标题
Toll-like receptor signalling in B cells during systemic lupus erythematosus
作者
关键词
-
出版物
Nature Reviews Rheumatology
Volume -, Issue -, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2020-12-18
DOI
10.1038/s41584-020-00544-4
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Distinct Effector B Cells Induced by Unregulated Toll-like Receptor 7 Contribute to Pathogenic Responses in Systemic Lupus Erythematosus
- (2020) Scott A. Jenks et al. IMMUNITY
- Type II but Not Type I IFN Signaling Is Indispensable for TLR7-Promoted Development of Autoreactive B Cells and Systemic Autoimmunity
- (2020) Sathi Babu Chodisetti et al. JOURNAL OF IMMUNOLOGY
- Anti-CD20–mediated B-cell depletion in autoimmune diseases: successes, failures and future perspectives
- (2020) Etienne Crickx et al. KIDNEY INTERNATIONAL
- Mechanisms of action of hydroxychloroquine and chloroquine: implications for rheumatology
- (2020) Eva Schrezenmeier et al. Nature Reviews Rheumatology
- A Missense Variant Affecting the C-Terminal Tail of UNC93B1 in Dogs with Exfoliative Cutaneous Lupus Erythematosus (ECLE)
- (2020) Tosso Leeb et al. Genes
- Investigational IRAK-4 inhibitors for the treatment of rheumatoid arthritis
- (2020) Michael D. Wiese et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- B cell–intrinsic TLR9 expression is protective in murine lupus
- (2020) Jeremy S. Tilstra et al. JOURNAL OF CLINICAL INVESTIGATION
- A Phase 2a, Double-Blind, Placebo-Controlled Randomized Trial of Inhaled TLR9 Agonist AZD1419 in Asthma
- (2020) Ioannis Psallidas et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Extrafollicular B cell responses correlate with neutralizing antibodies and morbidity in COVID-19
- (2020) Matthew C. Woodruff et al. NATURE IMMUNOLOGY
- Extrafollicular responses in humans and SLE
- (2019) Scott A. Jenks et al. IMMUNOLOGICAL REVIEWS
- IFNγ induces epigenetic programming of human T-bethi B cells and promotesTLR7/8 and IL-21 induced differentiation
- (2019) Esther Zumaquero et al. eLife
- Novel paradigms in systemic lupus erythematosus
- (2019) Thomas Dörner et al. LANCET
- Targeting IRAK4 disrupts inflammatory pathways and delays tumor development in chronic lymphocytic leukemia
- (2019) Neus Giménez et al. LEUKEMIA
- Long‐term clinical outcomes of imiquimod 5% cream vs. diclofenac 3% gel for actinic keratosis on the face or scalp: a pooled analysis of two randomized controlled trials
- (2019) H. Gollnick et al. JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
- UNC93B1 recruits syntenin-1 to dampen TLR7 signalling and prevent autoimmunity
- (2019) Olivia Majer et al. NATURE
- Identification and Characterization of Post-activated B Cells in Systemic Autoimmune Diseases
- (2019) Sarah Y. Weißenberg et al. Frontiers in Immunology
- Lupus Autoimmunity and Metabolic Parameters Are Exacerbated Upon High Fat Diet-Induced Obesity Due to TLR7 Signaling
- (2019) Noël Hanna Kazazian et al. Frontiers in Immunology
- Toll-Like Receptors and Relevant Emerging Therapeutics with Reference to Delivery Methods
- (2019) Javaid et al. Pharmaceutics
- Identification of U11snRNA as an endogenous agonist of TLR7-mediated immune pathogenesis
- (2019) Hideo Negishi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A highly selective inhibitor of interleukin-1 receptor–associated kinases 1/4 (IRAK-1/4) delineates the distinct signaling roles of IRAK-1/4 and the TAK1 kinase
- (2019) Scott A. Scarneo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Properties of FDA-approved small molecule protein kinase inhibitors: A 2020 update
- (2019) Robert Roskoski PHARMACOLOGICAL RESEARCH
- Failure of B Cell Tolerance in CVID
- (2019) Christopher T. Richardson et al. Frontiers in Immunology
- The 2018 pipeline of targeted therapies under clinical development for Systemic Lupus Erythematosus: a systematic review of trials
- (2018) Renaud Felten et al. AUTOIMMUNITY REVIEWS
