Endosomal NOX2 oxidase exacerbates virus pathogenicity and is a target for antiviral therapy

The receptor TREML4 amplifies TLR7-mediated signaling during antiviral responses and autoimmunity

(2015) Zaida G Ramirez-Ortiz et al.   NATURE IMMUNOLOGY

Reactive Oxygen Species Deficiency Induces Autoimmunity with Type 1 Interferon Signature

(2014) Tiina Kelkka et al.   ANTIOXIDANTS & REDOX SIGNALING

Influenza A virus and TLR7 activation potentiate NOX2 oxidase-dependent ROS production in macrophages

(2014) E. E. To et al.   FREE RADICAL RESEARCH

Endothelin-converting Enzyme 1 and β-Arrestins Exert Spatiotemporal Control of Substance P-induced Inflammatory Signals

(2014) Dane D. Jensen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endocytosis of Viruses and Bacteria

(2014) P. Cossart et al.   Cold Spring Harbor Perspectives in Biology

Essential role for Toll-like receptor 7 (TLR7)-unique cysteines in an intramolecular disulfide bond, proteolytic cleavage and RNA sensing

(2013) Atsuo Kanno et al.   INTERNATIONAL IMMUNOLOGY

Lung T-cell responses to nontypeable Haemophilus influenzae in patients with chronic obstructive pulmonary disease

(2012) Paul T. King et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

NADPH Oxidase Inhibits the Pathogenesis of Systemic Lupus Erythematosus

(2012) A. M. Campbell et al.   Science Translational Medicine

TLR signalling augments macrophage bactericidal activity through mitochondrial ROS

(2011) A. Phillip West et al.   NATURE

Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets

(2011) Grant R. Drummond et al.   NATURE REVIEWS DRUG DISCOVERY

Suppressing production of reactive oxygen species (ROS) for influenza A virus therapy

(2011) Ross Vlahos et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Inhibition of Nox2 Oxidase Activity Ameliorates Influenza A Virus-Induced Lung Inflammation

(2011) Ross Vlahos et al.   PLoS Pathogens

Does Cellular Hydrogen Peroxide Diffuse or Act Locally?

(2010) Natalia M. Mishina et al.   ANTIOXIDANTS & REDOX SIGNALING

Nox enzymes from fungus to fly to fish and what they tell us about Nox function in mammals

(2010) Jesús Aguirre et al.   FREE RADICAL BIOLOGY AND MEDICINE

Direct evidence of a role for Nox2 in superoxide production, reduced nitric oxide bioavailability, and early atherosclerotic plaque formation in ApoE−/− mice

(2009) Courtney P. Judkins et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The NLRP3 Inflammasome Mediates In Vivo Innate Immunity to Influenza A Virus through Recognition of Viral RNA

(2009) Irving C. Allen et al.   IMMUNITY

Inflammasome recognition of influenza virus is essential for adaptive immune responses

(2009) Takeshi Ichinohe et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Identification of Oxidative Stress and Toll-like Receptor 4 Signaling as a Key Pathway of Acute Lung Injury

(2008) Yumiko Imai et al.   CELL

NADPH oxidases in the vasculature: Molecular features, roles in disease and pharmacological inhibition

(2008) Stavros Selemidis et al.   PHARMACOLOGY & THERAPEUTICS

Efficient Inhibition of the Alzheimer's Disease  -Secretase by Membrane Targeting

(2008) L. Rajendran et al.   SCIENCE