Thermostability, Tunability, and Tenacity of RNA as Rubbery Anionic Polymeric Materials in Nanotechnology and Nanomedicine—Specific Cancer Targeting with Undetectable Toxicity

IsRNA1: De Novo Prediction and Blind Screening of RNA 3D Structures

(2021) Dong Zhang et al.   Journal of Chemical Theory and Computation

AnnapuRNA: A scoring function for predicting RNA-small molecule binding poses

(2021) Filip Stefaniak et al.   PLoS Computational Biology

RNA nanotechnology to build a dodecahedral genome of single-stranded RNA virus

(2021) Hui Li et al.   RNA Biology

Increasing the Potential Interacting Area of Nanomedicine Enhances Its Homotypic Cancer Targeting Efficacy

(2020) Jingyi Zhu et al.   ACS Nano

Exosomes and Lung cancer: Roles in pathophysiology, diagnosis and therapeutic applications

(2020) Atefeh Amiri et al.   CURRENT MEDICINAL CHEMISTRY

A novel coronavirus outbreak of global health concern

(2020) Chen Wang et al.   LANCET

A new coronavirus associated with human respiratory disease in China

(2020) Fan Wu et al.   NATURE

The entry of nanoparticles into solid tumours

(2020) Shrey Sindhwani et al.   NATURE MATERIALS

Investigating RNA editing in deep transcriptome datasets with REDItools and REDIportal

(2020) Claudio Lo Giudice et al.   Nature Protocols

A Novel Coronavirus from Patients with Pneumonia in China, 2019

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Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus–Infected Pneumonia

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Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation

(2020) Daniel Wrapp et al.   SCIENCE

Ultra-thermostable RNA nanoparticles for solubilizing and high-yield loading of paclitaxel for breast cancer therapy

(2020) Sijin Guo et al.   Nature Communications

Characterization of the receptor-binding domain (RBD) of 2019 novel coronavirus: implication for development of RBD protein as a viral attachment inhibitor and vaccine

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The emerging role of RNA modifications in the regulation of mRNA stability

(2020) Sung Ho Boo et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Prostate‐specific membrane antigen expression in the vasculature of primary lung carcinomas associates with faster metastatic dissemination to the brain

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The COVID-19 pandemic in the USA: what might we expect?

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First known person-to-person transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the USA

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If a coronavirus vaccine arrives, can the world make enough?

(2020) Roxanne Khamsi   NATURE

Structural basis of receptor recognition by SARS-CoV-2

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A nanoparticle’s pathway into tumours

(2020) Irene de Lázaro et al.   NATURE MATERIALS

Active transcytosis and new opportunities for cancer nanomedicine

(2020) Subehndu Pandit et al.   NATURE MATERIALS

Roles and mechanisms of alternative splicing in cancer — implications for care

(2020) Sophie C. Bonnal et al.   Nature Reviews Clinical Oncology

The regulation and functions of DNA and RNA G-quadruplexes

(2020) Dhaval Varshney et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

RNA delivery by extracellular vesicles in mammalian cells and its applications

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Vaccine designers take first shots at COVID-19

(2020) Jon Cohen   SCIENCE

Rapid COVID-19 vaccine development

(2020) Barney S. Graham   SCIENCE

Intron retention is a hallmark and spliceosome represents a therapeutic vulnerability in aggressive prostate cancer

(2020) Dingxiao Zhang et al.   Nature Communications

Potential for developing a SARS-CoV receptor-binding domain (RBD) recombinant protein as a heterologous human vaccine against coronavirus infectious disease (COVID)-19

(2020) Wen-Hsiang Chen et al.   Human Vaccines & Immunotherapeutics

MicroRNAs as Emerging Regulators of Signaling in the Tumor Microenvironment

(2020) Shahzad Nawaz Syed et al.   Cancers

AR/ER Ratio Correlates with Expression of Proliferation Markers and with Distinct Subset of Breast Tumors

(2020) Nelson Rangel et al.   Cells

RNA nanotechnology in synthetic biology

(2020) Jongmin Kim et al.   CURRENT OPINION IN BIOTECHNOLOGY

Progress toward the development of the small molecule equivalent of small interfering RNA

(2020) Matthew D. Disney et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Synthesis of Nucleobase-Modified RNA Oligonucleotides by Post-Synthetic Approach

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SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness

(2020) Kizzmekia S. Corbett et al.   NATURE

A large-scale binding and functional map of human RNA-binding proteins

(2020) Eric L. Van Nostrand et al.   NATURE

Phase 1/2 study of COVID-19 RNA vaccine BNT162b1 in adults

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(2020) Debby van Riel et al.   NATURE MATERIALS

COVID-19 vaccine development and a potential nanomaterial path forward

(2020) Matthew D. Shin et al.   Nature Nanotechnology

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(2020) Thomas C. Roberts et al.   NATURE REVIEWS DRUG DISCOVERY

Evaluation of the mRNA-1273 Vaccine against SARS-CoV-2 in Nonhuman Primates

(2020) Kizzmekia S. Corbett et al.   NEW ENGLAND JOURNAL OF MEDICINE

An mRNA Vaccine against SARS-CoV-2 — Preliminary Report

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Structure-based design of prefusion-stabilized SARS-CoV-2 spikes

(2020) Ching-Lin Hsieh et al.   SCIENCE

Theranostic Pretargeting Drug Delivery and Imaging Platforms in Cancer Precision Medicine

(2020) Sudath Hapuarachchige et al.   Frontiers in Oncology

RNA Nanoparticles as Rubber for Compelling Vessel Extravasation to Enhance Tumor Targeting and for Fast Renal Excretion to Reduce Toxicity

(2020) Chiran Ghimire et al.   ACS Nano

68Ga–Prostate-Specific Membrane Antigen PET–Positive Paget Bone Disease With Metastatic Prostatic Carcinoma

(2020) Ceren Ozge Engur et al.   CLINICAL NUCLEAR MEDICINE

RLDOCK: A New Method for Predicting RNA–Ligand Interactions

(2020) Li-Zhen Sun et al.   Journal of Chemical Theory and Computation

mRNA vaccine–induced neoantigen-specific T cell immunity in patients with gastrointestinal cancer

(2020) Gal Cafri et al.   JOURNAL OF CLINICAL INVESTIGATION

Large-scale tethered function assays identify factors that regulate mRNA stability and translation

(2020) En-Ching Luo et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Multivalent rubber-like RNA nanoparticles for targeted co-delivery of paclitaxel and MiRNA to silence the drug efflux transporter and liver cancer drug resistance

(2020) Hongzhi Wang et al.   JOURNAL OF CONTROLLED RELEASE

Self-assembling RNA Nanoparticle for Gene Expression Regulation in a Model System

(2019) Dominika Jedrzejczyk et al.   ACS Synthetic Biology

RNA-binding proteins distinguish between similar sequence motifs to promote targeted deadenylation by Ccr4-Not

(2019) Michael W Webster et al.   eLife

Autonomously designed free-form 2D DNA origami

(2019) Hyungmin Jun et al.   Science Advances

Toll-Like Receptor-Mediated Recognition of Nucleic Acid Nanoparticles (NANPs) in Human Primary Blood Cells

