标题
Melatonin in Cancer Treatment: Current Knowledge and Future Opportunities
作者
关键词
-
出版物
MOLECULES
Volume 26, Issue 9, Pages 2506
出版商
MDPI AG
发表日期
2021-04-26
DOI
10.3390/molecules26092506
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Melatonin interrupts osteoclast functioning and suppresses tumor-secreted RANKL expression: implications for bone metastases
- (2021) Po-I Liu et al. ONCOGENE
- Melatonin- and Ferulic Acid-Based HDAC6 Selective Inhibitors Exhibit Pronounced Immunomodulatory Effects In Vitro and Neuroprotective Effects in a Pharmacological Alzheimer’s Disease Mouse Model
- (2021) Feng He et al. JOURNAL OF MEDICINAL CHEMISTRY
- Consumption of melatonin supplement improves cardiovascular disease risk factors and anthropometric indices in type 2 diabetes mellitus patients: a double-blind, randomized, placebo-controlled trial
- (2021) Hadi Bazyar et al. Trials
- Melatonin up‐regulates bone marrow mesenchymal stem cells osteogenic action but suppresses their mediated osteoclastogenesis via MT 2 ‐inactivated NF‐κB pathway
- (2020) Yi Zhou et al. BRITISH JOURNAL OF PHARMACOLOGY
- Effects of miR-34b/miR-892a Upregulation and Inhibition of ABCB1/ABCB4 on Melatonin-Induced Apoptosis in VCR-Resistant Oral Cancer Cells
- (2020) Ming-Ju Hsieh et al. Molecular Therapy-Nucleic Acids
- Melatonin’s Antineoplastic Potential Against Glioblastoma
- (2020) Enrico Moretti et al. Cells
- Melatonin prevents neuroinflammation and relieves depression by attenuating autophagy impairment through FOXO3a regulation
- (2020) Tahir Ali et al. JOURNAL OF PINEAL RESEARCH
- Melatonintriggered post‐transcriptional and post‐translational modifications of ADAMTS1 coordinately retard tumorigenesis and metastasis of renal cell carcinoma
- (2020) Yu‐Ching Wen et al. JOURNAL OF PINEAL RESEARCH
- Utilizing Melatonin to Alleviate Side Effects of Chemotherapy: A Potentially Good Partner for Treating Cancer with Ageing
- (2020) Zhiqiang Ma et al. Oxidative Medicine and Cellular Longevity
- Hydroxyl radical scavenging activity of melatonin and its related indolamines
- (2020) Aiswarya Purushothaman et al. FREE RADICAL RESEARCH
- Effects of melatonin to arecoline-induced reactive oxygen species production and DNA damage in oral squamous cell carcinoma
- (2020) Yin-Hwa Shih et al. JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION
- Cancer Incidence and Trends
- (2020) Melissa C. Hulvat SURGICAL CLINICS OF NORTH AMERICA
- Melatonin and urological cancers: a new therapeutic approach
- (2020) Mohammad Hossein Pourhanifeh et al. Cancer Cell International
- Melatonin regulates tumor angiogenesis via miR-424-5p/VEGFA signaling pathway in osteosarcoma
- (2020) Selvaraj Vimalraj et al. LIFE SCIENCES
- Resveratrol and Tumor Microenvironment: Mechanistic Basis and Therapeutic Targets
- (2020) Wamidh H. Talib et al. MOLECULES
- Melatonin Provides Protection Against Cisplatin-Induced Ovarian Damage and Loss of Fertility in Mice
- (2020) Wanying Shan et al. REPRODUCTIVE BIOMEDICINE ONLINE
- Melatonin suppresses chronic restraint stress-mediated metastasis of epithelial ovarian cancer via NE/AKT/β-catenin/SLUG axis
- (2020) Shixia Bu et al. Cell Death & Disease
- Melatonin increases overall survival of prostate cancer patients with poor prognosis after combined hormone radiation treatment
- (2020) Gennady M. Zharinov et al. Oncotarget
- Melatonin impedes prostate cancer metastasis by suppressing MMP‐13 expression
- (2020) Shih‐Wei Wang et al. JOURNAL OF CELLULAR PHYSIOLOGY
- The effects of melatonin daily supplementation to aged rats on the ability to withstand cold, thermoregulation and body weight
- (2020) Caroline Mendes et al. LIFE SCIENCES
