SLC6A14 (ATB0,+) Protein, a Highly Concentrative and Broad Specific Amino Acid Transporter, Is a Novel and Effective Drug Target for Treatment of Estrogen Receptor-positive Breast Cancer

Bortezomib blocks the catabolic process of autophagy via a cathepsin-dependent mechanism, affects endoplasmic reticulum stress, and induces caspase-dependent cell death in antiestrogen–sensitive and resistant ER+ breast cancer cells

(2010) Sudharsan Periyasamy-Thandavan et al.   Autophagy

The molecular determinants of de novo nucleotide biosynthesis in cancer cells

(2009) Xuemei Tong et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Nutrient control of TORC1, a cell-cycle regulator

(2009) Xuemin Wang et al.   TRENDS IN CELL BIOLOGY

ATF4-dependent transcription mediates signaling of amino acid limitation

(2009) Michael S. Kilberg et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Interaction of tryptophan derivatives with SLC6A14 (ATB0,+) reveals the potential of the transporter as a drug target for cancer chemotherapy

(2008) Senthil Karunakaran et al.   BIOCHEMICAL JOURNAL

The Biology of Cancer: Metabolic Reprogramming Fuels Cell Growth and Proliferation

(2008) Ralph J. DeBerardinis et al.   Cell Metabolism

Arginine Deprivation as a Targeted Therapy for Cancer

(2008) L. Feun et al.   CURRENT PHARMACEUTICAL DESIGN

A role for macroautophagy in protection against 4-hydroxytamoxifen-induced cell death and the development of antiestrogen resistance

(2008) J. S. Samaddar et al.   MOLECULAR CANCER THERAPEUTICS

Estradiol-estrogen receptor: A key interplay of the expression of syndecan-2 and metalloproteinase-9 in breast cancer cells

(2008) Olga Ch. Kousidou et al.   Molecular Oncology

Nutrient transporters in cancer: Relevance to Warburg hypothesis and beyond

(2008) Vadivel Ganapathy et al.   PHARMACOLOGY & THERAPEUTICS