Aldehyde dehydrogenase 1a3 defines a subset of failing pancreatic β cells in diabetic mice

Altered Plasma Profile of Antioxidant Proteins as an Early Correlate of Pancreatic β Cell Dysfunction

(2016) Taiyi Kuo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FoxO1 Deacetylation Decreases Fatty Acid Oxidation in β-Cells and Sustains Insulin Secretion in Diabetes

(2016) Ja Young Kim-Muller et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evidence of β-Cell Dedifferentiation in Human Type 2 Diabetes

(2016) Francesca Cinti et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

N,N-diethylaminobenzaldehyde (DEAB) as a substrate and mechanism-based inhibitor for human ALDH isoenzymes

(2015) Cynthia A. Morgan et al.   CHEMICO-BIOLOGICAL INTERACTIONS

A Mutant Allele Encoding DNA Binding–Deficient FoxO1 Differentially Regulates Hepatic Glucose and Lipid Metabolism

(2015) Joshua R. Cook et al.   DIABETES

Legacy Effect of Foxo1 in Pancreatic Endocrine Progenitors on Adult β-Cell Mass and Function

(2015) Shivatra Chutima Talchai et al.   DIABETES

The new biology of diabetes

(2015) Utpal B. Pajvani et al.   DIABETOLOGIA

Retinoic acid receptor signaling is required to maintain glucose-stimulated insulin secretion and β-cell mass

(2015) Pierre-Jacques Brun et al.   FASEB JOURNAL

The emerging role of Nrf2 in mitochondrial function

(2015) Albena T. Dinkova-Kostova et al.   FREE RADICAL BIOLOGY AND MEDICINE

ALDH1A3: A Marker of Mesenchymal Phenotype in Gliomas Associated with Cell Invasion

(2015) Wenlong Zhang et al.   PLoS One

Membrane-Bound CYB5R3 Is a Common Effector of Nutritional and Oxidative Stress Response Through FOXO3a and Nrf2

(2014) Emilio Siendones et al.   ANTIOXIDANTS & REDOX SIGNALING

Ablation of Elovl6 protects pancreatic islets from high-fat diet-induced impairment of insulin secretion

(2014) Nie Tang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Metabolic Inflexibility Impairs Insulin Secretion and Results In MODY-like Diabetes in Triple FoxO-Deficient Mice

(2014) Ja Young Kim-Muller et al.   Cell Metabolism

Pancreatic β Cell Dedifferentiation in Diabetes and Redifferentiation following Insulin Therapy

(2014) Zhiyu Wang et al.   Cell Metabolism

Epigenetic Regulation of the DLK1-MEG3 MicroRNA Cluster in Human Type 2 Diabetic Islets

(2014) Vasumathi Kameswaran et al.   Cell Metabolism

BACH2, a Candidate Risk Gene for Type 1 Diabetes, Regulates Apoptosis in Pancreatic  -Cells via JNK1 Modulation and Crosstalk With the Candidate Gene PTPN2

(2014) L. Marroqui et al.   DIABETES

The MafA Transcription Factor Becomes Essential to Islet β-Cells Soon After Birth

(2014) Yan Hang et al.   DIABETES

Feature ranking of type 1 diabetes susceptibility genes improves prediction of type 1 diabetes

(2014) Christiane Winkler et al.   DIABETOLOGIA

Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants

(2014) Lorenzo Pasquali et al.   NATURE GENETICS

Nkx6.1 regulates islet  -cell proliferation via Nr4a1 and Nr4a3 nuclear receptors

(2014) J. S. Tessem et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism

(2014) J. Fadista et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metabolic Signaling in Fuel-Induced Insulin Secretion

(2013) Marc Prentki et al.   Cell Metabolism

Inactivation of specific β cell transcription factors in type 2 diabetes

(2013) Shuangli Guo et al.   JOURNAL OF CLINICAL INVESTIGATION

Nkx6.1 Is Essential for Maintaining the Functional State of Pancreatic Beta Cells

(2013) Brandon L. Taylor et al.   Cell Reports

ALDH marks leukemia stem cell

(2012) A. G. Fleischman   BLOOD

Brown Remodeling of White Adipose Tissue by SirT1-Dependent Deacetylation of Pparγ

(2012) Li Qiang et al.   CELL

Pancreatic β Cell Dedifferentiation as a Mechanism of Diabetic β Cell Failure

(2012) Chutima Talchai et al.   CELL

FoxOs Integrate Pleiotropic Actions of Insulin in Vascular Endothelium to Protect Mice from Atherosclerosis

(2012) Kyoichiro Tsuchiya et al.   Cell Metabolism

Human β Cell Transcriptome Analysis Uncovers lncRNAs That Are Tissue-Specific, Dynamically Regulated, and Abnormally Expressed in Type 2 Diabetes

(2012) Ignasi Morán et al.   Cell Metabolism

Generation of functional insulin-producing cells in the gut by Foxo1 ablation

(2012) Chutima Talchai et al.   NATURE GENETICS

Effects of vitamin D on antigen-specific and non-antigen-specific immune modulation: relevance for type 1 diabetes

(2012) Tatiana Takiishi et al.   PEDIATRIC DIABETES

Aldehyde dehydrogenase: Its role as a cancer stem cell marker comes down to the specific isoform

(2011) Paola Marcato et al.   CELL CYCLE

Diabetes in Mice With Selective Impairment of Insulin Action in Glut4-Expressing Tissues

(2011) Hua V. Lin et al.   DIABETES

Rictor/mTORC2 Is Essential for Maintaining a Balance Between β-Cell Proliferation and Cell Size

(2011) Yanyun Gu et al.   DIABETES

MODY

(2011) Stefan S. Fajans et al.   DIABETES CARE

Transcriptomes of the major human pancreatic cell types

(2011) C. Dorrell et al.   DIABETOLOGIA

Mitochondrial proteome analysis reveals altered expression of voltage dependent anion channels in pancreatic β-cells exposed to high glucose

(2011) Meftun Ahmed et al.   Islets

The Stunned β Cell: A Brief History

(2010) Ele Ferrannini   Cell Metabolism

High ALDH Activity Identifies Chemotherapy-Resistant Ewing's Sarcoma Stem Cells That Retain Sensitivity to EWS-FLI1 Inhibition

(2010) Ola Awad et al.   PLoS One

NQR1 controls lifespan by regulating the promotion of respiratory metabolism in yeast

(2009) María Jiménez-Hidalgo et al.   AGING CELL

Detailed transcriptome atlas of the pancreatic beta cell

(2009) Burak Kutlu et al.   BMC Medical Genomics

Aldehyde Dehydrogenase 1 Is a Marker for Normal and Malignant Human Colonic Stem Cells (SC) and Tracks SC Overpopulation during Colon Tumorigenesis

(2009) E. H. Huang et al.   CANCER RESEARCH

A GLI1-p53 inhibitory loop controls neural stem cell and tumour cell numbers

(2009) Barbara Stecca et al.   EMBO JOURNAL

Regulation of Pancreatic Juxtaductal Endocrine Cell Formation by FoxO1

(2009) T. Kitamura et al.   MOLECULAR AND CELLULAR BIOLOGY

The imprinted DLK1-MEG3 gene region on chromosome 14q32.2 alters susceptibility to type 1 diabetes

(2009) Chris Wallace et al.   NATURE GENETICS

High aldehyde dehydrogenase and expression of cancer stem cell markers selects for breast cancer cells with enhanced malignant and metastatic ability

(2008) Alysha K. Croker et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci

(2008) Jason D Cooper et al.   NATURE GENETICS

Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus

(2008) Kazuki Yasuda et al.   NATURE GENETICS