标题
The Current and Potential Therapeutic Use of Metformin—The Good Old Drug
作者
关键词
-
出版物
Pharmaceuticals
Volume 14, Issue 2, Pages 122
出版商
MDPI AG
发表日期
2021-02-05
DOI
10.3390/ph14020122
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- The Long-term Effects of Metformin on Patients With Type 2 Diabetic Kidney Disease
- (2020) Soie Kwon et al. DIABETES CARE
- Comorbidity and its impact on 1590 patients with COVID-19 in China: a nationwide analysis
- (2020) Wei-jie Guan et al. EUROPEAN RESPIRATORY JOURNAL
- Anti-Inflammatory Strategies Targeting Metaflammation in Type 2 Diabetes
- (2020) Alina Kuryłowicz et al. MOLECULES
- Diabetes and COVID-19
- (2020) Slobodan Peric et al. WIENER KLINISCHE WOCHENSCHRIFT
- Metformin treatment in heart failure with preserved ejection fraction: a systematic review and meta-regression analysis
- (2020) Amera Halabi et al. Cardiovascular Diabetology
- A New Drug–Drug Interaction Between Hydroxychloroquine and Metformin? A Signal Detection Study
- (2020) Jean-Louis Montastruc et al. DRUG SAFETY
- Significance of Metformin Use in Diabetic Kidney Disease
- (2020) Daiji Kawanami et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Practical recommendations for the management of diabetes in patients with COVID-19
- (2020) Stefan R Bornstein et al. Lancet Diabetes & Endocrinology
- Risk of Anemia With Metformin Use in Type 2 Diabetes: A MASTERMIND Study
- (2020) Louise A. Donnelly et al. DIABETES CARE
- Pharmacogenetics of Type 2 Diabetes—Progress and Prospects
- (2020) Yulia A. Nasykhova et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Association of Glycemic Indices (Hyperglycemia, Glucose Variability, and Hypoglycemia) with Oxidative Stress and Diabetic Complications
- (2020) Eleftheria Papachristoforou et al. Journal of Diabetes Research
- Cardiovascular effects of SGLT-2 inhibitors: What we have learned from cardiovascular outcome trials and what we still need to understand
- (2019) Ilaria Cavallari et al. DIABETES-METABOLISM RESEARCH AND REVIEWS
- Neuro-Protective Role of Metformin in Patients with Acute Stroke and Type 2 Diabetes Mellitus via AMPK/Mammalian Target of Rapamycin (mTOR) Signaling Pathway and Oxidative Stress
- (2019) Min Zhao et al. MEDICAL SCIENCE MONITOR
- Metformin and gut microbiota: their interactions and their impact on diabetes
- (2019) Natalia G. Vallianou et al. Hormones-International Journal of Endocrinology and Metabolism
- Duration of Diabetes and Cardiorenal Efficacy of Liraglutide and Semaglutide: A Post Hoc Analysis of the LEADER and SUSTAIN 6 Clinical Trials
- (2019) Subodh Verma et al. DIABETES OBESITY & METABOLISM
- Metformin use and cardiovascular events in patients with type 2 diabetes and chronic kidney disease
- (2019) David M. Charytan et al. DIABETES OBESITY & METABOLISM
- Effects of metformin therapy on COronary endothelial DYsfunction in prediabetic patients With stable angina and Non Obstructive Coronary Artery Stenosis: The CODYCE Multicenter Prospective Study
- (2019) Celestino Sardu et al. DIABETES CARE
- Effects of empagliflozin on metabolic parameters in polycystic ovary syndrome: a randomised controlled study
- (2019) Zeeshan Javed et al. CLINICAL ENDOCRINOLOGY
- Effect of Dapagliflozin on Heart Failure and Mortality in Type 2 Diabetes Mellitus
- (2019) Eri T. Kato et al. CIRCULATION
- Mechanisms of action of metformin with special reference to cardiovascular protection
- (2019) Alexey V. Zilov et al. DIABETES-METABOLISM RESEARCH AND REVIEWS
- A randomized controlled trial of metformin on left ventricular hypertrophy in patients with coronary artery disease without diabetes: the MET-REMODEL trial
- (2019) Mohapradeep Mohan et al. EUROPEAN HEART JOURNAL
- Metformin Improves Peripheral Insulin Sensitivity in Youth with Type 1 Diabetes
- (2019) Melanie Cree-Green et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy
- (2019) Vlado Perkovic et al. NEW ENGLAND JOURNAL OF MEDICINE
- GLP-1 receptor agonists versus metformin in polycystic ovary syndrome: a systematic review and meta-analysis
- (2019) Yi Han et al. REPRODUCTIVE BIOMEDICINE ONLINE