- Hydroxychloroquine efficiently suppresses inflammatory responses of human class-switched memory B cells via Toll-like receptor 9 inhibition
- (2018) Masataka Torigoe et al. CLINICAL IMMUNOLOGY
- LAG-3 Inhibitory Receptor Expression Identifies Immunosuppressive Natural Regulatory Plasma Cells
- (2018) Andreia C. Lino et al. IMMUNITY
- Commensal orthologs of the human autoantigen Ro60 as triggers of autoimmunity in lupus
- (2018) Teri M. Greiling et al. Science Translational Medicine
- IL-21 drives expansion and plasma cell differentiation of autoreactive CD11chiT-bet+ B cells in SLE
- (2018) Shu Wang et al. Nature Communications
- Targeting Toll-Like Receptors for Cancer Therapy
- (2018) Marc J. Braunstein et al. Targeted Oncology
- The Role of Toll-Like Receptor in Inflammation and Tumor Immunity
- (2018) Xiaohong Cen et al. Frontiers in Pharmacology
- Distinct Effector B Cells Induced by Unregulated Toll-like Receptor 7 Contribute to Pathogenic Responses in Systemic Lupus Erythematosus
- (2018) Scott A. Jenks et al. IMMUNITY
- B cell–derived IL-6 initiates spontaneous germinal center formation during systemic autoimmunity
- (2017) Tanvi Arkatkar et al. JOURNAL OF EXPERIMENTAL MEDICINE
- TLR4 signals in B lymphocytes are transduced via the B cell antigen receptor and SYK
- (2017) Edina Schweighoffer et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Self-reactive VH4-34–expressing IgG B cells recognize commensal bacteria
- (2017) Jean-Nicolas Schickel et al. JOURNAL OF EXPERIMENTAL MEDICINE
- High SYK Expression Drives Constitutive Activation of CD21lowB Cells
- (2017) Baerbel Keller et al. JOURNAL OF IMMUNOLOGY
- Altered type II interferon precedes autoantibody accrual and elevated type I interferon activity prior to systemic lupus erythematosus classification
- (2016) Melissa E Munroe et al. ANNALS OF THE RHEUMATIC DISEASES
- Dysregulation of innate and adaptive serum mediators precedes systemic lupus erythematosus classification and improves prognostic accuracy of autoantibodies
- (2016) Rufei Lu et al. JOURNAL OF AUTOIMMUNITY
- B cell IFN-γ receptor signaling promotes autoimmune germinal centers via cell-intrinsic induction of BCL-6
- (2016) Shaun W. Jackson et al. JOURNAL OF EXPERIMENTAL MEDICINE
- IFN-γ receptor and STAT1 signaling in B cells are central to spontaneous germinal center formation and autoimmunity
- (2016) Phillip P. Domeier et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Selective IRAK4 Inhibition Attenuates Disease in Murine Lupus Models and Demonstrates Steroid Sparing Activity
- (2016) Shailesh Dudhgaonkar et al. JOURNAL OF IMMUNOLOGY
- Effect of Hydroxychloroquine Treatment on Dry Eyes in Subjects with Primary Sjögren's Syndrome: a Double-Blind Randomized Control Study
- (2016) Chang Ho Yoon et al. JOURNAL OF KOREAN MEDICAL SCIENCE
- Discovery of 6-Amino-2-{[(1S)-1-methylbutyl]oxy}-9-[5-(1-piperidinyl)pentyl]-7,9-dihydro-8H-purin-8-one (GSK2245035), a Highly Potent and Selective Intranasal Toll-Like Receptor 7 Agonist for the Treatment of Asthma
- (2016) Keith Biggadike et al. JOURNAL OF MEDICINAL CHEMISTRY
- Association between toll-like receptor polymorphisms and systemic lupus erythematosus: a meta-analysis update
- (2016) Y H Lee et al. LUPUS
- CYT003, a TLR9 agonist, in persistent allergic asthma - a randomized placebo-controlled Phase 2b study
- (2015) T. B. Casale et al. ALLERGY
- Early clinical evaluation of the intranasal TLR7 agonist GSK2245035: Use of translational biomarkers to guide dosing and confirm target engagement
- (2015) D Tsitoura et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- The role of serum IL-17 and IL-6 as biomarkers of disease activity and predictors of remission in patients with lupus nephritis
- (2015) Sahar M. Abdel Galil et al. CYTOKINE
- Toll-like receptor 8 deletion accelerates autoimmunity in a mouse model of lupus through a Toll-like receptor 7-dependent mechanism
