLR4 response to pathogens

(2010) S. Mukhopadhyay et al.   BLOOD

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Nanomaterials and regulation of cosmetics

(2010) Diana M Bowman et al.   Nature Nanotechnology

Molecular mechanisms of necroptosis: an ordered cellular explosion

(2010) Peter Vandenabeele et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Nanoparticles activate the NLR pyrin domain containing 3 (Nlrp3) inflammasome and cause pulmonary inflammation through release of IL-1  and IL-1 

(2010) A. S. Yazdi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Malarial Hemozoin Is a Nalp3 Inflammasome Activating Danger Signal

(2009) Catherine Dostert et al.   PLoS One

Particle size-dependent organ distribution of gold nanoparticles after intravenous administration

(2008) Wim H. De Jong et al.   BIOMATERIALS

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

(2008) Veit Hornung et al.   NATURE IMMUNOLOGY

The Nalp3 inflammasome is essential for the development of silicosis

(2008) Suzanne L. Cassel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica

(2008) C. Dostert et al.   SCIENCE

Macrophage Responses to Silica Nanoparticles are Highly Conserved Across Particle Sizes

(2008) Katrina M. Waters et al.   TOXICOLOGICAL SCIENCES

Transient pulmonary fibrogenic effect induced by intratracheal instillation of ultrafine amorphous silica in A/J mice

(2008) M CHOI et al.   TOXICOLOGY LETTERS