(2019) Enping Hong et al.   MOLECULES

Delivering the Messenger: Advances in Technologies for Therapeutic mRNA Delivery

(2019) Piotr S. Kowalski et al.   MOLECULAR THERAPY

Perspectives on targeting RNA with small molecules to capture opportunities at the intersection of chemistry, biology, and medicine

(2019) Matthew D. Disney   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

One-Pot Production of RNA Nanoparticles via Automated Processing and Self Assembly

(2019) Daniel L Jasinski et al.   ACS Nano

Genetically Encoded, Functional Single‐Strand RNA Origami: Anticoagulant

(2019) Abhichart Krissanaprasit et al.   ADVANCED MATERIALS

Exosomal miRNA Cargo as Mediator of Immune Escape Mechanisms in Neuroblastoma

(2019) Thomas D. Schmittgen   CANCER RESEARCH

Duplex Stem Replacement with bPNA+ Triplex Hybrid Stems Enables Reporting on Tertiary Interactions of Internal RNA Domains

(2019) Shiqin Miao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Where, When, and How: Context-Dependent Functions of RNA Methylation Writers, Readers, and Erasers

(2019) Hailing Shi et al.   MOLECULAR CELL

A Quantitative and Predictive Model for RNA Binding by Human Pumilio Proteins

(2019) Inga Jarmoskaite et al.   MOLECULAR CELL

Delivery of Anti-miRNA for Triple-Negative Breast Cancer Therapy Using RNA Nanoparticles Targeting Stem Cell Marker CD133

(2019) Hongran Yin et al.   MOLECULAR THERAPY

Responsive self-assembly of tectoRNAs with loop–receptor interactions from the tetrahydrofolate (THF) riboswitch

(2019) Charles Mitchell et al.   NUCLEIC ACIDS RESEARCH

VfoldLA: A web server for loop assembly-based prediction of putative 3D RNA structures

(2019) Xiaojun Xu et al.   JOURNAL OF STRUCTURAL BIOLOGY

5-methylcytosine promotes pathogenesis of bladder cancer through stabilizing mRNAs

(2019) Xin Chen et al.   NATURE CELL BIOLOGY

Biocompatible Macrocyclization between Cysteine and 2-Cyanopyridine Generates Stable Peptide Inhibitors

(2019) Christoph Nitsche et al.   ORGANIC LETTERS

Biodegradable polymers in gene‐silencing technology

(2019) Hossein Hosseinkhani et al.   POLYMERS FOR ADVANCED TECHNOLOGIES

Membrane protein-regulated networks across human cancers

(2019) Chun-Yu Lin et al.   Nature Communications

Estimating Strengths of Individual Hydrogen Bonds in RNA Base Pairs: Toward a Consensus between Different Computational Approaches

(2019) Antarip Halder et al.   ACS Omega

Survey of Clinical Translation of Cancer Nanomedicines—Lessons Learned from Successes and Failures

(2019) Hongliang He et al.   ACCOUNTS OF CHEMICAL RESEARCH

Duplex‐forming Oligonucleotide of Triazole‐linked RNA

(2019) Tomoko Fujino et al.   Chemistry-An Asian Journal

CDK 12 drives breast tumor initiation and trastuzumab resistance via WNT and IRS 1‐ErbB‐ PI 3K signaling

(2019) Hee‐Joo Choi et al.   EMBO REPORTS

The biogenesis, biology and characterization of circular RNAs

(2019) Lasse S. Kristensen et al.   NATURE REVIEWS GENETICS

Tuning the size, shape and structure of RNA nanoparticles for favorable cancer targeting and immunostimulation

(2019) Sijin Guo et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

RNA Nanotechnology to Solubilize Hydrophobic Antitumor Drug for Targeted Delivery

(2019) Xijun Piao et al.   Advanced Science

Molecular Dynamics Study of the Hybridization between RNA and Modified Oligonucleotides

(2019) Zhifeng Jing et al.   Journal of Chemical Theory and Computation

Folate-displaying exosome mediated cytosolic delivery of siRNA avoiding endosome trapping

(2019) Zhen Zheng et al.   JOURNAL OF CONTROLLED RELEASE

Recent advances in the detection of base modifications using the Nanopore sequencer

(2019) Liu Xu et al.   JOURNAL OF HUMAN GENETICS

Engineered extracellular vesicles and their mimetics for clinical translation

(2019) Hyejin Kim et al.   METHODS

Recent Advances in Bioorthogonal Click Chemistry for Efficient Synthesis of Radiotracers and Radiopharmaceuticals

(2019) Mushtaq et al.   MOLECULES

Nucleotide resolution profiling of m7G tRNA modification by TRAC-Seq

(2019) Shuibin Lin et al.   Nature Protocols

Improved stability of a novel fluorine-18 labeled TCO analogue for pretargeted PET imaging

(2019) Eduardo Ruivo et al.   NUCLEAR MEDICINE AND BIOLOGY

Linkage between endosomal escape of LNP-mRNA and loading into EVs for transport to other cells

(2019) Marco Maugeri et al.   Nature Communications

BRC-mediated RNAi targeting of USE1 inhibits tumor growth in vitro and in vivo

(2019) Hyejin Kim et al.   BIOMATERIALS

Aptamers Chemistry: Chemical Modifications and Conjugation Strategies

(2019) Fadwa Odeh et al.   MOLECULES

The Biogenesis and Precise Control of RNA m6A Methylation

(2019) Huilin Huang et al.   TRENDS IN GENETICS

Single Functionalized pRNA/Gold Nanoparticle for Ultrasensitive MicroRNA Detection Using Electrochemical Surface‐Enhanced Raman Spectroscopy

(2019) Taek Lee et al.   Advanced Science

Large-scale generation of functional mRNA-encapsulating exosomes via cellular nanoporation

(2019) Zhaogang Yang et al.   Nature Biomedical Engineering

Multifluorophore DNA Origami Beacon as a Biosensing Platform

(2018) Denis Selnihhin et al.   ACS Nano

Solid-Phase Nucleic Acid Sequence-Based Amplification and Length-Scale Effects during RNA Amplification

(2018) Youlong Ma et al.   ANALYTICAL CHEMISTRY

RiboSketch: Versatile Visualization of Multi-stranded RNA and DNA Secondary Structure

(2018) Jacob S Lu et al.   BIOINFORMATICS

An RNA Origami Octahedron with Intrinsic siRNAs for Potent Gene Knockdown

(2018) Hans Christian Høiberg et al.   Biotechnology Journal

In Vitro and In Vivo evaluation of a novel folate-targeted theranostic nanoemulsion of docetaxel for imaging and improved anticancer activity against ovarian cancers

(2018) Niravkumar R. Patel et al.   CANCER BIOLOGY & THERAPY

Favorable biodistribution, specific targeting and conditional endosomal escape of RNA nanoparticles in cancer therapy

(2018) Congcong Xu et al.   CANCER LETTERS

Photomodulating Gene Expression by Using Caged siRNAs with Single-Aptamer Modification

(2018) Liangliang Zhang et al.   CHEMBIOCHEM

Click Chemistry in Sphingolipid Research

(2018) Eduardo Izquierdo et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Hydrophobic Effect from Conjugated Chemicals or Drugs on In Vivo Biodistribution of RNA Nanoparticles

(2018) Daniel L. Jasinski et al.   HUMAN GENE THERAPY

IsRNA: An Iterative Simulated Reference State Approach to Modeling Correlated Interactions in RNA Folding

