ß-Defensins: Multifunctional Modulators of Infection, Inflammation and More?

Low Molecular Weight Hyaluronic Acid Increases the Self-Defense of Skin Epithelium by Induction of  -Defensin 2 via TLR2 and TLR4

(2014) S. Gariboldi et al.   JOURNAL OF IMMUNOLOGY

Human Beta-Defensin-1, -2, and -3 Exhibit Opposite Effects on Oral Squamous Cell Carcinoma Cell Proliferation

(2011) Jochen Winter et al.   CANCER INVESTIGATION

Human β-defensin 3 affects the activity of pro-inflammatory pathways associated with MyD88 and TRIF

(2011) Fiona Semple et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The Toll-like receptor 1/2 agonists Pam3CSK4 and human β-defensin-3 differentially induce interleukin-10 and nuclear factor-κB signalling patterns in human monocytes

(2011) Nicholas T. Funderburg et al.   IMMUNOLOGY

Induction of Regulatory T Cells by a Murine  -Defensin

(2011) F. Navid et al.   JOURNAL OF IMMUNOLOGY

Modulation of human β-defensin-1 (hBD-1) in plasmacytoid dendritic cells (PDC), monocytes, and epithelial cells by influenza virus, Herpes simplex virus, and Sendai virus and its possible role in innate immunity

(2011) Lisa K. Ryan et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Reduction of disulphide bonds unmasks potent antimicrobial activity of human β-defensin 1

(2011) Bjoern O. Schroeder et al.   NATURE

A Common Mutation in the Defensin DEFB126 Causes Impaired Sperm Function and Subfertility

(2011) T. L. Tollner et al.   Science Translational Medicine

Interaction of Human β-Defensin 2 (HBD2) with Glycosaminoglycans

(2010) Emily S. Seo et al.   BIOCHEMISTRY

Lipopolysaccharide-Induced Epididymitis Disrupts Epididymal Beta-Defensin Expression and Inhibits Sperm Motility in Rats1

(2010) Dongmei Cao et al.   BIOLOGY OF REPRODUCTION

Topographical distribution of antimicrobial genes in the zebrafish intestine

(2010) Stefan H. Oehlers et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Human β-defensin 3 has immunosuppressive activityin vitroandin vivo

(2010) Fiona Semple et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Measurement methods and accuracy in copy number variation: failure to replicate associations of beta-defensin copy number with Crohn's disease

(2010) Marian C. Aldhous et al.   HUMAN MOLECULAR GENETICS

Human  -Defensin 3 Inhibits Cell Wall Biosynthesis in Staphylococci

(2010) V. Sass et al.   INFECTION AND IMMUNITY

The Antimicrobial Peptide DEFB1 Is Associated with Caries

(2010) A. Ozturk et al.   JOURNAL OF DENTAL RESEARCH

Human  -Defensin 2 and 3 and Their Mouse Orthologs Induce Chemotaxis through Interaction with CCR2

(2010) J. Rohrl et al.   JOURNAL OF IMMUNOLOGY

Antimicrobial Peptides Human  -Defensins and Cathelicidin LL-37 Induce the Secretion of a Pruritogenic Cytokine IL-31 by Human Mast Cells

(2010) F. Niyonsaba et al.   JOURNAL OF IMMUNOLOGY

An Antimicrobial Peptide Regulates Tumor-Associated Macrophage Trafficking via the Chemokine Receptor CCR2, a Model for Tumorigenesis

(2010) Ge Jin et al.   PLoS One

Peroxisome proliferator-activated receptor gamma activation is required for maintenance of innate antimicrobial immunity in the colon

(2010) L. Peyrin-Biroulet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Plectasin, a Fungal Defensin, Targets the Bacterial Cell Wall Precursor Lipid II

(2010) T. Schneider et al.   SCIENCE

Association of Higher DEFB4 Genomic Copy Number With Crohn's Disease

(2009) Robert W Bentley et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Expression Profile of Human Beta-Defensin 3 in Oral Squamous Cell Carcinoma

(2009) Marco Rainer Kesting et al.   CANCER INVESTIGATION

Defensin-related peptide 1 (Defr1) is allelic to Defb8 and chemoattracts immature DC and CD4+ T cells independently of CCR6

