标题
Metabolic reprograming confers tamoxifen resistance in breast cancer
作者
关键词
Breast cancer, Estrogen receptor, Tamoxifen, Tamoxifen resistance, Metabolism
出版物
CHEMICO-BIOLOGICAL INTERACTIONS
Volume 347, Issue -, Pages 109602
出版商
Elsevier BV
发表日期
2021-07-28
DOI
10.1016/j.cbi.2021.109602
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- S-adenosylhomocysteine (AdoHcy)-dependent methyltransferase inhibitor DZNep overcomes breast cancer tamoxifen resistance via induction of NSD2 degradation and suppression of NSD2-driven redox homeostasis
- (2020) Qianqian Wang et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Aberrant fatty acid profile and FFAR4 signaling confer endocrine resistance in breast cancer
- (2019) Xiao Chu et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- LLGL2 rescues nutrient stress by promoting leucine uptake in ER+ breast cancer
- (2019) Yasuhiro Saito et al. NATURE
- Reprogramming of Amino Acid Transporters to Support Aspartate and Glutamate Dependency Sustains Endocrine Resistance in Breast Cancer
- (2019) Marina Bacci et al. Cell Reports
- Breast cancer statistics, 2019
- (2019) Carol E. DeSantis et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Mitochondrial fragmentation, elevated mitochondrial superoxide and respiratory supercomplexes disassembly is connected with the tamoxifen-resistant phenotype of breast cancer cells
- (2019) Veronika Tomková et al. FREE RADICAL BIOLOGY AND MEDICINE
- Lactate in the Regulation of Tumor Microenvironment and Therapeutic Approaches
- (2019) Karen G. de la Cruz-López et al. Frontiers in Oncology
- Expression of HIF-1α is related to a poor prognosis and tamoxifen resistance in contralateral breast cancer
- (2019) Annika Jögi et al. PLoS One
- Branched-chain amino acid metabolism in cancer
- (2018) Elitsa A. Ananieva et al. CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE
- The Human SLC7A5 (LAT1): The Intriguing Histidine/Large Neutral Amino Acid Transporter and Its Relevance to Human Health
- (2018) Mariafrancesca Scalise et al. Frontiers in Chemistry
- Association of tamoxifen resistance and lipid reprogramming in breast cancer
- (2018) Susanne Hultsch et al. BMC CANCER
- Pyruvate kinase M2 interacts with mammalian sterile 20-like kinase 1 and inhibits tamoxifen-induced apoptosis in human breast cancer cells
- (2017) Feihu Ji et al. TUMOR BIOLOGY
- Phosphoserine aminotransferase 1 is associated to poor outcome on tamoxifen therapy in recurrent breast cancer
- (2017) Tommaso De Marchi et al. Scientific Reports
- Volatile metabolomic signature of human breast cancer cell lines
- (2017) Catarina L. Silva et al. Scientific Reports
- Curcumin suppresses 4-hydroxytamoxifen resistance in breast cancer cells by targeting SLUG/Hexokinase 2 pathway
- (2016) Chong Geng et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Reprogramming metabolism by histone methyltransferase NSD2 drives endocrine resistance via coordinated activation of pentose phosphate pathway enzymes
- (2016) Junjian Wang et al. CANCER LETTERS
- AMPK Activation and Metabolic Reprogramming by Tamoxifen through Estrogen Receptor-Independent Mechanisms Suggests New Uses for This Therapeutic Modality in Cancer Treatment
- (2016) N. A. Daurio et al. CANCER RESEARCH
- The importance of serine metabolism in cancer
- (2016) Katherine R. Mattaini et al. JOURNAL OF CELL BIOLOGY
- Metabolic regulation of mitochondrial dynamics
- (2016) Prashant Mishra et al. JOURNAL OF CELL BIOLOGY
- Supporting Aspartate Biosynthesis Is an Essential Function of Respiration in Proliferating Cells
- (2015) Lucas B. Sullivan et al. CELL
- Altered regulation of PDK4 expression promotes antiestrogen resistance in human breast cancer cells
- (2015) William Walter et al. SpringerPlus
- Inhibition of Aerobic Glycolysis Represses Akt/mTOR/HIF-1α Axis and Restores Tamoxifen Sensitivity in Antiestrogen-Resistant Breast Cancer Cells
- (2015) Yu Mi Woo et al. PLoS One
- How Many Etiological Subtypes of Breast Cancer: Two, Three, Four, Or More?