- Metformin Treatment and Cancer Risk: Cox Regression Analysis with Time-Dependent Covariates of 320,000 Individuals with Incident Diabetes Mellitus
- (2019) Rachel Dankner et al. AMERICAN JOURNAL OF EPIDEMIOLOGY
- Effect of metformin on all-cause and cardiovascular mortality in patients with coronary artery diseases: a systematic review and an updated meta-analysis
- (2019) Yechen Han et al. Cardiovascular Diabetology
- Association of Metformin Use With End‐Stage Renal Disease in Patients With Type 2 Diabetes Mellitus: A Nationwide Cohort Study Under the Pay‐for‐Performance Program
- (2019) Ming‐Chia Lee et al. JOURNAL OF CLINICAL PHARMACOLOGY
- Basic Research in Diabetic Nephropathy Health Care: A study of the Renoprotective Mechanism of Metformin
- (2019) Jing Xue et al. JOURNAL OF MEDICAL SYSTEMS
- SGLT2 Inhibitors: Nephroprotective Efficacy and Side Effects
- (2019) Carlo Garofalo et al. Medicina-Lithuania
- Review of Glucagon‐Like Peptide‐1 Receptor Agonists for the Treatment of Type 2 Diabetes Mellitus in Patients With Chronic Kidney Disease and Their Renal Effects
- (2019) Lance A. Sloan Journal of Diabetes
- Effects of metformin and phenformin on apoptosis and epithelial‐mesenchymal transition in chemoresistant rectal cancer
- (2019) Ji‐Hye Park et al. CANCER SCIENCE
- Cardiovascular outcomes in trials of new antidiabetic drug classes: a network meta-analysis
- (2019) Yue Fei et al. Cardiovascular Diabetology
- Pericoronary fat inflammation and Major Adverse Cardiac Events (MACE) in prediabetic patients with acute myocardial infarction: effects of metformin
- (2019) Celestino Sardu et al. Cardiovascular Diabetology
- The role of an anti-diabetic drug metformin in the treatment of endocrine tumors
- (2019) Shilpa Thakur et al. JOURNAL OF MOLECULAR ENDOCRINOLOGY
- Association between metformin dose and vitamin B12 deficiency in patients with type 2 diabetes
- (2019) Jiwoon Kim et al. MEDICINE
- Metformin in pregnancy to avert gestational diabetes in women at high risk: Meta‐analysis of randomized controlled trials
- (2019) Suhail A.R. Doi et al. Obesity Reviews
- Monotherapy with Metformin versus Sulfonylureas and Risk of Cancer in Type 2 Diabetic Patients: A Systematic Review and Meta-Analysis
- (2019) Abraham Nigussie Mekuria et al. Journal of Diabetes Research
- Antidiabetic medication use during pregnancy: an international utilization study
- (2019) Carolyn E Cesta et al. BMJ Open Diabetes Research & Care
- 2019 Update to: Management of Hyperglycemia in Type 2 Diabetes, 2018. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)
- (2019) John B. Buse et al. DIABETES CARE
- 3. Prevention or Delay of Type 2 Diabetes: Standards of Medical Care in Diabetes—2020
- (2019) DIABETES CARE
- 9. Pharmacologic Approaches to Glycemic Treatment: Standards of Medical Care in Diabetes—2020
- (2019) DIABETES CARE
- Effects of metformin administration on endocrine-metabolic parameters, visceral adiposity and cardiovascular risk factors in children with obesity and risk markers for metabolic syndrome: A pilot study
- (2019) Judit Bassols et al. PLoS One
- Renal Outcomes in Type 2 Diabetes: A Review of Cardiovascular and Renal Outcome Trials
- (2019) David M. Williams et al. Diabetes Therapy
- Ovulation induction in polycystic ovary syndrome
- (2018) Tom Tanbo et al. ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA
- Metformin regulates metabolic and nonmetabolic pathways in skeletal muscle and subcutaneous adipose tissues of older adults
- (2018) Ameya S Kulkarni et al. AGING CELL
- GLP-1 Receptor Agonists and Cardiovascular Disease: a Meta-Analysis of Recent Cardiac Outcome Trials
- (2018) Xiaoming Jia et al. CARDIOVASCULAR DRUGS AND THERAPY
- Cardiovascular Effects of New Oral Glucose-Lowering Agents
- (2018) André J. Scheen CIRCULATION RESEARCH
- Metformin
- (2018) Julie Rodriguez et al. CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE
- Metformin in cancer
- (2018) Ritwika Mallik et al. DIABETES RESEARCH AND CLINICAL PRACTICE
- DPP4 INHIBITOR SITAGLIPTIN AS A POTENTIAL TREATMENT OPTION IN METFORMIN-INTOLERANT OBESE WOMEN WITH POLYCYSTIC OVARY SYNDROME: A PILOT RANDOMIZED STUDY
- (2018) Simona Ferjan et al. Endocrine Practice
