标题
Aptamers Chemistry: Chemical Modifications and Conjugation Strategies
作者
关键词
-
出版物
MOLECULES
Volume 25, Issue 1, Pages 3
出版商
MDPI AG
发表日期
2019-12-23
DOI
10.3390/molecules25010003
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- An Electrochemical Aptamer-Based Sensor for Real-Time Monitoring of Insulin
- (2019) Yao Wu et al. ACS Sensors
- Aptamer-Conjugated Au Nanocage/SiO2 Core–Shell Bifunctional Nanoprobes with High Stability and Biocompatibility for Cellular SERS Imaging and Near-Infrared Photothermal Therapy
- (2019) Shengping Wen et al. ACS Sensors
- Optimization of a 40-mer Antimyelin DNA Aptamer Identifies a 20-mer with Enhanced Properties for Potential Multiple Sclerosis Therapy
- (2019) Brandon Wilbanks et al. Nucleic Acid Therapeutics
- Recent Advances in Aptamer Discovery and Applications
- (2019) Yang Zhang et al. MOLECULES
- Improved RE31 Analogues Containing Modified Nucleic Acid Monomers: Thermodynamic, Structural, and Biological Effects
- (2019) Weronika Kotkowiak et al. JOURNAL OF MEDICINAL CHEMISTRY
- Stability is not everything the case of the cyclization of the thrombin binding aptamer
- (2019) Claudia Riccardi et al. CHEMBIOCHEM
- High affinity of AS1411 toward copper; its application in a sensitive aptasensor for copper detection
- (2019) Amirhossein Bahreyni et al. ANALYTICAL BIOCHEMISTRY
- Aptamers as Therapeutic Agents: Has the Initial Euphoria Subsided?
- (2019) S. K. Haßel et al. Molecular Diagnosis & Therapy
- Investigating the properties of TBA variants with twin thrombin binding domains
- (2019) Teresa Amato et al. Scientific Reports
- Fine-tuning the properties of the thrombin binding aptamer through cyclization: Effect of the 5′-3′ connecting linker on the aptamer stability and anticoagulant activity
- (2019) Claudia Riccardi et al. BIOORGANIC CHEMISTRY
- A dimerization-based fluorogenic dye-aptamer module for RNA imaging in live cells
- (2019) Farah Bouhedda et al. Nature Chemical Biology
- Slow Off-Rate Modified Aptamer (SOMAmer) as a Novel Reagent in Immunoassay Development for Accurate Soluble Glypican-3 Quantification in Clinical Samples
- (2018) Jia Duo et al. ANALYTICAL CHEMISTRY
- Exploring the conformational behaviour and aggregation properties of lipid-conjugated AS1411 aptamers
- (2018) Claudia Riccardi et al. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
- In vivo inhibition of circulating tumor cells by two apoptosis-promoting circular aptamers with enhanced specificity
- (2018) Haiyan Dong et al. JOURNAL OF CONTROLLED RELEASE
- Aptamer-guided siRNA-loaded nanomedicines for systemic gene silencing in CD-44 expressing murine triple-negative breast cancer model
- (2018) Walhan Alshaer et al. JOURNAL OF CONTROLLED RELEASE
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- (2018) Lucía Martínez-Jothar et al. JOURNAL OF CONTROLLED RELEASE
- Implication of multivalent aptamers in DNA and DNA–RNA hybrid structures for efficient drug delivery in vitro and in vivo
- (2018) Yoon Young Kang et al. JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
- MUC1 aptamer-targeted DNA micelles for dual tumor therapy using doxorubicin and KLA peptide
- (2018) Fahimeh Charbgoo et al. Nanomedicine-Nanotechnology Biology and Medicine
- Identification and characterization of nucleobase-modified aptamers by click-SELEX
- (2018) Franziska Pfeiffer et al. Nature Protocols
- In Vivo SELEX of an Inhibitory NSCLC-Specific RNA Aptamer from PEGylated RNA Library
- (2018) Hanlu Wang et al. Molecular Therapy-Nucleic Acids
- Therapeutic aptamers in discovery, preclinical and clinical stages
- (2018) Said I. Ismail et al. ADVANCED DRUG DELIVERY REVIEWS
- Aptamer-guided nanomedicines for anticancer drug delivery
- (2018) Walhan Alshaer et al. ADVANCED DRUG DELIVERY REVIEWS
- Recent developments in cell-SELEX technology for aptamer selection
- (2018) Harleen Kaur BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- AS1411-decorated niosomes as effective nanocarriers for Ru(iii)-based drugs in anticancer strategies
