Experimental Models to Study Autism Spectrum Disorders: hiPSCs, Rodents and Zebrafish
出版年份 2020 全文链接
标题
Experimental Models to Study Autism Spectrum Disorders: hiPSCs, Rodents and Zebrafish
作者
关键词
-
出版物
Genes
Volume 11, Issue 11, Pages 1376
出版商
MDPI AG
发表日期
2020-11-20
DOI
10.3390/genes11111376
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Generation of a Novel Rat Model of Angelman Syndrome with a Complete Ube3a Gene Deletion
- (2020) Andie Dodge et al. Autism Research
- Hyperactivity, Memory Defects, and Craniofacial Abnormalities in Zebrafish fmr1 Mutant Larvae
- (2020) Jia Hu et al. BEHAVIOR GENETICS
- Gene replacement ameliorates deficits in mouse and human models of cyclin-dependent kinase-like 5 disorder
- (2020) Yunan Gao et al. BRAIN
- De Novo ARID1B mutations cause growth delay associated with aberrant Wnt/β–catenin signaling
- (2020) Xiaomin Liu et al. HUMAN MUTATION
- Oxytocin receptor signalling modulates novelty recognition but not social preference in zebrafish
- (2020) Diogo Ribeiro et al. JOURNAL OF NEUROENDOCRINOLOGY
- Zebrafish as a model for studying ovarian development: Recent advances from targeted gene knockout studies
- (2020) Jianzhen Li et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Joining forces: the need to combine science and ethics to address problems of validity and translation in neuropsychiatry research using animal models
- (2020) Franck L. B. Meijboom et al. Philosophy Ethics and Humanities in Medicine
- Zebrafish as a tool to study schizophrenia-associated copy number variants
- (2020) Philip D. Campbell et al. Disease Models & Mechanisms
- Impaired expression of the COSMOC/MOCOS gene unit in ASD patient stem cells
- (2020) Pauline Rontani et al. MOLECULAR PSYCHIATRY
- Modeling neuronal consequences of autism-associated gene regulatory variants with human induced pluripotent stem cells
- (2020) P. Joel Ross et al. Molecular Autism
- Altered spinogenesis in iPSC-derived cortical neurons from patients with autism carrying de novo SHANK3 mutations
- (2019) Laura Gouder et al. Scientific Reports
- The autism/neuroprotection-linked ADNP/NAP regulate the excitatory glutamatergic synapse
- (2019) Shlomo Sragovich et al. Translational Psychiatry
- Family-based exome sequencing and case-control analysis implicate CEP41 as an ASD gene
- (2019) Ashok Patowary et al. Translational Psychiatry
- Scn2a haploinsufficient mice display a spectrum of phenotypes affecting anxiety, sociability, memory flexibility and ampakine CX516 rescues their hyperactivity
- (2019) Tetsuya Tatsukawa et al. Molecular Autism
- Haploinsufficiency of autism causative gene Tbr1 impairs olfactory discrimination and neuronal activation of the olfactory system in mice
- (2019) Tzyy-Nan Huang et al. Molecular Autism
- Intestinal dysmotility in a zebrafish (Danio rerio) shank3a;shank3b mutant model of autism
- (2019) David M. James et al. Molecular Autism
- Uncovering the Functional Link Between SHANK3 Deletions and Deficiency in Neurodevelopment Using iPSC-Derived Human Neurons
- (2019) Guanqun Huang et al. Frontiers in Neuroanatomy
- SHANK2 mutations associated with autism spectrum disorder cause hyperconnectivity of human neurons
- (2019) Kirill Zaslavsky et al. NATURE NEUROSCIENCE
- Phenotypic Landscape of Schizophrenia-Associated Genes Defines Candidates and Their Shared Functions
- (2019) Summer B. Thyme et al. CELL
- Single-cell genomics identifies cell type–specific molecular changes in autism
- (2019) Dmitry Velmeshev et al. SCIENCE
- Sustained correction of associative learning deficits after brief, early treatment in a rat model of Fragile X Syndrome
- (2019) Antonis Asiminas et al. Science Translational Medicine
- CNTN5-/+or EHMT2-/+human iPSC-derived neurons from individuals with autism develop hyperactive neuronal networks
- (2019) Eric Deneault et al. eLife
- Synaptic dysfunction in human neurons with autism-associated deletions in PTCHD1-AS
- (2019) P. Joel Ross et al. BIOLOGICAL PSYCHIATRY
- Direct reprogramming into interneurons: potential for brain repair