- Potential use of melatonin in skin cancer treatment: A review of current biological evidence
- (2019) Mohammad Hossein Pourhanifeh et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Inhibition of TFEB oligomerization by co-treatment of melatonin with vorinostat promotes the therapeutic sensitivity in glioblastoma and glioma stem cells
- (2019) Gi-Jun Sung et al. JOURNAL OF PINEAL RESEARCH
- Melatonin and Docosahexaenoic Acid Decrease Proliferation of PNT1A Prostate Benign Cells via Modulation of Mitochondrial Bioenergetics and ROS Production
- (2019) Guilherme H. Tamarindo et al. Oxidative Medicine and Cellular Longevity
- Melatonin and its anti-glioma functions: a comprehensive review
- (2019) Sayantan Maitra et al. REVIEWS IN THE NEUROSCIENCES
- Overview of the oncogenic signaling pathways in colorectal cancer: Mechanistic insights
- (2019) Ammad Ahmad Farooqi et al. SEMINARS IN CANCER BIOLOGY
- Melatonin plays critical role in mesenchymal stem cell-based regenerative medicine in vitro and in vivo
- (2019) Chenxia Hu et al. Stem Cell Research & Therapy
- Effects of Extracellular Vesicles Derived from Mesenchymal Stem/stromal Cells on Liver Diseases
- (2019) Wenjie Zheng et al. Current Stem Cell Research & Therapy
- Melatonin is a potential inhibitor of ovarian cancer: molecular aspects
- (2019) Hadis Zare et al. Journal of Ovarian Research
- Transcriptional Regulation of Antioxidant Enzymes Activity and Modulation of Oxidative Stress by Melatonin in Rats Under Cerebral Ischemia / Reperfusion Conditions
- (2019) Evgenii D. Kryl'skii et al. NEUROSCIENCE
- Melatonin loaded with bacterial cellulose nanofiber by Pickering-emulsion solvent evaporation for enhanced dissolution and bioavailability
- (2019) Yuanyuan Li et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Exogenous Melatonin Up-Regulates Expression of CD62L by Lymphocytes in Aged Mice under Inflammatory and Non-Inflammatory Conditions
- (2019) Yuliya V. Perfilyeva et al. IMMUNOLOGICAL INVESTIGATIONS
- Melatonin suppresses lung cancer metastasis by inhibition of epithelial–mesenchymal transition through targeting to Twist
- (2019) Chia-Chia Chao et al. CLINICAL SCIENCE
- Downregulation of AKT and MDM2, Melatonin Induces Apoptosis in AGS and MGC803 Cells
- (2019) Jun Song et al. Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology
- Histone deacetylase 9 downregulation decreases tumor growth and promotes apoptosis in NSCLC after melatonin treatment
- (2019) Zhiqiang Ma et al. JOURNAL OF PINEAL RESEARCH
- The emergence of melatonin in oncology: Focus on colorectal cancer
- (2019) Emilio Gil‐Martín et al. MEDICINAL RESEARCH REVIEWS
- Immunoregulatory role of melatonin in cancer
- (2019) Fatemeh Moradkhani et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Melatonin reduces inflammatory response in human intestinal epithelial cells stimulated by interleukin‐1β
- (2019) Giuseppe Mannino et al. JOURNAL OF PINEAL RESEARCH
- Modulation of apoptosis by melatonin for improving cancer treatment efficiency: An updated review
- (2019) Keywan Mortezaee et al. LIFE SCIENCES
- Increased Nose-to-Brain Delivery of Melatonin Mediated by Polycaprolactone Nanoparticles for the Treatment of Glioblastoma
- (2019) Edilson Ribeiro de Oliveira Junior et al. PHARMACEUTICAL RESEARCH
- Melatonin Modulates the Microenvironment of Glioblastoma Multiforme by Targeting Sirtuin 1
- (2019) Sheng-Wei Lai et al. Nutrients
- Melatonin in Medicinal and Food Plants: Occurrence, Bioavailability, and Health Potential for Humans
- (2019) Bahare Salehi et al. Cells
- Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2017
- (2019) et al. JAMA Oncology
