Single-cell RNA sequencing of mouse islets exposed to proinflammatory cytokines

SurfaceGenie: a web-based application for prioritizing cell-type specific marker candidates

(2020) Matthew Waas et al.   BIOINFORMATICS

Pancreatic β-cells in type 1 and type 2 diabetes mellitus: different pathways to failure

(2020) Décio L. Eizirik et al.   Nature Reviews Endocrinology

Inhibition of mitochondrial oxidative metabolism attenuates EMCV replication and protects β-cells from virally mediated lysis

(2020) Joshua D Stafford et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Guanylate-Binding Proteins 2 and 5 Exert Broad Antiviral Activity by Inhibiting Furin-Mediated Processing of Viral Envelope Proteins

(2019) Elisabeth Braun et al.   Cell Reports

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

The Role of Inflammation in β-cell Dedifferentiation

(2017) Thierry M. Nordmann et al.   Scientific Reports

Pancreatic β-Cells Express the Fetal Islet Hormone Gastrin in Rodent and Human Diabetes

(2016) Tehila Dahan et al.   DIABETES

Nitric Oxide Suppresses β-Cell Apoptosis by Inhibiting the DNA Damage Response

(2016) Bryndon J. Oleson et al.   MOLECULAR AND CELLULAR BIOLOGY

Identification of proliferative and mature β-cells in the islets of Langerhans

(2016) Erik Bader et al.   NATURE

Aldehyde dehydrogenase 1a3 defines a subset of failing pancreatic β cells in diabetic mice

(2016) Ja Young Kim-Muller et al.   Nature Communications

Human islets contain four distinct subtypes of β cells

(2016) Craig Dorrell et al.   Nature Communications

Interferon-Stimulated Genes: A Complex Web of Host Defenses

(2014) William M. Schneider et al.   Annual Review of Immunology

Pdx1 Maintains β Cell Identity and Function by Repressing an α Cell Program

(2014) Tao Gao et al.   Cell Metabolism

The diabetes gene Hhex maintains  -cell differentiation and islet function

(2014) J. Zhang et al.   GENES & DEVELOPMENT

Antiviral Activity of Human OASL Protein Is Mediated by Enhancing Signaling of the RIG-I RNA Sensor

(2014) Jianzhong Zhu et al.   IMMUNITY

Differential responses of pancreatic β-cells to ROS and RNS

(2013) Gordon P. Meares et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The role of reactive oxygen species and proinflammatory cytokines in type 1 diabetes pathogenesis

(2013) Lindsey E. Padgett et al.   Annals of the New York Academy of Sciences

Pancreatic α-Cell Specific Deletion of Mouse Arx Leads to α-Cell Identity Loss

(2013) Crystal L. Wilcox et al.   PLoS One

Pancreatic β Cell Dedifferentiation as a Mechanism of Diabetic β Cell Failure

(2012) Chutima Talchai et al.   CELL

ß-Defensins: Multifunctional Modulators of Infection, Inflammation and More?

(2012) Fiona Semple et al.   Journal of Innate Immunity

Functional beta-cell maturation is marked by an increased glucose threshold and by expression of urocortin 3

(2012) Barak Blum et al.   NATURE BIOTECHNOLOGY

FoxO1 and SIRT1 Regulate β-Cell Responses to Nitric Oxide

(2011) Katherine J. Hughes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cytokines Interleukin-1  and Tumor Necrosis Factor-  Regulate Different Transcriptional and Alternative Splicing Networks in Primary  -Cells

(2009) F. Ortis et al.   DIABETES

Proinflammatory Cytokines Activate the Intrinsic Apoptotic Pathway in  -Cells

(2009) L. G. Grunnet et al.   DIABETES