- (2014) W. F. Anderson et al. JNCI-Journal of the National Cancer Institute
- MYC regulates the unfolded protein response and glucose and glutamine uptake in endocrine resistant breast cancer
- (2014) Ayesha N Shajahan-Haq et al. Molecular Cancer
- A kinase inhibitor screen identifies Mcl-1 and Aurora kinase A as novel treatment targets in antiestrogen-resistant breast cancer cells
- (2014) S Thrane et al. ONCOGENE
- Mechanisms associated with resistance to tamoxifen in estrogen receptor-positive breast cancer (Review)
- (2014) RUBÍ VIEDMA-RODRÍGUEZ et al. ONCOLOGY REPORTS
- Mitochondrial and cellular mechanisms for managing lipid excess
- (2014) Miguel A. Aon et al. Frontiers in Physiology
- Pathway-Centric Integrative Analysis Identifies RRM2 as a Prognostic Marker in Breast Cancer Associated with Poor Survival and Tamoxifen Resistance
- (2014) Nagireddy Putluri et al. NEOPLASIA
- The Wnt signalling pathway is upregulated in an in vitro model of acquired tamoxifen resistant breast cancer
- (2013) Yan Ni Loh et al. BMC CANCER
- Hexokinase 2 Is Required for Tumor Initiation and Maintenance and Its Systemic Deletion Is Therapeutic in Mouse Models of Cancer
- (2013) Krushna C. Patra et al. CANCER CELL
- Adipocyte-Derived Fibroblasts Promote Tumor Progression and Contribute to the Desmoplastic Reaction in Breast Cancer
- (2013) L. Bochet et al. CANCER RESEARCH
- MYC-driven accumulation of 2-hydroxyglutarate is associated with breast cancer prognosis
- (2013) Atsushi Terunuma et al. JOURNAL OF CLINICAL INVESTIGATION
- AKT-Induced Tamoxifen Resistance Is Overturned by RRM2 Inhibition
- (2013) Khyati N. Shah et al. MOLECULAR CANCER RESEARCH
- Lipogenesis and lipolysis: The pathways exploited by the cancer cells to acquire fatty acids
- (2013) Nousheen Zaidi et al. PROGRESS IN LIPID RESEARCH
- Elevation of cysteine consumption in tamoxifen-resistant MCF-7 cells
- (2012) Chang Seon Ryu et al. BIOCHEMICAL PHARMACOLOGY
- RNA-dependent inhibition of ribonucleotide reductase is a major pathway for 5-azacytidine activity in acute myeloid leukemia
- (2012) J. Aimiuwu et al. BLOOD
- Glutamine fuels a vicious cycle of autophagy in the tumor stroma and oxidative mitochondrial metabolism in epithelial cancer cells
- (2012) Ying-Hui Ko et al. CANCER BIOLOGY & THERAPY
- Cholesterol metabolism and resistance to tamoxifen
- (2012) Marc Poirot et al. CURRENT OPINION IN PHARMACOLOGY
- The pentose phosphate pathway: An antioxidant defense and a crossroad in tumor cell fate
- (2012) Chiara Riganti et al. FREE RADICAL BIOLOGY AND MEDICINE
- Ceramide-Antiestrogen Nanoliposomal Combinations--Novel Impact of Hormonal Therapy in Hormone-Insensitive Breast Cancer
- (2012) S. A. F. Morad et al. MOLECULAR CANCER THERAPEUTICS
- Strategies for subtypes—dealing with the diversity of breast cancer: highlights of the St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2011
- (2011) A. Goldhirsch et al. ANNALS OF ONCOLOGY
- Aerobic Glycolysis: Meeting the Metabolic Requirements of Cell Proliferation
- (2011) Sophia Y. Lunt et al. Annual Review of Cell and Developmental Biology
