Xanthoceraside modulates NR2B-containing NMDA receptors at synapses and rescues learning-memory deficits in APP/PS1 transgenic mice

Xanthoceraside modulates neurogenesis to ameliorate cognitive impairment in APP/PS1 transgenic mice

(2017) Lin Zhu et al.   Journal of Physiological Sciences

T-type calcium channels contribute to NMDA receptor independent synaptic plasticity in hippocampal regular-spiking oriens-alveus interneurons

(2017) Elizabeth Nicholson et al.   JOURNAL OF PHYSIOLOGY-LONDON

Dysfunction of NMDA receptors in Alzheimer’s disease

(2016) Yan Zhang et al.   NEUROLOGICAL SCIENCES

Xanthoceras sorbifolia extracts ameliorate dendritic spine deficiency and cognitive decline via upregulation of BDNF expression in a rat model of Alzheimer's disease

(2016) Yinjie Li et al.   NEUROSCIENCE LETTERS

Perilla frutescensvar.japonicaand rosmarinic acid improve amyloid-β25-35induced impairment of cognition and memory function

(2016) Ah Young Lee et al.   Nutrition Research and Practice

Replenishment of microRNA-188-5p restores the synaptic and cognitive deficits in 5XFAD Mouse Model of Alzheimer’s Disease

(2016) Kihwan Lee et al.   Scientific Reports

ASPP2 involvement in p53-mediated HIV-1 envelope glycoprotein gp120 neurotoxicity in mice cerebrocortical neurons

(2016) Zhiying Liu et al.   Scientific Reports

MiR-299-5p regulates apoptosis through autophagy in neurons and ameliorates cognitive capacity in APPswe/PS1dE9 mice

(2016) Yueqi Zhang et al.   Scientific Reports

Amyloid precursor protein expression and processing are differentially regulated during cortical neuron differentiation

(2016) Petra Bergström et al.   Scientific Reports

Protease activated receptor 1 (PAR1) enhances Src-mediated tyrosine phosphorylation of NMDA receptor in intracerebral hemorrhage (ICH)

(2016) Zhen-Zhen Duan et al.   Scientific Reports

STEP activation by Gαq coupled GPCRs opposes Src regulation of NMDA receptors containing the GluN2A subunit

(2016) Meng Tian et al.   Scientific Reports

Striatal-enriched protein tyrosine phosphatase regulates the PTPα/Fyn signaling pathway

(2015) Jian Xu et al.   JOURNAL OF NEUROCHEMISTRY

A novel phosphodiesterase-5 Inhibitor: Yonkenafil modulates neurogenesis, gliosis to improve cognitive function and ameliorates amyloid burden in an APP/PS1 transgenic mice model

(2015) Lei Zhu et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Conjugates of γ-Carbolines and Phenothiazine as new selective inhibitors of butyrylcholinesterase and blockers of NMDA receptors for Alzheimer Disease

(2015) Galina F. Makhaeva et al.   Scientific Reports

Potassium 2-(1-hydroxypentyl)-benzoate promotes long-term potentiation in Aβ1–42-injected rats and APP/PS1 transgenic mice

(2014) Ping-ping Li et al.   ACTA PHARMACOLOGICA SINICA

Xanthoceraside rescues learning and memory deficits through attenuating beta-amyloid deposition and tau hyperphosphorylation in APP mice

(2014) Ge Jin et al.   NEUROSCIENCE LETTERS

Disruption of striatal-enriched protein tyrosine phosphatase (STEP) function in neuropsychiatric disorders

(2014) Takatoshi Karasawa et al.   NEUROSCIENCE RESEARCH

Methyllycaconitine Alleviates Amyloid-β Peptides-Induced Cytotoxicity in SH-SY5Y Cells

(2014) XiaoLei Zheng et al.   PLoS One

Protective effect of xanthoceraside against β-amyloid-induced neurotoxicity in neuroblastoma SH-SY5Y cells

(2013) Tian-Yan Chi et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

L-type Ca2+ currents at CA1 synapses, but not CA3 or dentate granule neuron synapses, are increased in 3xTgAD mice in an age-dependent manner

(2013) Yue Wang et al.   NEUROBIOLOGY OF AGING

A  induces astrocytic glutamate release, extrasynaptic NMDA receptor activation, and synaptic loss

(2013) M. Talantova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuroprotective effect of estrogen: Role of nonsynaptic NR2B-containing NMDA receptors

(2012) Shui-bing Liu et al.   BRAIN RESEARCH BULLETIN

The E3 ligase APC/C-Cdh1 is required for associative fear memory and long-term potentiation in the amygdala of adult mice

(2012) J. E. Pick et al.   LEARNING & MEMORY

NMDA receptors and BAX are essential for Aβ impairment of LTP

(2012) Kimberly Moore Olsen et al.   Scientific Reports

Mechanisms underlying NMDA receptor synaptic/extrasynaptic distribution and function

(2011) Clare M. Gladding et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Aβ1–42 inhibition of LTP is mediated by a signaling pathway involving caspase-3, Akt1 and GSK-3β

(2011) Jihoon Jo et al.   NATURE NEUROSCIENCE

Alcohol inhibition of the NMDA receptor function, long-term potentiation, and fear learning requires striatal-enriched protein tyrosine phosphatase

(2011) T. R. Hicklin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Xanthoceraside attenuates amyloid β peptide25–35-induced learning and memory impairments in mice

(2011) Ping Lu et al.   PSYCHOPHARMACOLOGY

A -Mediated NMDA Receptor Endocytosis in Alzheimer's Disease Involves Ubiquitination of the Tyrosine Phosphatase STEP61

(2010) P. Kurup et al.   JOURNAL OF NEUROSCIENCE

Genetic reduction of striatal-enriched tyrosine phosphatase (STEP) reverses cognitive and cellular deficits in an Alzheimer's disease mouse model

(2010) Y. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synaptic degeneration in Alzheimer’s disease

(2009) Thomas Arendt   ACTA NEUROPATHOLOGICA

Age-related cognitive decline and nesting behavior in an APPswe/PS1 bigenic model of Alzheimer's disease

(2009) Mohammed Filali et al.   BRAIN RESEARCH

β-Amyloid Impairs AMPA Receptor Trafficking and Function by Reducing Ca2+/Calmodulin-dependent Protein Kinase II Synaptic Distribution

(2009) Zhenglin Gu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Amyloid beta from axons and dendrites reduces local spine number and plasticity

(2009) Wei Wei et al.   NATURE NEUROSCIENCE

Inducible and Selective Erasure of Memories in the Mouse Brain via Chemical-Genetic Manipulation

(2008) Xiaohua Cao et al.   NEURON

Surface trafficking of N-methyl-d-aspartate receptors: Physiological and pathological perspectives

(2008) L. Groc et al.   NEUROSCIENCE

Phospho-regulation of synaptic and extrasynaptic N-methyl-d-aspartate receptors in adult hippocampal slices

(2008) S.M. Goebel-Goody et al.   NEUROSCIENCE