- (2018) Claudia Riccardi et al. Journal of Materials Chemistry B
- Dimerization of an aptamer generated from Ligand-guided selection (LIGS) yields a high affinity scaffold against B-cells
- (2018) Sana Batool et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- A novel fluorometric method for inorganic pyrophosphatase detection based on G-quadruplex-thioflavin T
- (2018) Han Zhao et al. MOLECULAR AND CELLULAR PROBES
- Aptamer-functionalized hybrid nanoparticle for the treatment of breast cancer
- (2017) David Powell et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Aptamer-targeted delivery of Bcl-xL shRNA using alkyl modified PAMAM dendrimers into lung cancer cells
- (2017) Sara Ayatollahi et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Chemical Modifications of Nucleic Acid Aptamers for Therapeutic Purposes
- (2017) Shuaijian Ni et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Anti-FGFR1 aptamer-tagged superparamagnetic conjugates for anticancer hyperthermia therapy
- (2017) Przemysław M Jurek et al. International Journal of Nanomedicine
- Smart AS1411-aptamer conjugated pegylated PAMAM dendrimer for the superior delivery of camptothecin to colon adenocarcinoma in vitro and in vivo
- (2017) Mona Alibolandi et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
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- (2017) Fransisca Leonard et al. JOURNAL OF CONTROLLED RELEASE
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- (2017) Ilaria Monaco et al. JOURNAL OF MEDICINAL CHEMISTRY
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- (2017) Deepak Thirunavukarasu et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
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- (2017) Hailan Kuai et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Study and evaluation of nucleolin-targeted delivery of magnetic PLGA-PEG nanospheres loaded with doxorubicin to C6 glioma cells compared with low nucleolin-expressing L929 cells
- (2017) Jafar Mosafer et al. Materials Science & Engineering C-Materials for Biological Applications
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- (2017) Fengmei Pi et al. Nanomedicine-Nanotechnology Biology and Medicine
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- (2017) Marleen Renders et al. ORGANIC & BIOMOLECULAR CHEMISTRY
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- (2017) Yajun Wang et al. ORGANIC & BIOMOLECULAR CHEMISTRY
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- (2017) Bharat N. Gawande et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Smart Responsive Dual Aptamers-Targeted Bubble-Generating Nanosystem for Cancer Triplex Therapy and Ultrasound Imaging
- (2017) Feifei Zhao et al. Small
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- (2017) Zuochong Yu et al. Experimental and Therapeutic Medicine
- Effect of Chemical Modifications on Aptamer Stability in Serum
- (2017) Christina Kratschmer et al. Nucleic Acid Therapeutics
- Pharmacokinetic Properties of DNA Aptamers with Base Modifications
- (2017) Shashi Gupta et al. Nucleic Acid Therapeutics
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- (2017) Kazuhiko Haruta et al. Nucleic Acid Therapeutics
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- (2017) Irina V. Belyanina et al. Theranostics
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- (2017) George E. Maio et al. ChemistrySelect
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- (2016) Xin Li et al. Acta Biomaterialia
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- (2016) Amir Barzegar Behrooz et al. CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
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- (2016) Seyedeh Alia Moosavian et al. COLLOIDS AND SURFACES B-BIOINTERFACES
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- (2016) Morteza Azhdarzadeh et al. COLLOIDS AND SURFACES B-BIOINTERFACES