- (2019) Maria Pereira et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Single cell analysis of autism patient with bi-allelic NRXN1-alpha deletion reveals skewed fate choice in neural progenitors and impaired neuronal functionality
- (2019) Matti Lam et al. EXPERIMENTAL CELL RESEARCH
- Atypical behaviour and connectivity in SHANK3-mutant macaques
- (2019) Yang Zhou et al. NATURE
- Cyfip1 haploinsufficient rats show white matter changes, myelin thinning, abnormal oligodendrocytes and behavioural inflexibility
- (2019) Ana I. Silva et al. Nature Communications
- Inherited and De Novo Genetic Risk for Autism Impacts Shared Networks
- (2019) Elizabeth K. Ruzzo et al. CELL
- Reelin Signaling Controls the Preference for Social Novelty in Zebrafish
- (2019) Elisa Dalla Vecchia et al. Frontiers in Behavioral Neuroscience
- Use of Zebrafish in Drug Discovery Toxicology
- (2019) Steven Cassar et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Biallelic Mutations in TSC2 Lead to Abnormalities Associated with Cortical Tubers in Human iPSC-Derived Neurons
- (2019) Kellen D. Winden et al. JOURNAL OF NEUROSCIENCE
- Search-and-replace genome editing without double-strand breaks or donor DNA
- (2019) Andrew V. Anzalone et al. NATURE
- Increased Ca2+ signaling in NRXN1α+/− neurons derived from ASD induced pluripotent stem cells
- (2019) Sahar Avazzadeh et al. Molecular Autism
- Sex-dependent effects of Cacna1c haploinsufficiency on behavioral inhibition evoked by conspecific alarm signals in rats
- (2019) Markus Wöhr et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Dual Molecular Effects of Dominant RORA Mutations Cause Two Variants of Syndromic Intellectual Disability with Either Autism or Cerebellar Ataxia
- (2018) Claire Guissart et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Estimation of clinical trial success rates and related parameters
- (2018) Chi Heem Wong et al. BIOSTATISTICS
- Embryonic exposure to valproic acid affects the histaminergic system and the social behaviour of adult zebrafish (Danio rerio )
- (2018) Diego Baronio et al. BRITISH JOURNAL OF PHARMACOLOGY
- Transcriptome Engineering with RNA-Targeting Type VI-D CRISPR Effectors
- (2018) Silvana Konermann et al. CELL
- Altered Neocortical Gene Expression, Brain Overgrowth and Functional Over-Connectivity in Chd8 Haploinsufficient Mice
- (2018) Philipp Suetterlin et al. CEREBRAL CORTEX
- A Forward Genetic Screen in Zebrafish Identifies the G-Protein-Coupled Receptor CaSR as a Modulator of Sensorimotor Decision Making
- (2018) Roshan A. Jain et al. CURRENT BIOLOGY
- Dual Requirement of CHD8 for Chromatin Landscape Establishment and Histone Methyltransferase Recruitment to Promote CNS Myelination and Repair
- (2018) Chuntao Zhao et al. DEVELOPMENTAL CELL
- Progress in the genetics of autism spectrum disorder
- (2018) Marc Woodbury-Smith et al. DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY
- Cacna1c haploinsufficiency leads to pro-social 50-kHz ultrasonic communication deficits in rats
- (2018) Theresa M. Kisko et al. Disease Models & Mechanisms
- Zebrafish models of autism spectrum disorder
- (2018) Daria A. Meshalkina et al. EXPERIMENTAL NEUROLOGY
- Rare RELN variants affect Reelin-DAB1 signal transduction in autism spectrum disorder
- (2018) Sandra M. Sánchez-Sánchez et al. HUMAN MUTATION
- Altered TAOK2 activity causes autism-related neurodevelopmental and cognitive abnormalities through RhoA signaling
- (2018) Melanie Richter et al. MOLECULAR PSYCHIATRY
- Purkinje cells derived from TSC patients display hypoexcitability and synaptic deficits associated with reduced FMRP levels and reversed by rapamycin
- (2018) Maria Sundberg et al. MOLECULAR PSYCHIATRY
- p53 inhibits CRISPR–Cas9 engineering in human pluripotent stem cells
- (2018) Robert J. Ihry et al. NATURE MEDICINE
- CRISPR–Cas9 genome editing induces a p53-mediated DNA damage response
- (2018) Emma Haapaniemi et al. NATURE MEDICINE
- Intermittent fasting uncovers and rescues cognitive phenotypes in PTEN neuronal haploinsufficient mice
- (2018) J. V. Cabral-Costa et al. Scientific Reports
- CRISPR/Cas9-induced shank3b mutant zebrafish display autism-like behaviors