- Melatonin: an anti-tumor agent for osteosarcoma
- (2019) Hadis Fathizadeh et al. Cancer Cell International
- Melatonin restores the osteoporosis-impaired osteogenic potential of bone marrow mesenchymal stem cells by preserving SIRT1-mediated intracellular antioxidant properties
- (2019) Weikai Chen et al. FREE RADICAL BIOLOGY AND MEDICINE
- Melatonin activates cell death programs for the suppression of uterine leiomyoma cell proliferation
- (2019) Po‐Han Lin et al. JOURNAL OF PINEAL RESEARCH
- Ketogenic Diet Combined With Melatonin Overcomes Cisplatin and Vincrisitne Drug Resistance in Breast Carcinoma Syngraft
- (2019) Wamidh H. Talib NUTRITION
- The Therapeutic Effect of Melatonin on GC by Inducing Cell Apoptosis and Autophagy Induced by Endoplasmic Reticulum Stress
- (2019) Yanshan Zheng et al. OncoTargets and Therapy
- Inhibition of autophagy triggers melatonin-induced apoptosis in glioblastoma cells
- (2019) Nan Zhou et al. BMC NEUROSCIENCE
- The effects of melatonin on signaling pathways and molecules involved in glioma
- (2019) Foroogh Neamati et al. FUNDAMENTAL & CLINICAL PHARMACOLOGY
- Effect of melatonin on T/B cell activation and immune regulation in pinealectomy mice
- (2019) Jianhua Luo et al. LIFE SCIENCES
- Melatonin promotes the BMP9-induced osteogenic differentiation of mesenchymal stem cells by activating the AMPK/β-catenin signalling pathway
- (2019) Tianyuan Jiang et al. Stem Cell Research & Therapy
- Melatonin Reverses the Loss of Stemness Induced by TNF-α in Human Bone Marrow Mesenchymal Stem Cells through Upregulation of YAP Expression
- (2019) Xudong Wang et al. Stem Cells International
- The global, regional, and national burden of colorectal cancer and its attributable risk factors in 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017
- (2019) Saeid Safiri et al. Lancet Gastroenterology & Hepatology
- Melatonin Promotes Apoptosis of Colorectal Cancer CellsviaSuperoxide-mediated ER Stress by Inhibiting Cellular Prion Protein Expression
- (2018) CHUL WON YUN et al. ANTICANCER RESEARCH
- Oxidative stress and dietary phytochemicals: Role in cancer chemoprevention and treatment
- (2018) Shireen Chikara et al. CANCER LETTERS
- Enhanced cellular uptake and osteogenic differentiation efficiency of melatonin by inclusion complexation with 2-hydroxypropyl β-cyclodextrin
- (2018) Masahiko Terauchi et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Synergistic effect of thymoquinone and melatonin against breast cancer implanted in mice
- (2018) WamidhH Talib et al. Journal of Cancer Research and Therapeutics
- Quercetin: A functional dietary flavonoid with potential chemo-preventive properties in colorectal cancer
- (2018) Saber G. Darband et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Modified in vitro release of the chronobiotic hormone melatonin from matrix tablets based on the marine sulfated polysaccharide ulvan
- (2018) Marilena Vlachou et al. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
- EASL Clinical Practice Guidelines: Management of hepatocellular carcinoma
- (2018) Peter R. Galle et al. JOURNAL OF HEPATOLOGY
- Mitochondrial cytochrome P450 (CYP) 1B1 is responsible for melatonin-induced apoptosis in neural cancer cells
- (2018) Zhenlong Yu et al. JOURNAL OF PINEAL RESEARCH
- Melatonin restrains angiogenic factors in triple-negative breast cancer by targeting miR-152-3p: In vivo and in vitro studies
- (2018) Jéssica H.M. Marques et al. LIFE SCIENCES
- Melatonin and Cancer Hallmarks
- (2018) Wamidh Talib MOLECULES
- Mitochondria Transcription Factor A: A Putative Target for the Effect of Melatonin on U87MG Malignant Glioma Cell Line
- (2018) Daiane Franco et al. MOLECULES
- The Potential of Phytomelatonin as a Nutraceutical
- (2018) et al. MOLECULES
- Melatonin: A Versatile Protector against Oxidative DNA Damage
- (2018) Annia Galano et al. MOLECULES
- Melatonin induces the apoptosis and inhibits the proliferation of human gastric cancer cells via blockade of the AKT/MDM2 pathway
- (2018) Jun Song et al. ONCOLOGY REPORTS
- Melatonin Inhibits Reactive Oxygen Species-Driven Proliferation, Epithelial-Mesenchymal Transition, and Vasculogenic Mimicry in Oral Cancer
- (2018) Rui Liu et al. Oxidative Medicine and Cellular Longevity
- Melatonin suppresses eosinophils and Th17 cells in hamsters treated with a combination of human liver fluke infection and a chemical carcinogen
- (2018) Wachanan Wongsena et al. Pharmacological Reports
- Phytomelatonin, natural melatonin from plants as a novel dietary supplement: Sources, activities and world market
- (2018) Marino B. Arnao et al. Journal of Functional Foods
- Melatonin suppresses thyroid cancer growth and overcomes radioresistance via inhibition of p65 phosphorylation and induction of ROS
- (2018) Zhen-Wei Zou et al. Redox Biology
- Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
- (2018) Freddie Bray et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Preparation, characterization and in vitro evaluation of melatonin-loaded porous starch for enhanced bioavailability
- (2018) Yuanyuan Li et al. CARBOHYDRATE POLYMERS
- Melatonin as an adjuvant in radiotherapy for radioprotection and radiosensitization
- (2018) B. Farhood et al. Clinical & Translational Oncology
- AMPK/PGC1α activation by melatonin attenuates acute doxorubicin cardiotoxicity via alleviating mitochondrial oxidative damage and apoptosis
- (2018) Dong Liu et al. FREE RADICAL BIOLOGY AND MEDICINE
- Melatonin inhibits endoplasmic reticulum stress-associated TXNIP/NLRP3 inflammasome activation in lipopolysaccharide-induced endometritis in mice
- (2018) Xiaoyu Hu et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Melatonin reduces lung cancer stemness through inhibiting of PLC, ERK, p38, β-catenin, and Twist pathways
- (2018) Yi-Chen Yang et al. ENVIRONMENTAL TOXICOLOGY
- Melatonin Sensitizes Human Colorectal Cancer Cells to γ-ray Ionizing Radiation In Vitro and In Vivo
- (2018) Qin Wang et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Melatonin inhibits the migration of human gastric carcinoma cells at least in part by remodeling tight junction
- (2018) Xiang Wei et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Modified In Vitro Release of Melatonin Loaded in Nanofibrous Electrospun Mats Incorporated Into Monolayered and Three-Layered Tablets
- (2018) Marilena Vlachou et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- CADD-28. MELATONIN: TARGETING THE CELL’S POWERHOUSE TO FIGHT GLIOBLASTOMA
- (2018) Beatriz I Fernandez-Gil et al. NEURO-ONCOLOGY
- Melatonin: An Anti-Tumor Agent in Hormone-Dependent Cancers
- (2018) Javier Menéndez-Menéndez et al. International Journal of Endocrinology
- Promising Antineoplastic Actions of Melatonin
- (2018) Gaia Favero et al. Frontiers in Pharmacology
- Adverse events associated with oral administration of melatonin: A critical systematic review of clinical evidence
- (2018) Hope M. Foley et al. COMPLEMENTARY THERAPIES IN MEDICINE
- Melatonin-loaded silica coated with hydroxypropyl methylcellulose phthalate for enhanced oral bioavailability: Preparation, and in vitro-in vivo evaluation
- (2017) Yuanyuan Li et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Melatonin increases human cervical cancer HeLa cells apoptosis induced by cisplatin via inhibition of JNK/Parkin/mitophagy axis