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- (2016) Xiaodong Xie et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
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- (2016) Seyed Mohammad Taghdisi et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
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- (2016) Sunday Shoyele et al. International Journal of Nanomedicine
- Specific targeting delivery to MUC1 overexpressing tumors by albumin-chitosan nanoparticles conjugated to DNA aptamer
- (2016) Mehdi Esfandyari-Manesh et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Pre-existing anti–polyethylene glycol antibody linked to first-exposure allergic reactions to pegnivacogin, a PEGylated RNA aptamer
- (2016) Nancy J. Ganson et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Enhancement of Thermal Damage to Adenocarcinoma Cells by Iron Nanoparticles Modified with MUC1 Aptamer
- (2016) Fangqin Guo et al. JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
- Double targeting, controlled release and reversible delivery of daunorubicin to cancer cells by polyvalent aptamers-modified gold nanoparticles
- (2016) Seyed Mohammad Taghdisi et al. Materials Science & Engineering C-Materials for Biological Applications
- Multivalent Aptamers: Versatile Tools for Diagnostic and Therapeutic Applications
- (2016) Mariya Vorobyeva et al. MOLECULES
- Methods for Improving Aptamer Binding Affinity
- (2016) Hijiri Hasegawa et al. MOLECULES
- Versatile surface engineering of porous nanomaterials with bioinspired polyphenol coatings for targeted and controlled drug delivery
- (2016) Juan Li et al. Nanoscale
- Tumor cell-specific photothermal killing by SELEX-derived DNA aptamer-targeted gold nanorods
- (2016) Ramya Chandrasekaran et al. Nanoscale
- Laboratory evolution of artificially expanded DNA gives redesignable aptamers that target the toxic form of anthrax protective antigen
- (2016) Elisa Biondi et al. NUCLEIC ACIDS RESEARCH
- Evoking picomolar binding in RNA by a single phosphorodithioate linkage
- (2016) N. Dinuka Abeydeera et al. NUCLEIC ACIDS RESEARCH
- Highly sensitive detection of leukemia cells based on aptamer and quantum dots
- (2016) Yating Yu et al. ONCOLOGY REPORTS
- 2′Fluoro Modification Differentially Modulates the Ability of RNAs to Activate Pattern Recognition Receptors
- (2016) Youngju Lee et al. Nucleic Acid Therapeutics
- Polydopamine-Based Surface Modification of Novel Nanoparticle-Aptamer Bioconjugates for In Vivo Breast Cancer Targeting and Enhanced Therapeutic Effects
- (2016) Wei Tao et al. Theranostics
- Photothermal Therapeutic Response of Cancer Cells to Aptamer–Gold Nanoparticle-Hybridized Graphene Oxide under NIR Illumination
- (2015) Lingyan Yang et al. ACS Applied Materials & Interfaces
- Specific aptamer-conjugated mesoporous silica–carbon nanoparticles for HER2-targeted chemo-photothermal combined therapy
- (2015) Kaiyuan Wang et al. Acta Biomaterialia
- Aptamer-Modified Temperature-Sensitive Liposomal Contrast Agent for Magnetic Resonance Imaging
- (2015) Kunchi Zhang et al. BIOMACROMOLECULES
- Current approaches in SELEX: An update to aptamer selection technology
- (2015) Mariia Darmostuk et al. BIOTECHNOLOGY ADVANCES
- Aptamer decorated hyaluronan/chitosan nanoparticles for targeted delivery of 5-fluorouracil to MUC1 overexpressing adenocarcinomas
- (2015) Zahra Ghasemi et al. CARBOHYDRATE POLYMERS
- Targeted and controlled release delivery of daunorubicin to T-cell acute lymphoblastic leukemia by aptamer-modified gold nanoparticles
- (2015) Noor Mohammad Danesh et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Epithelial cell adhesion molecule aptamer conjugated PEG–PLGA nanopolymersomes for targeted delivery of doxorubicin to human breast adenocarcinoma cell line in vitro
- (2015) Mona Alibolandi et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- An AS1411 aptamer-conjugated liposomal system containing a bubble-generating agent for tumor-specific chemotherapy that overcomes multidrug resistance