- The Effect of Metformin Therapy for Preventing Gestational Diabetes Mellitus in Women with Polycystic Ovary Syndrome: A Meta-Analysis
- (2018) Jing Zhao et al. EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES
- Metformin ameliorates the progression of atherosclerosis via suppressing macrophage infiltration and inflammatory responses in rabbits
- (2018) Qiangbing Yang et al. LIFE SCIENCES
- Metformin attenuates triglyceride accumulation in HepG2 cells through decreasing stearyl-coenzyme A desaturase 1 expression
- (2018) Xiaopeng Zhu et al. Lipids in Health and Disease
- Genetic polymorphisms of organic cation transporter 1 (OCT1) and responses to metformin therapy in individuals with type 2 diabetes
- (2018) Edith Pascale Mofo Mato et al. MEDICINE
- Mechanisms of metformin action: In and out of the gut
- (2018) Takahiro Minamii et al. Journal of Diabetes Investigation
- Review of Metformin Use for Type 2 Diabetes Prevention
- (2018) Tannaz Moin et al. AMERICAN JOURNAL OF PREVENTIVE MEDICINE
- Metformin as geroprotector: experimental and clinical evidence
- (2018) Veronika Piskovatska et al. BIOGERONTOLOGY
- Metabolic Effects of Metformin in the Failing Heart
- (2018) Aleksandra Dziubak et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Metformin: An Old Drug with New Applications
- (2018) Joseph Zhou et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Analysis of the Global Burden of Disease study highlights the global, regional, and national trends of chronic kidney disease epidemiology from 1990 to 2016
- (2018) Yan Xie et al. KIDNEY INTERNATIONAL
- Endothelial function and dysfunction: Impact of metformin
- (2018) Asma Nafisa et al. PHARMACOLOGY & THERAPEUTICS
- Metformin as an Anticancer Agent
- (2018) Ales Vancura et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Management of Hyperglycemia in Type 2 Diabetes, 2018. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)
- (2018) Melanie J. Davies et al. DIABETES CARE
- SGLT Inhibitors for Type 1 Diabetes: An Obvious Choice or Too Good to Be True?
- (2018) Matthew C. Riddle et al. DIABETES CARE
- Efficacy and Safety of Dapagliflozin in Patients With Inadequately Controlled Type 1 Diabetes: The DEPICT-1 52-Week Study
- (2018) Paresh Dandona et al. DIABETES CARE
- Empagliflozin as Adjunctive to Insulin Therapy in Type 1 Diabetes: The EASE Trials
- (2018) Julio Rosenstock et al. DIABETES CARE
- Dipeptidyl peptidase-4 and adenosine deaminase enzyme levels in polycystic ovary syndrome
- (2018) Bahadır Öztürk et al. GYNECOLOGICAL ENDOCRINOLOGY
- Effect of Linagliptin vs Placebo on Major Cardiovascular Events in Adults With Type 2 Diabetes and High Cardiovascular and Renal Risk
- (2018) Julio Rosenstock et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Metformin induces significant reduction of body weight, total cholesterol and LDL levels in the elderly – A meta-analysis
- (2018) Margit Solymár et al. PLoS One
- Sodium glucose cotransporter 2 inhibitors and risk of serious adverse events: nationwide register based cohort study
- (2018) Peter Ueda et al. BMJ-British Medical Journal
- Effects of metformin treatment on radiotherapy efficacy in patients with cancer and diabetes: a systematic review and meta-analysis
- (2018) Mingyue Rao et al. Cancer Management and Research
- Metformin-Induced Mitochondrial Complex I Inhibition: Facts, Uncertainties, and Consequences
- (2018) Eric Fontaine Frontiers in Endocrinology
- Inhibition of mitochondrial complex I improves glucose metabolism independently of AMPK activation
- (2017) Wo-Lin Hou et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Metformin prevents glucotoxicity by alleviating oxidative and ER stress–induced CD36 expression in pancreatic beta cells
- (2017) Jun Sung Moon et al. JOURNAL OF DIABETES AND ITS COMPLICATIONS
- Dipeptidyl Peptidase-4 Inhibitor Sitagliptin Prevented Weight Regain in Obese Women with Polycystic Ovary Syndrome Previously Treated with Liraglutide: A Pilot Randomized Study
- (2017) Simona Ferjan et al. Metabolic Syndrome and Related Disorders
- Regulation of hepatic glucose metabolism in health and disease