- (2017) Li Chen et al. IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL
- Exosomes from Melatonin Treated Hepatocellularcarcinoma Cells Alter the Immunosupression Status through STAT3 Pathway in Macrophages
- (2017) Liang Cheng et al. International Journal of Biological Sciences
- Melatonin Inhibits Glioblastoma Stem-like cells through Suppression of EZH2-NOTCH1 Signaling Axis
- (2017) Xiangrong Zheng et al. International Journal of Biological Sciences
- Melatonin Inhibits Androgen Receptor Splice Variant-7 (AR-V7)-Induced Nuclear Factor-Kappa B (NF-κB) Activation and NF-κB Activator-Induced AR-V7 Expression in Prostate Cancer Cells: Potential Implications for the Use of Melatonin in Castration-Resistant Prostate Cancer (CRPC) Therapy
- (2017) Vincent Liu et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Melatonin, a Full Service Anti-Cancer Agent: Inhibition of Initiation, Progression and Metastasis
- (2017) Russel Reiter et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Melatonin Decreases Glucose Metabolism in Prostate Cancer Cells: A 13C Stable Isotope-Resolved Metabolomic Study
- (2017) David Hevia et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Melatonin inhibits colon cancer RKO cell migration by downregulating Rho-associated protein kinase expression via the p38/MAPK signaling pathway
- (2017) Zhen Liu et al. Molecular Medicine Reports
- Melatonin Pharmacokinetics Following Oral Administration in Preterm Neonates
- (2017) Silvia Carloni et al. MOLECULES
- CBTRUS Statistical Report: Primary brain and other central nervous system tumors diagnosed in the United States in 2010–2014
- (2017) Quinn T Ostrom et al. NEURO-ONCOLOGY
- Melatonin inhibits angiogenesis in SH-SY5Y human neuroblastoma cells by downregulation of VEGF
- (2017) Alicia González et al. ONCOLOGY REPORTS
- Melatonin, a novel selective ATF-6 inhibitor, induces human hepatoma cell apoptosis through COX-2 downregulation
- (2017) Li-Jia Bu et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Melatonin treatment induces apoptosis through regulating the nuclear factor-κB and mitogen-activated protein kinase signaling pathways in human gastric cancer SGC7901 cells
- (2017) Weimin Li et al. Oncology Letters
- What is known about melatonin, chemotherapy and altered gene expression in breast cancer
- (2017) Carlos Martínez-Campa et al. Oncology Letters
- Dietary Sources and Bioactivities of Melatonin
- (2017) Xiao Meng et al. Nutrients
- Melatonin exerts anti-oral cancer effect via suppressing LSD1 in patient-derived tumor xenograft models
- (2017) Cheng-Yu Yang et al. Oncotarget
- Melatonin for the prevention and treatment of cancer
- (2017) Ya Li et al. Oncotarget
- Exome Sequencing of Oral Squamous Cell Carcinoma Reveals Molecular Subgroups and Novel Therapeutic Opportunities
- (2017) Shih-Chi Su et al. Theranostics
- Non–Small Cell Lung Cancer, Version 2.2013
- (2017) David S. Ettinger et al. Journal of the National Comprehensive Cancer Network
- The potential therapeutic effect of melatonin on human ovarian cancer by inhibition of invasion and migration of cancer stem cells
- (2017) Maryam Akbarzadeh et al. Scientific Reports
- Glycine inhibits angiogenesis in colorectal cancer: role of endothelial cells
- (2016) Helge Bruns et al. AMINO ACIDS
- MT1and MT2Melatonin Receptors: A Therapeutic Perspective
- (2016) Jiabei Liu et al. Annual Review of Pharmacology and Toxicology
- Update on melatonin receptors: IUPHAR Review 20
- (2016) Ralf Jockers et al. BRITISH JOURNAL OF PHARMACOLOGY
- Cancer statistics, 2016
- (2016) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Pharmacokinetics of Melatonin: The Missing Link in Clinical Efficacy?
- (2016) Lars Peter Holst Andersen et al. CLINICAL PHARMACOKINETICS
- The Role of Melatonin in Palliative Care #306
- (2016) Georgina Waldman et al. JOURNAL OF PALLIATIVE MEDICINE
- IGFBP3 and MAPK/ERK signaling mediates melatonin-induced antitumor activity in prostate cancer
- (2016) Juan C. Mayo et al. JOURNAL OF PINEAL RESEARCH
- Melatonin inhibits MMP-9 transactivation and renal cell carcinoma metastasis by suppressing Akt-MAPKs pathway and NF-κB DNA-binding activity
- (2016) Yung-Wei Lin et al. JOURNAL OF PINEAL RESEARCH
- Melatonin inhibits tumorigenicity of glioblastoma stem-like cells via the AKT-EZH2-STAT3 signaling axis
- (2016) Xueran Chen et al. JOURNAL OF PINEAL RESEARCH
- Cancer metastasis: Mechanisms of inhibition by melatonin
- (2016) Shih-Chi Su et al. JOURNAL OF PINEAL RESEARCH
- Melatonin as an antioxidant: under promises but over delivers
- (2016) Russel J. Reiter et al. JOURNAL OF PINEAL RESEARCH
- Melatonin synergizes the chemotherapeutic effect of 5-fluorouracil in colon cancer by suppressing PI3K/AKT and NF-κB/iNOS signaling pathways
- (2016) Yue Gao et al. JOURNAL OF PINEAL RESEARCH
- Quantitative Proteomic Profiling Reveals That Diverse Metabolic Pathways Are Influenced by Melatonin in an in Vivo Model of Ovarian Carcinoma
- (2016) Luiz Gustavo A. Chuffa et al. JOURNAL OF PROTEOME RESEARCH
- Effects of combination of melatonin and laser irradiation on ovarian cancer cells and endothelial lineage viability
- (2016) Maryam Akbarzadeh et al. LASERS IN MEDICAL SCIENCE
- Epidemiological changes in the histological subtypes of 35,018 non-small-cell lung cancer cases in Brazil
- (2016) Guilherme Costa et al. LUNG CANCER
- Melatonin Represses Metastasis in Her2-Postive Human Breast Cancer Cells by Suppressing RSK2 Expression
- (2016) L. Mao et al. MOLECULAR CANCER RESEARCH
- Effect of Melatonin in Epithelial Mesenchymal Transition Markers and Invasive Properties of Breast Cancer Stem Cells of Canine and Human Cell Lines
- (2016) Naiane do Nascimento Gonçalves et al. PLoS One
- The Warburg Effect: How Does it Benefit Cancer Cells?
- (2016) Maria V. Liberti et al. TRENDS IN BIOCHEMICAL SCIENCES
- Effects of melatonin on HIF-1α and VEGF expression and on the invasive properties of hepatocarcinoma cells
- (2016) JUCIMARA COLOMBO et al. Oncology Letters
- Melatonin downregulates nuclear receptor RZR/RORγ expression causing growth-inhibitory and anti-angiogenesis activity in human gastric cancer cells in vitro and in vivo
- (2016) Ri-Xiong Wang et al. Oncology Letters
- Dietary Natural Products for Prevention and Treatment of Liver Cancer
- (2016) Yue Zhou et al. Nutrients
- Melatonin inhibits TPA-induced oral cancer cell migration by suppressing matrix metalloproteinase-9 activation through the histone acetylation
- (2016) Chia-Ming Yeh et al. Oncotarget
- Melatonin as a potential anticarcinogen for non-small-cell lung cancer
- (2016) Zhiqiang Ma et al. Oncotarget
- Urinary melatonin-sulfate/cortisol ratio and the presence of prostate cancer: A case-control study
- (2016) Shu-Yu Tai et al. Scientific Reports
- Optimization of Melatonin Dissolution from Extended Release Matrices Using Artificial Neural Networking
- (2016) Martarelli D. et al. Current Drug Delivery
- Exogenous Melatonin Improves Antioxidant Defense in Cucumber Seeds (Cucumis sativus L.) Germinated under Chilling Stress
- (2016) Bałabusta Marta et al. Frontiers in Plant Science
- Glioma Stem Cells: Signaling, Microenvironment, and Therapy
- (2016) Brandon D. Liebelt et al. Stem Cells International
- Pharmacokinetics of oral and intravenous melatonin in healthy volunteers
- (2016) Lars P. H. Andersen et al. BMC Pharmacology & Toxicology
- Dissolution of Intact, Divided and Crushed Circadin Tablets: Prolonged vs. Immediate Release of Melatonin
- (2016) Hui Chua et al. Pharmaceutics
- The levels of melatonin and its metabolites in conditioned corn (Zea mays L.) and cucumber (Cucumis sativus L.) seeds during storage
- (2015) Izabela Kołodziejczyk et al. ACTA PHYSIOLOGIAE PLANTARUM
- Melatonin attenuates the TLR4-mediated inflammatory response through MyD88- and TRIF-dependent signaling pathways in an in vivo model of ovarian cancer
- (2015) Luiz Gustavo A Chuffa et al. BMC CANCER
- Global cancer statistics, 2012
- (2015) Lindsey A. Torre et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Effects of melatonin on physical fatigue and other symptoms in patients with advanced cancer receiving palliative care: A double-blind placebo-controlled crossover trial
- (2015) Charlotte Lund Rasmussen et al. CANCER
- Melatonin potentiates cisplatin-induced apoptosis and cell cycle arrest in human lung adenocarcinoma cells
- (2015) P. Plaimee et al. CELL PROLIFERATION
- Antioxidant Properties of Melatonin and its Potential Action in Diseases
- (2015) Cigdem Karaaslan et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Melatonin: an inhibitor of breast cancer
- (2015) S. M. Hill et al. ENDOCRINE-RELATED CANCER
- Clinical pharmacokinetics of melatonin: a systematic review
- (2015) Nathja Groth Harpsøe et al. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
- Urinary Melatonin Levels, Sleep Disruption, and Risk of Prostate Cancer in Elderly Men
- (2015) Lara G. Sigurdardottir et al. EUROPEAN UROLOGY
- Melatonin sensitizes human breast cancer cells to ionizing radiation by downregulating proteins involved in double-strand DNA break repair
- (2015) Carolina Alonso-González et al. JOURNAL OF PINEAL RESEARCH
- Melatonin-mediated Bim up-regulation and cyclooxygenase-2 (COX-2) down-regulation enhances tunicamycin-induced apoptosis in MDA-MB-231 cells
- (2015) Seon Min Woo et al. JOURNAL OF PINEAL RESEARCH
- Melatonin induces apoptosis of colorectal cancer cells through HDAC4 nuclear import mediated by CaMKII inactivation
- (2015) Jia-Yi Wei et al. JOURNAL OF PINEAL RESEARCH
- Ceramide metabolism regulates autophagy and apoptotic cell death induced by melatonin in liver cancer cells
- (2015) Raquel Ordoñez et al. JOURNAL OF PINEAL RESEARCH
- Melatonin: Physiological effects in humans
- (2015) B. Claustrat et al. NEUROCHIRURGIE
- Involvement of nuclear receptor RZR/RORγ in melatonin-induced HIF-1α inactivation in SGC-7901 human gastric cancer cells
- (2015) RI-XIONG WANG et al. ONCOLOGY REPORTS
- The effect of melatonin on sleep and quality of life in patients with advanced breast cancer
- (2015) Pasquale F. Innominato et al. SUPPORTIVE CARE IN CANCER
- Integrating Systemic and Surgical Approaches to Treating Metastatic Colorectal Cancer
- (2015) Kaihong Mi et al. Surgical Oncology Clinics of North America
- Hepatocellular Carcinoma in Liver Cirrhosis: Surgical Resection versus Transarterial Chemoembolization—A Meta-Analysis
- (2015) Teodor Kapitanov et al. Gastroenterology Research and Practice
- Melatonin inhibits AP-2β/hTERT, NF-κB/COX-2 and Akt/ERK and activates caspase/Cyto C signaling to enhance the antitumor activity of berberine in lung cancer cells
- (2015) Jian-Jun Lu et al. Oncotarget
- Signal Transduction in Cancer
- (2015) R. Sever et al. Cold Spring Harbor Perspectives in Medicine
- Upregulation of miRNA3195 and miRNA374b Mediates the Anti-Angiogenic Properties of Melatonin in Hypoxic PC-3 Prostate Cancer Cells
- (2015) Eun Jung Sohn et al. Journal of Cancer
- Pharmacologic resistance in colorectal cancer: a review
- (2015) William A. Hammond et al. Therapeutic Advances in Medical Oncology
- Propionibacterium acnes Augments Antitumor, Anti-Angiogenesis and Immunomodulatory Effects of Melatonin on Breast Cancer Implanted in Mice
- (2015) Wamidh H. Talib et al. PLoS One
- Melatonin Cytotoxicity Is Associated to Warburg Effect Inhibition in Ewing Sarcoma Cells
- (2015) Ana M. Sanchez-Sanchez et al. PLoS One
- A systematic review of peri-operative melatonin
- (2014) L. P. H. Andersen et al. ANAESTHESIA
- Molecular Markers of Angiogenesis and Metastasis in Lines of Oral Carcinoma after Treatment with Melatonin
- (2014) Naiane Goncalves et al. Anti-Cancer Agents in Medicinal Chemistry
- Oxidative Stress and Antioxidants in Disease and Cancer: A Review
- (2014) Rakesh Kumar Gupta et al. Asian Pacific Journal of Cancer Prevention