- (2015) Zi-Xian Liao et al. JOURNAL OF CONTROLLED RELEASE
- Thioaptamer-conjugated CD44-targeted delivery system for the treatment of breast cancer in vitro and in vivo
- (2015) Wei Fan et al. JOURNAL OF DRUG TARGETING
- Carbodiimide Induced Cross-Linking, Ligand Addition, and Degradation in Gelatin
- (2015) Christopher R. Cammarata et al. MOLECULAR PHARMACEUTICS
- Generation of Aptamers with an Expanded Chemical Repertoire
- (2015) Stella Diafa et al. MOLECULES
- Nucleolin targeting AS1411 aptamer modified pH-sensitive micelles for enhanced delivery and antitumor efficacy of paclitaxel
- (2015) Jinming Zhang et al. Nano Research
- Multifunctional nanoparticle–EpCAM aptamer bioconjugates: A paradigm for targeted drug delivery and imaging in cancer therapy
- (2015) Manasi Das et al. Nanomedicine-Nanotechnology Biology and Medicine
- Targeted delivery of anticancer drugs by aptamer AS1411 mediated Pluronic F127/cyclodextrin-linked polymer composite micelles
- (2015) Xin Li et al. Nanomedicine-Nanotechnology Biology and Medicine
- Targeted delivery of doxorubicin to breast cancer cells by aptamer functionalized DOTAP/DOPE liposomes
- (2015) XINGLI SONG et al. ONCOLOGY REPORTS
- Large-scale serum protein biomarker discovery in Duchenne muscular dystrophy
- (2015) Yetrib Hathout et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Screening and Identifying a Novel ssDNA Aptamer against Alpha-fetoprotein Using CE-SELEX
- (2015) Lili Dong et al. Scientific Reports
- A Controllable Aptamer-Based Self-Assembled DNA Dendrimer for High Affinity Targeting, Bioimaging and Drug Delivery
- (2015) Huimin Zhang et al. Scientific Reports
- Aptamer-Mediated Up-conversion Core/MOF Shell Nanocomposites for Targeted Drug Delivery and Cell Imaging
- (2015) Kerong Deng et al. Scientific Reports
- Targeting the PD-1/PD-L1 Immune Evasion Axis With DNA Aptamers as a Novel Therapeutic Strategy for the Treatment of Disseminated Cancers
- (2015) Aaron Prodeus et al. Molecular Therapy-Nucleic Acids
- Pharmacokinetics of a Cholesterol-conjugated Aptamer Against the Hepatitis C Virus (HCV) NS5B Protein
- (2015) Chang Ho Lee et al. Molecular Therapy-Nucleic Acids
- Thioaptamer Conjugated Liposomes for Tumor Vasculature Targeting
- (2015) Aman P. Mann et al. Oncotarget
- Aptamer-Functionalized Gold Nanoparticles As Photoresponsive Nanoplatform for Co-Drug Delivery
- (2014) Yi-Syun Shiao et al. ACS Applied Materials & Interfaces
- A novel aptamer functionalized CuInS2 quantum dots probe for daunorubicin sensing and near infrared imaging of prostate cancer cells
- (2014) Zihan Lin et al. ANALYTICA CHIMICA ACTA
- Locked nucleic acid/DNA chimeric aptamer probe for tumor diagnosis with improved serum stability and extended imaging window in vivo
- (2014) Hui Shi et al. ANALYTICA CHIMICA ACTA
- Gadolinium Oxide Nanoparticles and Aptamer-Functionalized Silver Nanoclusters-Based Multimodal Molecular Imaging Nanoprobe for Optical/Magnetic Resonance Cancer Cell Imaging
- (2014) Jingjing Li et al. ANALYTICAL CHEMISTRY
- Thioaptamers targeting dengue virus type-2 envelope protein domain III
- (2014) Sai Hari A. Gandham et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Functionalizing Liposomes with anti-CD44 Aptamer for Selective Targeting of Cancer Cells
- (2014) Walhan Alshaer et al. BIOCONJUGATE CHEMISTRY
- Synthesis and Self-Assembly of Amphiphilic Aptamer-Functionalized Hyperbranched Multiarm Copolymers for Targeted Cancer Imaging
- (2014) Songrui Yu et al. BIOMACROMOLECULES
- An aptamer ligand based liposomal nanocarrier system that targets tumor endothelial cells
- (2014) Mst. Naznin Ara et al. BIOMATERIALS
- Nucleolin-targeting liposomes guided by aptamer AS1411 for the delivery of siRNA for the treatment of malignant melanomas
- (2014) Liyu Li et al. BIOMATERIALS
- Aptamer CaCO3Nanostructures: A Facile, pH-Responsive, Specific Platform for Targeted Anticancer Theranostics
- (2014) Cuisong Zhou et al. Chemistry-An Asian Journal
