RNAi-based treatment of chronically infected patients and chimpanzees reveals that integrated hepatitis B virus DNA is a source of HBsAg

Reduction of covalently closed circular DNA with long-term nucleos(t)ide analogue treatment in chronic hepatitis B

(2017) Ching-Lung Lai et al.   JOURNAL OF HEPATOLOGY

Chronic Hepatitis B Virus Infection

(2016) Man-Fung Yuen et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

Clonal expansion of hepatocytes with a selective advantage occurs during all stages of chronic hepatitis B virus infection

(2015) T. Tu et al.   JOURNAL OF VIRAL HEPATITIS

Global, regional, and national age–sex specific all-cause and cause-specific mortality for 240 causes of death, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013

(2015)   LANCET

Serum hepatitis B virus RNA levels as an early predictor of hepatitis B envelope antigen seroconversion during treatment with polymerase inhibitors

(2014) Florian van Bömmel et al.   HEPATOLOGY

HBsAg quantification to optimize treatment monitoring in chronic hepatitis B patients

(2014) Michelle Martinot-Peignoux et al.   LIVER INTERNATIONAL

HBsAg seroclearance after nucleoside analogue therapy in patients with chronic hepatitis B: clinical outcomes and durability

(2013) Gi-Ae Kim et al.   GUT

Hepatocyte-targeted RNAi Therapeutics for the Treatment of Chronic Hepatitis B Virus Infection

(2013) Christine I Wooddell et al.   MOLECULAR THERAPY

The effects of hepatitis B virus integration into the genomes of hepatocellular carcinoma patients

(2012) Z. Jiang et al.   GENOME RESEARCH

Innate and adaptive immune responses in chronic hepatitis B virus infections: towards restoration of immune control of viral infection

(2011) Antonio Bertoletti et al.   GUT

Entecavir plus tenofovir combination as rescue therapy in pre-treated chronic hepatitis B patients: An international multicenter cohort study

(2011) Jorg Petersen et al.   JOURNAL OF HEPATOLOGY

A longitudinal study on the natural history of serum hepatitis B surface antigen changes in chronic hepatitis B

(2010) Henry Lik-Yuen Chan et al.   HEPATOLOGY

Serum hepatitis B surface antigen and hepatitis B e antigen titers: Disease phase influences correlation with viral load and intrahepatic hepatitis B virus markers

(2010) Alexander J.V. Thompson et al.   HEPATOLOGY

Clonal Expansion of Normal-Appearing Human Hepatocytes during Chronic Hepatitis B Virus Infection

(2010) W. S. Mason et al.   JOURNAL OF VIROLOGY

The Size of the Viral Inoculum Contributes to the Outcome of Hepatitis B Virus Infection

(2009) S. Asabe et al.   JOURNAL OF VIROLOGY

Detection of Clonally Expanded Hepatocytes in Chimpanzees with Chronic Hepatitis B Virus Infection

(2009) W. S. Mason et al.   JOURNAL OF VIROLOGY

Posttranscriptional control of HBV gene expression

(2008) Gunhild Sommer   Frontiers in Bioscience-Landmark

HBsAg Seroclearance in Chronic Hepatitis B in Asian Patients: Replicative Level and Risk of Hepatocellular Carcinoma

(2008) Man–Fung Yuen et al.   GASTROENTEROLOGY

RNA-Seq: a revolutionary tool for transcriptomics

(2008) Zhong Wang et al.   NATURE REVIEWS GENETICS