(2018) Dong Zhang et al.   Journal of Chemical Theory and Computation

RNA-based micelles: A novel platform for paclitaxel loading and delivery

(2018) Yi Shu et al.   JOURNAL OF CONTROLLED RELEASE

Potential use of prostate specific membrane antigen (PSMA) for detecting the tumor neovasculature of brain tumors by PET imaging with 89Zr-Df-IAB2M anti-PSMA minibody

(2018) Masahide Matsuda et al.   JOURNAL OF NEURO-ONCOLOGY

Predicting Cotranscriptional Folding Kinetics For Riboswitch

(2018) Ting-ting Sun et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Methods for construction and characterization of simple or special multifunctional RNA nanoparticles based on the 3WJ of phi29 DNA packaging motor

(2018) Sijin Guo et al.   METHODS

mRNA Deadenylation Is Coupled to Translation Rates by the Differential Activities of Ccr4-Not Nucleases

(2018) Michael W. Webster et al.   MOLECULAR CELL

Structure and Composition Define Immunorecognition of Nucleic Acid Nanoparticles

(2018) Enping Hong et al.   NANO LETTERS

mRNA vaccines — a new era in vaccinology

(2018) Norbert Pardi et al.   NATURE REVIEWS DRUG DISCOVERY

Principles for targeting RNA with drug-like small molecules

(2018) Katherine Deigan Warner et al.   NATURE REVIEWS DRUG DISCOVERY

Tapping the RNA world for therapeutics

(2018) Judy Lieberman   NATURE STRUCTURAL & MOLECULAR BIOLOGY

2′-O-methylation in mRNA disrupts tRNA decoding during translation elongation

(2018) Junhong Choi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Tapping the RNA world for therapeutics

(2018) Judy Lieberman   NATURE STRUCTURAL & MOLECULAR BIOLOGY

2′-O-methylation in mRNA disrupts tRNA decoding during translation elongation

(2018) Junhong Choi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Exosome Theranostics: Biology and Translational Medicine

(2018) Chuanjiang He et al.   Theranostics

Efficient Shielding of Polyplexes Using Heterotelechelic Polysarcosines

(2018) Philipp Klein et al.   Polymers

An RNA Origami Octahedron with Intrinsic siRNAs for Potent Gene Knockdown

(2018) Hans Christian Høiberg et al.   Biotechnology Journal

Aptamer Therapeutics in Cancer: Current and Future

(2018) Yoshihiro Morita et al.   Cancers

Prospects for a MERS-CoV spike vaccine

(2018) Yusen Zhou et al.   Expert Review of Vaccines

Fragile X mental retardation protein modulates the stability of its m6A-marked messenger RNA targets

(2018) Feiran Zhang et al.   HUMAN MOLECULAR GENETICS

Photo-controlled release of paclitaxel and model drugs from RNA pyramids

(2018) Congcong Xu et al.   Nano Research

Alnylam launches era of RNAi drugs

(2018) Ken Garber   NATURE BIOTECHNOLOGY

Consequences of Mg2+ binding on the geometry and stability of RNA base pairs

(2018) Antarip Halder et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Uniqueness, Advantages, Challenges, Solutions, and Perspectives in Therapeutics Applying RNA Nanotechnology

(2018) Peixuan Guo et al.   Nucleic Acid Therapeutics

Arrowtail RNA for Ligand Display on Ginger Exosome-like Nanovesicles to Systemic Deliver siRNA for Cancer Suppression

(2018) Zhefeng Li et al.   Scientific Reports

Precise Small Molecule Degradation of a Noncoding RNA Identifies Cellular Binding Sites and Modulates an Oncogenic Phenotype

(2018) Yue Li et al.   ACS Chemical Biology

RNA Micelles for the Systemic Delivery of Anti-miRNA for Cancer Targeting and Inhibition without Ligand

(2018) Hongran Yin et al.   ACS Nano

Acetylation of Cytidine in mRNA Promotes Translation Efficiency

(2018) Daniel Arango et al.   CELL

Synthetic RNA-based logic computation in mammalian cells

(2018) Satoshi Matsuura et al.   Nature Communications

Fluorogenic RNA Aptamers: A Nano-platform for Fabrication of Simple and Combinatorial Logic Gates

(2018) Victoria Goldsworthy et al.   Nanomaterials

Specific delivery of delta-5-desaturase siRNA via RNA nanoparticles supplemented with dihomo-γ-linolenic acid for colon cancer suppression

(2018) Yi Xu et al.   Redox Biology

RNA-DNA hybrid (R-loop) immunoprecipitation mapping: an analytical workflow to evaluate inherent biases

(2017) László Halász et al.   GENOME RESEARCH

Programmable formation of catalytic RNA triangles and squares by assembling modular RNA enzymes

(2017) Hiroki Oi et al.   JOURNAL OF BIOCHEMISTRY

Probing the mechanical properties, conformational changes, and interactions of nucleic acids with magnetic tweezers

(2017) Franziska Kriegel et al.   JOURNAL OF STRUCTURAL BIOLOGY

FDA-Approved Oligonucleotide Therapies in 2017

(2017) Cy A. Stein et al.   MOLECULAR THERAPY

Composing RNA Nanostructures from a Syntax of RNA Structural Modules

(2017) Cody Geary et al.   NANO LETTERS

RNA nanoparticles harboring annexin A2 aptamer can target ovarian cancer for tumor-specific doxorubicin delivery

(2017) Fengmei Pi et al.   Nanomedicine-Nanotechnology Biology and Medicine

Versatile RNA tetra-U helix linking motif as a toolkit for nucleic acid nanotechnology

(2017) My N. Bui et al.   Nanomedicine-Nanotechnology Biology and Medicine

Therapeutic effects of a novel siRNA-based anti-VEGF (siVEGF) nanoball for the treatment of choroidal neovascularization

(2017) Na-Kyung Ryoo et al.   Nanoscale

The chemical evolution of oligonucleotide therapies of clinical utility

(2017) Anastasia Khvorova et al.   NATURE BIOTECHNOLOGY

Overcoming cellular barriers for RNA therapeutics

(2017) Steven F Dowdy   NATURE BIOTECHNOLOGY

Nanoparticle orientation to control RNA loading and ligand display on extracellular vesicles for cancer regression

(2017) Fengmei Pi et al.   Nature Nanotechnology

Characterizing exogenous mRNA delivery, trafficking, cytoplasmic release and RNA–protein correlations at the level of single cells

(2017) Jonathan L. Kirschman et al.   NUCLEIC ACIDS RESEARCH

MODOMICS: a database of RNA modification pathways. 2017 update

(2017) Pietro Boccaletto et al.   NUCLEIC ACIDS RESEARCH

Single-stranded nucleic acid elasticity arises from internal electrostatic tension

(2017) David R. Jacobson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effect of removing Kupffer cells on nanoparticle tumor delivery

(2017) Anthony J. Tavares et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sequence determinants of the folding properties of box C/D kink-turns in RNA

(2017) Saira Ashraf et al.   RNA

MCTBI: a web server for predicting metal ion effects in RNA structures

(2017) Li-Zhen Sun et al.   RNA

Assessment and comparison of thermal stability of phosphorothioate-DNA, DNA, RNA, 2′-F RNA, and LNA in the context of Phi29 pRNA 3WJ

(2017) Xijun Piao et al.   RNA

Programmable Nucleic Acid Based Polygons with Controlled Neuroimmunomodulatory Properties for Predictive QSAR Modeling

