Nrf2 defense pathway: Experimental evidence for its protective role in epilepsy

Neuroprotective and antiepileptogenic effects of combination of anti-inflammatory drugs in the immature brain

(2013) Young Se Kwon et al.   Journal of Neuroinflammation

Neuronal degeneration and gliosis time-course in the mouse hippocampal formation after pilocarpine-induced status epilepticus

(2012) André Luiz do Nascimento et al.   BRAIN RESEARCH

Ketogenic diets

(2012) Eric H. Kossoff et al.   CURRENT OPINION IN NEUROLOGY

Rapid epileptogenesis in the mouse pilocarpine model: Video-EEG, pharmacokinetic and histopathological characterization

(2012) Manuela Mazzuferi et al.   EXPERIMENTAL NEUROLOGY

Beneficial Effects of Nrf2 Overexpression in a Mouse Model of Alexander Disease

(2012) C. M. LaPash Daniels et al.   JOURNAL OF NEUROSCIENCE

Silencing microRNA-134 produces neuroprotective and prolonged seizure-suppressive effects

(2012) Eva M Jimenez-Mateos et al.   NATURE MEDICINE

Emerging roles of Nrf2 and phase II antioxidant enzymes in neuroprotection

(2012) Meijuan Zhang et al.   PROGRESS IN NEUROBIOLOGY

Neuron-restrictive silencer factor-mediated hyperpolarization-activated cyclic nucleotide gated channelopathy in experimental temporal lobe epilepsy

(2011) Shawn McClelland et al.   ANNALS OF NEUROLOGY

Adeno-Associated Virus (AAV) Vectors in the CNS

(2011) Thomas J. McCown   CURRENT GENE THERAPY

The methylation hypothesis: Do epigenetic chromatin modifications play a role in epileptogenesis?

(2011) Katja Kobow et al.   EPILEPSIA

Modern antiepileptic drug development has failed to deliver: Ways out of the current dilemma

(2011) Wolfgang Löscher et al.   EPILEPSIA

Oxidative stress in health and disease: The therapeutic potential of Nrf2 activation

(2011) Brooks M. Hybertson et al.   MOLECULAR ASPECTS OF MEDICINE

A Systems Level, Functional Genomics Analysis of Chronic Epilepsy

(2011) Kellen D. Winden et al.   PLoS One

The future of epilepsy treatment: Focus on adeno-associated virus vector gene therapy

(2010) T.J. McCown   DRUG NEWS & PERSPECTIVES

Acute oxidative stress and systemic Nrf2 activation by the ketogenic diet

(2010) Julie B. Milder et al.   NEUROBIOLOGY OF DISEASE

Global mapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChIP-Seq profiling and network analysis

(2010) Deepti Malhotra et al.   NUCLEIC ACIDS RESEARCH

Different Susceptibility to the Parkinson's Toxin MPTP in Mice Lacking the Redox Master Regulator Nrf2 or Its Target Gene Heme Oxygenase-1

(2010) Nadia G. Innamorato et al.   PLoS One

Nrf2:INrf2 (Keap1) signaling in oxidative stress

(2009) James W. Kaspar et al.   FREE RADICAL BIOLOGY AND MEDICINE

Nrf2 regulates microglial dynamics and neuroinflammation in experimental Parkinson's disease

(2009) Ana I. Rojo et al.   GLIA

Nrf2-mediated neuroprotection in the MPTP mouse model of Parkinson's disease: Critical role for the astrocyte

(2009) Pei-Chun Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Localized delivery of fibroblast growth factor-2 and brain-derived neurotrophic factor reduces spontaneous seizures in an epilepsy model

(2009) B. Paradiso et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intrahippocampal injection of a lentiviral vector expressing Nrf2 improves spatial learning in a mouse model of Alzheimer's disease

(2009) K. Kanninen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gene expression meta-analysis identifies chromosomal regions and candidate genes involved in breast cancer metastasis

(2008) Mads Thomassen et al.   BREAST CANCER RESEARCH AND TREATMENT

Nrf2 Activation in Astrocytes Protects against Neurodegeneration in Mouse Models of Familial Amyotrophic Lateral Sclerosis

(2008) M. R. Vargas et al.   JOURNAL OF NEUROSCIENCE

Artificial MicroRNAs as siRNA Shuttles: Improved Safety as Compared to shRNAs In vitro and In vivo

(2008) Ryan L Boudreau et al.   MOLECULAR THERAPY