- (2017) Max C. Petersen et al. Nature Reviews Endocrinology
- Effects of Sotagliflozin Added to Insulin in Patients with Type 1 Diabetes
- (2017) Satish K. Garg et al. NEW ENGLAND JOURNAL OF MEDICINE
- Metformin effects on the heart and the cardiovascular system: A review of experimental and clinical data
- (2017) L. Nesti et al. NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
- Metformin; a review of its history and future: from lilac to longevity
- (2017) Inas Thomas et al. PEDIATRIC DIABETES
- Metformin – its potential anti-cancer and anti-aging effects
- (2017) Monika Podhorecka et al. Postepy Higieny I Medycyny Doswiadczalnej
- Metformin attenuates ER stress–induced mitochondrial dysfunction
- (2017) Qun Chen et al. Translational Research
- Risk of acute kidney injury and survival in patients treated with Metformin: an observational cohort study
- (2017) Samira Bell et al. BMC Nephrology
- Cardiovascular and metabolic effects of metformin in patients with type 1 diabetes (REMOVAL): a double-blind, randomised, placebo-controlled trial
- (2017) John R Petrie et al. Lancet Diabetes & Endocrinology
- Efficacy and safety of dapagliflozin in patients with inadequately controlled type 1 diabetes (DEPICT-1): 24 week results from a multicentre, double-blind, phase 3, randomised controlled trial
- (2017) Paresh Dandona et al. Lancet Diabetes & Endocrinology
- Metformin inhibits gastric cancer cells metastatic traits through suppression of epithelial-mesenchymal transition in a glucose-independent manner
- (2017) Shiva Valaee et al. PLoS One
- A systematic review and meta-analysis of the protective effects of metformin in experimental myocardial infarction
- (2017) Nienke A. Hesen et al. PLoS One
- Effects of metformin on inflammation, oxidative stress, and bone loss in a rat model of periodontitis
- (2017) Aurigena Antunes de Araújo et al. PLoS One
- Metformin Improves Endothelial Function and Reduces Blood Pressure in Diabetic Spontaneously Hypertensive Rats Independent from Glycemia Control: Comparison to Vildagliptin
- (2017) Mahdi Hamidi Shishavan et al. Scientific Reports
- Treatment of nonalcoholic fatty liver disease: role of AMPK
- (2016) Brennan K. Smith et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Metformin as an adjuvant treatment for cancer: a systematic review and meta-analysis
- (2016) C. Coyle et al. ANNALS OF ONCOLOGY
- Metformin and the gastrointestinal tract
- (2016) Laura J. McCreight et al. DIABETOLOGIA
- The management of anovulatory infertility in women with polycystic ovary syndrome: an analysis of the evidence to support the development of global WHO guidance
- (2016) Adam H. Balen et al. HUMAN REPRODUCTION UPDATE
- Long-term Metformin Use and Vitamin B12 Deficiency in the Diabetes Prevention Program Outcomes Study
- (2016) Vanita R. Aroda et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Current understanding of metformin effect on the control of hyperglycemia in diabetes
- (2016) Hongying An et al. JOURNAL OF ENDOCRINOLOGY
- Liraglutide safety and efficacy in patients with non-alcoholic steatohepatitis (LEAN): a multicentre, double-blind, randomised, placebo-controlled phase 2 study
- (2016) Matthew James Armstrong et al. LANCET
- Effects of metformin on pregnancy outcomes in women with polycystic ovary syndrome
- (2016) Xian-Ling Zeng et al. MEDICINE
- Empagliflozin and Progression of Kidney Disease in Type 2 Diabetes
- (2016) Christoph Wanner et al. NEW ENGLAND JOURNAL OF MEDICINE
- The Effect of Metformin on Diastolic Function in Patients Presenting with ST-Elevation Myocardial Infarction
- (2016) Lawien Al Ali et al. PLoS One
- Prescription of oral antidiabetic drugs in Tyrol – Data from the Tyrol diabetes registry 2012–2015
- (2016) Lukas Lunger et al. WIENER KLINISCHE WOCHENSCHRIFT
- Repurposing metformin for cancer treatment: current clinical studies
- (2016) Young Kwang Chae et al. Oncotarget
- Diabetes treatments and risk of amputation, blindness, severe kidney failure, hyperglycaemia, and hypoglycaemia: open cohort study in primary care
- (2016) Julia Hippisley-Cox et al. BMJ-British Medical Journal