- (2015) Ngoc Lan Tran et al. IMMUNOLOGY
- Associations of toll-like receptor (TLR)-4 single nucleotide polymorphisms and rheumatoid arthritis disease progression: An observational cohort study
- (2015) Marshall L.R. Davis et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Selective interleukin-1 receptor–associated kinase 4 inhibitors for the treatment of autoimmune disorders and lymphoid malignancy
- (2015) Priscilla N. Kelly et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Syk Tyrosine Kinase Is Critical for B Cell Antibody Responses and Memory B Cell Survival
- (2015) Jochen A. Ackermann et al. JOURNAL OF IMMUNOLOGY
- Cell-Intrinsic Expression of TLR9 in Autoreactive B Cells Constrains BCR/TLR7-Dependent Responses
- (2015) Kerstin Nündel et al. JOURNAL OF IMMUNOLOGY
- Diversity, cellular origin and autoreactivity of antibody-secreting cell population expansions in acute systemic lupus erythematosus
- (2015) Christopher M Tipton et al. NATURE IMMUNOLOGY
- Genetics and pathogenesis of systemic lupus erythematosus and lupus nephritis
- (2015) Chandra Mohan et al. Nature Reviews Nephrology
- The B-cell antigen receptor integrates adaptive and innate immune signals
- (2015) Kevin L. Otipoby et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TLR7 Influences Germinal Center Selection in Murine SLE
- (2015) Alexis Boneparth et al. PLoS One
- Dosage of X-linked Toll-like receptor 8 determines gender differences in the development of systemic lupus erythematosus
- (2014) Benjamin R. Umiker et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Effects of Hydroxychloroquine on Symptomatic Improvement in Primary Sjögren Syndrome
- (2014) Jacques-Eric Gottenberg et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- TLR-Activated B Cells Suppress T Cell-Mediated Autoimmunity
- (2014) V. Lampropoulou et al. JOURNAL OF IMMUNOLOGY
- Opposing Impact of B Cell-Intrinsic TLR7 and TLR9 Signals on Autoantibody Repertoire and Systemic Inflammation
- (2014) S. W. Jackson et al. JOURNAL OF IMMUNOLOGY
- B Cell–Intrinsic TLR7 Signaling Is Essential for the Development of Spontaneous Germinal Centers
- (2014) Chetna Soni et al. JOURNAL OF IMMUNOLOGY
- TLR8 on dendritic cells and TLR9 on B cells restrain TLR7-mediated spontaneous autoimmunity in C57BL/6 mice
- (2014) B. Desnues et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Active systemic lupus erythematosus is associated with a reduced cytokine production by B cells in response to TLR9 stimulation
- (2014) Julia Sieber et al. ARTHRITIS RESEARCH & THERAPY
- Genetic variations in Toll-like receptors (TLRs 3/7/8) are associated with systemic lupus erythematosus in a Taiwanese population
- (2014) Chin-Man Wang et al. Scientific Reports
- C-Reactive Protein Inhibits Plasmacytoid Dendritic Cell Interferon Responses to Autoantibody Immune Complexes
- (2013) Carolyn Mold et al. ARTHRITIS AND RHEUMATISM
- B cells
- (2013) Thomas Dörner et al. CURRENT OPINION IN RHEUMATOLOGY
- Signals via the Adaptor MyD88 in B Cells and DCs Make Distinct and Synergistic Contributions to Immune Activation and Tissue Damage in Lupus
- (2013) Lino L. Teichmann et al. IMMUNITY
- The novel TLR-9 agonist QbG10 shows clinical efficacy in persistent allergic asthma
- (2013) Kai-Michael Beeh et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Requirement for MyD88 Signaling in B Cells and Dendritic Cells for Germinal Center Anti-Nuclear Antibody Production in Lyn-Deficient Mice
- (2013) Z. Hua et al. JOURNAL OF IMMUNOLOGY
- TRAF5 Negatively Regulates TLR Signaling in B Lymphocytes
- (2013) C. M. Buchta et al. JOURNAL OF IMMUNOLOGY
- Molecular Basis of 9G4 B Cell Autoreactivity in Human Systemic Lupus Erythematosus
- (2013) C. Richardson et al. JOURNAL OF IMMUNOLOGY
- B lymphocytes enhance interferon-α production by plasmacytoid dendritic cells
- (2012) Olof Berggren et al. ARTHRITIS AND RHEUMATISM