- (2018) Chun-xue Liu et al. Molecular Autism
- Single-cell trajectory analysis of human homogenous neurons carrying a rare RELN variant
- (2018) Yuko Arioka et al. Translational Psychiatry
- Hyperactivity and Hypermotivation Associated With Increased Striatal mGluR1 Signaling in a Shank2 Rat Model of Autism
- (2018) Meera E. Modi et al. Frontiers in Molecular Neuroscience
- Altered auditory processing, filtering, and reactivity in theCntnap2knockout rat model for neurodevelopmental disorders
- (2018) Kaela E. Scott et al. JOURNAL OF NEUROSCIENCE
- Evolved Cas9 variants with broad PAM compatibility and high DNA specificity
- (2018) Johnny H. Hu et al. NATURE
- Sexually dimorphic behavior, neuronal activity, and gene expression in Chd8-mutant mice
- (2018) Hwajin Jung et al. NATURE NEUROSCIENCE
- Plausibility of the zebrafish embryos/larvae as an alternative animal model for autism: A comparison study of transcriptome changes
- (2018) Sangwoo Lee et al. PLoS One
- Zebrafish Models of Neurodevelopmental Disorders: Past, Present, and Future
- (2018) Catalina Sakai et al. Frontiers in Molecular Neuroscience
- De novo Mutations (DNMs) in Autism Spectrum Disorder (ASD): Pathway and Network Analysis
- (2018) Aitana Alonso-Gonzalez et al. Frontiers in Genetics
- Early Correction of N-Methyl-D-Aspartate Receptor Function Improves Autistic-like Social Behaviors in Adult Shank2−/− Mice
- (2018) Changuk Chung et al. BIOLOGICAL PSYCHIATRY
- Chd2 Is Necessary for Neural Circuit Development and Long-Term Memory
- (2018) Young J. Kim et al. NEURON
- Neonatal Tbr1 Dosage Controls Cortical Layer 6 Connectivity
- (2018) Siavash Fazel Darbandi et al. NEURON
- Convergent microstructural brain changes across genetic models of autism spectrum disorder—A pilot study
- (2018) Paul A. Rowley et al. PSYCHIATRY RESEARCH-NEUROIMAGING
- Larval zebrafish model for studying the effects of valproic acid on neurodevelopment: An approach towards modeling autism
- (2018) Shubham Dwivedi et al. JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS
- Developmental protein kinase C hyper-activation results in microcephaly and behavioral abnormalities in zebrafish
- (2018) Taian Liu et al. Translational Psychiatry
- Complete Disruption of Autism-Susceptibility Genes by Gene Editing Predominantly Reduces Functional Connectivity of Isogenic Human Neurons
- (2018) Eric Deneault et al. Stem Cell Reports
- Arid1b Haploinsufficiency Causes Abnormal Brain Gene Expression and Autism-Related Behaviors in Mice
- (2017) Mihiro Shibutani et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- What Is the Male-to-Female Ratio in Autism Spectrum Disorder? A Systematic Review and Meta-Analysis
- (2017) Rachel Loomes et al. JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY
- Adult zebrafish in CNS disease modeling: a tank that's half-full, not half-empty, and still filling
- (2017) Darya A Meshalkina et al. LAB ANIMAL
- PREPARE: guidelines for planning animal research and testing
- (2017) Adrian J Smith et al. LABORATORY ANIMALS
- A Upf3b-mutant mouse model with behavioral and neurogenesis defects
- (2017) L Huang et al. MOLECULAR PSYCHIATRY
- Stem cell-derived neurons from autistic individuals with SHANK3 mutation show morphogenetic abnormalities during early development
- (2017) A Kathuria et al. MOLECULAR PSYCHIATRY
- RNA targeting with CRISPR–Cas13
- (2017) Omar O. Abudayyeh et al. NATURE
- Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage
- (2017) Nicole M. Gaudelli et al. NATURE
- Disruption of the ATXN1–CIC complex causes a spectrum of neurobehavioral phenotypes in mice and humans
- (2017) Hsiang-Chih Lu et al. NATURE GENETICS
- Germline Chd8 haploinsufficiency alters brain development in mouse
- (2017) Andrea L Gompers et al. NATURE NEUROSCIENCE
- Linking Neurons to Network Function and Behavior by Two-Photon Holographic Optogenetics and Volumetric Imaging
- (2017) Marco dal Maschio et al. NEURON
- Enhancing inhibitory synaptic function reverses spatial memory deficits in Shank2 mutant mice
- (2017) Chae-Seok Lim et al. NEUROPHARMACOLOGY
- Generation and characterization of Kctd15 mutations in zebrafish
