标题
HBV-Integration Studies in the Clinic: Role in the Natural History of Infection
作者
关键词
-
出版物
Viruses-Basel
Volume 13, Issue 3, Pages 368
出版商
MDPI AG
发表日期
2021-02-26
DOI
10.3390/v13030368
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- SurVirus: a repeat-aware virus integration caller
- (2021) Ramesh Rajaby et al. NUCLEIC ACIDS RESEARCH
- Hepatitis B virus integrations promote local and distant oncogenic driver alterations in hepatocellular carcinoma
- (2021) Camille Péneau et al. GUT
- Can we cure hepatitis B virus with novel direct‐acting antivirals?
- (2020) Maria G. Martinez et al. LIVER INTERNATIONAL
- The evolution and clinical impact of hepatitis B virus genome diversity
- (2020) Peter A. Revill et al. Nature Reviews Gastroenterology & Hepatology
- Direct-acting antivirals and viral RNA targeting for hepatitis B cure
- (2020) Janine French et al. Current Opinion in HIV and AIDS
- Occult hepatitis B infection and hepatocellular carcinoma: Epidemiology, virology, hepatocarcinogenesis and clinical significance
- (2020) Lung-Yi Mak et al. JOURNAL OF HEPATOLOGY
- Targeted long read sequencing reveals the comprehensive architecture and expression patterns of integrated HBV DNA in CHB liver biopsies
- (2020) Ricardo Ramirez et al. JOURNAL OF HEPATOLOGY
- Abundance of Noncircular Intrahepatic Hepatitis B Virus DNA May Reflect Frequent Integration Into Human DNA in Chronically Infected Patients
- (2020) Gustaf E Rydell et al. JOURNAL OF INFECTIOUS DISEASES
- Whole exome HBV DNA integration is independent of the intrahepatic HBV reservoir in HBeAg-negative chronic hepatitis B
- (2020) Valentina Svicher et al. GUT
- Update of the statements on biology and clinical impact of occult hepatitis b virus infection
- (2019) Giovanni Raimondo et al. JOURNAL OF HEPATOLOGY
- Hepatitis B Surface Antigen Activates Unfolded Protein Response in Forming Ground Glass Hepatocytes of Chronic Hepatitis B
- (2019) Yao Li et al. Viruses-Basel
- Retrotransposon elements among initial sites of hepatitis B virus integration into human genome in the HepG2-NTCP cell infection model
- (2019) Ranjit Chauhan et al. Cancer Genetics
- Among Patients with Undetectable Hepatitis B Surface Antigen and Hepatocellular Carcinoma, a High Proportion Has Integration of HBV DNA into Hepatocyte DNA and No Cirrhosis
- (2019) Danny Ka-Ho Wong et al. Clinical Gastroenterology and Hepatology
- Genomic modeling of hepatitis B virus integration frequency in the human genome
- (2019) Ondrej Podlaha et al. PLoS One
- Understanding the Natural History of Hepatitis B Virus Infection and the New Definitions of Cure and the Endpoints of Clinical Trials
- (2019) Alisa Likhitsup et al. Clinics in Liver Disease
- Therapeutic strategies for hepatitis B virus infection: towards a cure
- (2019) Gregory C. Fanning et al. NATURE REVIEWS DRUG DISCOVERY
- Guidance for design and endpoints of clinical trials in chronic hepatitis B - Report from the 2019 EASL-AASLD HBV Treatment Endpoints Conference
- (2019) Markus Cornberg et al. JOURNAL OF HEPATOLOGY
- Liver sampling: a vital window into HBV pathogenesis on the path to functional cure
- (2018) Upkar S Gill et al. GUT
- Integration of hepatitis B virus S gene impacts on hepatitis B surface antigen levels in patients with antiviral therapy
- (2018) Bobin Hu et al. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
- Integration of hepatitis B virus DNA in chronically infected patients assessed by Alu-PCR
- (2018) Simon B. Larsson et al. JOURNAL OF MEDICAL VIROLOGY
- Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles
- (2018) Thomas Tu et al. JOURNAL OF VIROLOGY
- Whole-exome sequencing reveals the origin and evolution of hepato-cholangiocarcinoma
- (2018) Anqiang Wang et al. Nature Communications
- Hepatitis B virus infection
- (2018) Man-Fung Yuen et al. Nature Reviews Disease Primers
- Sequence analysis of integrated hepatitis B virus DNA during HBeAg-seroconversion
- (2018) Magdalena Agnieszka Budzinska et al. Emerging Microbes & Infections
- Cellular Genomic Sites of Hepatitis B Virus DNA Integration
- (2018) Magdalena A. Budzinska et al. Genes
- Role of humoral immunity against hepatitis B virus core antigen in the pathogenesis of acute liver failure
- (2018) Zhaochun Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cyclin A2/E1 activation defines a hepatocellular carcinoma subclass with a rearrangement signature of replication stress
- (2018) Quentin Bayard et al. Nature Communications
- Proliferation of primary human hepatocytes and prevention of hepatitis B virus reinfection efficiently deplete nuclear cccDNA in vivo
- (2017) Lena Allweiss et al. GUT
- Reduction of covalently closed circular DNA with long-term nucleos(t)ide analogue treatment in chronic hepatitis B
- (2017) Ching-Lung Lai et al. JOURNAL OF HEPATOLOGY
- EASL 2017 Clinical Practice Guidelines on the management of hepatitis B virus infection
- (2017) Pietro Lampertico et al. JOURNAL OF HEPATOLOGY
- Global, regional, and national age-sex specific mortality for 264 causes of death, 1980–2016: a systematic analysis for the Global Burden of Disease Study 2016
- (2017) Mohsen Naghavi et al. LANCET
- Mobile DNA in Health and Disease
- (2017) Haig H. Kazazian et al. NEW ENGLAND JOURNAL OF MEDICINE
- RNAi-based treatment of chronically infected patients and chimpanzees reveals that integrated hepatitis B virus DNA is a source of HBsAg
- (2017) Christine I. Wooddell et al. Science Translational Medicine
- Immune Tolerant Chronic Hepatitis B: The Unrecognized Risks
- (2017) Patrick Kennedy et al. Viruses-Basel
- HBV DNA Integration: Molecular Mechanisms and Clinical Implications
- (2017) Thomas Tu et al. Viruses-Basel
- Seven-Year Treatment Outcome of Entecavir in a Real-World Cohort: Effects on Clinical Parameters, HBsAg and HBcrAg Levels
- (2017) Yuk-Fai Lam et al. Clinical and Translational Gastroenterology
- HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant
- (2016) William S. Mason et al. GASTROENTEROLOGY
- Hepatitis B Virus–Specific and Global T-Cell Dysfunction in Chronic Hepatitis B
- (2016) Jang-June Park et al. GASTROENTEROLOGY
- Maternal-Derived Hepatitis B Virus e Antigen Alters Macrophage Function in Offspring to Drive Viral Persistence after Vertical Transmission
- (2016) Yongjun Tian et al. IMMUNITY
- High antigen levels induce an exhausted phenotype in a chronic infection without impairing T cell expansion and survival
- (2016) Daniel T. Utzschneider et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Hepatitis B virus-human chimeric transcript HBx-LINE1 promotes hepatic injury via sequestering cellular microRNA-122
- (2016) Hong-Wei Liang et al. JOURNAL OF HEPATOLOGY
- Hepatitis B virus X protein identifies the Smc5/6 complex as a host restriction factor
- (2016) Adrien Decorsière et al. NATURE
- Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer
- (2016) Akihiro Fujimoto et al. NATURE GENETICS
- Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma
- (2016) Ling-Hao Zhao et al. Nature Communications
- Hepatitis B Virus X and Regulation of Viral Gene Expression
- (2016) Betty L. Slagle et al. Cold Spring Harbor Perspectives in Medicine
- Host–virus interactions in hepatitis B virus infection
- (2015) Luca G Guidotti et al. CURRENT OPINION IN IMMUNOLOGY
- DNA methylation at hepatitis B viral integrants is associated with methylation at flanking human genomic sequences
- (2015) Yoshiyuki Watanabe et al. GENOME RESEARCH
- HBV cccDNA: viral persistence reservoir and key obstacle for a cure of chronic hepatitis B
- (2015) Michael Nassal GUT
- Hepatitis B virus pre-S2mutant large surface protein inhibits DNA double-strand break repair and leads to genome instability in hepatocarcinogenesis
- (2015) Yi-Hsuan Hsieh et al. JOURNAL OF PATHOLOGY
- Clonal expansion of hepatocytes with a selective advantage occurs during all stages of chronic hepatitis B virus infection
- (2015) T. Tu et al. JOURNAL OF VIRAL HEPATITIS
- Hepatitis B virus (HBV) DNA integration in patients with occult HBV infection and hepatocellular carcinoma
- (2015) Carlo Saitta et al. LIVER INTERNATIONAL
- Molecular biology of hepatitis B virus infection
- (2015) Christoph Seeger et al. VIROLOGY
- Viral-Human Chimeric Transcript Predisposes Risk to Liver Cancer Development and Progression
- (2014) Chi-Chiu Lau et al. CANCER CELL
- Hepatic Immune Regulation and Its Involvement in Viral Hepatitis Infection
- (2014) Percy A. Knolle et al. GASTROENTEROLOGY
- Authors’ response: virus–host interactions in HBV-related hepatocellular carcinoma: more to be revealed?
- (2014) Qian Cao et al. GUT
- Telomerase reverse transcriptase promoter mutation is an early somatic genetic alteration in the transformation of premalignant nodules in hepatocellular carcinoma on cirrhosis
- (2014) Jean Charles Nault et al. HEPATOLOGY
- Envelope Proteins Derived from Naturally Integrated Hepatitis B Virus DNA Support Assembly and Release of Infectious Hepatitis Delta Virus Particles
- (2014) N. Freitas et al. JOURNAL OF VIROLOGY
- Preserved T-Cell Function in Children and Young Adults With Immune-Tolerant Chronic Hepatitis B
- (2012) Patrick T.F. Kennedy et al. GASTROENTEROLOGY
- The effects of hepatitis B virus integration into the genomes of hepatocellular carcinoma patients
- (2012) Z. Jiang et al. GENOME RESEARCH
- Impact of hepatitis B virus (HBV) preS/S genomic variability on HBV surface antigen and HBV DNA serum levels
- (2012) Teresa Pollicino et al. HEPATOLOGY
- Hepatitis B virus DNA integration in tumour tissue of a non-cirrhotic HFE-haemochromatosis patient with hepatocellular carcinoma
- (2012) Teresa Pollicino et al. JOURNAL OF HEPATOLOGY
- Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators
- (2012) Akihiro Fujimoto et al. NATURE GENETICS
- Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma
- (2012) Wing-Kin Sung et al. NATURE GENETICS
- A Large Population Histology Study Showing the Lack of Association between ALT Elevation and Significant Fibrosis in Chronic Hepatitis B
- (2012) Wai-Kay Seto et al. PLoS One
- Occult HBV infection
- (2012) Giovanni Raimondo et al. Seminars in Immunopathology
- Recurrent Targeted Genes of Hepatitis B Virus in the Liver Cancer Genomes Identified by a Next-Generation Sequencing–Based Approach
- (2012) Dong Ding et al. PLoS Genetics
- Hepatocellular carcinoma: the point of view of the hepatitis B virus
- (2011) T. Pollicino et al. CARCINOGENESIS
- Innate and adaptive immune responses in chronic hepatitis B virus infections: towards restoration of immune control of viral infection
- (2011) Antonio Bertoletti et al. GUT
- Hepatitis B virus x protein in the pathogenesis of hepatitis B virus-induced hepatocellular carcinoma
- (2011) Michael C Kew JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
- Hepatitis B surface antigen quantification: Why and how to use it in 2011 – A core group report
- (2011) Henry Lik-Yuen Chan et al. JOURNAL OF HEPATOLOGY
- Hepatitis B virus X protein is essential to initiate and maintain virus replication after infection
- (2011) Julie Lucifora et al. JOURNAL OF HEPATOLOGY
- T cell responses and viral variability in blood donation candidates with occult hepatitis B infection
- (2011) Marta Bes et al. JOURNAL OF HEPATOLOGY
- Natural History of Chronic Hepatitis B
- (2010) Brian J. McMahon Clinics in Liver Disease
- Molecular events in hepatic preneoplasia: A review
- (2010) S.W. French EXPERIMENTAL AND MOLECULAR PATHOLOGY
- Hepatitis B: The virus and disease
- (2010) T. Jake Liang HEPATOLOGY
- Serum hepatitis B surface antigen and hepatitis B e antigen titers: Disease phase influences correlation with viral load and intrahepatic hepatitis B virus markers
- (2010) Alexander J.V. Thompson et al. HEPATOLOGY
- Hepatitis B surface antigen levels during the natural history of chronic hepatitis B: A perspective on Asia
- (2010) Tin Nguyen et al. JOURNAL OF HEPATOLOGY
- Hepatitis B surface antigen: Relation to hepatitis B replication parameters in HBeAg-negative chronic hepatitis B
- (2010) Emanuel K. Manesis et al. JOURNAL OF HEPATOLOGY
- Relationship between serum hepatitis B virus DNA and surface antigen with covalently closed circular DNA in HBeAg-negative patients
- (2010) L.Y. Lin et al. JOURNAL OF MEDICAL VIROLOGY
- Clonal Expansion of Normal-Appearing Human Hepatocytes during Chronic Hepatitis B Virus Infection
- (2010) W. S. Mason et al. JOURNAL OF VIROLOGY
- The C-terminal region of the hepatitis B virus X protein is essential for its stability and function
- (2010) Rebecca A. Lizzano et al. VIRUS RESEARCH
- Integrative Transcriptome Analysis Reveals Common Molecular Subclasses of Human Hepatocellular Carcinoma
- (2009) Y. Hoshida et al. CANCER RESEARCH
- Control of cccDNA function in hepatitis B virus infection
- (2009) Massimo Levrero et al. JOURNAL OF HEPATOLOGY
- The Size of the Viral Inoculum Contributes to the Outcome of Hepatitis B Virus Infection
- (2009) S. Asabe et al. JOURNAL OF VIROLOGY
- Nuclear HBx binds the HBV minichromosome and modifies the epigenetic regulation of cccDNA function
- (2009) L. Belloni et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- COOH-Terminal Truncated HBV X Protein Plays Key Role in Hepatocarcinogenesis
- (2008) N.-F. Ma et al. CLINICAL CANCER RESEARCH
- The Characteristics of the Cell-Mediated Immune Response Identify Different Profiles of Occult Hepatitis B Virus Infection
- (2008) Alessandro Zerbini et al. GASTROENTEROLOGY
- Ground glass hepatocytes contain pre-S mutants and represent preneoplastic lesions in chronic hepatitis B virus infection
- (2008) Ih-Jen Su et al. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
- The global impact of vaccination against hepatitis B: A historical overview
- (2008) Alessandro R. Zanetti et al. VACCINE
- Impact of hepatitis B virus (HBV) X gene integration in liver tissue on hepatocellular carcinoma development in serologically HBV-negative chronic hepatitis C patients
- (2007) Hidenori Toyoda et al. JOURNAL OF HEPATOLOGY
- Natural history of chronic hepatitis B: Special emphasis on disease progression and prognostic factors
- (2007) Giovanna Fattovich et al. JOURNAL OF HEPATOLOGY
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started