Hepatitis B virus integrations promote local and distant oncogenic driver alterations in hepatocellular carcinoma

The landscape of viral associations in human cancers

(2020) Marc Zapatka et al.   NATURE GENETICS

HBV‐ TERT Promoter Integration Harnesses Host ELF4 Resulting in TERT Gene Transcription in Hepatocellular Carcinoma

(2020) Karen Man‐Fong Sze et al.   HEPATOLOGY

A review on hepatitis D: from virology to new therapies

(2019) Nathalie Mentha et al.   Journal of Advanced Research

Analysis of Liver Cancer Cell Lines Identifies Agents With Likely Efficacy Against Hepatocellular Carcinoma and Markers of Response

(2019) Stefano Caruso et al.   GASTROENTEROLOGY

Global Elimination of Chronic Hepatitis

(2019) David L. Thomas   NEW ENGLAND JOURNAL OF MEDICINE

Clinical impact of genomic diversity from early to advanced hepatocellular carcinoma

(2019) Jean-Charles Nault et al.   HEPATOLOGY

Adeno-associated virus in the liver: natural history and consequences in tumour development

(2019) Tiziana La Bella et al.   GUT

A global view of hepatocellular carcinoma: trends, risk, prevention and management

(2019) Ju Dong Yang et al.   Nature Reviews Gastroenterology & Hepatology

BAP1 mutations define a homogeneous subgroup of hepatocellular carcinoma with fibrolamellar-like features and activated PKA

(2019) Théo Z. Hirsch et al.   JOURNAL OF HEPATOLOGY

Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles

(2018) Thomas Tu et al.   JOURNAL OF VIROLOGY

Characterization of HBV integration patterns and timing in liver cancer and HBV-infected livers

(2018) Mayuko Furuta et al.   Oncotarget

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Androgen Receptor Enhances Hepatic TERT Transcription after Hepatitis B Virus Integration or Point Mutation in Promoter Region

(2018) Chiao-Ling Li et al.   HEPATOLOGY

Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma

(2018) Liu Yang et al.   Journal of Cancer

Sequence analysis of integrated hepatitis B virus DNA during HBeAg-seroconversion

(2018) Magdalena Agnieszka Budzinska et al.   Emerging Microbes & Infections

Cyclin A2/E1 activation defines a hepatocellular carcinoma subclass with a rearrangement signature of replication stress

(2018) Quentin Bayard et al.   Nature Communications

HBV DNA Integration: Molecular Mechanisms and Clinical Implications

(2017) Thomas Tu et al.   Viruses-Basel

HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant

(2016) William S. Mason et al.   GASTROENTEROLOGY

Mechanisms of HBV-induced hepatocellular carcinoma

(2016) Massimo Levrero et al.   JOURNAL OF HEPATOLOGY

Overview of hepatitis B viral replication and genetic variability

(2016) Shuping Tong et al.   JOURNAL OF HEPATOLOGY

Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma

(2016) Ling-Hao Zhao et al.   Nature Communications

Characterization of the genotype and integration patterns of hepatitis B virus in early- and late-onset hepatocellular carcinoma

(2015) Hongli Yan et al.   HEPATOLOGY

Risk of hepatocellular carcinoma in chronic hepatitis B: Assessment and modification with current antiviral therapy

(2015) George V. Papatheodoridis et al.   JOURNAL OF HEPATOLOGY

Conceptual models for the initiation of hepatitis B virus-associated hepatocellular carcinoma

(2015) Thomas Tu et al.   LIVER INTERNATIONAL

Integrative analysis of 111 reference human epigenomes

(2015) Anshul Kundaje et al.   NATURE

Recurrent AAV2-related insertional mutagenesis in human hepatocellular carcinomas

(2015) Jean-Charles Nault et al.   NATURE GENETICS

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

Identification of HBV-MLL4 Integration and Its Molecular Basis in Chinese Hepatocellular Carcinoma

(2015) Hua Dong et al.   PLoS One

Association of Nucleos(t)ide Analogue Therapy With Reduced Risk of Hepatocellular Carcinoma in Patients With Chronic Hepatitis B—A Nationwide Cohort Study

(2014) Chun-Ying Wu et al.   GASTROENTEROLOGY

Integration of tumour and viral genomic characterisations in HBV-related hepatocellular carcinomas

(2014) Giuliana Amaddeo et al.   GUT

Trans-ancestry mutational landscape of hepatocellular carcinoma genomes

(2014) Yasushi Totoki et al.   NATURE GENETICS

Clinical implications of hepatitis B virus mutations: Recent advances

(2014) Ivana Lazarevic   WORLD JOURNAL OF GASTROENTEROLOGY

Entecavir treatment reduces hepatic events and deaths in chronic hepatitis B patients With liver cirrhosis

(2013) Grace Lai-Hung Wong et al.   HEPATOLOGY

The function of targeted host genes determines the oncogenicity of HBV integration in hepatocellular carcinoma

(2013) Xiaojun Li et al.   JOURNAL OF HEPATOLOGY

Long-term entecavir treatment reduces hepatocellular carcinoma incidence in patients with hepatitis B virus infection

(2012) Tetsuya Hosaka et al.   HEPATOLOGY

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators

(2012) Akihiro Fujimoto et al.   NATURE GENETICS

Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma

(2012) Wing-Kin Sung et al.   NATURE GENETICS