(2017) Morgan Brittany Johnson et al.   Small

Extracellular Vesicles: Unique Intercellular Delivery Vehicles

(2017) Sybren L.N. Maas et al.   TRENDS IN CELL BIOLOGY

Development of novel long noncoding RNA MALAT1 near-infrared optical probes for in vivo tumour imaging

(2017) Meng-Jie Dong et al.   Oncotarget

RNA versatility, flexibility, and thermostability for practice in RNA nanotechnology and biomedical applications

(2017) Farzin Haque et al.   Wiley Interdisciplinary Reviews-RNA

Folding behavior of a T-shaped, ribosome-binding translation enhancer implicated in a wide-spread conformational switch

(2017) My-Tra Le et al.   eLife

Size, Shape, and Sequence-Dependent Immunogenicity of RNA Nanoparticles

(2017) Sijin Guo et al.   Molecular Therapy-Nucleic Acids

Solid-Phase Synthesis of Difficult Purine-Rich PNAs through Selective Hmb Incorporation: Application to the Total Synthesis of Cell Penetrating Peptide-PNAs

(2017) Julien Tailhades et al.   Frontiers in Chemistry

Directional mechanical stability of Bacteriophage φ29 motor’s 3WJ-pRNA: Extraordinary robustness along portal axis

(2017) Zhonghe Xu et al.   Science Advances

Engineering CRISPR–Cpf1 crRNAs and mRNAs to maximize genome editing efficiency

(2017) Bin Li et al.   Nature Biomedical Engineering

Overcoming Tamoxifen Resistance of Human Breast Cancer by Targeted Gene Silencing Using Multifunctional pRNA Nanoparticles

(2016) Yijuan Zhang et al.   ACS Nano

Controllable Self-Assembly of RNA Tetrahedrons with Precise Shape and Size for Cancer Targeting

(2016) Hui Li et al.   ADVANCED MATERIALS

Fabrication of RNA 3D Nanoprisms for Loading and Protection of Small RNAs and Model Drugs

(2016) Emil F. Khisamutdinov et al.   ADVANCED MATERIALS

Limits of RNA 2′-OH Mimicry by Fluorine: Crystal Structure of Bacillus halodurans RNase H Bound to a 2′-FRNA:DNA Hybrid

(2016) Pradeep S. Pallan et al.   BIOCHEMISTRY

Synthesis and properties of peptide nucleic acid labeled at the N-terminus with HiLyte Fluor 488 fluorescent dye

(2016) Dziyana Hnedzko et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synergistic effect of phosphorothioate, 5′-vinylphosphonate and GalNAc modifications for enhancing activity of synthetic siRNA

(2016) Thazha P. Prakash et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

In vitrotoxicology studies of extracellular vesicles

(2016) Sayantan Maji et al.   JOURNAL OF APPLIED TOXICOLOGY

Monte Carlo Tightly Bound Ion Model: Predicting Ion-Binding Properties of RNA with Ion Correlations and Fluctuations

(2016) Li-Zhen Sun et al.   Journal of Chemical Theory and Computation

Tumoral gene silencing by receptor-targeted combinatorial siRNA polyplexes

(2016) Dian-Jang Lee et al.   JOURNAL OF CONTROLLED RELEASE

The Medicinal Chemistry of Therapeutic Oligonucleotides

(2016) W. Brad Wan et al.   JOURNAL OF MEDICINAL CHEMISTRY

Silver nanoparticles-quercetin conjugation to siRNA against drug-resistant Bacillus subtilis for effective gene silencing: in vitro and in vivo

(2016) Dongdong Sun et al.   Materials Science & Engineering C-Materials for Biological Applications

Structural computational modeling of RNA aptamers

(2016) Xiaojun Xu et al.   METHODS

Specific Delivery of MiRNA for High Efficient Inhibition of Prostate Cancer by RNA Nanotechnology

(2016) Daniel W Binzel et al.   MOLECULAR THERAPY

Lipid Nanoparticle Assisted mRNA Delivery for Potent Cancer Immunotherapy

(2016) Matthias A. Oberli et al.   NANO LETTERS

Challenges of clinical translation in nanomedicine: A qualitative study

(2016) Priya Satalkar et al.   Nanomedicine-Nanotechnology Biology and Medicine

Controllable self-assembly of RNA dendrimers

(2016) Ashwani Sharma et al.   Nanomedicine-Nanotechnology Biology and Medicine

Programmable RNA microstructures for coordinated delivery of siRNAs

(2016) Jaimie Marie Stewart et al.   Nanoscale

Reversible methylation of m6Am in the 5′ cap controls mRNA stability

(2016) Jan Mauer et al.   NATURE

Precise small-molecule recognition of a toxic CUG RNA repeat expansion

(2016) Suzanne G Rzuczek et al.   Nature Chemical Biology

Elasticity of the transition state for oligonucleotide hybridization

(2016) Kevin D. Whitley et al.   NUCLEIC ACIDS RESEARCH

SimRNAweb: a web server for RNA 3D structure modeling with optional restraints

(2016) Marcin Magnus et al.   NUCLEIC ACIDS RESEARCH

2′-O-Methyl- and 2′-O-propargyl-5-methylisocytidine: synthesis, properties and impact on the isoCd–dG and the isoCd–isoGd base pairing in nucleic acids with parallel and antiparallel strand orientation

(2016) Sunit K. Jana et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Staphylococcus aureus Sortase A-Mediated Incorporation of Peptides: Effect of Peptide Modification on Incorporation

(2016) Silvie Hansenová Maňásková et al.   PLoS One

Proximal disruptor aided ligation (ProDAL) of kilobase-long RNAs

(2016) Alexander Zhovmer et al.   RNA Biology

Mechanism of three-component collision to produce ultrastable pRNA three-way junction of Phi29 DNA-packaging motor by kinetic assessment

(2016) Daniel W. Binzel et al.   RNA

Mixed Nanosized Polymeric Micelles as Promoter of Doxorubicin and miRNA-34a Co-Delivery Triggered by Dual Stimuli in Tumor Tissue

(2016) Giuseppina Salzano et al.   Small

Generation of siRNA Nanosheets for Efficient RNA Interference

(2016) Hyejin Kim et al.   Scientific Reports

Systemic Delivery of Anti-miRNA for Suppression of Triple Negative Breast Cancer Utilizing RNA Nanotechnology

(2015) Dan Shu et al.   ACS Nano

Construction of RNA–Quantum Dot Chimera for Nanoscale Resistive Biomemory Application

(2015) Taek Lee et al.   ACS Nano

Delivery of RNA Nanoparticles into Colorectal Cancer Metastases Following Systemic Administration

(2015) Piotr Rychahou et al.   ACS Nano

Positron Emission Tomography Based Elucidation of the Enhanced Permeability and Retention Effect in Dogs with Cancer Using Copper-64 Liposomes

(2015) Anders E. Hansen et al.   ACS Nano

Parallel Comparative Studies on Mouse Toxicity of Oxide Nanoparticle- and Gadolinium-Based T1 MRI Contrast Agents

(2015) Rui Chen et al.   ACS Nano

Pharmacokinetics, biodistribution and cell uptake of antisense oligonucleotides

(2015) Richard S. Geary et al.   ADVANCED DRUG DELIVERY REVIEWS

A Multi-RNAi Microsponge Platform for Simultaneous Controlled Delivery of Multiple Small Interfering RNAs

