Ni-catalyzed enantioselective [2 + 2 + 2] cycloaddition of malononitriles with alkynes

Chiral Aluminum-Controlled Ni-catalyzed Enantioselective Synthesis of Indenes via C−CN Bond Activation

(2020) Tao Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Assembly of Cycloenones with a Nitrile-Containing All-Carbon Quaternary Center from Malononitriles Enabled by Ni Catalysis

(2020) Zhiwu Lu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Divergent Synthesis of Densely Substituted Arenes and Pyridines via Cyclotrimerization Reactions of Alkynyl Triazenes

(2019) Jin-Fay Tan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Phosphite-Catalyzed C−H Allylation of Azaarenes via an Enantioselective [2,3]-Aza-Wittig Rearrangement

(2019) Abdul Motaleb et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Synthesis of Heterocyclic γ-Amino-Acid and Diamine Derivatives by Three-Component Radical Cascade Reactions

(2019) Danqing Zheng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ni-Catalyzed Reductive Cyanation of Aryl Halides and Phenol Derivatives via Transnitrilation

(2019) L. Reginald Mills et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Sequence-Dependent Stereodivergent Allylic Alkylation/Fluorination of Acyclic Ketones

(2019) Xi-Jia Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Stereoselective arene formation

(2018) Achim Link et al.   CHEMICAL SOCIETY REVIEWS

Renaissance of pyridine-oxazolines as chiral ligands for asymmetric catalysis

(2018) Guoqiang Yang et al.   CHEMICAL SOCIETY REVIEWS

Conjugate Addition–Enantioselective Protonation of N-Aryl Glycines to α-Branched 2-Vinylazaarenes via Cooperative Photoredox and Asymmetric Catalysis

(2018) Yanli Yin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic enantioselective Minisci-type addition to heteroarenes

(2018) Rupert S. J. Proctor et al.   SCIENCE

Comprehensive Study of the Reactions Between Chelating Phosphines and Ni(cod)2

(2018) Andrew L. Clevenger et al.   ORGANOMETALLICS

A survey of the role of nitrile groups in protein–ligand interactions

(2018) Yuanxun Wang et al.   Future Medicinal Chemistry

Asymmetric Suzuki-Miyaura coupling of heterocycles via Rhodium-catalysed allylic arylation of racemates

(2017) Philipp Schäfer et al.   Nature Communications

Catalytic Enantioselective Desymmetrization Reactions to All-Carbon Quaternary Stereocenters

(2016) Xing-Ping Zeng et al.   CHEMICAL REVIEWS

Nickel-Catalyzed [2+2+2] Cycloaddition of Alkyne-Nitriles with Alkynes Assisted by Lewis Acids: Efficient Synthesis of Fused Pyridines

(2016) Xu You et al.   CHEMISTRY-A EUROPEAN JOURNAL

Asymmetric Hydroarylation of Vinylarenes Using a Synergistic Combination of CuH and Pd Catalysis

(2016) Stig D. Friis et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of δ- and α-Carbolines via Nickel-Catalyzed [2 + 2 + 2] Cycloaddition of Functionalized Alkyne-Nitriles with Alkynes

(2016) Gaonan Wang et al.   ORGANIC LETTERS

Rhodium-Catalyzed Atroposelective [2 + 2 + 2] Cycloaddition of Ortho-Substituted Phenyl Diynes with Nitriles: Effect of Ortho Substituents on Regio- and Enantioselectivity

(2016) Kenichi Kashima et al.   ORGANIC LETTERS

Coupling Catalytic Alkene Hydroacylation and α-Arylation: Enantioselective Synthesis of Heterocyclic Ketones with α-Chiral Quaternary Stereocenters

(2016) Avipsa Ghosh et al.   ACS Catalysis

Advances in Nickel-Catalyzed Cycloaddition Reactions To Construct Carbocycles and Heterocycles

(2015) Ashish Thakur et al.   ACCOUNTS OF CHEMICAL RESEARCH

Catalytic Enantioselective Construction of Quaternary Stereocenters: Assembly of Key Building Blocks for the Synthesis of Biologically Active Molecules