- (2017) Alison Heffer et al. PLoS One
- Sex-specific gene–environment interactions underlying ASD-like behaviors
- (2017) Sara M. Schaafsma et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Modulation of prefrontal cortex excitation/inhibition balance rescues social behavior in CNTNAP2 -deficient mice
- (2017) Aslihan Selimbeyoglu et al. Science Translational Medicine
- Sleep/Wake Physiology and Quantitative Electroencephalogram Analysis of the Neuroligin-3 Knockout Rat Model of Autism Spectrum Disorder
- (2017) Alexia M Thomas et al. SLEEP
- Fragile X Mental Retardation-1 Knockout Zebrafish Shows Precocious Development in Social Behavior
- (2017) Yao-Ju Wu et al. Zebrafish
- Chd8 Mutation Leads to Autistic-like Behaviors and Impaired Striatal Circuits
- (2017) Randall J. Platt et al. Cell Reports
- Guidelines for morpholino use in zebrafish
- (2017) Didier Y. R. Stainier et al. PLoS Genetics
- MYT1L mutations cause intellectual disability and variable obesity by dysregulating gene expression and development of the neuroendocrine hypothalamus
- (2017) Patricia Blanchet et al. PLoS Genetics
- Oxytocin improves behavioral and electrophysiological deficits in a novel Shank3-deficient rat
- (2017) Hala Harony-Nicolas et al. eLife
- Arid1b haploinsufficient mice reveal neuropsychiatric phenotypes and reversible causes of growth impairment
- (2017) Cemre Celen et al. eLife
- CRISPR/Cas9-mediated heterozygous knockout of the autism gene CHD8 and characterization of its transcriptional networks in cerebral organoids derived from iPS cells
- (2017) Ping Wang et al. Molecular Autism
- Zebrafish knockout of Down syndrome gene, DYRK1A, shows social impairments relevant to autism
- (2017) Oc-Hee Kim et al. Molecular Autism
- Environmental risk factors for autism: an evidence-based review of systematic reviews and meta-analyses
- (2017) Amirhossein Modabbernia et al. Molecular Autism
- Altered neurite morphology and cholinergic function of induced pluripotent stem cell-derived neurons from a patient with Kleefstra syndrome and autism
- (2017) J Nagy et al. Translational Psychiatry
- Editorial: Autism Spectrum Disorders: Developmental Trajectories, Neurobiological Basis, Treatment Update
- (2017) Roberto Canitano et al. Frontiers in Psychiatry
- Sleep/Wake Physiology and Quantitative Electroencephalogram Analysis of the Neuroligin-3 Knockout Rat Model of Autism Spectrum Disorder
- (2017) Alexia M Thomas et al. SLEEP
- Peripheral Mechanosensory Neuron Dysfunction Underlies Tactile and Behavioral Deficits in Mouse Models of ASDs
- (2016) Lauren L. Orefice et al. CELL
- Biology and Applications of CRISPR Systems: Harnessing Nature’s Toolbox for Genome Engineering
- (2016) Addison V. Wright et al. CELL
- Rodent models in neuroscience research: is it a rat race?
- (2016) Bart Ellenbroek et al. Disease Models & Mechanisms
- Characterization of Rett Syndrome-like phenotypes in Mecp2-knockout rats
- (2016) Yang Wu et al. Journal of Neurodevelopmental Disorders
- QRFP and Its Receptors Regulate Locomotor Activity and Sleep in Zebrafish
- (2016) A. Chen et al. JOURNAL OF NEUROSCIENCE
- Cerebellar Shank2 Regulates Excitatory Synapse Density, Motor Coordination, and Specific Repetitive and Anxiety-Like Behaviors
- (2016) S. Ha et al. JOURNAL OF NEUROSCIENCE
- Sexual divergence in microtubule function: the novel intranasal microtubule targeting SKIP normalizes axonal transport and enhances memory
- (2016) N Amram et al. MOLECULAR PSYCHIATRY
- CHD8 haploinsufficiency results in autistic-like phenotypes in mice
- (2016) Yuta Katayama et al. NATURE
- Chd8 mediates cortical neurogenesis via transcriptional regulation of cell cycle and Wnt signaling
- (2016) Omer Durak et al. NATURE NEUROSCIENCE
- Induced pluripotent stem cell technology: a decade of progress
- (2016) Yanhong Shi et al. NATURE REVIEWS DRUG DISCOVERY
- Estrogens Suppress a Behavioral Phenotype in Zebrafish Mutants of the Autism Risk Gene, CNTNAP2
- (2016) Ellen J. Hoffman et al. NEURON
- Alternative Animal and Non-Animal Models for Drug Discovery and Development: Bonus or Burden?
