High fat diet-induced brain damaging effects through autophagy-mediated senescence, inflammation and apoptosis mitigated by ginsenoside F1-enhanced mixture

Doxorubicin‐induced normal breast epithelial cellular aging and its related breast cancer growth through mitochondrial autophagy and oxidative stress mitigated by ginsenoside Rh2

(2020) Jingang Hou et al.   PHYTOTHERAPY RESEARCH

NIA workshop on senescence in brain aging and Alzheimer’s disease and its related dementias

(2020) Amanda M. DiBattista et al.   GeroScience

Implicating endothelial cell senescence to dysfunction in the ageing and diseased brain

(2020) Sara I. Graves et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Roles of Telomere Biology in Cell Senescence, Replicative and Chronological Ageing

(2019) Jun Liu et al.   Cells

Minor ginsenoside F1 improves memory in APP/PS1 mice

(2019) Junho Han et al.   Molecular Brain

Cellular senescence in brain aging and neurodegenerative diseases: evidence and perspectives

(2018) Darren J. Baker et al.   JOURNAL OF CLINICAL INVESTIGATION

Ginseng and obesity

(2018) Zhipeng Li et al.   Journal of Ginseng Research

IL-1R signaling promotes STAT3 and NF-κB factor recruitment to distal cis-regulatory elements that regulateIl17a/ftranscription

(2018) Sarah K. Whitley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Life, death and autophagy

(2018) Johnna Doherty et al.   NATURE CELL BIOLOGY

Redox Balance, Antioxidant Defense, and Oxidative Damage in the Hypothalamus and Cerebral Cortex of Rats with High Fat Diet-Induced Insulin Resistance

(2018) Mateusz Maciejczyk et al.   Oxidative Medicine and Cellular Longevity

Suppressive effects of rare ginsenosides, Rk1 and Rg5, on HMGB1-mediated septic responses

(2018) Ji-Eun Kim et al.   FOOD AND CHEMICAL TOXICOLOGY

Ginsenoside Re Ameliorates Brain Insulin Resistance and Cognitive Dysfunction in High Fat Diet-Induced C57BL/6 Mice

(2017) Jong Min Kim et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Melatonin reverses H2 O2 -induced senescence in SH-SY5Y cells by enhancing autophagy via sirtuin 1 deacetylation of the RelA/p65 subunit of NF-κB

(2017) Chutikorn Nopparat et al.   JOURNAL OF PINEAL RESEARCH

Microglia activation triggers oligodendrocyte precursor cells apoptosis via HSP60

(2017) Yunhong Li et al.   Molecular Medicine Reports

Physiological Aging: Links Among Adipose Tissue Dysfunction, Diabetes, and Frailty

(2017) Michael B. Stout et al.   PHYSIOLOGY

Mitochondrial – Endoplasmic reticulum interactions in the trophoblast: Stress and senescence

(2017) G.J. Burton et al.   PLACENTA

NEMO Links Nuclear Factor-κB to Human Diseases

(2017) Gunter Maubach et al.   TRENDS IN MOLECULAR MEDICINE

Mitochondria in Cell Senescence: Is Mitophagy the Weakest Link?

(2017) Viktor I. Korolchuk et al.   EBioMedicine

Omega-3 PUFA modulate lipogenesis, ER stress, and mitochondrial dysfunction markers in NASH – Proteomic and lipidomic insight

(2017) Lívia Samara dos Reis Rodrigues Okada et al.   CLINICAL NUTRITION

Dietary obesity reversibly induces synaptic stripping by microglia and impairs hippocampal plasticity

(2016) Shuai Hao et al.   BRAIN BEHAVIOR AND IMMUNITY

Regarding Obesity as a Disease

(2016) Theodore K. Kyle et al.   ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA

High fat induces acute and chronic inflammation in the hypothalamus: effect of high-fat diet, palmitate and TNF-α on appetite-regulating NPY neurons

(2016) P S Dalvi et al.   INTERNATIONAL JOURNAL OF OBESITY

Mammalian autophagy degrades nuclear constituents in response to tumorigenic stress

(2015) Zhixun Dou et al.   Autophagy

Effect of Ginseng (Panax ginseng) Berry EtOAc Fraction on Cognitive Impairment in C57BL/6 Mice under High-Fat Diet Inducement

(2015) Chang Hyeon Park et al.   Evidence-based Complementary and Alternative Medicine

Cellular senescence and the aging brain

(2015) Shankar J. Chinta et al.   EXPERIMENTAL GERONTOLOGY

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(2014) Chunhua Jin et al.   MOLECULAR MEDICINE

Insulin, cognition, and dementia

(2013) Brenna Cholerton et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Vitamin E prevents high-fat high-carbohydrates diet-induced memory impairment: The role of oxidative stress

(2013) Karem H. Alzoubi et al.   PHYSIOLOGY & BEHAVIOR

Heat Shock Proteins in the Brain: Role of Hsp70, Hsp 27, and HO-1 (Hsp32) and Their Therapeutic Potential

(2013) Frank R Sharp et al.   Translational Stroke Research

Tissue-type plasminogen activator protects neurons from excitotoxin-induced cell death via activation of the ERK1/2–CREB–ATF3 signaling pathway

(2012) Fang Wu et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Multi-faced neuroprotective effects of Ginsenoside Rg1 in an Alzheimer mouse model

(2011) Fang Fang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Inhibition of fatty acid oxidation by etomoxir impairs NADPH production and increases reactive oxygen species resulting in ATP depletion and cell death in human glioblastoma cells

(2010) Lisa S. Pike et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Senescent cells as a source of inflammatory factors for tumor progression

(2010) Albert R. Davalos et al.   CANCER AND METASTASIS REVIEWS

The enzymology of mitochondrial fatty acid beta-oxidation and its application to follow-up analysis of positive neonatal screening results

(2010) Ronald J. A. Wanders et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Role of Cytokines as Mediators and Regulators of Microglial Activity in Inflammatory Demyelination of the CNS

(2010) Tobias D. Merson et al.   NEUROMOLECULAR MEDICINE

Alteration of blood brain barrier permeability by T-2 toxin: Role of MMP-9 and inflammatory cytokines

(2010) Jayaraj Ravindran et al.   TOXICOLOGY

Ginsenoside Rg1 protects dopaminergic neurons in a rat model of Parkinson's disease through the IGF-I receptor signalling pathway

(2009) Li Xu et al.   BRITISH JOURNAL OF PHARMACOLOGY

Activation of innate immunity system during aging: NF-kB signaling is the molecular culprit of inflamm-aging

(2007) Antero Salminen et al.   AGEING RESEARCH REVIEWS