- Anti-estrogen resistance in breast cancer is induced by the tumor microenvironment and can be overcome by inhibiting mitochondrial function in epithelial cancer cells
- (2011) Ubaldo E. Martinez-Outschoorn et al. CANCER BIOLOGY & THERAPY
- Cancer-Associated Adipocytes Exhibit an Activated Phenotype and Contribute to Breast Cancer Invasion
- (2011) B. Dirat et al. CANCER RESEARCH
- Evidence for a stromal-epithelial “lactate shuttle” in human tumors
- (2011) Diana Whitaker-Menezes et al. CELL CYCLE
- A Gene Expression Signature from Human Breast Cancer Cells with Acquired Hormone Independence Identifies MYC as a Mediator of Antiestrogen Resistance
- (2011) T. W. Miller et al. CLINICAL CANCER RESEARCH
- SLC6A14 (ATB0,+) Protein, a Highly Concentrative and Broad Specific Amino Acid Transporter, Is a Novel and Effective Drug Target for Treatment of Estrogen Receptor-positive Breast Cancer
- (2011) Senthil Karunakaran et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Metabolic alterations in cancer cells and therapeutic implications
- (2011) Naima Hammoudi et al. Chinese Journal of Cancer
- The autophagic tumor stroma model of cancer
- (2010) Stephanos Pavlides et al. CELL CYCLE
- Oxidative stress in cancer associated fibroblasts drives tumor-stroma co-evolution
- (2010) Ubaldo E. Martinez-Outschoorn et al. CELL CYCLE
- Autophagy in cancer associated fibroblasts promotes tumor cell survival
- (2010) Ubaldo E. Martinez-Outschoorn et al. CELL CYCLE
- Glucose metabolism in cancer cells
- (2010) Alessandro Annibaldi et al. CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE
- Identification and pharmacological characterization of cholesterol-5,6-epoxide hydrolase as a target for tamoxifen and AEBS ligands
- (2010) P. de Medina et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- An Absence of Stromal Caveolin-1 Expression Predicts Early Tumor Recurrence and Poor Clinical Outcome in Human Breast Cancers
- (2009) Agnieszka K. Witkiewicz et al. AMERICAN JOURNAL OF PATHOLOGY
- Growth of hormone-dependent MCF-7 breast cancer cells is promoted by constitutive caveolin-1 whose expression is lost in an EGF-R-mediated manner during development of tamoxifen resistance
- (2009) Nicholas B. P. Thomas et al. BREAST CANCER RESEARCH AND TREATMENT
- Increased expression of enolase α in human breast cancer confers tamoxifen resistance in human breast cancer cells
- (2009) Shih-Hsin Tu et al. BREAST CANCER RESEARCH AND TREATMENT
- mTOR/S6K1 and MAPK/RSK signaling pathways coordinately regulate estrogen receptor α serine 167 phosphorylation
- (2009) Rachel L. Yamnik et al. FEBS LETTERS
- Q's next: the diverse functions of glutamine in metabolism, cell biology and cancer
- (2009) R J DeBerardinis et al. ONCOGENE
- Glutamine Deprivation Induces Abortive S-Phase Rescued by Deoxyribonucleotides in K-Ras Transformed Fibroblasts
- (2009) Daniela Gaglio et al. PLoS One
- MUC1-induced alterations in a lipid metabolic gene network predict response of human breast cancers to tamoxifen treatment
- (2009) S. P. Pitroda et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Principles of bioactive lipid signalling: lessons from sphingolipids
- (2008) Yusuf A. Hannun et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started