- Diabetes treatments and risk of amputation, blindness, severe kidney failure, hyperglycaemia, and hypoglycaemia: open cohort study in primary care
- (2016) Julia Hippisley-Cox et al. BMJ-British Medical Journal
- Repurposing metformin: an old drug with new tricks in its binding pockets
- (2015) R. Pryor et al. BIOCHEMICAL JOURNAL
- Selective Inhibition of Deactivated Mitochondrial Complex I by Biguanides
- (2015) Satoshi Matsuzaki et al. BIOCHEMISTRY
- Metformin Action: Concentrations Matter
- (2015) Ling He et al. Cell Metabolism
- Potential Impact of Prescribing Metformin According to eGFR Rather Than Serum Creatinine
- (2015) Delphine S. Tuot et al. DIABETES CARE
- Efficacy and Safety of Canagliflozin, a Sodium–Glucose Cotransporter 2 Inhibitor, as Add-on to Insulin in Patients With Type 1 Diabetes
- (2015) Robert R. Henry et al. DIABETES CARE
- Metformin versus insulin treatment in gestational diabetes in pregnancy in a developing country. A randomized control trial
- (2015) Jahanara Ainuddin et al. DIABETES RESEARCH AND CLINICAL PRACTICE
- Therapeutic Use of Metformin in Prediabetes and Diabetes Prevention
- (2015) Ulrike Hostalek et al. DRUGS
- Effect of Metformin Added to Insulin on Glycemic Control Among Overweight/Obese Adolescents With Type 1 Diabetes
- (2015) Ingrid M. Libman et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Metformin prevents renal interstitial fibrosis in mice with unilateral ureteral obstruction
- (2015) Rita C. Cavaglieri et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Metformin: A Novel but Controversial Drug in Cancer Prevention and Treatment
- (2015) Xinbing Sui et al. MOLECULAR PHARMACEUTICS
- Metformin activates a duodenal Ampk–dependent pathway to lower hepatic glucose production in rats
- (2015) Frank A Duca et al. NATURE MEDICINE
- Metformin reduces hyper-reactivity of platelets from patients with polycystic ovary syndrome by improving mitochondrial integrity
- (2015) Amro Elgheznawy et al. THROMBOSIS AND HAEMOSTASIS
- Association between guideline recommended drugs and death in older adults with multiple chronic conditions: population based cohort study
- (2015) Mary E Tinetti et al. BMJ-British Medical Journal
- Metformin Antagonizes Cancer Cell Proliferation by Suppressing Mitochondrial-Dependent Biosynthesis
- (2015) Takla Griss et al. PLOS BIOLOGY
- Association between guideline recommended drugs and death in older adults with multiple chronic conditions: population based cohort study
- (2015) Mary E Tinetti et al. BMJ-British Medical Journal
- Metformin Treatment in Type 2 Diabetes in Pregnancy: An Active Controlled, Parallel-Group, Randomized, Open Label Study in Patients with Type 2 Diabetes in Pregnancy
- (2015) Jahan Ara Ainuddin et al. Journal of Diabetes Research
- Metformin and Inflammation: Its Potential Beyond Glucose-lowering Effect
- (2015) Yoshifumi Saisho Endocrine Metabolic & Immune Disorders-Drug Targets
- Metformin Use in Kidney Transplant Recipients in the United States: An Observational Study
- (2015) Jenise Stephen et al. AMERICAN JOURNAL OF NEPHROLOGY
- Two weeks of metformin treatment induces AMPK-dependent enhancement of insulin-stimulated glucose uptake in mouse soleus muscle
- (2014) Jonas Møller Kristensen et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- AMPK/mTOR-mediated inhibition of survivin partly contributes to metformin-induced apoptosis in human gastric cancer cell
- (2014) Gang Han et al. CANCER BIOLOGY & THERAPY
- Metformin: From Mechanisms of Action to Therapies
- (2014) Marc Foretz et al. Cell Metabolism
- The Lysosomal v-ATPase-Ragulator Complex Is a Common Activator for AMPK and mTORC1, Acting as a Switch between Catabolism and Anabolism
- (2014) Chen-Song Zhang et al. Cell Metabolism
- Can people with type 2 diabetes live longer than those without? A comparison of mortality in people initiated with metformin or sulphonylurea monotherapy and matched, non-diabetic controls
- (2014) C. A. Bannister et al. DIABETES OBESITY & METABOLISM
- Mechanism of increase in plasma intact GLP-1 by metformin in type 2 diabetes: Stimulation of GLP-1 secretion or reduction in plasma DPP-4 activity?
- (2014) Tongzhi Wu et al. DIABETES RESEARCH AND CLINICAL PRACTICE
- Short-term intervention with liraglutide improved eating behavior in obese women with polycystic ovary syndrome
- (2014) Mojca Jensterle et al. ENDOCRINE RESEARCH
- What are the pharmacotherapy options for treating prediabetes?
- (2014) Giuseppe Daniele et al. EXPERT OPINION ON PHARMACOTHERAPY
- Low Concentrations of Metformin Suppress Glucose Production in Hepatocytes through AMP-activated Protein Kinase (AMPK)
- (2014) Jia Cao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Metformin—mode of action and clinical implications for diabetes and cancer
- (2014) Ida Pernicova et al. Nature Reviews Endocrinology
- Effects of low dose metformin in adolescents with type I diabetes mellitus: a randomized, double-blinded placebo-controlled study
- (2014) Kristen J Nadeau et al. PEDIATRIC DIABETES
- Comparative Effectiveness and Safety of Medications for Type 2 Diabetes: An Update Including New Drugs and 2-Drug Combinations
- (2013) Wendy L. Bennett et al. ANNALS OF INTERNAL MEDICINE
- Metformin and liraglutide ameliorate high glucose-induced oxidative stress via inhibition of PKC-NAD(P)H oxidase pathway in human aortic endothelial cells
- (2013) Battsetseg Batchuluun et al. ATHEROSCLEROSIS
- Haemoglobin A1c even within non-diabetic level is a predictor of cardiovascular disease in a general Japanese population: the Hisayama Study
- (2013) Fumie Ikeda et al. Cardiovascular Diabetology
- Chronic Metformin Treatment is Associated with Reduced Myocardial Infarct Size in Diabetic Patients with ST-segment Elevation Myocardial Infarction
- (2013) Chris P. H. Lexis et al. CARDIOVASCULAR DRUGS AND THERAPY
- Metformin Retards Aging in C. elegans by Altering Microbial Folate and Methionine Metabolism
- (2013) Filipe Cabreiro et al. CELL
- Comparative Safety and Effectiveness of Metformin in Patients With Diabetes Mellitus and Heart Failure
- (2013) Dean T. Eurich et al. Circulation-Heart Failure
- HbA1c and the Risks for All-Cause and Cardiovascular Mortality in the General Japanese Population: NIPPON DATA90
- (2013) M. Sakurai et al. DIABETES CARE
- The latest pharmacotherapy options for type 1 diabetes
- (2013) Johnny Ludvigsson EXPERT OPINION ON PHARMACOTHERAPY
- Multidrug and toxin extrusion proteins (MATE/SLC47); role in pharmacokinetics
- (2013) Frantisek Staud et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- AMPK, insulin resistance, and the metabolic syndrome
- (2013) Neil B. Ruderman et al. JOURNAL OF CLINICAL INVESTIGATION
- Association of B12 deficiency and clinical neuropathy with metformin use in type 2 diabetes patients
- (2013) AK Singh et al. Journal of Postgraduate Medicine
- Biguanides suppress hepatic glucagon signalling by decreasing production of cyclic AMP
- (2013) Russell A. Miller et al. NATURE
- Metformin Is Associated With Survival Benefit in Cancer Patients With Concurrent Type 2 Diabetes: A Systematic Review and Meta-Analysis
- (2013) M. Yin et al. ONCOLOGIST
- Metformin improves healthspan and lifespan in mice
- (2013) Alejandro Martin-Montalvo et al. Nature Communications
- Inappropriate metformin prescribing in elderly type 2 diabetes mellitus (T2DM) patients
- (2012) M Kosmalski et al. Advances in Medical Sciences
- Lymphocyte-suppressing and systemic anti-inflammatory effects of high-dose metformin in simvastatin-treated patients with impaired fasting glucose
- (2012) Robert Krysiak et al. ATHEROSCLEROSIS
- Loss of multidrug and toxin extrusion 1 (MATE1) is associated with metformin-induced lactic acidosis
- (2012) K Toyama et al. BRITISH JOURNAL OF PHARMACOLOGY
- Effects of metformin on markers of oxidative stress and antioxidant reserve in patients with newly diagnosed type 2 diabetes: A randomized clinical trial