(2015) Young Hoon Roh et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

In-vitro nanodiagnostic platform through nanoparticles and DNA-RNA nanotechnology

(2015) Ki Chan et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Role of Auf1 in elimination of oxidatively damaged messenger RNA in human cells

(2015) Takashi Ishii et al.   FREE RADICAL BIOLOGY AND MEDICINE

Synthesis and DNA/RNA Binding Properties of Conformationally Constrained Pyrrolidinyl PNA with a Tetrahydrofuran Backbone Deriving from Deoxyribose

(2015) Pitchanun Sriwarom et al.   JOURNAL OF ORGANIC CHEMISTRY

Mimicking Ribosomal Unfolding of RNA Pseudoknot in a Protein Channel

(2015) Xinyue Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Multifunctional Polymeric Micelles Co-loaded with Anti-Survivin siRNA and Paclitaxel Overcome Drug Resistance in an Animal Model of Ovarian Cancer

(2015) G. Salzano et al.   MOLECULAR CANCER THERAPEUTICS

RNA as a stable polymer to build controllable and defined nanostructures for material and biomedical applications

(2015) Hui Li et al.   Nano Today

Assembly of RNA nanostructures on supported lipid bilayers

(2015) Aleksandra P. Dabkowska et al.   Nanoscale

Visualizing lipid-formulated siRNA release from endosomes and target gene knockdown

(2015) Anders Wittrup et al.   NATURE BIOTECHNOLOGY

RNA mis-splicing in disease

(2015) Marina M. Scotti et al.   NATURE REVIEWS GENETICS

Synthesis of 2′-Fluoro RNA by Syn5 RNA polymerase

(2015) Bin Zhu et al.   NUCLEIC ACIDS RESEARCH

Transcription yield of fully 2′-modified RNA can be increased by the addition of thermostabilizing mutations to T7 RNA polymerase mutants

(2015) Adam J. Meyer et al.   NUCLEIC ACIDS RESEARCH

Nucleotide modifications within bacterial messenger RNAs regulate their translation and are able to rewire the genetic code

(2015) Thomas Philipp Hoernes et al.   NUCLEIC ACIDS RESEARCH

2′-Fluoro-modified phosphorothioate oligonucleotide can cause rapid degradation of P54nrb and PSF

(2015) Wen Shen et al.   NUCLEIC ACIDS RESEARCH

SimRNA: a coarse-grained method for RNA folding simulations and 3D structure prediction

(2015) Michal J. Boniecki et al.   NUCLEIC ACIDS RESEARCH

Postsynthetic Conjugation of RNA to Carboxylate and Dicarboxylate Molecules

(2015) Yossi Shemesh et al.   NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS

In Situ Imidazole Activation of Ribonucleotides for Abiotic RNA Oligomerization Reactions

(2015) Bradley T. Burcar et al.   ORIGINS OF LIFE AND EVOLUTION OF BIOSPHERES

RNA nanoparticle as a vector for targeted siRNA delivery into glioblastoma mouse model

(2015) Tae Jin Lee et al.   Oncotarget

Regression of Gastric Cancer by Systemic Injection of RNA Nanoparticles Carrying both Ligand and siRNA

(2015) Daxiang Cui et al.   Scientific Reports

Widespread intron retention diversifies most cancer transcriptomes

(2015) Heidi Dvinge et al.   Genome Medicine

TBI Server: A Web Server for Predicting Ion Effects in RNA Folding

(2015) Yuhong Zhu et al.   PLoS One

RNA Self-Assembly and RNA Nanotechnology

(2014) Wade W. Grabow et al.   ACCOUNTS OF CHEMICAL RESEARCH

Physicochemically Tunable Polyfunctionalized RNA Square Architecture with Fluorogenic and Ribozymatic Properties

(2014) Daniel L. Jasinski et al.   ACS Nano

RNA as a Boiling-Resistant Anionic Polymer Material To Build Robust Structures with Defined Shape and Stoichiometry

(2014) Emil F. Khisamutdinov et al.   ACS Nano

Selective Uptake and Imaging of Aptamer- and Antibody-Conjugated Hollow Nanospheres Targeted to Epidermal Growth Factor Receptors Overexpressed in Head and Neck Cancer

(2014) Marites Pasuelo Melancon et al.   ACS Nano

Triggering of RNA Interference with RNA–RNA, RNA–DNA, and DNA–RNA Nanoparticles

(2014) Kirill A. Afonin et al.   ACS Nano

Microbial Ecology Dynamics Reveal a Succession in the Core Microbiota Involved in the Ripening of Pasta Filata Caciocavallo Pugliese Cheese

(2014) Ilaria De Pasquale et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Entropy-Driven One-Step Formation of Phi29 pRNA 3WJ from Three RNA Fragments

(2014) Daniel W. Binzel et al.   BIOCHEMISTRY

High-Throughput Chemical Modification of Oligonucleotides for Systematic Structure–Activity Relationship Evaluation

(2014) Daniel Zewge et al.   BIOCONJUGATE CHEMISTRY

Global Analysis of mRNA Isoform Half-Lives Reveals Stabilizing and Destabilizing Elements in Yeast

(2014) Joseph V. Geisberg et al.   CELL

Widespread intron retention in mammals functionally tunes transcriptomes

(2014) Ulrich Braunschweig et al.   GENOME RESEARCH

The development of site-specific drug delivery nanocarriers based on receptor mediation

(2014) Xueqing Wang et al.   JOURNAL OF CONTROLLED RELEASE

De novo tertiary structure prediction using RNA123—benchmarking and application to Macugen

(2014) Emma S. E. Eriksson et al.   JOURNAL OF MOLECULAR MODELING

Oligonucleotides with “Clickable” Sugar Residues: Synthesis, Duplex Stability, and Terminal versus Central Interstrand Cross-Linking of 2′-O-Propargylated 2-Aminoadenosine with a Bifunctional Azide

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Independent Generation and Reactivity of Uridin-2′-yl Radical

(2014) Rakesh Paul et al.   JOURNAL OF ORGANIC CHEMISTRY

Multifunctional RNA Nanoparticles

(2014) Kirill A. Afonin et al.   NANO LETTERS

RNA intrusions change DNA elastic properties and structure

(2014) Hsiang-Chih Chiu et al.   Nanoscale

Pseudouridine profiling reveals regulated mRNA pseudouridylation in yeast and human cells

(2014) Thomas M. Carlile et al.   NATURE

Poly(A)-tail profiling reveals an embryonic switch in translational control

(2014) Alexander O. Subtelny et al.   NATURE

Enhancing immunomodulation on innate immunity by shape transition among RNA triangle, square and pentagon nanovehicles

(2014) Emil F. Khisamutdinov et al.   NUCLEIC ACIDS RESEARCH

Vfold: A Web Server for RNA Structure and Folding Thermodynamics Prediction

(2014) Xiaojun Xu et al.   PLoS One

Double-stranded RNA under force and torque: Similarities to and striking differences from double-stranded DNA

(2014) J. Lipfert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Predicting structure and stability for RNA complexes with intermolecular loop-loop base-pairing

(2014) S. Cao et al.   RNA

Dramatic Improvement of Crystals of Large RNAs by Cation Replacement and Dehydration