(2009) Karen Taylor et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Immunization with Bin1b decreases sperm motility with compromised fertility in rats

(2009) Wenming Xu et al.   FERTILITY AND STERILITY

CCR6 Regulation of the Actin Cytoskeleton Orchestrates Human Beta Defensin-2- and CCL20-mediated Restitution of Colonic Epithelial Cells

(2009) Rebecca A. Vongsa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human beta-defensin-3 promotes wound healing in infected diabetic wounds

(2009) Tobias Hirsch et al.   JOURNAL OF GENE MEDICINE

Dying and Necrotic Neutrophils Are Anti-Inflammatory Secondary to the Release of  -Defensins

(2009) K. Miles et al.   JOURNAL OF IMMUNOLOGY

Defensin-like polypeptide LUREs are pollen tube attractants secreted from synergid cells

(2009) Satohiro Okuda et al.   NATURE

EMAGE mouse embryo spatial gene expression database: 2010 update

(2009) Lorna Richardson et al.   NUCLEIC ACIDS RESEARCH

A defensin from tomato with dual function in defense and development

(2009) Henrik U. Stotz et al.   PLANT MOLECULAR BIOLOGY

β-Defensin-2 Protein Is a Serum Biomarker for Disease Activity in Psoriasis and Reaches Biologically Relevant Concentrations in Lesional Skin

(2009) Patrick A. M. Jansen et al.   PLoS One

Allelic recombination between distinct genomic locations generates copy number diversity in human β-defensins

(2009) Suhaili Abu Bakar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular and Evolutionary History of Melanism in North American Gray Wolves

(2009) T. M. Anderson et al.   SCIENCE

AMPed up immunity: how antimicrobial peptides have multiple roles in immune defense

(2009) Yuping Lai et al.   TRENDS IN IMMUNOLOGY

Loss of human β-defensin 1, 2, and 3 expression in oral squamous cell carcinoma

(2009) S. Joly et al.   Oral microbiology and immunology

Defensins and the convergent evolution of platypus and reptile venom genes

(2008) C. M. Whittington et al.   GENOME RESEARCH

Macaque sperm coating protein DEFB126 facilitates sperm penetration of cervical mucus

(2008) T. L. Tollner et al.   HUMAN REPRODUCTION

Human β-defensin 3 binds to hemagglutinin B (rHagB), a non-fimbrial adhesin from Porphyromonas gingivalis , and attenuates a pro-inflammatory cytokine response

(2008) Lindsey C Pingel et al.   IMMUNOLOGY AND CELL BIOLOGY

Evaluation of the effect of human  -defensins on neutrophil apoptosis

(2008) I. Nagaoka et al.   INTERNATIONAL IMMUNOLOGY

Analysis and Separation of Residues Important for the Chemoattractant and Antimicrobial Activities of β-Defensin 3

(2008) Karen Taylor et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Overexpression of human β-defensin-3 in oral dysplasia: Potential role in macrophage trafficking

(2008) Hameem I. Kawsar et al.   ORAL ONCOLOGY

Antimicrobial human beta-defensin-2 stimulates migration, proliferation and tube formation of human umbilical vein endothelial cells

(2008) Adone Baroni et al.   PEPTIDES

β-Defensin 22 is a major component of the mouse sperm glycocalyx

(2008) Ashley I Yudin et al.   REPRODUCTION

Expression patterns of platypus defensin and related venom genes across a range of tissue types reveal the possibility of broader functions for OvDLPs than previously suspected

(2008) Camilla M. Whittington et al.   TOXICON

Beta-Defensin 126 on the Surface of Macaque Sperm Mediates Attachment of Sperm to Oviductal Epithelia1

(2007) Theodore L. Tollner et al.   BIOLOGY OF REPRODUCTION

Functional analysis of the host defense peptide Human Beta Defensin-1: New insight into its potential role in cancer

(2007) Rebecca S. Bullard et al.   MOLECULAR IMMUNOLOGY

Clinicopathologic significance of tumor cell-lined vessel and microenvironment in oral squamous cell carcinoma

(2007) Shyun-Yeu Liu et al.   ORAL ONCOLOGY