- Results of an Investigator-Initiated Single-Blind Split-Face Comparison of Photodynamic Therapy and 5% Imiquimod Cream for the Treatment of Actinic Keratoses
- (2012) Jason Hadley et al. DERMATOLOGIC SURGERY
- A randomized pilot comparative study of topical methyl aminolevulinate photodynamic therapy versus imiquimod 5% versus sequential application of both therapies in immunocompetent patients with actinic keratosis: Clinical and histologic outcomes
- (2012) Carlos Serra-Guillén et al. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
- Dual signaling by innate and adaptive immune receptors is required for TLR7-induced B-cell-mediated autoimmunity
- (2012) E. R. Walsh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Investigation of the role of endosomal Toll-like receptors in murine collagen-induced arthritis reveals a potential role for TLR7 in disease maintenance
- (2012) Saba Alzabin et al. ARTHRITIS RESEARCH & THERAPY
- Toll-like receptor 7 (TLR7)-driven accumulation of a novel CD11c+ B-cell population is important for the development of autoimmunity
- (2011) A. V. Rubtsov et al. BLOOD
- Unc93B1 Restricts Systemic Lethal Inflammation by Orchestrating Toll-like Receptor 7 and 9 Trafficking
- (2011) Ryutaro Fukui et al. IMMUNITY
- WASp-deficient B cells play a critical, cell-intrinsic role in triggering autoimmunity
- (2011) Shirly Becker-Herman et al. JOURNAL OF EXPERIMENTAL MEDICINE
- B cell-derived IL-10 suppresses inflammatory disease in Lyn-deficient mice
- (2011) P. Scapini et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Disturbances of apoptotic cell clearance in systemic lupus erythematosus
- (2011) Wen-Hai Shao et al. ARTHRITIS RESEARCH & THERAPY
- Association of TLR7 copy number variation with susceptibility to childhood-onset systemic lupus erythematosus in Mexican population
- (2010) H. Garcia-Ortiz et al. ANNALS OF THE RHEUMATIC DISEASES
- BCR-mediated uptake of antigen linked to TLR9 ligand stimulates B-cell proliferation and antigen-specific plasma cell formation
- (2009) J. Eckl-Dorna et al. BLOOD
- Unc93B1 biases Toll-like receptor responses to nucleic acid in dendritic cells toward DNA- but against RNA-sensing
- (2009) Ryutaro Fukui et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The Development and Function of Regulatory B Cells Expressing IL-10 (B10 Cells) Requires Antigen Receptor Diversity and TLR Signals
- (2009) K. Yanaba et al. JOURNAL OF IMMUNOLOGY
- Origins and functional impact of copy number variation in the human genome
- (2009) Donald F. Conrad et al. NATURE
- TRAF5 is a critical mediator of in vitro signals and in vivo functions of LMP1, the viral oncogenic mimic of CD40
- (2009) Z. J. Kraus et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Innate and Adaptive Immunity Cooperate Flexibly to Maintain Host-Microbiota Mutualism
- (2009) E. Slack et al. SCIENCE
- Nucleic acid-sensing Toll-like receptors: Beyond ligand search☆
- (2008) K MIYAKE ADVANCED DRUG DELIVERY REVIEWS
- Klinefelter's syndrome (47,XXY) in male systemic lupus erythematosus patients: Support for the notion of a gene-dose effect from the X chromosome
- (2008) R. Hal Scofield et al. ARTHRITIS AND RHEUMATISM
- Comparison of human B cell activation by TLR7 and TLR9 agonists
- (2008) John A Hanten et al. BMC IMMUNOLOGY
- Yaaautoimmune phenotypes are conferred by overexpression of TLR7
- (2008) Anna‐Marie Fairhurst et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Toll-like receptor 7–induced naive human B-cell differentiation and immunoglobulin production
- (2008) Mark C. Glaum et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- IRF9 and STAT1 are required for IgG autoantibody production and B cell expression of TLR7 in mice
- (2008) Donna L. Thibault et al. JOURNAL OF CLINICAL INVESTIGATION
- Pyogenic Bacterial Infections in Humans with MyD88 Deficiency
- (2008) H. von Bernuth et al. SCIENCE
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started