- Efficient delivery of micro RNA to bone-metastatic prostate tumors by using aptamer-conjugated atelocollagenin vitroandin vivo
- (2014) Zhao Hao et al. DRUG DELIVERY
- Smart magnetic nanoparticle-aptamer probe for targeted imaging and treatment of hepatocellular carcinoma
- (2014) Chalermchai Pilapong et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- MUC1 aptamer conjugated to chitosan nanoparticles, an efficient targeted carrier designed for anticancer SN38 delivery
- (2014) E. Sayari et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Chemically Modified DNA Aptamers Bind Interleukin-6 with High Affinity and Inhibit Signaling by Blocking Its Interaction with Interleukin-6 Receptor
- (2014) Shashi Gupta et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- RNA aptamer-conjugated liposome as an efficient anticancer drug delivery vehicle targeting cancer cells in vivo
- (2014) Si Eun Baek et al. JOURNAL OF CONTROLLED RELEASE
- Synthesis of Base-Modified 2′-Deoxyribonucleoside Triphosphates and Their Use in Enzymatic Synthesis of Modified DNA for Applications in Bioanalysis and Chemical Biology
- (2014) Michal Hocek JOURNAL OF ORGANIC CHEMISTRY
- High Temperature SELMA: Evolution of DNA-Supported Oligomannose Clusters Which Are Tightly Recognized by HIV bnAb 2G12
- (2014) J. Sebastian Temme et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Synthetic Aptamer-Polymer Hybrid Constructs for Programmed Drug Delivery into Specific Target Cells
- (2014) Seung Soo Oh et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Grafting Aptamers onto Gold Nanostars Increases in Vitro Efficacy in a Wide Range of Cancer Cell Types
- (2014) Duncan Hieu M. Dam et al. MOLECULAR PHARMACEUTICS
- Aptamer-Targeted DNA Nanostructures for Therapeutic Delivery
- (2014) Phapanin Charoenphol et al. MOLECULAR PHARMACEUTICS
- Sequence motifs associated with hepatotoxicity of locked nucleic acid—modified antisense oligonucleotides
- (2014) Andrew D. Burdick et al. NUCLEIC ACIDS RESEARCH
- Targeted and ultrasound-triggered drug delivery using liposomes co-modified with cancer cell-targeting aptamers and a thermosensitive polymer
- (2014) Kazuaki Ninomiya et al. ULTRASONICS SONOCHEMISTRY
- Quantifying thiol–gold interactions towards the efficient strength control
- (2014) Yurui Xue et al. Nature Communications
- Nucleic Acid Ligands With Protein-like Side Chains: Modified Aptamers and Their Use as Diagnostic and Therapeutic Agents
- (2014) John C Rohloff et al. Molecular Therapy-Nucleic Acids
- Selection of 2′F-modified RNA aptamers against prostate-specific antigen and their evaluation for diagnostic and therapeutic applications
- (2013) M. Svobodova et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
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- (2013) Cuiling Zhang et al. ANALYTICAL CHEMISTRY
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- (2013) Zhiqing Zhang et al. BIOMATERIALS
- Aptamer-conjugated and doxorubicin-loaded unimolecular micelles for targeted therapy of prostate cancer
- (2013) Wenjin Xu et al. BIOMATERIALS
- The Spiegelmer NOX-A12, a novel CXCL12 inhibitor, interferes with chronic lymphocytic leukemia cell motility and causes chemosensitization
- (2013) J. Hoellenriegel et al. BLOOD
- Directed Evolution of 2G12-Targeted Nonamannose Glycoclusters by SELMA
- (2013) J. Sebastian Temme et al. CHEMISTRY-A EUROPEAN JOURNAL
- Synthesis, characterization and in vitro activity of thrombin-binding DNA aptamers with triazole internucleotide linkages
- (2013) Anna M. Varizhuk et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Tumor-specific hyperthermia with aptamer-tagged superparamagnetic nanoparticles
- (2013) Katarzyna Pala et al. International Journal of Nanomedicine
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- (2013) Axel Vater et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2013) A. Bandekar et al. JOURNAL OF NUCLEAR MEDICINE