- Effect of melatonin on depressive symptoms and anxiety in patients undergoing breast cancer surgery: a randomized, double-blind, placebo-controlled trial
- (2014) Melissa V. Hansen et al. BREAST CANCER RESEARCH AND TREATMENT
- A randomized, placebo-controlled trial of melatonin on breast cancer survivors: impact on sleep, mood, and hot flashes
- (2014) Wendy Y. Chen et al. BREAST CANCER RESEARCH AND TREATMENT
- Urinary Excretion of Melatonin and Association with Breast Cancer: Meta-Analysis and Review of the Literature
- (2014) Michelle Basler et al. Breast Care
- Long-term and Short-term Effects of Insomnia in Cancer and Effective Interventions
- (2014) Mellar P. Davis et al. CANCER JOURNAL
- Immunomodulatory effect of melatonin in SK-LU-1 human lung adenocarcinoma cells co-cultured with peripheral blood mononuclear cells
- (2014) P. Plaimee et al. CELL PROLIFERATION
- Melatonin Sensitizes H1975 Non-Small-Cell Lung Cancer Cells Harboring a T790M-Targeted Epidermal Growth Factor Receptor Mutation to the Tyrosine Kinase Inhibitor Gefitinib
- (2014) Miyong Yun et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Soft gel capsules improve melatonin’s bioavailability in humans
- (2014) Sara Proietti et al. Expert Opinion on Drug Metabolism & Toxicology
- Recent Clinical Advances in Lung Cancer Management
- (2014) David H. Johnson et al. JOURNAL OF CLINICAL ONCOLOGY
- Melatonin treatment induces interplay of apoptosis, autophagy, and senescence in human colorectal cancer cells
- (2014) Yunkyung Hong et al. JOURNAL OF PINEAL RESEARCH
- Additional benefit of combined therapy with melatonin and apoptotic adipose-derived mesenchymal stem cell against sepsis-induced kidney injury
- (2014) Hong-Hwa Chen et al. JOURNAL OF PINEAL RESEARCH
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- (2013) S Zhang et al. BIOTECHNIC & HISTOCHEMISTRY
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- (2013) S Carbajo-Pescador et al. BRITISH JOURNAL OF CANCER
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- (2012) Radomir M. Slominski et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
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- (2012) Jian Chen et al. NATURE
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- (2011) Melanie Stürtz et al. FOOD CHEMISTRY
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- (2011) Peilin Cui et al. JOURNAL OF PINEAL RESEARCH
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- (2011) Sung-Yun Cho et al. JOURNAL OF PINEAL RESEARCH
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- (2011) Ping Wang et al. JOURNAL OF PINEAL RESEARCH
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- (2011) Z. Shen Journal of Molecular Cell Biology
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- (2011) David González-Flores et al. Food & Function
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- (2010) Premila Abraham et al. CELL BIOCHEMISTRY AND FUNCTION
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- (2010) Francesca Luchetti et al. FASEB JOURNAL
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- (2010) Jacques Ferlay et al. INTERNATIONAL JOURNAL OF CANCER
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- (2010) Peter B. Dirks Molecular Oncology
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- (2010) Lu-Lu Fan WORLD JOURNAL OF GASTROENTEROLOGY
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- (2009) Candace A. Gilbert et al. JOURNAL OF CELLULAR BIOCHEMISTRY
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- (2008) Johanna Hilli et al. JOURNAL OF CLINICAL PHARMACOLOGY
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- (2008) Sheng-Hai Huang et al. JOURNAL OF PINEAL RESEARCH
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- (2008) Ahmet Korkmaz et al. JOURNAL OF PINEAL RESEARCH
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- (2008) Andrzej Slominski et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
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- (2008) Sanjay R Hegde et al. Expert Review of Gastroenterology & Hepatology
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