Pancreatic α-Cell Specific Deletion of Mouse Arx Leads to α-Cell Identity Loss

Epigenomic plasticity enables human pancreatic α to β cell reprogramming

(2013) Nuria C. Bramswig et al.   JOURNAL OF CLINICAL INVESTIGATION

Arx is required for normal enteroendocrine cell development in mice and humans

(2012) Aiping Du et al.   DEVELOPMENTAL BIOLOGY

Transcriptional regulation of α-cell differentiation

(2011) N. C. Bramswig et al.   DIABETES OBESITY & METABOLISM

Context-specific  -to- -cell reprogramming by forced Pdx1 expression

(2011) Y.-P. Yang et al.   GENES & DEVELOPMENT

β-cell replication and islet neogenesis following partial pancreatectomy

(2011) Seung-Hee Lee et al.   Islets

Regenerating pancreatic β-cells: plasticity of adult pancreatic cells and the feasibility of in-vivo neogenesis

(2010) Kirstine Juhl et al.   Current Opinion in Organ Transplantation

Partial loss of pancreas endocrine and exocrine cells of human ARX-null mutation: Consideration of pancreas differentiation

(2010) Masayuki Itoh et al.   DIFFERENTIATION

α Cell–Specific Men1 Ablation Triggers the Transdifferentiation of Glucagon-Expressing Cells and Insulinoma Development

(2010) Jieli Lu et al.   GASTROENTEROLOGY

Activation of pancreatic-duct-derived progenitor cells during pancreas regeneration in adult rats

(2010) W.-C. Li et al.   JOURNAL OF CELL SCIENCE

Glucagon Deficiency Reduces Hepatic Glucose Production and Improves Glucose Tolerance In Adult Mice

(2010) Aidan S. Hancock et al.   MOLECULAR ENDOCRINOLOGY

Conversion of adult pancreatic α-cells to β-cells after extreme β-cell loss

(2010) Fabrizio Thorel et al.   NATURE

The Ectopic Expression of Pax4 in the Mouse Pancreas Converts Progenitor Cells into α and Subsequently β Cells

(2009) Patrick Collombat et al.   CELL

How to make β cells?

(2009) Malgorzata Borowiak et al.   CURRENT OPINION IN CELL BIOLOGY

Identification of Arx transcriptional targets in the developing basal forebrain

(2008) Carl T. Fulp et al.   HUMAN MOLECULAR GENETICS