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- (2013) Anna M. Varizhuk et al. JOURNAL OF ORGANIC CHEMISTRY
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- (2013) Yuri Imaizumi et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
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- (2013) Jonathan T. Sczepanski et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
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- (2013) N. van Bel et al. JOURNAL OF VIROLOGY
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- (2013) Michiko Kimoto et al. NATURE BIOTECHNOLOGY
- Potential Capacity of Aptamers to Trigger Immune Activation in Human Blood
- (2013) Meltem Avci-Adali et al. PLoS One
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- (2013) K. Sefah et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- In Vitro Selection of Modified RNA Aptamers Against CD44 Cancer Stem Cell Marker
- (2013) Nidaa Ababneh et al. Nucleic Acid Therapeutics
- Selective delivery of an anticancer drug with aptamer-functionalized liposomes to breast cancer cells in vitro and in vivo
- (2013) Hang Xing et al. Journal of Materials Chemistry B
- In vivo SELEX for Identification of Brain-penetrating Aptamers
- (2013) Congsheng Cheng et al. Molecular Therapy-Nucleic Acids
- Click Nucleic Acid Ligation: Applications in Biology and Nanotechnology
- (2012) Afaf H. El-Sagheer et al. ACCOUNTS OF CHEMICAL RESEARCH
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- (2012) Zhen Fan et al. ACS Nano
- Assembly of Aptamer Switch Probes and Photosensitizer on Gold Nanorods for Targeted Photothermal and Photodynamic Cancer Therapy
- (2012) Jian Wang et al. ACS Nano
- Engineering of Targeted Nanoparticles for Cancer Therapy Using Internalizing Aptamers Isolated by Cell-Uptake Selection
- (2012) Zeyu Xiao et al. ACS Nano
- Near-Infrared Light-Triggered, Targeted Drug Delivery to Cancer Cells by Aptamer Gated Nanovehicles
- (2012) Xinjian Yang et al. ADVANCED MATERIALS
- X-Aptamers: A Bead-Based Selection Method for Random Incorporation of Druglike Moieties onto Next-Generation Aptamers for Enhanced Binding
- (2012) Weiguo He et al. BIOCHEMISTRY
- PEGylation and Biodistribution of an anti-MUC1 Aptamer in MCF-7 Tumor-Bearing Mice
- (2012) Chiara Da Pieve et al. BIOCONJUGATE CHEMISTRY
- Aptamer-Capped Multifunctional Mesoporous Strontium Hydroxyapatite Nanovehicle for Cancer-Cell-Responsive Drug Delivery and Imaging
- (2012) Zhenhua Li et al. BIOMACROMOLECULES
- MUC-1 aptamer-conjugated dye-doped silica nanoparticles for MCF-7 cells detection
- (2012) Li Cai et al. BIOMATERIALS
- AS1411 aptamer tagged PLGA-lecithin-PEG nanoparticles for tumor cell targeting and drug delivery
- (2012) Athulya Aravind et al. BIOTECHNOLOGY AND BIOENGINEERING
- Synthesis of Deoxynucleoside Triphosphates that Include Proline, Urea, or Sulfonamide Groups and Their Polymerase Incorporation into DNA
- (2012) Marcel Hollenstein CHEMISTRY-A EUROPEAN JOURNAL
- Instantaneous and Quantitative Functionalization of Gold Nanoparticles with Thiolated DNA Using a pH-Assisted and Surfactant-Free Route
- (2012) Xu Zhang et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Aptamers and the next generation of diagnostic reagents
- (2012) Varatharasa Thiviyanathan et al. Proteomics Clinical Applications
- Dressed for success – applying chemistry to modulate aptamer functionality
- (2012) Fabian Tolle et al. Chemical Science
- Polyvalent Mesoporous Silica Nanoparticle-Aptamer Bioconjugates Target Breast Cancer Cells
- (2012) Le-Le Li et al. Advanced Healthcare Materials
- Smart Multifunctional Nanostructure for Targeted Cancer Chemotherapy and Magnetic Resonance Imaging
- (2011) Tao Chen et al. ACS Nano
- Aptamer-Conjugated DNA Icosahedral Nanoparticles As a Carrier of Doxorubicin for Cancer Therapy
- (2011) Microsugar Chang et al. ACS Nano
- Release of Photoactivatable Drugs from Plasmonic Nanoparticles for Targeted Cancer Therapy
- (2011) Yun-Ling Luo et al. ACS Nano
- Incorporation of a decorin biomimetic enhances the mechanical properties of electrochemically aligned collagen threads
- (2011) Vipuil Kishore et al. Acta Biomaterialia
- Multivalent Glycocluster Design through Directed Evolution
- (2011) Iain S. MacPherson et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Aptamer-functionalized PEG–PLGA nanoparticles for enhanced anti-glioma drug delivery
- (2011) Jianwei Guo et al. BIOMATERIALS
- Aptamer-conjugated and drug-loaded acoustic droplets for ultrasound theranosis
- (2011) Chung-Hsin Wang et al. BIOMATERIALS
- Synthesis and properties of triazole-linked RNA
- (2011) Daniel Mutisya et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Aptamer ARC19499 mediates a procoagulant hemostatic effect by inhibiting tissue factor pathway inhibitor
- (2011) E. K. Waters et al. BLOOD
- Enzymatic Recognition of 2′-Modified Ribonucleoside 5′-Triphosphates: Towards the Evolution of Versatile Aptamers
- (2011) Lasse H. Lauridsen et al. CHEMBIOCHEM
- Immobilization-free screening of aptamers assisted by graphene oxide
- (2011) Jee-Woong Park et al. CHEMICAL COMMUNICATIONS
- Locked vs. unlocked nucleic acids (LNA vs. UNA): contrasting structures work towards common therapeutic goals
- (2011) Meghan A. Campbell et al. CHEMICAL SOCIETY REVIEWS
- Nucleic Acid Aptamers: Clinical Applications and Promising New Horizons
- (2011) X. Ni et al. CURRENT MEDICINAL CHEMISTRY
- Self-assemble gene delivery system for molecular targeting using nucleic acid aptamer
- (2011) Tomoaki Kurosaki et al. GENE
- Targeted chemoimmunotherapy using drug-loaded aptamer–dendrimer bioconjugates
- (2011) In-Hyun Lee et al. JOURNAL OF CONTROLLED RELEASE
- Tumor targeted quantum dot-mucin 1 aptamer-doxorubicin conjugate for imaging and treatment of cancer
- (2011) Ronak Savla et al. JOURNAL OF CONTROLLED RELEASE
- C2′-Pyrene-Functionalized Triazole-Linked DNA: Universal DNA/RNA Hybridization Probes
- (2011) Sujay P. Sau et al. JOURNAL OF ORGANIC CHEMISTRY
- PEGylated Anti-MUC1 Aptamer-Doxorubicin Complex for Targeted Drug Delivery to MCF7 Breast Cancer Cells
- (2011) Lihan Tan et al. MACROMOLECULAR BIOSCIENCE
- Inhibition of Cell Proliferation by an Anti-EGFR Aptamer
- (2011) Na Li et al. PLoS One
- A Neutralizing RNA Aptamer against EGFR Causes Selective Apoptotic Cell Death
- (2011) Carla Lucia Esposito et al. PLoS One
- Novel Aptamer-Nanoparticle Bioconjugates Enhances Delivery of Anticancer Drug to MUC1-Positive Cancer Cells In Vitro
- (2011) Chenchen Yu et al. PLoS One
- Image-Guided Prostate Cancer Therapy Using Aptamer-Functionalized Thermally Cross-Linked Superparamagnetic Iron Oxide Nanoparticles
- (2011) Mi Kyung Yu et al. Small
- A nanocomplex that is both tumor cell-selective and cancer gene-specific for anaplastic large cell lymphoma
- (2011) Nianxi Zhao et al. JOURNAL OF NANOBIOTECHNOLOGY
- Dual-Surface Modified Virus Capsids for Targeted Delivery of Photodynamic Agents to Cancer Cells
- (2010) Nicholas Stephanopoulos et al. ACS Nano
- Combinatorial Selection of DNA Thioaptamers Targeted to the HA Binding Domain of Human CD44
- (2010) Anoma Somasunderam et al. BIOCHEMISTRY
- A Temperature-Responsive Antibody-Like Nanostructure
- (2010) Jing Zhou et al. BIOMACROMOLECULES
- The formulation of aptamer-coated paclitaxel–polylactide nanoconjugates and their targeting to cancer cells
- (2010) Rong Tong et al. BIOMATERIALS
- Anticoagulant Effects of Thioanalogs of Thrombin-Binding DNA-Aptamer and Their Stability in the Plasma
- (2010) G. E. Pozmogova et al. BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE
- Click chemistry with DNA
- (2010) Afaf H. El-Sagheer et al. CHEMICAL SOCIETY REVIEWS
- Reversible Targeting and controlled release delivery of daunorubicin to cancer cells by aptamer-wrapped carbon nanotubes
- (2010) Seyed Mohammad Taghdisi et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Lipophilicity in drug discovery
- (2010) Michael J Waring Expert Opinion on Drug Discovery