(2014) Jinwei Zhang et al.   STRUCTURE

Construction of RNA nanocages by re-engineering the packaging RNA of Phi29 bacteriophage

(2014) Chenhui Hao et al.   Nature Communications

mRNA vaccine CV9103 and CV9104 for the treatment of prostate cancer

(2014) Steffen Rausch et al.   Human Vaccines & Immunotherapeutics

Blind Predictions of DNA and RNA Tweezers Experiments with Force and Torque

(2014) Fang-Chieh Chou et al.   PLoS Computational Biology

Multifunctional polymeric micelles for delivery of drugs and siRNA

(2014) Aditi M. Jhaveri et al.   Frontiers in Pharmacology

Stable RNA nanoparticles as potential new generation drugs for cancer therapy

(2013) Yi Shu et al.   ADVANCED DRUG DELIVERY REVIEWS

Kinetics and Thermodynamics of DNA, RNA, and Hybrid Duplex Formation

(2013) Brittany Rauzan et al.   BIOCHEMISTRY

Highly Reactive trans-Cyclooctene Tags with Improved Stability for Diels–Alder Chemistry in Living Systems

(2013) Raffaella Rossin et al.   BIOCONJUGATE CHEMISTRY

Biochemical and haematological assessment of toxic effects of the leaf ethanol extract of Petroselinum crispum (Mill) Nyman ex A.W. Hill (Parsley) in rats

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Optimizing the selectivity of DIFO-based reagents for intracellular bioorthogonal applications

(2013) Eun J. Kim et al.   CARBOHYDRATE RESEARCH

Synthesis of Janus Compounds for the Recognition of G-U Mismatched Nucleobase Pairs

(2013) Gerard Artigas et al.   JOURNAL OF ORGANIC CHEMISTRY

General Approach for Introduction of Various Chemical Labels in Specific RNA Locations Based on Insertion of Amino Linkers

(2013) Dmitri Graifer et al.   MOLECULES

N6-methyladenosine-dependent regulation of messenger RNA stability

(2013) Xiao Wang et al.   NATURE

Natural RNA circles function as efficient microRNA sponges

(2013) Thomas B. Hansen et al.   NATURE

A window onto siRNA delivery

(2013) Yuhua Wang et al.   NATURE BIOTECHNOLOGY

Image-based analysis of lipid nanoparticle–mediated siRNA delivery, intracellular trafficking and endosomal escape

(2013) Jerome Gilleron et al.   NATURE BIOTECHNOLOGY

Activation of different split functionalities on re-association of RNA–DNA hybrids

(2013) Kirill A. Afonin et al.   Nature Nanotechnology

Fabrication of pRNA nanoparticles to deliver therapeutic RNAs and bioactive compounds into tumor cells

(2013) Yi Shu et al.   Nature Protocols

Alternative cleavage and polyadenylation: extent, regulation and function

(2013) Ran Elkon et al.   NATURE REVIEWS GENETICS

Programmable folding of fusion RNA in vivo and in vitro driven by pRNA 3WJ motif of phi29 DNA packaging motor

(2013) Dan Shu et al.   NUCLEIC ACIDS RESEARCH

RNA duplexes with abasic substitutions are potent and allele-selective inhibitors of huntingtin and ataxin-3 expression

(2013) J. Liu et al.   NUCLEIC ACIDS RESEARCH

Co-transcriptional production of RNA–DNA hybrids for simultaneous release of multiple split functionalities

(2013) Kirill A. Afonin et al.   NUCLEIC ACIDS RESEARCH

Design, synthesis and biological evaluation of novel antagonist compounds of Toll-like receptors 7, 8 and 9

(2013) Ekambar R. Kandimalla et al.   NUCLEIC ACIDS RESEARCH

Ocular Delivery of pRNA Nanoparticles: Distribution and Clearance After Subconjunctival Injection

(2013) Liang Feng et al.   PHARMACEUTICAL RESEARCH

Computational detection of abundant long-range nucleotide covariation in Drosophila genomes

(2013) E. Bindewald et al.   RNA

Automated classification of RNA 3D motifs and the RNA 3D Motif Atlas

(2013) A. I. Petrov et al.   RNA

Fabrication of 14 different RNA nanoparticles for specific tumor targeting without accumulation in normal organs

(2013) Y. Shu et al.   RNA

Crystal structure of 3WJ core revealing divalent ion-promoted thermostability and assembly of the Phi29 hexameric motor pRNA

(2013) H. Zhang et al.   RNA

Spherical Nucleic Acid Nanoparticle Conjugates as an RNAi-Based Therapy for Glioblastoma

(2013) S. A. Jensen et al.   Science Translational Medicine

RNAi-Microsponges Form through Self-Assembly of the Organic and Inorganic Products of Transcription

(2013) Kevin E. Shopsowitz et al.   Small

Exosome Encased Spherical Nucleic Acid Gold Nanoparticle Conjugates as Potent MicroRNA Regulation Agents

(2013) Ali H. Alhasan et al.   Small

Poxvirus DNA Replication

(2013) B. Moss   Cold Spring Harbor Perspectives in Biology

Multiplexed Nanoflares: mRNA Detection in Live Cells

(2012) Andrew E. Prigodich et al.   ANALYTICAL CHEMISTRY

Effects of Non-Nearest Neighbors on the Thermodynamic Stability of RNA GNRA Hairpin Tetraloops

(2012) Pamela L. Vanegas et al.   BIOCHEMISTRY

Interior Engineering of a Viral Nanoparticle and Its Tumor Homing Properties

(2012) Amy M. Wen et al.   BIOMACROMOLECULES

mRNA display selection and solid-phase synthesis of Fc-binding cyclic peptide affinity ligands

(2012) Stefano Menegatti et al.   BIOTECHNOLOGY AND BIOENGINEERING

Targeted polymeric therapeutic nanoparticles: design, development and clinical translation

(2012) Nazila Kamaly et al.   CHEMICAL SOCIETY REVIEWS

Automated prediction of three-way junction topological families in RNA secondary structures

(2012) Alexis Lamiable et al.   COMPUTATIONAL BIOLOGY AND CHEMISTRY

Extensive alternative polyadenylation during zebrafish development

(2012) I. Ulitsky et al.   GENOME RESEARCH

Polymeric micelles and alternative nanonized delivery vehicles for poorly soluble drugs

(2012) Ying Lu et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

RNA2D3D: A program for Generating, Viewing, and Comparing 3-Dimensional Models of RNA

(2012) Hugo M. Martinez et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

The effect of particle size on the biodistribution of low-modulus hydrogel PRINT particles

(2012) Timothy J. Merkel et al.   JOURNAL OF CONTROLLED RELEASE

Immobilized smart RNA on graphene oxide nanosheets to specifically recognize and adsorb trace peptide toxins in drinking water

(2012) Xiangang Hu et al.   JOURNAL OF HAZARDOUS MATERIALS

Solid-phase synthesis and screening of a library of C-terminal arginine peptide aldehydes against Murray Valley encephalitis virus protease

(2012) Nicholas J. Ede et al.   JOURNAL OF PEPTIDE SCIENCE

Protein Profiling of Active Cysteine Cathepsins in Living Cells Using an Activity-Based Probe Containing a Cell-Penetrating Peptide

(2012) Fengkai Fan et al.   JOURNAL OF PROTEOME RESEARCH

Mechanical Identities of RNA and DNA Double Helices Unveiled at the Single-Molecule Level