- (2012) Alireza Esteghamati et al. CLINICAL NUTRITION
- The Effect of Novel Promoter Variants in MATE1 and MATE2 on the Pharmacokinetics and Pharmacodynamics of Metformin
- (2012) S L Stocker et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Glucose perturbations and cardiovascular risk: Challenges and opportunities
- (2012) Lars Rydén et al. Diabetes & Vascular Disease Research
- Effects of Metformin Versus Glipizide on Cardiovascular Outcomes in Patients With Type 2 Diabetes and Coronary Artery Disease
- (2012) J. Hong et al. DIABETES CARE
- Effects of chronic treatment with metformin on dipeptidyl peptidase-4 activity, glucagon-like peptide 1 and ghrelin in obese patients with Type 2 diabetes mellitus
- (2012) S. K. Thondam et al. DIABETIC MEDICINE
- The effect of metformin on monocyte secretory function in simvastatin-treated patients with impaired fasting glucose
- (2012) Robert Krysiak et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Metformin pathways
- (2012) Li Gong et al. Pharmacogenetics and Genomics
- Investigating Metformin for Cancer Prevention and Treatment: The End of the Beginning
- (2012) Michael N. Pollak Cancer Discovery
- Metformin kills and radiosensitizes cancer cells and preferentially kills cancer stem cells
- (2012) Chang W. Song et al. Scientific Reports
- Effectiveness and safety of metformin in 51 675 patients with type 2 diabetes and different levels of renal function: a cohort study from the Swedish National Diabetes Register
- (2012) Nils Ekström et al. BMJ Open
- Reappraisal of Metformin Efficacy in the Treatment of Type 2 Diabetes: A Meta-Analysis of Randomised Controlled Trials
- (2012) Rémy Boussageon et al. PLOS MEDICINE
- Effects of lifestyle modification and metformin on atherosclerotic indices among HIV-infected patients with the metabolic syndrome
- (2011) Kathleen Fitch et al. AIDS
- Enhancing AMPK activation during ischemia protects the diabetic heart against reperfusion injury
- (2011) Marta A. Paiva et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Metformin, Independent of AMPK, Induces mTOR Inhibition and Cell-Cycle Arrest through REDD1
- (2011) I. Ben Sahra et al. CANCER RESEARCH
- Metformin attenuates streptozotocin-induced diabetic nephropathy in rats through modulation of oxidative stress genes expression
- (2011) Abdulqader A. Alhaider et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Profibrinolytic, Antithrombotic, and Antiinflammatory Effects of an Insulin-Sensitizing Strategy in Patients in the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) Trial
- (2011) Burton E. Sobel et al. CIRCULATION
- Association of Biochemical B12 Deficiency With Metformin Therapy and Vitamin B12 Supplements: The National Health and Nutrition Examination Survey, 1999-2006
- (2011) L. Reinstatler et al. DIABETES CARE
- Metformin therapy and prognosis of patients with heart failure and new-onset diabetes mellitus. A propensity-matched study in the community
- (2011) Sotero P. Romero et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- The role of insulin-sensitizing agents in the treatment of nonalcoholic steatohepatitis
- (2011) Lisa B. Van Wagner et al. Therapeutic Advances in Gastroenterology
- Metformin Use and Mortality Among Patients With Diabetes and AtherothrombosisMetformin Use With Diabetes and Atherothrombosis
- (2010) Ronan Roussel ARCHIVES OF INTERNAL MEDICINE
- Metformin and Cancer Risk in Diabetic Patients: A Systematic Review and Meta-analysis
- (2010) A. DeCensi et al. Cancer Prevention Research
- Metformin: A Therapeutic Opportunity in Breast Cancer
- (2010) A. M. Gonzalez-Angulo et al. CLINICAL CANCER RESEARCH
- Diabetes and Cancer: A consensus report