- Bioimaging of Nucleolin Aptamer-Containing 5-(N-benzylcarboxyamide)-2′-deoxyuridine More Capable of Specific Binding to Targets in Cancer Cells
- (2010) Kyue Yim Lee et al. JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY
- Expanding the Chemistry of DNA for in Vitro Selection
- (2010) Jonathan D. Vaught et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Molecular Evolution of Functional Nucleic Acids with Chemical Modifications
- (2010) Masayasu Kuwahara et al. MOLECULES
- Improved thrombin binding aptamer by incorporation of a single unlocked nucleic acid monomer
- (2010) Anna Pasternak et al. NUCLEIC ACIDS RESEARCH
- Differential stability of 2′F-ANA•RNA and ANA•RNA hybrid duplexes: roles of structure, pseudohydrogen bonding, hydration, ion uptake and flexibility
- (2010) Jonathan K. Watts et al. NUCLEIC ACIDS RESEARCH
- Identification of Thioaptamer Ligand against E-Selectin: Potential Application for Inflamed Vasculature Targeting
- (2010) Aman P. Mann et al. PLoS One
- Synthesis of Readily Accessible Triazole-Linked Dimer Deoxynucleoside Phosphoramidite for Solid-Phase Oligonucleotide Synthesis
- (2010) Srivari Chandrasekhar et al. SYNTHESIS-STUTTGART
- Reversible Cell-Specific Drug Delivery with Aptamer-Functionalized Liposomes
- (2009) Zehui Cao et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Aptamers as a model for functional evaluation of LNA and 2′-amino LNA
- (2009) Frank J. Hernandez et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Conformation and thermostability of oligonucleotide d(GGTTGGTGTGGTTGG) containing thiophosphoryl internucleotide bonds at different positions
- (2009) Marina Zaitseva et al. BIOPHYSICAL CHEMISTRY
- A liposome-based nanostructure for aptamer directed delivery
- (2009) Huaizhi Kang et al. CHEMICAL COMMUNICATIONS
- Identification of an aptamer targeting hnRNP A1 by tissue slide‐based SELEX
- (2009) Shaohua Li et al. JOURNAL OF PATHOLOGY
- Efficient enzymatic synthesis of LNA-modified DNA duplexes using KOD DNA polymerase
- (2009) Rakesh N. Veedu et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Studies on the hydrolytic stability of 2′-fluoroarabinonucleic acid (2′F-ANA)
- (2009) Jonathan K. Watts et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- DNA aptamer-micelle as an efficient detection/delivery vehicle toward cancer cells
- (2009) Y. Wu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cancer Cell Targeting Using Multiple Aptamers Conjugated on Nanorods
- (2008) Yu-Fen Huang et al. ANALYTICAL CHEMISTRY
- Arginine-modified DNA Aptamers That Show Enantioselective Recognition of the Dicarboxylic Acid Moiety of Glutamic Acid
- (2008) Kazuomi OHSAWA et al. ANALYTICAL SCIENCES
- Investigations toward the selection of fully-modified 4′-thioRNA aptamers: Optimization of in vitro transcription steps in the presence of 4′-thioNTPs
- (2008) Noriaki Minakawa et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Selection of DNA aptamers against VEGF165 using a protein competitor and the aptamer blotting method
- (2008) Hijiri Hasegawa et al. BIOTECHNOLOGY LETTERS
- Differential Inhibitory Activities and Stabilisation of DNA Aptamers against the SARS Coronavirus Helicase
- (2008) Ka To Shum et al. CHEMBIOCHEM
- Oxidative coupling of peptides to a virus capsid containing unnatural amino acids
- (2008) Zachary M. Carrico et al. CHEMICAL COMMUNICATIONS
- Selecting Aptamers for a Glycoprotein through the Incorporation of the Boronic Acid Moiety
- (2008) Minyong Li et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Selective Photothermal Therapy for Mixed Cancer Cells Using Aptamer-Conjugated Nanorods
- (2008) Yu-Fen Huang et al. LANGMUIR
- Quantum dot-labeled aptamer nanoprobes specifically targeting glioma cells
- (2008) Xue-Chai Chen et al. NANOTECHNOLOGY
- Targeted delivery of cisplatin to prostate cancer cells by aptamer functionalized Pt(IV) prodrug-PLGA-PEG nanoparticles
- (2008) S. Dhar et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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