(2012) Elías Herrero-Galán et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Co-transcriptional Assembly of Chemically Modified RNA Nanoparticles Functionalized with siRNAs

(2012) Kirill A. Afonin et al.   NANO LETTERS

Ultrastable synergistic tetravalent RNA nanoparticles for targeting to cancers

(2012) Farzin Haque et al.   Nano Today

Self-assembled RNA interference microsponges for efficient siRNA delivery

(2012) Jong Bum Lee et al.   NATURE MATERIALS

Delivery of chemo-sensitizing siRNAs to HER2+-breast cancer cells using RNA aptamers

(2012) Kristina W. Thiel et al.   NUCLEIC ACIDS RESEARCH

Automated 3D structure composition for large RNAs

(2012) Mariusz Popenda et al.   NUCLEIC ACIDS RESEARCH

Widespread occurrence of 5-methylcytosine in human coding and non-coding RNA

(2012) Jeffrey E. Squires et al.   NUCLEIC ACIDS RESEARCH

Entropic origin of Mg2+-facilitated RNA folding

(2012) J. L. Fiore et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aptamers and the next generation of diagnostic reagents

(2012) Varatharasa Thiviyanathan et al.   Proteomics Clinical Applications

The role of the 3' untranslated region in post-transcriptional regulation of protein expression in mammalian cells.

(2012) Eva Matoulkova et al.   RNA Biology

Evolutionary Dynamics of Gene and Isoform Regulation in Mammalian Tissues

(2012) J. Merkin et al.   SCIENCE

The Evolutionary Landscape of Alternative Splicing in Vertebrate Species

(2012) N. L. Barbosa-Morais et al.   SCIENCE

Conjugation of PEG and gold nanoparticles to increase the accessibility and valency of tethered RNA splicing enhancers

(2012) Andrew J. Perrett et al.   Chemical Science

The tRNA methyltransferase NSun2 stabilizes p16INK4 mRNA by methylating the 3′-untranslated region of p16

(2012) Xiaotian Zhang et al.   Nature Communications

Global Patterns of Tissue-Specific Alternative Polyadenylation in Drosophila

(2012) Peter Smibert et al.   Cell Reports

Rolling Circle Transcription of Tandem siRNA to Generate Spherulitic RNA Nanoparticles for Cell Entry

(2012) Peixuan Guo   Molecular Therapy-Nucleic Acids

Development of Therapeutic-Grade Small Interfering RNAs by Chemical Engineering

(2012) Jesper B. Bramsen et al.   Frontiers in Genetics

Multistrand RNA Secondary Structure Prediction and Nanostructure Design Including Pseudoknots

(2011) Eckart Bindewald et al.   ACS Nano

Factors Controlling Nanoparticle Pharmacokinetics: An Integrated Analysis and Perspective

(2011) S.M. Moghimi et al.   Annual Review of Pharmacology and Toxicology

All-atom knowledge-based potential for RNA structure prediction and assessment

(2011) Emidio Capriotti et al.   BIOINFORMATICS

RAG: An update to the RNA-As-Graphs resource

(2011) Joseph A Izzo et al.   BMC BIOINFORMATICS

Hydrophobic Oxime Ethers: A Versatile Class of pDNA and siRNA Transfection Lipids

(2011) Souvik Biswas et al.   ChemMedChem

Nucleic Acid Aptamers: Clinical Applications and Promising New Horizons

(2011) X. Ni et al.   CURRENT MEDICINAL CHEMISTRY

Cotranscriptional folding kinetics of ribonucleic acid secondary structures

(2011) Peinan Zhao et al.   JOURNAL OF CHEMICAL PHYSICS

Physics-Based De Novo Prediction of RNA 3D Structures

(2011) Song Cao et al.   JOURNAL OF PHYSICAL CHEMISTRY B

RNA labeling, conjugation and ligation

(2011) Eduardo Paredes et al.   METHODS

Molecular Mechanisms of Long Noncoding RNAs

(2011) Kevin C. Wang et al.   MOLECULAR CELL

Pharmacological Characterization of Chemically Synthesized Monomeric phi29 pRNA Nanoparticles for Systemic Delivery

(2011) Sherine Abdelmawla et al.   MOLECULAR THERAPY

Self-Assembling RNA Nanorings Based on RNAI/II Inverse Kissing Complexes

(2011) Wade W. Grabow et al.   NANO LETTERS

A primer to scaffolded DNA origami

(2011) Carlos Ernesto Castro et al.   NATURE METHODS

Thermodynamically stable RNA three-way junction for constructing multifunctional nanoparticles for delivery of therapeutics

(2011) Dan Shu et al.   Nature Nanotechnology

Understanding the transcriptome through RNA structure

(2011) Yue Wan et al.   NATURE REVIEWS GENETICS

Self-assembling RNA square

(2011) S. M. Dibrov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transparent and Conducting Graphene-RNA-Based Nanocomposites

(2011) Faranak Sharifi et al.   Small

Target Flexibility in RNA−Ligand Docking Modeled by Elastic Potential Grids

(2011) Dennis M. Krüger et al.   ACS Medicinal Chemistry Letters

Rational Truncation of an RNA Aptamer to Prostate-Specific Membrane Antigen Using Computational Structural Modeling

(2011) William M. Rockey et al.   Nucleic Acid Therapeutics

Fabrication of Stable and RNase-Resistant RNA Nanoparticles Active in Gearing the Nanomotors for Viral DNA Packaging

(2010) Jing Liu et al.   ACS Nano

Dual-Channel Single-Molecule Fluorescence Resonance Energy Transfer to Establish Distance Parameters for RNA Nanoparticles

(2010) Dan Shu et al.   ACS Nano

The EPR effect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect

(2010) Jun Fang et al.   ADVANCED DRUG DELIVERY REVIEWS

Recent developments in oligonucleotide conjugation

(2010) Yashveer Singh et al.   CHEMICAL SOCIETY REVIEWS

MicroRNA: Biogenesis, Function and Role in Cancer

(2010) Leigh-Ann MacFarlane et al.   CURRENT GENOMICS

Breaking down the barriers: siRNA delivery and endosome escape

(2010) M. Dominska et al.   JOURNAL OF CELL SCIENCE

Noninvasive Visualization of RNA Delivery with 99mTc-Radiolabeled Small-Interference RNA in Tumor Xenografts

(2010) L. Kang et al.   JOURNAL OF NUCLEAR MEDICINE

Mechanistic Insights into Cu(I)-Catalyzed Azide−Alkyne “Click” Cycloaddition Monitored by Real Time Infrared Spectroscopy

(2010) Shengtong Sun et al.   JOURNAL OF PHYSICAL CHEMISTRY A

Effect of Nanoparticle Conjugation on Gene Silencing by RNA Interference

(2010) Neetu Singh et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Overexpression and Activation of the α9-Nicotinic Receptor During Tumorigenesis in Human Breast Epithelial Cells

(2010) Chia-Hwa Lee et al.   JNCI-Journal of the National Cancer Institute

Optimized method for the synthesis and purification of adenosine – Folic acid conjugates for use as transcription initiators in the preparation of modified RNA

(2010) Brian M. Laing et al.   METHODS

Drug Targeting Strategies in Cancer Treatment: An Overview

(2010) J. L. Arias   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Multiple mRNA Decapping Enzymes in Mammalian Cells