- (2016) Irlan Almeida Freires et al. PHARMACEUTICAL RESEARCH
- A Spontaneous Missense Mutation in Branched Chain Keto Acid Dehydrogenase Kinase in the Rat Affects Both the Central and Peripheral Nervous Systems
- (2016) J. Samuel Zigler et al. PLoS One
- Cntnap2 Knockout Rats and Mice Exhibit Epileptiform Activity and Abnormal Sleep–Wake Physiology
- (2016) Alexia M. Thomas et al. SLEEP
- On the Origin of CRISPR-Cas Technology: From Prokaryotes to Mammals
- (2016) Francisco J.M. Mojica et al. TRENDS IN MICROBIOLOGY
- Histone methyltransferase Ash1L mediates activity-dependent repression of neurexin-1α
- (2016) Τao Zhu et al. Scientific Reports
- Impaired Mitochondrial Dynamics and Mitophagy in Neuronal Models of Tuberous Sclerosis Complex
- (2016) Darius Ebrahimi-Fakhari et al. Cell Reports
- Human Pluripotent Stem Cell-derived Cortical Neurons for High Throughput Medication Screening in Autism: A Proof of Concept Study in SHANK3 Haploinsufficiency Syndrome
- (2016) Hélène Darville et al. EBioMedicine
- Cntnap2 Knockout Rats and Mice Exhibit Epileptiform Activity and Abnormal Sleep–Wake Physiology
- (2016) Alexia M. Thomas et al. SLEEP
- Transcriptional enhancement of Smn levels in motoneurons is crucial for proper axon morphology in zebrafish
- (2016) Zoltán Spiró et al. Scientific Reports
- Gain-of-function defects of astrocytic Kir4.1 channels in children with autism spectrum disorders and epilepsy
- (2016) Federico Sicca et al. Scientific Reports
- Phenotypic characterization of nonsocial behavioral impairment in neurexin 1α knockout rats.
- (2015) Frederic Esclassan et al. BEHAVIORAL NEUROSCIENCE
- The Histone Methyltransferase Gene Absent, Small, or Homeotic Discs-1 Like Is Required for Normal Hox Gene Expression and Fertility in Mice1
- (2015) Michelle L. Brinkmeier et al. BIOLOGY OF REPRODUCTION
- Necessary Conditions for Morally Responsible Animal Research
- (2015) DAVID DeGRAZIA et al. CAMBRIDGE QUARTERLY OF HEALTHCARE ETHICS
- Neurobeachin Is Required Postsynaptically for Electrical and Chemical Synapse Formation
- (2015) Adam C. Miller et al. CURRENT BIOLOGY
- Collybistin binds and inhibits mTORC1 signaling: a potential novel mechanism contributing to intellectual disability and autism
- (2015) Camila Oliveira Freitas Machado et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Decreased aggression and increased repetitive behavior inPtenhaploinsufficient mice
- (2015) A. E. Clipperton-Allen et al. GENES BRAIN AND BEHAVIOR
- Copy number variants in patients with intellectual disability affect the regulation of ARX transcription factor gene
- (2015) Minaka Ishibashi et al. HUMAN GENETICS
- Two knockdown models of the autism genes SYNGAP1 and SHANK3 in zebrafish produce similar behavioral phenotypes associated with embryonic disruptions of brain morphogenesis
- (2015) Robert A. Kozol et al. HUMAN MOLECULAR GENETICS
- Kabuki syndrome genesKMT2DandKDM6A: functional analyses demonstrate critical roles in craniofacial, heart and brain development
- (2015) Peter M. Van Laarhoven et al. HUMAN MOLECULAR GENETICS
- RAP1-mediated MEK/ERK pathway defects in Kabuki syndrome
- (2015) Nina Bögershausen et al. JOURNAL OF CLINICAL INVESTIGATION
- Hyperactivity of Newborn Pten Knock-out Neurons Results from Increased Excitatory Synaptic Drive
- (2015) M. R. Williams et al. JOURNAL OF NEUROSCIENCE
- Altered neuronal network and rescue in a human MECP2 duplication model
- (2015) S Nageshappa et al. MOLECULAR PSYCHIATRY
- Genetic and functional analyses demonstrate a role for abnormal glycinergic signaling in autism
- (2015) M Pilorge et al. MOLECULAR PSYCHIATRY
- Loss of δ-catenin function in severe autism
- (2015) Tychele N. Turner et al. NATURE
- CRISPRscan: designing highly efficient sgRNAs for CRISPR-Cas9 targeting in vivo
- (2015) Miguel A Moreno-Mateos et al. NATURE METHODS
- Degraded neural and behavioral processing of speech sounds in a rat model of Rett syndrome
- (2015) Crystal T. Engineer et al. NEUROBIOLOGY OF DISEASE
- Restoration of Normal Cerebral Oxygen Consumption with Rapamycin Treatment in a Rat Model of Autism–Tuberous Sclerosis
- (2015) Oak Z. Chi et al. NEUROMOLECULAR MEDICINE
- Autistic-Like Traits and Cerebellar Dysfunction in Purkinje Cell PTEN Knock-Out Mice
- (2015) Dario Cupolillo et al. NEUROPSYCHOPHARMACOLOGY
- Abnormal neuronal morphology and neurochemistry in the auditory brainstem of Fmr1 knockout rats
- (2015) K. Ruby et al. NEUROSCIENCE
- Prenatal factors associated with autism spectrum disorder (ASD)
- (2015) A. Ornoy et al. REPRODUCTIVE TOXICOLOGY
- A prudent path forward for genomic engineering and germline gene modification
- (2015) D. Baltimore et al. SCIENCE
- Rationally engineered Cas9 nucleases with improved specificity
- (2015) I. M. Slaymaker et al. SCIENCE
- Exogenous and evoked oxytocin restores social behavior in the Cntnap2 mouse model of autism
- (2015) Olga Peñagarikano et al. Science Translational Medicine
- Methyl-CpG Binding Protein 2 (Mecp2) Regulates Sensory Function Through Sema5b and Robo2
- (2015) Wan Y. Leong et al. Frontiers in Cellular Neuroscience
- Trans-synaptic zinc mobilization improves social interaction in two mouse models of autism through NMDAR activation
- (2015) Eun-Jae Lee et al. Nature Communications
- The Parvalbumin/Somatostatin Ratio Is Increased in Pten Mutant Mice and by Human PTEN ASD Alleles
- (2015) Daniel Vogt et al. Cell Reports
- Advancing biology through a deeper understanding of zebrafish ecology and evolution
- (2015) David M Parichy eLife
- CRISPR/Cas9-mediated heterozygous knockout of the autism gene CHD8 and characterization of its transcriptional networks in neurodevelopment
- (2015) Ping Wang et al. Molecular Autism
- ZNF804A Transcriptional Networks in Differentiating Neurons Derived from Induced Pluripotent Stem Cells of Human Origin
- (2015) Jian Chen et al. PLoS One
- Fmr1 and Nlgn3 knockout rats: Novel tools for investigating autism spectrum disorders.
- (2014) Shannon M. Hamilton et al. BEHAVIORAL NEUROSCIENCE
- Development and Applications of CRISPR-Cas9 for Genome Engineering
- (2014) Patrick D. Hsu et al. CELL
- Disruptive CHD8 Mutations Define a Subtype of Autism Early in Development
- (2014) Raphael Bernier et al. CELL
- Whole-Genome Sequencing Analysis Reveals High Specificity of CRISPR/Cas9 and TALEN-Based Genome Editing in Human iPSCs
- (2014) Cory Smith et al. Cell Stem Cell
- Methylphenidate improves learning impairments and hyperthermia-induced seizures caused by anScn1amutation
- (2014) Iori Ohmori et al. EPILEPSIA
- In vivo detection of reduced Purkinje cell fibers with diffusion MRI tractography in children with autistic spectrum disorders
- (2014) Jeong-Won Jeong et al. Frontiers in Human Neuroscience
- Modeling non-syndromic autism and the impact of TRPC6 disruption in human neurons
- (2014) K Griesi-Oliveira et al. MOLECULAR PSYCHIATRY
- The contribution of de novo coding mutations to autism spectrum disorder
- (2014) Ivan Iossifov et al. NATURE
- Tbr1 haploinsufficiency impairs amygdalar axonal projections and results in cognitive abnormality
- (2014) Tzyy-Nan Huang et al. NATURE NEUROSCIENCE
- CHD8regulates neurodevelopmental pathways associated with autism spectrum disorder in neural progenitors
- (2014) Aarathi Sugathan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Anxiety, hyperactivity and stereotypy in a zebrafish model of fragile X syndrome and autism spectrum disorder
- (2014) Lily Kim et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Zebrafish models of human motor neuron diseases: Advantages and limitations
- (2014) Patrick J. Babin et al. PROGRESS IN NEUROBIOLOGY
- The new frontier of genome engineering with CRISPR-Cas9
- (2014) J. A. Doudna et al. SCIENCE
- iPSC-Derived Forebrain Neurons from FXS Individuals Show Defects in Initial Neurite Outgrowth
- (2014) Matthew E. Doers et al. STEM CELLS AND DEVELOPMENT
- Induction of Social Behavior in Zebrafish: Live Versus Computer Animated Fish as Stimuli
- (2014) Meiying Qin et al. Zebrafish
- Alteration in basal and depolarization induced transcriptional network in iPSC derived neurons from Timothy syndrome
- (2014) Yuan Tian et al. Genome Medicine
- Involvement of Synaptic Genes in the Pathogenesis of Autism Spectrum Disorders: The Case of Synapsins
- (2014) Silvia Giovedà et al. Frontiers in Pediatrics
- De Novo Loss-of-Function Mutations in CHD2 Cause a Fever-Sensitive Myoclonic Epileptic Encephalopathy Sharing Features with Dravet Syndrome
- (2013) Arvid Suls et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Decreased Reelin Expression and Organophosphate Pesticide Exposure Alters Mouse Behaviour and Brain Morphology
- (2013) Brian R. Mullen et al. ASN Neuro
- Behavioural methods used in rodent models of autism spectrum disorders: Current standards and new developments
- (2013) Markus Wöhr et al. BEHAVIOURAL BRAIN RESEARCH
- Maturation of shoaling in two zebrafish strains: A behavioral and neurochemical analysis
- (2013) Samantha Mahabir et al. BEHAVIOURAL BRAIN RESEARCH
- New approach for fish breeding by chemical mutagenesis: establishment of TILLING method in fugu (Takifugu rubripes) with ENU mutagenesis
- (2013) Miwa Kuroyanagi et al. BMC GENOMICS
- Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression
- (2013) Lei S. Qi et al. CELL
- Defining the Role of Cerebellar Purkinje Cells in Autism Spectrum Disorders
- (2013) Anamaria Sudarov CEREBELLUM
- Cloacal exstrophy with extensive Chiari II malformation: case report and review of the literature
- (2013) Obed M. Nyarenchi et al. CHILDS NERVOUS SYSTEM
- Transgenic tools to characterize neuronal properties of discrete populations of zebrafish neurons
- (2013) C. Satou et al. DEVELOPMENT
- Genome editing using artificial site-specific nucleases in zebrafish
- (2013) Yu Hisano et al. DEVELOPMENT GROWTH & DIFFERENTIATION
- Pharmacotherapy for the Core Symptoms in Autistic Disorder: Current Status of the Research
- (2013) Cristan Farmer et al. DRUGS
- Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases
- (2013) S. W. Cho et al. GENOME RESEARCH
- Histone Methyltransferase Ash1l Suppresses Interleukin-6 Production and Inflammatory Autoimmune Diseases by Inducing the Ubiquitin-Editing Enzyme A20
- (2013) Meng Xia et al. IMMUNITY
- Calcium influx through L-type CaV1.2 Ca2+ channels regulates mandibular development
- (2013) Kapil V. Ramachandran et al. JOURNAL OF CLINICAL INVESTIGATION
- Modeling Transformations of Neurodevelopmental Sequences across Mammalian Species
- (2013) A. D. Workman et al. JOURNAL OF NEUROSCIENCE
- SHANK3 and IGF1 restore synaptic deficits in neurons from 22q13 deletion syndrome patients
- (2013) Aleksandr Shcheglovitov et al. NATURE
- The zebrafish reference genome sequence and its relationship to the human genome
- (2013) Kerstin Howe et al. NATURE
- Efficient genome editing in zebrafish using a CRISPR-Cas system
- (2013) Woong Y Hwang et al. NATURE BIOTECHNOLOGY
- Heritable gene targeting in the mouse and rat using a CRISPR-Cas system
- (2013) Dali Li et al. NATURE BIOTECHNOLOGY
- Whole-brain functional imaging at cellular resolution using light-sheet microscopy
- (2013) Misha B Ahrens et al. NATURE METHODS
- RNA-guided gene activation by CRISPR-Cas9–based transcription factors
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- (2013) Christine Kohl et al. PLoS One
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- (2013) William H. J. Norton Frontiers in Neural Circuits
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- (2013) Andrew R. Bassett et al. Cell Reports
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- (2013) Martin Jinek et al. eLife
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- (2013) Brett S Abrahams et al. Molecular Autism
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- (2013) A P Mullin et al. Translational Psychiatry
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- (2013) C Boissart et al. Translational Psychiatry
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- (2012) Ksenia Z. Meyza et al. BEHAVIOURAL BRAIN RESEARCH
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- (2012) Ajay S. Mathuru et al. CURRENT BIOLOGY
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- (2012) Sean E. Low et al. JOURNAL OF NEUROPHYSIOLOGY
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- (2012) A. Valente et al. LEARNING & MEMORY
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- (2012) K J Brennand et al. MOLECULAR PSYCHIATRY
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- (2011) Thomas Mueller et al. BRAIN RESEARCH
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- (2011) Olga Peñagarikano et al. CELL
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- (2011) Yanwei Xi et al. DEVELOPMENTAL DYNAMICS
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- (2011) Steven D. Sheridan et al. PLoS One
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- (2011) Bruno Rezende Souza et al. REVIEWS IN THE NEUROSCIENCES
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- (2011) Daniel H. Geschwind TRENDS IN COGNITIVE SCIENCES
- Somatosensory and sensorimotor consequences associated with the heterozygous disruption of the autism candidate gene, Gabrb3
- (2010) Timothy M. DeLorey et al. BEHAVIOURAL BRAIN RESEARCH
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- (2010) Shuichi Kani et al. DEVELOPMENTAL BIOLOGY
- Targeted Genome Modification in Mice Using Zinc-Finger Nucleases
- (2010) I. D. Carbery et al. GENETICS
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- (2010) M. Christian et al. GENETICS
- Organization of Myelinated Axons by Caspr and Caspr2 Requires the Cytoskeletal Adapter Protein 4.1B
- (2010) I. Horresh et al. JOURNAL OF NEUROSCIENCE
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- (2010) Jill L. Silverman et al. NATURE REVIEWS NEUROSCIENCE
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- (2010) Pablo Huertas NATURE STRUCTURAL & MOLECULAR BIOLOGY
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- (2010) Nicole A. Hawkins et al. NEUROBIOLOGY OF DISEASE
- Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research
- (2010) Carol Kilkenny et al. PLOS BIOLOGY
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- (2009) Rebecca E. Rosenberg et al. ARCHIVES OF PEDIATRICS & ADOLESCENT MEDICINE
- An Evolutionary Interpretation of Teleostean Forebrain Anatomy
- (2009) Thomas Mueller et al. BRAIN BEHAVIOR AND EVOLUTION
- The autism susceptibility gene met regulates zebrafish cerebellar development and facial motor neuron migration
- (2009) Gina E. Elsen et al. DEVELOPMENTAL BIOLOGY
- Anatomy of zebrafish cerebellum and screen for mutations affecting its development
- (2009) Young-Ki Bae et al. DEVELOPMENTAL BIOLOGY
- Using zebrafish to assess the impact of drugs on neural development and function
- (2009) Su Guo Expert Opinion on Drug Discovery
- Pharmacological Inhibition of mTORC1 Suppresses Anatomical, Cellular, and Behavioral Abnormalities in Neural-Specific Pten Knock-Out Mice
- (2009) J. Zhou et al. JOURNAL OF NEUROSCIENCE
- Environmental risk factors for autism: Do they help cause de novo genetic mutations that contribute to the disorder?
- (2009) Dennis K. Kinney et al. MEDICAL HYPOTHESES
- Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases
- (2009) Dirk Hockemeyer et al. NATURE BIOTECHNOLOGY
- CHD8 suppresses p53-mediated apoptosis through histone H1 recruitment during early embryogenesis
- (2009) Masaaki Nishiyama et al. NATURE CELL BIOLOGY
- Role of chromodomain helicase DNA-binding protein 2 in DNA damage response signaling and tumorigenesis
- (2009) P Nagarajan et al. ONCOGENE
- The transmembrane inner ear (Tmie) protein is essential for normal hearing and balance in the zebrafish
- (2009) Michelle R. Gleason et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2009) Brent R. Bill et al. Zebrafish
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- (2008) J. S. Eisen et al. DEVELOPMENT
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- (2008) Christina Lillesaar et al. JOURNAL OF COMPARATIVE NEUROLOGY
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- (2008) N. Obholzer et al. JOURNAL OF NEUROSCIENCE
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- (2008) Yannick Doyon et al. NATURE BIOTECHNOLOGY
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- (2007) Natasha Speedie et al. BEHAVIOURAL BRAIN RESEARCH
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- (2007) Lu Wen et al. DEVELOPMENTAL BIOLOGY
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