Rosiglitazone Prevents Autophagy by Regulating Nrf2-Antioxidant Response Element in a Rat Model of Lithium-pilocarpine-induced Status Epilepticus

FAM134B Attenuates Seizure-Induced Apoptosis and Endoplasmic Reticulum Stress in Hippocampal Neurons by Promoting Autophagy

(2020) Nanchang Xie et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Tsg101 positively regulates P62-Keap1-Nrf2 pathway to protect hearts against oxidative damage

(2020) Shan Deng et al.   Redox Biology

Targeting oxidative stress improves disease outcomes in a rat model of acquired epilepsy

(2019) Alberto Pauletti et al.   BRAIN

LC3-positive structures are prominent in autophagy-deficient cells

(2019) Gautam Runwal et al.   Scientific Reports

Effect of Ibuprofen on Autophagy of Astrocytes During Pentylenetetrazol-Induced Epilepsy and its Significance: An Experimental Study

(2019) Jiangtao Peng et al.   NEUROCHEMICAL RESEARCH

Combination antioxidant therapy prevents epileptogenesis and modifies chronic epilepsy

(2019) Tawfeeq Shekh-Ahmad et al.   Redox Biology

Aggravation of Cerebral Ischemia/Reperfusion Injury by Peroxisome Proliferator-Activated Receptor-Gamma Deficiency via Endoplasmic Reticulum Stress

(2019) Yueping Chen et al.   MEDICAL SCIENCE MONITOR

KEAP1 inhibition is neuroprotective and suppresses the development of epilepsy

(2018) Tawfeeq Shekh-Ahmad et al.   BRAIN

Ketogenic diet attenuates neuronal injury via autophagy and mitochondrial pathways in pentylenetetrazol-kindled seizures

(2018) Bao-Hui Wang et al.   BRAIN RESEARCH

Alterations of apoptosis and autophagy in developing brain of rats with epilepsy: Changes in LC3, P62, Beclin-1 and Bcl-2 levels

(2018) Qinrui Li et al.   NEUROSCIENCE RESEARCH

Nrf2-p62 autophagy pathway and its response to oxidative stress in hepatocellular carcinoma

(2018) Desirée Bartolini et al.   Translational Research

Voltage-Dependent Calcium Channels, Calcium Binding Proteins, and Their Interaction in the Pathological Process of Epilepsy

(2018) Jie-Hua Xu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Oxidative Stress Contributes to Status Epilepticus Associated Mortality

(2017) Jennifer N. Pearson-Smith et al.   NEUROCHEMICAL RESEARCH

Isodeoxyelephantopin induces protective autophagy in lung cancer cells via Nrf2-p62-keap1 feedback loop

(2017) Yang Wang et al.   Cell Death & Disease

miR-96 attenuates status epilepticus-induced brain injury by directly targeting Atg7 and Atg16L1

(2017) Jing Gan et al.   Scientific Reports

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

Salidroside protects against kainic acid-induced status epilepticus via suppressing oxidative stress

(2016) Pei-Pei Si et al.   NEUROSCIENCE LETTERS

Localization of PPAR isotypes in the adult mouse and human brain

(2016) Anna Warden et al.   Scientific Reports

A definition and classification of status epilepticus - Report of the ILAE Task Force on Classification of Status Epilepticus

(2015) Eugen Trinka et al.   EPILEPSIA

Neuroprotective effects of vildagliptin in rat rotenone Parkinson's disease model: role of RAGE-NFκB and Nrf2-antioxidant signaling pathways

(2015) Rania M. Abdelsalam et al.   JOURNAL OF NEUROCHEMISTRY

Impaired firing properties of dentate granule neurons in an Alzheimer's disease animal model are rescued by PPARγ agonism

(2015) Miroslav N. Nenov et al.   JOURNAL OF NEUROPHYSIOLOGY

Peroxisome proliferator-activated receptor-γ agonist inhibits the mammalian target of rapamycin signaling pathway and has a protective effect in a rat model of status epilepticus

(2015) YONG-ZHI SAN et al.   Molecular Medicine Reports

Status epilepticus results in persistent overproduction of reactive oxygen species, inhibition of which is neuroprotective

(2015) S. Williams et al.   NEUROSCIENCE

Seizure-Induced Oxidative Stress in Temporal Lobe Epilepsy

(2015) Sreekanth Puttachary et al.   Biomed Research International

p62/SQSTM1 upregulation constitutes a survival mechanism that occurs during granulocytic differentiation of acute myeloid leukemia cells

(2014) A Trocoli et al.   CELL DEATH AND DIFFERENTIATION

PPAR agonists regulate brain gene expression: Relationship to their effects on ethanol consumption

(2014) Laura B. Ferguson et al.   NEUROPHARMACOLOGY

The Role of the Selective Adaptor p62 and Ubiquitin-Like Proteins in Autophagy

(2014) Mónika Lippai et al.   Biomed Research International

Nrf2 defense pathway: Experimental evidence for its protective role in epilepsy

(2013) Manuela Mazzuferi et al.   ANNALS OF NEUROLOGY

An Overview of Autophagy: Morphology, Mechanism, and Regulation

(2013) Katherine R. Parzych et al.   ANTIOXIDANTS & REDOX SIGNALING

Activation of Nrf2-ARE signal pathway protects the brain from damage induced by epileptic seizure

(2013) Wei Wang et al.   BRAIN RESEARCH

Adipocyte reporter assays: Application for identification of anti-inflammatory and antioxidant properties of mangosteen xanthones

(2013) Qiwen Shen et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Autoimmune and inflammatory epilepsies

(2012) Rima Nabbout   EPILEPSIA

Possible involvement of PPAR-gamma receptor and nitric oxide pathway in the anticonvulsant effect of acute pioglitazone on pentylenetetrazole-induced seizures in mice

(2012) Razieh Adabi Mohazab et al.   EPILEPSY RESEARCH

Prolonged seizure activity impairs mitochondrial bioenergetics and induces cell death

(2012) S. Kovac et al.   JOURNAL OF CELL SCIENCE

PPARs are a unique set of fatty acid regulated transcription factors controlling both lipid metabolism and inflammation

(2011) Tamas Varga et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Autophagy and p62 in Cardiac Proteinopathy

(2011) Qingwen Zheng et al.   CIRCULATION RESEARCH

Anti-Inflammatory and Antioxidant Properties of a New Arylidene-Thiazolidinedione in Macrophages

(2011) L. A. Faine et al.   CURRENT MEDICINAL CHEMISTRY

Immune-mediated epilepsies

(2011) Tiziana Granata et al.   EPILEPSIA

Role of oxidative stress in epileptic seizures

(2011) Eun-Joo Shin et al.   NEUROCHEMISTRY INTERNATIONAL

The PPARγ agonist rosiglitazone prevents cognitive impairment by inhibiting astrocyte activation and oxidative stress following pilocarpine-induced status epilepticus

(2011) Sun Hong et al.   NEUROLOGICAL SCIENCES

p62/SQSTM1Is a Target Gene for Transcription Factor NRF2 and Creates a Positive Feedback Loop by Inducing Antioxidant Response Element-driven Gene Transcription

(2010) Ashish Jain et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of Autophagy by Reactive Oxygen Species (ROS): Implications for Cancer Progression and Treatment

(2008) Meghan B. Azad et al.   ANTIOXIDANTS & REDOX SIGNALING

Mechanistic and pharmacologic aspects of status epilepticus and its treatment with new antiepileptic drugs

(2008) Claude G. Wasterlain et al.   EPILEPSIA