(2010) Man-Gen Song et al.   MOLECULAR CELL

Application of Phi29 Motor pRNA for Targeted Therapeutic Delivery of siRNA Silencing Metallothionein-IIA and Survivin in Ovarian Cancers

(2010) Pheruza Tarapore et al.   MOLECULAR THERAPY

An improved measurement of dsDNA elasticity using AFM

(2010) Thi-Huong Nguyen et al.   NANOTECHNOLOGY

A polyhedron made of tRNAs

(2010) Isil Severcan et al.   Nature Chemistry

Atomic accuracy in predicting and designing noncanonical RNA structure

(2010) Rhiju Das et al.   NATURE METHODS

In vitro assembly of cubic RNA-based scaffolds designed in silico

(2010) Kirill A. Afonin et al.   Nature Nanotechnology

The emerging field of RNA nanotechnology

(2010) Peixuan Guo   Nature Nanotechnology

The RNA modification database, RNAMDB: 2011 update

(2010) W. A. Cantara et al.   NUCLEIC ACIDS RESEARCH

Synthesis of Oligoribonucleic Acid Conjugates Using a Cyclooctyne Phosphoramidite

(2010) Pieter van Delft et al.   ORGANIC LETTERS

A structural database for k-turn motifs in RNA

(2010) K. T. Schroeder et al.   RNA

Predicting loop-helix tertiary structural contacts in RNA pseudoknots

(2010) S. Cao et al.   RNA

Heuristic RNA pseudoknot prediction including intramolecular kissing hairpins

(2010) J. Sperschneider et al.   RNA

Impact of Sugar Pucker on Base Pair and Mispair Stability

(2009) Adides A. Williams et al.   BIOCHEMISTRY

“Four-Potential” Ferrocene Labeling of PNA Oligomers via Click Chemistry

(2009) Nina Hüsken et al.   BIOCONJUGATE CHEMISTRY

Widespread Shortening of 3′UTRs by Alternative Cleavage and Polyadenylation Activates Oncogenes in Cancer Cells

(2009) Christine Mayr et al.   CELL

RNA-based computation in live cells

(2009) Yaakov Benenson   CURRENT OPINION IN BIOTECHNOLOGY

Reactivity-Dependent PCR: Direct, Solution-Phasein VitroSelection for Bond Formation

(2009) David J. Gorin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Inhibition of nitric oxide synthesis during induced cholestasis ameliorates hepatocellular injury by facilitating S-nitrosothiol homeostasis

(2009) Laura M López-Sánchez et al.   LABORATORY INVESTIGATION

Evaluation of specific delivery of chimeric phi29 pRNA/siRNA nanoparticles to multiple tumor cells

(2009) Li Li et al.   Molecular BioSystems

Square-Shaped RNA Particles from Different RNA Folds

(2009) Isil Severcan et al.   NANO LETTERS

Development trends for therapeutic antibody fragments

(2009) Aaron L Nelson et al.   NATURE BIOTECHNOLOGY

The non-coding RNA of the multidrug resistance-linked vault particle encodes multiple regulatory small RNAs

(2009) Helena Persson et al.   NATURE CELL BIOLOGY

A generic protocol for the expression and purification of recombinant RNA in Escherichia coli using a tRNA scaffold

(2009) Luc Ponchon et al.   Nature Protocols

35 years later, mRNA caps still matter

(2009) Anne-Claude Gingras   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Identification and classification of ncRNA molecules using graph properties

(2009) Liam Childs et al.   NUCLEIC ACIDS RESEARCH

DOCK 6: Combining techniques to model RNA-small molecule complexes

(2009) P. T. Lang et al.   RNA

Predicting structures and stabilities for H-type pseudoknots with interhelix loops

(2009) S. Cao et al.   RNA

Coarse-grained modeling of large RNA molecules with knowledge-based potentials and structural filters

(2009) M. A. Jonikas et al.   RNA

RNA Folding: Conformational Statistics, Folding Kinetics, and Ion Electrostatics

(2008) Shi-Jie Chen   Annual Review of Biophysics

siRNA Conjugate Delivery Systems

(2008) Ji Hoon Jeong et al.   BIOCONJUGATE CHEMISTRY

iFoldRNA: three-dimensional RNA structure prediction and folding

(2008) Shantanu Sharma et al.   BIOINFORMATICS

Nucleosides and oligonucleotides containing 1,2,3-triazole residues with nucleobase tethers: Synthesis via the azide-alkyne ‘click’ reaction

(2008) Padmaja Chittepu et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Design of (Gd-DO3A)n-polydiamidopropanoyl-peptide nucleic acid-D(Cys-Ser-Lys-Cys) magnetic resonance contrast agents

(2008) Nariman V. Amirkhanov et al.   BIOPOLYMERS

Rotational dynamics of HIV-1 nucleocapsid protein NCp7 as probed by a spin label attached by peptide synthesis

(2008) Zhiwen Zhang et al.   BIOPOLYMERS

Aminopeptidase N (APN/CD13) as a Target for Anti-Cancer Agent Design

(2008) Xiaopan Zhang et al.   CURRENT MEDICINAL CHEMISTRY

RNA folding and ribosome assembly

(2008) Sarah A Woodson   CURRENT OPINION IN CHEMICAL BIOLOGY

DDPH: Improving cognitive deficits beyond its α1-adrenoceptor antagonism in chronic cerebral hypoperfused rats

(2008) Zhi He et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Hinge Stiffness Is a Barrier to RNA Folding

(2008) Jörg C. Schlatterer et al.   JOURNAL OF MOLECULAR BIOLOGY

Computational strategies for the automated design of RNA nanoscale structures from building blocks using NanoTiler

(2008) Eckart Bindewald et al.   JOURNAL OF MOLECULAR GRAPHICS & MODELLING

5′-triphosphate-siRNA: turning gene silencing and Rig-I activation against melanoma

(2008) Hendrik Poeck et al.   NATURE MEDICINE

Short-hairpin RNAs synthesized by T7 phage polymerase do not induce interferon

(2008) T. Gondai et al.   NUCLEIC ACIDS RESEARCH

Subnanomolar antisense activity of phosphonate-peptide nucleic acid (PNA) conjugates delivered by cationic lipids to HeLa cells

(2008) Takehiko Shiraishi et al.   NUCLEIC ACIDS RESEARCH

Novel mechanism of hexamer ring assembly in protein/RNA interactions revealed by single molecule imaging

(2008) Feng Xiao et al.   NUCLEIC ACIDS RESEARCH

The UA_handle: a versatile submotif in stable RNA architectures†

(2008) Luc Jaeger et al.   NUCLEIC ACIDS RESEARCH

The oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA positioning

(2008) D. N. Wilson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Theory, analysis, and interpretation of single-molecule force spectroscopy experiments

(2008) O. K. Dudko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Annotation of tertiary interactions in RNA structures reveals variations and correlations

(2008) Y. Xin et al.   RNA

Analysis and classification of RNA tertiary structures

(2008) M. Abraham et al.   RNA

Factors affecting toxicity and efficacy of polymeric nanomedicines

(2008) Eiki Igarashi   TOXICOLOGY AND APPLIED PHARMACOLOGY

Specific RNA Self-Assembly with Minimal Paranemic Motifs

(2007) Kirill A. Afonin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY