Leber’s hereditary optic neuropathy: Current approaches and future perspectives on Mesenchymal stem cell-mediated rescue
出版年份 2021 全文链接
标题
Leber’s hereditary optic neuropathy: Current approaches and future perspectives on Mesenchymal stem cell-mediated rescue
作者
关键词
LHON, Mitochondrial dysfunction, Mesenchymal stem cell, Mitochondrial transfer, Tunneling nanotubes, Cell-mediated rescue
出版物
MITOCHONDRION
Volume 60, Issue -, Pages 201-218
出版商
Elsevier BV
发表日期
2021-08-26
DOI
10.1016/j.mito.2021.08.013
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Stable transplantation of human mitochondrial DNA by high-throughput, pressurized isolated mitochondrial delivery
- (2021) Alexander J Sercel et al. eLife
- Hereditary Optic Neuropathies: Induced Pluripotent Stem Cell-Based 2D/3D Approaches
- (2021) Marta García-López et al. Genes
- Challenges and advances in clinical applications of mesenchymal stromal cells
- (2021) Tian Zhou et al. Journal of Hematology & Oncology
- The association between multiple risk factors, clinical correlations and molecular insights in Parkinson’s disease patients from Tamil Nadu population, India
- (2021) Dhivya Venkatesan et al. NEUROSCIENCE LETTERS
- KOBAS-i: intelligent prioritization and exploratory visualization of biological functions for gene enrichment analysis
- (2021) Dechao Bu et al. NUCLEIC ACIDS RESEARCH
- Does retina play a role in Parkinson's Disease?
- (2020) Subramaniam Mohana Devi et al. ACTA NEUROLOGICA BELGICA
- Systemic Mesenchymal Stem Cell Treatment Mitigates Structural and Functional Retinal Ganglion Cell Degeneration in a Mouse Model of Multiple Sclerosis
- (2020) Oliver W. Gramlich et al. Translational Vision Science & Technology
- Generation of a human iPSC line, FINCBi001-A, carrying a homoplasmic m.G3460A mutation in MT-ND1 associated with Leber’s Hereditary optic Neuropathy (LHON)
- (2020) Camille Peron et al. Stem Cell Research
- Stable retention of chloramphenicol-resistant mtDNA to rescue metabolically impaired cells
- (2020) Emma R. Dawson et al. Scientific Reports
- Potential of mesenchymal stem cells as topical immunomodulatory cell therapies for ocular surface inflammatory disorders
- (2020) Lydia J. Beeken et al. Stem Cells Translational Medicine
- Whole Mitochondrial Genome Analysis in Serbian Cases of Leber’s Hereditary Optic Neuropathy
- (2020) Phepy G. A. Dawod et al. Genes
- Mesenchymal Stem Cells as a Promising Cell Source for Integration in Novel In Vitro Models
- (2020) Ann-Kristin Afflerbach et al. Biomolecules
- Bilateral visual improvement with unilateral gene therapy injection for Leber hereditary optic neuropathy
- (2020) Patrick Yu-Wai-Man et al. Science Translational Medicine
- Pressure-Driven Mitochondrial Transfer Pipeline Generates Mammalian Cells of Desired Genetic Combinations and Fates
- (2020) Alexander N. Patananan et al. Cell Reports
- Sex Hormones and Optic Nerve Disorders: A Review
- (2019) Raffaele Nuzzi et al. Frontiers in Neuroscience
- Immune Response and Intraocular Inflammation in Patients With Leber Hereditary Optic Neuropathy Treated With Intravitreal Injection of Recombinant Adeno-Associated Virus 2 Carrying the ND4 Gene
- (2019) Céline Bouquet et al. JAMA Ophthalmology
- Challenges and Controversies in Human Mesenchymal Stem Cell Therapy
- (2019) Barbara Lukomska et al. Stem Cells International
- Concise Review: Challenges in Clinical Development of Mesenchymal Stromal/Stem Cells
- (2019) Ilenia Mastrolia et al. Stem Cells Translational Medicine
- Mitochondrial Calcium Uniporter as a potential therapeutic strategy for Alzheimer’s disease (AD)
- (2019) Venugopal Anila et al. ACTA NEUROPSYCHIATRICA
- Spatially selective activation of the visual cortex via intraneural stimulation of the optic nerve
- (2019) Vivien Gaillet et al. Nature Biomedical Engineering
- Leber’s Hereditary Optic Neuropathy as a Promising Disease for Gene Therapy Development
- (2019) Cuneyt Karaarslan ADVANCES IN THERAPY
- An update on retinal prostheses
- (2019) Lauren N. Ayton et al. CLINICAL NEUROPHYSIOLOGY
- Potential therapeutic application of mesenchymal stem cells in ophthalmology
- (2019) E. Yu Zakirova et al. EXPERIMENTAL EYE RESEARCH
- Choroidal thickness and the retinal ganglion cell complex in chronic Leberʼs hereditary optic neuropathy: a prospective study using swept-source optical coherence tomography
- (2019) Fatemeh Darvizeh et al. EYE
- Mesenchymal stromal cells in cancer: a review of their immunomodulatory functions and dual effects on tumor progression
- (2019) Sabine Galland et al. JOURNAL OF PATHOLOGY
- A novel mutation in the mitochondrial MT-ND5 gene in a family with MELAS. The relevance of genetic analysis on targeted tissues
- (2019) Luísa Panadés-de Oliveira et al. MITOCHONDRION
- Bioactivity and gene expression profiles of hiPSC-generated retinal ganglion cells in MT-ND4 mutated Leber's hereditary optic neuropathy
- (2018) You-Ren Wu et al. EXPERIMENTAL CELL RESEARCH
- Mitochondrial Damage-Associated Molecular Patterns: From Inflammatory Signaling to Human Diseases
- (2018) Serge Grazioli et al. Frontiers in Immunology
- Current and Emerging Treatment Modalities for Leber’s Hereditary Optic Neuropathy: A Review of the Literature
- (2018) Anna Theodorou-Kanakari et al. ADVANCES IN THERAPY
- Whole exome sequencing revealed a novel mutation of MT-ND5 gene in a mitochondrial cardiomyopathy pedigree: patients showed biventricular hypertrophy, hyperlactacidemia, pulmonary hypertension, decreased exercise tolerance
- (2018) Nianwei Zhou Anatolian Journal of Cardiology
- Pharmaceutical Development of AAV-Based Gene Therapy Products for the Eye
- (2018) Gerard A. Rodrigues et al. PHARMACEUTICAL RESEARCH
- Novel MT-ND5 gene mutation identified in Leber's hereditary optic neuropathy patient using mitochondrial genome sequencing
- (2017) Moon-Woo Seong et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- The promise of stem cell-based therapeutics in ophthalmology
- (2017) Nitza Goldenberg-Cohen et al. Neural Regeneration Research
- Gene Therapy for Leber Hereditary Optic Neuropathy
- (2017) John Guy et al. OPHTHALMOLOGY
- Enhancement of Mitochondrial Transfer by Antioxidants in Human Mesenchymal Stem Cells
- (2017) Chia-Jung Li et al. Oxidative Medicine and Cellular Longevity
- Mitochondrial Transfer from Wharton’s Jelly Mesenchymal Stem Cell to MERRF Cybrid Reduces Oxidative Stress and Improves Mitochondrial Bioenergetics
- (2017) Yao-Chung Chuang et al. Oxidative Medicine and Cellular Longevity
- Modulation of oxidative phosphorylation and redox homeostasis in mitochondrial NDUFS4 deficiency via mesenchymal stem cells
- (2017) Marlen Melcher et al. Stem Cell Research & Therapy
- Artificial Mitochondria Transfer: Current Challenges, Advances, and Future Applications
- (2017) Andrés Caicedo et al. Stem Cells International
- Human bone marrow mesenchymal stem cells for retinal vascular injury
- (2016) Jin-Da Wang et al. ACTA OPHTHALMOLOGICA
- Study of mitochondrial respiratory defects on reprogramming to human induced pluripotent stem cells
- (2016) Sandy Hung et al. Aging-US
- Mitochondrial Transfer by Photothermal Nanoblade Restores Metabolite Profile in Mammalian Cells
- (2016) Ting-Hsiang Wu et al. Cell Metabolism
- Scanning Electron Microscopic Analysis of Biofilm Formation in Explanted Human Boston Type I Keratoprostheses
- (2016) Kavitha R. Sivaraman et al. CORNEA
- Intercellular mitochondrial transfer: bioenergetic crosstalk between cells
- (2016) Pratik Sinha et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Infections after keratoprosthesis
- (2016) Emma Davies et al. CURRENT OPINION IN OPHTHALMOLOGY
- Biochemical evidence for a mitochondrial genetic modifier in the phenotypic manifestation of Leber’s hereditary optic neuropathy-associated mitochondrial DNA mutation
- (2016) Pingping Jiang et al. HUMAN MOLECULAR GENETICS
- Gene Therapy for Leber Hereditary Optic Neuropathy
- (2016) William J. Feuer et al. OPHTHALMOLOGY
- Mitochondrial transfer of mesenchymal stem cells effectively protects corneal epithelial cells from mitochondrial damage
- (2016) Dan Jiang et al. Cell Death & Disease
- Mesenchymal stem cells and immunomodulation: current status and future prospects
- (2016) F Gao et al. Cell Death & Disease
- Characteristics of Mitochondrial Transformation into Human Cells
- (2016) E. E. Kesner et al. Scientific Reports
- Magnetomitotransfer: An efficient way for direct mitochondria transfer into cultured human cells
- (2016) Tanja Macheiner et al. Scientific Reports
- Stem Cell Therapy for Treatment of Ocular Disorders
- (2016) Padma Priya Sivan et al. Stem Cells International
- Bone Marrow-Derived Cells as a Therapeutic Approach to Optic Nerve Diseases
- (2016) Louise A. Mesentier-Louro et al. Stem Cells International
- iPSC-MSCs with High Intrinsic MIRO1 and Sensitivity to TNF-α Yield Efficacious Mitochondrial Transfer to Rescue Anthracycline-Induced Cardiomyopathy
- (2016) Yuelin Zhang et al. Stem Cell Reports
- Mesenchymal stem cell therapy in retinal and optic nerve diseases: An update of clinical trials
- (2016) Sonia Labrador-Velandia et al. World Journal of Stem Cells
- Human mesenchymal stem cells - current trends and future prospective
- (2015) Imran Ullah et al. BIOSCIENCE REPORTS
- Restoration of vision in blind individuals using bionic devices: A review with a focus on cortical visual prostheses
- (2015) Philip M. Lewis et al. BRAIN RESEARCH
- Transfer of mitochondria via tunneling nanotubes rescues apoptotic PC12 cells
- (2015) X Wang et al. CELL DEATH AND DIFFERENTIATION
- Is there treatment for Leber hereditary optic neuropathy?
- (2015) Jason H. Peragallo et al. CURRENT OPINION IN OPHTHALMOLOGY
- Mitochondrial complex I deficiency leads to inflammation and retinal ganglion cell death in the Ndufs4 mouse
- (2015) Alfred K. Yu et al. HUMAN MOLECULAR GENETICS
- NetworkAnalyst for statistical, visual and network-based meta-analysis of gene expression data
- (2015) Jianguo Xia et al. Nature Protocols
- Molecular Mechanisms Mediating Retinal Reactive Gliosis Following Bone Marrow Mesenchymal Stem Cell Transplantation
- (2015) Alessia Tassoni et al. STEM CELLS
- Cigarette toxicity triggers Leber’s hereditary optic neuropathy by affecting mtDNA copy number, oxidative phosphorylation and ROS detoxification pathways
- (2015) L Giordano et al. Cell Death & Disease
- Mesenchymal stem cells use extracellular vesicles to outsource mitophagy and shuttle microRNAs
- (2015) Donald G. Phinney et al. Nature Communications
- MitoCeption as a new tool to assess the effects of mesenchymal stem/stromal cell mitochondria on cancer cell metabolism and function
- (2015) Andrés Caicedo et al. Scientific Reports
- Improving the Post-Stroke Therapeutic Potency of Mesenchymal Multipotent Stromal Cells by Cocultivation With Cortical Neurons: The Role of Crosstalk Between Cells
- (2015) Valentina A. Babenko et al. Stem Cells Translational Medicine
- Mitochondrial damage-associated molecular patterns and vascular function
- (2014) C. F. Wenceslau et al. EUROPEAN HEART JOURNAL
- Three-parent in vitro fertilization: gene replacement for the prevention of inherited mitochondrial diseases
- (2014) Paula Amato et al. FERTILITY AND STERILITY
- Mitochondrial disease associated with complex I (NADH-CoQ oxidoreductase) deficiency
- (2014) Immo E. Scheffler JOURNAL OF INHERITED METABOLIC DISEASE
- Miro 1 Knockdown in Stem Cells Inhibits Mitochondrial Donation Mediated Rescue of Bronchial Epithelial Injury
- (2013) Tanveer Ahmad et al. BIOPHYSICAL JOURNAL
- Efficient mitochondrial biogenesis drives incomplete penetrance in Leber’s hereditary optic neuropathy
- (2013) Carla Giordano et al. BRAIN
- Immunological characteristics of human mesenchymal stem cells and multipotent adult progenitor cells
- (2013) Sandra A Jacobs et al. IMMUNOLOGY AND CELL BIOLOGY
- Immunology of AAV-Mediated Gene Transfer in the Eye
- (2013) Keirnan Willett et al. Frontiers in Immunology
- Functional Recovery of Human Cells Harbouring the Mitochondrial DNA Mutation MERRF A8344G via Peptide-Mediated Mitochondrial Delivery
- (2012) Jui-Chih Chang et al. NEUROSIGNALS
- Rare Primary Mitochondrial DNA Mutations and Probable Synergistic Variants in Leber’s Hereditary Optic Neuropathy
- (2012) Alessandro Achilli et al. PLoS One
- Leber hereditary optic neuropathy and oxidative stress
- (2012) Y. Zhuo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Gene delivery to mitochondria by targeting modified adenoassociated virus suppresses Leber's hereditary optic neuropathy in a mouse model
- (2012) H. Yu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Biocompatibility and biofilm inhibition of N,N-hexyl,methyl-polyethylenimine bonded to Boston Keratoprosthesis materials
- (2011) Irmgard Behlau et al. BIOMATERIALS
- Atypical presentation of Leigh syndrome associated with a Leber hereditary optic neuropathy primary mitochondrial DNA mutation
- (2011) Gary Fruhman et al. MOLECULAR GENETICS AND METABOLISM
- Induction of Rapid and Highly Efficient Expression of the Human ND4 Complex I Subunit in the Mouse Visual System by Self-complementary Adeno-Associated Virus
- (2010) Rajeshwari D. Koilkonda ARCHIVES OF OPHTHALMOLOGY
- DNA methylation status of nuclear-encoded mitochondrial genes underlies the tissue-dependent mitochondrial functions
- (2010) Masaki Takasugi et al. BMC GENOMICS
- A Mesoderm-Derived Precursor for Mesenchymal Stem and Endothelial Cells
- (2010) Maxim A. Vodyanik et al. Cell Stem Cell
- Mesenchymal Stem Cells and Potential Applications in Treating Ocular Disease
- (2010) Aaron W Joe et al. CURRENT EYE RESEARCH
- NDUFS4 mutations cause Leigh syndrome with predominant brainstem involvement
- (2009) E. Leshinsky-Silver et al. MOLECULAR GENETICS AND METABOLISM
- Replicative Senescence of Mesenchymal Stem Cells: A Continuous and Organized Process
- (2008) Wolfgang Wagner et al. PLoS One
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started