- (2010) E. Giovannucci et al. DIABETES CARE
- Effect of metformin on cardiovascular events and mortality: a meta-analysis of randomized clinical trials
- (2010) C. Lamanna et al. DIABETES OBESITY & METABOLISM
- The use of metformin in type 1 diabetes: a systematic review of efficacy
- (2010) S. Vella et al. DIABETOLOGIA
- Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state
- (2010) Marc Foretz et al. JOURNAL OF CLINICAL INVESTIGATION
- New aspects of HbA1c as a risk factor for cardiovascular diseases in type 2 diabetes: an observational study from the Swedish National Diabetes Register (NDR)
- (2010) K. Eeg-Olofsson et al. JOURNAL OF INTERNAL MEDICINE
- Long-term effect of metformin on blood glucose control in non-obese patients with type 2 diabetes mellitus
- (2010) Hiroyuki Ito et al. Nutrition & Metabolism
- Long-term Effects of Metformin on Metabolism and Microvascular and Macrovascular Disease in Patients With Type 2 Diabetes Mellitus
- (2009) Adriaan Kooy et al. ARCHIVES OF INTERNAL MEDICINE
- Metformin Selectively Targets Cancer Stem Cells, and Acts Together with Chemotherapy to Block Tumor Growth and Prolong Remission
- (2009) H. A. Hirsch et al. CANCER RESEARCH
- New Users of Metformin Are at Low Risk of Incident Cancer: A cohort study among people with type 2 diabetes
- (2009) G. Libby et al. DIABETES CARE
- Metformin Associated With Lower Cancer Mortality in Type 2 Diabetes: ZODIAC-16
- (2009) G. W.D. Landman et al. DIABETES CARE
- Biguanides and thiazolidinediones inhibit stimulated lipolysis in human adipocytes through activation of AMP-activated protein kinase
- (2009) O. Bourron et al. DIABETOLOGIA
- Evidence-Based and Potential Benefits of Metformin in the Polycystic Ovary Syndrome: A Comprehensive Review
- (2009) Stefano Palomba et al. ENDOCRINE REVIEWS
- Metformin and Pathologic Complete Responses to Neoadjuvant Chemotherapy in Diabetic Patients With Breast Cancer
- (2009) Sao Jiralerspong et al. JOURNAL OF CLINICAL ONCOLOGY
- Genetic variation in the organic cation transporter 1 is associated with metformin response in patients with diabetes mellitus
- (2009) M L Becker et al. PHARMACOGENOMICS JOURNAL
- The Hemoglobin A1c Level as a Progressive Risk Factor for Cardiovascular Death, Hospitalization for Heart Failure, or Death in Patients With Chronic Heart Failure
- (2008) Hertzel C. Gerstein ARCHIVES OF INTERNAL MEDICINE
- Cardiovascular Outcomes in Trials of Oral Diabetes Medications
- (2008) Elizabeth Selvin et al. ARCHIVES OF INTERNAL MEDICINE
- Activation of AMP-Activated Protein Kinase by Metformin Improves Left Ventricular Function and Survival in Heart Failure
- (2008) Susheel Gundewar et al. CIRCULATION RESEARCH
- Metformin, Sulfonylureas, or Other Antidiabetes Drugs and the Risk of Lactic Acidosis or Hypoglycemia: A nested case-control analysis
- (2008) M. Bodmer et al. DIABETES CARE
- Glycated Haemoglobin and Cardiovascular Outcomes in People with Type 2 Diabetes: A Large Prospective Cohort Study
- (2008) CR Elley et al. DIABETIC MEDICINE
- Metformin and the intestine
- (2008) C. J. Bailey et al. DIABETOLOGIA
- Metformin versus Insulin for the Treatment of Gestational Diabetes
- (2008) Janet A. Rowan et al. NEW ENGLAND JOURNAL OF MEDICINE
- 10-Year Follow-up of Intensive Glucose Control in Type 2 Diabetes
- (2008) Rury R. Holman et al. NEW ENGLAND JOURNAL OF MEDICINE
- Effect of Adjunct Metformin Treatment in Patients with Type-1 Diabetes and Persistent Inadequate Glycaemic Control. A Randomized Study
- (2008) Søren Søgaard Lund et al. PLoS One
- AMPK: a metabolic gauge regulating whole-body energy homeostasis
- (2008) Ricardo Lage et al. TRENDS IN MOLECULAR MEDICINE
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