(2015) Yiyang Liu et al.   ACCOUNTS OF CHEMICAL RESEARCH

Synthesis of Pyridylphosphonates by Rhodium-Catalyzed [2+2+2] Cycloaddition of 1,6- and 1,7-Diynes with Diethyl Phosphorocyanidate

(2015) Kenichi Kashima et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Fundamental Studies and Development of Nickel-Catalyzed Trifluoromethylthiolation of Aryl Chlorides: Active Catalytic Species and Key Roles of Ligand and Traceless MeCN Additive Revealed

(2015) Guoyin Yin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis, mechanism of formation, and catalytic activity of Xantphos nickel π-complexes

(2014) Nicholas D. Staudaher et al.   CHEMICAL COMMUNICATIONS

Metal-Free Multicomponent Syntheses of Pyridines

(2014) Christophe Allais et al.   CHEMICAL REVIEWS

Enantioselective C–H Bond Addition of Pyridines to Alkenes Catalyzed by Chiral Half-Sandwich Rare-Earth Complexes

(2014) Guoyong Song et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Transition Metal-Mediated Synthesis of Monocyclic Aromatic Heterocycles

(2013) Anton V. Gulevich et al.   CHEMICAL REVIEWS

Mechanistic Evaluation of the Ni(IPr)2-Catalyzed Cycloaddition of Alkynes and Nitriles To Afford Pyridines: Evidence for the Formation of a Key η1-Ni(IPr)2(RCN) Intermediate

(2013) Ryan M. Stolley et al.   ORGANOMETALLICS

2-Methyltetrahydrofuran (2-MeTHF): A Biomass-Derived Solvent with Broad Application in Organic Chemistry

(2012) Vittorio Pace et al.   ChemSusChem

Iridium-Catalyzed [2 + 2 + 2] Cycloaddition of α,ω-Diynes with Nitriles

(2012) Gen Onodera et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Discovery of [Ni(NHC)RCN]2 Species and Their Role as Cycloaddition Catalysts for the Formation of Pyridines

(2012) Ryan M. Stolley et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Simple and Highly Efficient Iron Catalyst for a [2+2+2] Cycloaddition to Form Pyridines

(2011) Chunxiang Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Serendipitous Discovery: Nickel Catalyst for the Cycloaddition of Diynes with Unactivated Nitriles

(2011) Puneet Kumar et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nickel-Catalyzed Asymmetric α-Arylation and Heteroarylation of Ketones with Chloroarenes: Effect of Halide on Selectivity, Oxidation State, and Room-Temperature Reactions

(2011) Shaozhong Ge et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Construction of fused heterocycles by metal-mediated [2+2+2] cyclotrimerization of alkynes and/or nitriles

(2011) Mohamed R. Shaaban et al.   TETRAHEDRON

Recent Strategies for the Synthesis of Pyridine Derivatives

(2010) Matthew D. Hill   CHEMISTRY-A EUROPEAN JOURNAL

Nitrile-Containing Pharmaceuticals: Efficacious Roles of the Nitrile Pharmacophore

(2010) Fraser F. Fleming et al.   JOURNAL OF MEDICINAL CHEMISTRY

Asymmetric Synthesis of Axially Chiral 1-Aryl-5,6,7,8-tetrahydroquinolines by Cobalt-Catalyzed [2 + 2 + 2] Cycloaddition Reaction of 1-Aryl-1,7-octadiynes and Nitriles

(2010) Marko Hapke et al.   JOURNAL OF ORGANIC CHEMISTRY

Nitrile Ligated Transition Metal Complexes with Weakly Coordinating Counteranions and Their Catalytic Applications

(2009) Silvana F. Rach et al.   CHEMICAL REVIEWS

Escape from Flatland: Increasing Saturation as an Approach to Improving Clinical Success

(2009) Frank Lovering et al.   JOURNAL OF MEDICINAL CHEMISTRY

Palladium-Catalyzed Regio-, Diastereo-, and Enantioselective Benzylic Allylation of 2-Substituted Pyridines

(2009) Barry M. Trost et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Aluminum-Catalyzed Asymmetric Alkylations of Pyridyl-Substituted Alkynyl Ketones with Dialkylzinc Reagents

(2008) Donna K. Friel et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY