标题
Multifaceted activities of transcription factor EB in cancer onset and progression
作者
关键词
-
出版物
Molecular Oncology
Volume -, Issue -, Pages -
出版商
Wiley
发表日期
2020-11-30
DOI
10.1002/1878-0261.12867
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Mesenchymal stem cells elicit macrophages into M2 phenotype via improving transcription factor EB-mediated autophagy to alleviate diabetic nephropathy
- (2020) Yujia Yuan et al. STEM CELLS
- Fasting-induced FGF21 signaling activates hepatic autophagy and lipid degradation via JMJD3 histone demethylase
- (2020) Sangwon Byun et al. Nature Communications
- Sex differences in autophagy-mediated diseases: toward precision medicine
- (2020) Dangtong Shang et al. Autophagy
- Loss of function of transcription factor EB remodels lipid metabolism and cell death pathways in the cardiomyocyte
- (2020) Purvi C. Trivedi et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Non-Apoptotic Cell Death Signaling Pathways in Melanoma
- (2020) Mariusz L. Hartman INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The regulation of TFEB in lipid homeostasis of non-alcoholic fatty liver disease: Molecular mechanism and promising therapeutic targets
- (2020) Shenglan Yu et al. LIFE SCIENCES
- TFEB regulates murine liver cell fate during development and regeneration
- (2020) Nunzia Pastore et al. Nature Communications
- TFEB Modulates p21/WAF1/CIP1 during the DNA Damage Response
- (2020) Sandra Pisonero-Vaquero et al. Cells
- The unfolded protein response regulates hepatic autophagy by sXBP1-mediated activation of TFEB
- (2020) Zeyuan Zhang et al. Autophagy
- CDK4/6 regulate lysosome biogenesis through TFEB/TFE3
- (2020) Qiuyuan Yin et al. JOURNAL OF CELL BIOLOGY
- Deletion of Calcineurin in Schwann Cells Does Not Affect Developmental Myelination, But Reduces Autophagy and Delays Myelin Clearance after Peripheral Nerve Injury
- (2020) Chelsey B. Reed et al. JOURNAL OF NEUROSCIENCE
- Wnt/β-catenin signaling axis is required for TFEB-mediated gastric cancer metastasis and epithelial-mesenchymal transition
- (2020) Shuxuan Li et al. MOLECULAR CANCER RESEARCH
- A substrate-specific mTORC1 pathway underlies Birt–Hogg–Dubé syndrome
- (2020) Gennaro Napolitano et al. NATURE
- An FGF15/19-TFEB regulatory loop controls hepatic cholesterol and bile acid homeostasis
- (2020) Yifeng Wang et al. Nature Communications
- TFEB is a master regulator of tumor-associated macrophages in breast cancer
- (2020) Yong Li et al. Journal for ImmunoTherapy of Cancer
- p27 controls Ragulator and mTOR activity in amino acid-deprived cells to regulate the autophagy–lysosomal pathway and coordinate cell cycle and cell growth
- (2020) Ada Nowosad et al. NATURE CELL BIOLOGY
- MITF and TFEB cross-regulation in melanoma cells
- (2020) Josué Ballesteros-Álvarez et al. PLoS One
- Biological Functions of Autophagy Genes: A Disease Perspective
- (2019) Beth Levine et al. CELL
- The Transcription Factors TFEB and TFE3 Link the FLCN-AMPK Signaling Axis to Innate Immune Response and Pathogen Resistance
- (2019) Leeanna El-Houjeiri et al. Cell Reports
- MITF has a central role in regulating starvation-induced autophagy in melanoma
- (2019) Katrin Möller et al. Scientific Reports
- Autophagy in endothelial cells and tumor angiogenesis
- (2019) Marco B. Schaaf et al. CELL DEATH AND DIFFERENTIATION
- Endothelial TFEB (Transcription Factor EB) Restrains IKK (IκB Kinase)-p65 Pathway to Attenuate Vascular Inflammation in Diabetic db/db Mice
- (2019) Wencong Song et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- MITF—the first 25 years
- (2019) Colin R. Goding et al. GENES & DEVELOPMENT
- Transcriptional regulation of autophagy-lysosomal function in BRAF-driven melanoma progression and chemoresistance
- (2019) Shun Li et al. Nature Communications
- TFEB mediates immune evasion and resistance to mTOR inhibition of renal cell carcinoma via induction of PD-L1
- (2019) Cai Zhang et al. CLINICAL CANCER RESEARCH
- TFEB-driven autophagy potentiates TGF-β induced migration in pancreatic cancer cells
- (2019) Ruizhi He et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- YY1 cooperates with TFEB to regulate autophagy and lysosomal biogenesis in melanoma
- (2019) Jing Du et al. MOLECULAR CARCINOGENESIS
- Clinicopathologic and Molecular Analysis of the TFEB Fusion Variant Reveals New Members of TFEB Translocation Renal Cell Carcinomas (RCCs)
- (2019) Qiu-Yuan Xia et al. AMERICAN JOURNAL OF SURGICAL PATHOLOGY
- Acetyltransferase GCN5 regulates autophagy and lysosome biogenesis by targeting TFEB
- (2019) Yusha Wang et al. EMBO REPORTS
- MYC competes with MiT/TFE in regulating lysosomal biogenesis and autophagy through an epigenetic rheostat
- (2019) Ida Annunziata et al. Nature Communications
- A lysosome independent role for TFEB in activating DNA repair and inhibiting apoptosis in breast cancer cells
- (2019) Logan Slade et al. BIOCHEMICAL JOURNAL
- Inhibition of WNT-CTNNB1 signaling upregulates SQSTM1 and sensitizes glioblastoma cells to autophagy blockers
- (2018) Mireia Nàger et al. Autophagy
- Endothelial TFEB (Transcription Factor EB) Positively Regulates Postischemic AngiogenesisNovelty and Significance
- (2018) Yanbo Fan et al. CIRCULATION RESEARCH
- Protein phosphatase 2A stimulates activation of TFEB and TFE3 transcription factors in response to oxidative stress
- (2018) José A. Martina et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Lysosomal Protein Lamtor1 Controls Innate Immune Responses via Nuclear Translocation of Transcription Factor EB
- (2018) Yoshitomo Hayama et al. JOURNAL OF IMMUNOLOGY
- Chloroquine modulates antitumor immune response by resetting tumor-associated macrophages toward M1 phenotype
- (2018) Degao Chen et al. Nature Communications
- MAP4K3 mediates amino acid-dependent regulation of autophagy via phosphorylation of TFEB
- (2018) Cynthia L. Hsu et al. Nature Communications
- A TFEB nuclear export signal integrates amino acid supply and glucose availability
- (2018) Linxin Li et al. Nature Communications
- Nuclear Export Inhibition Enhances HLH-30/TFEB Activity, Autophagy, and Lifespan
- (2018) Melissa J. Silvestrini et al. Cell Reports
- mTOR-dependent phosphorylation controls TFEB nuclear export
- (2018) Gennaro Napolitano et al. Nature Communications
- The Lysosomal Transcription Factor TFEB Represses Myelination Downstream of the Rag-Ragulator Complex
- (2018) Ana M. Meireles et al. DEVELOPMENTAL CELL
- TFEB controls vascular development by regulating the proliferation of endothelial cells
- (2018) Gabriella Doronzo et al. EMBO JOURNAL
- High expression of TFEB is associated with aggressive clinical features in colorectal cancer
- (2018) Jing Liang et al. OncoTargets and Therapy
- DAF-16/FOXO and HLH-30/TFEB function as combinatorial transcription factors to promote stress resistance and longevity
- (2018) Xin-Xuan Lin et al. Nature Communications
- The transcription factors TFE3 and TFEB amplify p53 dependent transcriptional programs in response to DNA damage
- (2018) Eutteum Jeong et al. eLife
- Comprehensive study of three novel cases of TFEB -amplified renal cell carcinoma and review of the literature: Evidence for a specific entity with poor outcome
- (2017) Lionel Mendel et al. GENES CHROMOSOMES & CANCER
- Decorin-evoked paternally expressed gene 3 (PEG3) is an upstream regulator of the transcription factor EB (TFEB) in endothelial cell autophagy
- (2017) Thomas Neill et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TFEB-VEGFA (6p21.1) co-amplified renal cell carcinoma: a distinct entity with potential implications for clinical management
- (2017) Sounak Gupta et al. MODERN PATHOLOGY
- The MiTF/TFE Family of Transcription Factors: Master Regulators of Organelle Signaling, Metabolism, and Stress Adaptation
- (2017) Logan Slade et al. MOLECULAR CANCER RESEARCH
- Elements of cancer immunity and the cancer–immune set point
- (2017) Daniel S. Chen et al. NATURE
- Tumour-associated macrophages as treatment targets in oncology
- (2017) Alberto Mantovani et al. Nature Reviews Clinical Oncology
- Transcriptional activation of RagD GTPase controls mTORC1 and promotes cancer growth
- (2017) Chiara Di Malta et al. SCIENCE
- Adrenergic nerves activate an angio-metabolic switch in prostate cancer
- (2017) Ali H. Zahalka et al. SCIENCE
- TFEB inhibits endothelial cell inflammation and reduces atherosclerosis
- (2017) Haocheng Lu et al. Science Signaling
- mTORC1-independent TFEB activation via Akt inhibition promotes cellular clearance in neurodegenerative storage diseases
- (2017) Michela Palmieri et al. Nature Communications
- TFEB inhibits endothelial cell inflammation and reduces atherosclerosis
- (2017) Haocheng Lu et al. Science Signaling
- Transcriptional factor EB regulates macrophage polarization in the tumor microenvironment
- (2017) Liang Fang et al. OncoImmunology
- Transcriptional regulation of core autophagy and lysosomal genes by the androgen receptor promotes prostate cancer progression
- (2016) Alicia M. Blessing et al. Autophagy
- TFEB and TFE3 cooperate in the regulation of the innate immune response in activated macrophages
- (2016) Nunzia Pastore et al. Autophagy
- EMT: 2016
- (2016) M. Angela Nieto et al. CELL
- Autophagy, Inflammation, and Immunity: A Troika Governing Cancer and Its Treatment
- (2016) Zhenyu Zhong et al. CELL
- Phagocytosis Enhances Lysosomal and Bactericidal Properties by Activating the Transcription Factor TFEB
- (2016) Matthew A. Gray et al. CURRENT BIOLOGY
- Identification of Susceptibility Loci and Genes for Colorectal Cancer Risk
- (2016) Chenjie Zeng et al. GASTROENTEROLOGY
- AMPK governs lineage specification through Tfeb-dependent regulation of lysosomes
- (2016) Nathan P. Young et al. GENES & DEVELOPMENT
- TFEB regulates PER3 expression via glucose-dependent effects on CLOCK/BMAL1
- (2016) Wenwen Luo et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Role of TFEB-driven autophagy regulation in pancreatic cancer treatment
- (2016) KATHRIN KLEIN et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- TFEB at a glance
- (2016) Gennaro Napolitano et al. JOURNAL OF CELL SCIENCE
- Protein kinase C controls lysosome biogenesis independently of mTORC1
- (2016) Yang Li et al. NATURE CELL BIOLOGY
- PPARs in obesity-induced T2DM, dyslipidaemia and NAFLD
- (2016) Barbara Gross et al. Nature Reviews Endocrinology
- Chronic stress increases experimental pancreatic cancer growth, reduces survival and can be antagonised by beta-adrenergic receptor blockade
- (2016) Lars Ivo Partecke et al. PANCREATOLOGY
- Present Yourself! By MHC Class I and MHC Class II Molecules
- (2016) Kenneth L. Rock et al. TRENDS IN IMMUNOLOGY
- Mondo complexes regulate TFEB via TOR inhibition to promote longevity in response to gonadal signals
- (2016) Shuhei Nakamura et al. Nature Communications
- Novel role of miR-29a in pancreatic cancer autophagy and its therapeutic potential
- (2016) Jason J. Kwon et al. Oncotarget
- Deacetylation of TFEB promotes fibrillar Aβ degradation by upregulating lysosomal biogenesis in microglia
- (2016) Jintao Bao et al. Protein & Cell
- Modelling TFE renal cell carcinoma in mice reveals a critical role of WNT signaling
- (2016) Alessia Calcagnì et al. eLife
- Lysosomal Storage Diseases: From Pathophysiology to Therapy
- (2015) Giancarlo Parenti et al. Annual Review of Medicine
- Lysosomal Physiology
- (2015) Haoxing Xu et al. Annual Review of Physiology
- New insights into PGC-1 coactivators: redefining their role in the regulation of mitochondrial function and beyond
- (2015) Josep A. Villena FEBS Journal
- Birt-Hogg-Dubé syndrome: Clinical and molecular aspects of recently identified kidney cancer syndrome
- (2015) Hisashi Hasumi et al. INTERNATIONAL JOURNAL OF UROLOGY
- Glycogen Synthase Kinase-3 (GSK3) Inhibition Induces Prosurvival Autophagic Signals in Human Pancreatic Cancer Cells
- (2015) Benoît Marchand et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Transcription Factor EB (TFEB) Regulates Osteoblast Differentiation Through ATF4/CHOP-Dependent Pathway
- (2015) Erika Yoneshima et al. JOURNAL OF CELLULAR PHYSIOLOGY
- The role for autophagy in cancer
- (2015) Eileen White JOURNAL OF CLINICAL INVESTIGATION
- The interaction of anticancer therapies with tumor-associated macrophages
- (2015) Alberto Mantovani et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Increased expression of transcription factor EB (TFEB) is associated with autophagy, migratory phenotype and poor prognosis in non-small cell lung cancer
- (2015) Alexandra Giatromanolaki et al. LUNG CANCER
- Transcriptional control of autophagy–lysosome function drives pancreatic cancer metabolism
- (2015) Rushika M. Perera et al. NATURE
- Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB
- (2015) Diego L. Medina et al. NATURE CELL BIOLOGY
- The transcription factor TFEB acts as a molecular switch that regulates exogenous antigen-presentation pathways
- (2015) Mohammad Samie et al. NATURE IMMUNOLOGY
- Neoantigens in cancer immunotherapy
- (2015) T. N. Schumacher et al. SCIENCE
- MiT family translocation renal cell carcinoma
- (2015) Pedram Argani SEMINARS IN DIAGNOSTIC PATHOLOGY
- Pharmaceutical screen identifies novel target processes for activation of autophagy with a broad translational potential
- (2015) Santosh Chauhan et al. Nature Communications
- Atg7 Overcomes Senescence and Promotes Growth of BrafV600E-Driven Melanoma
- (2015) X. Xie et al. Cancer Discovery
- Pancreatic Adenocarcinoma
- (2015) David P. Ryan et al. NEW ENGLAND JOURNAL OF MEDICINE
- Autophagy suppresses melanoma tumorigenesis by inducing senescence
- (2014) He Liu et al. Autophagy
- Innate Host Defense Requires TFEB-Mediated Transcription of Cytoprotective and Antimicrobial Genes
- (2014) Orane Visvikis et al. IMMUNITY
- Transcriptional regulation of autophagy by an FXR–CREB axis
- (2014) Sunmi Seok et al. NATURE
- Transcriptional Regulation and Its Misregulation in Disease
- (2013) Tong Ihn Lee et al. CELL
- A RANKL-PKC -TFEB signaling cascade is necessary for lysosomal biogenesis in osteoclasts
- (2013) M. Ferron et al. GENES & DEVELOPMENT
- Recruitment of folliculin to lysosomes supports the amino acid–dependent activation of Rag GTPases
- (2013) Constance S. Petit et al. JOURNAL OF CELL BIOLOGY
- Rag GTPases mediate amino acid–dependent recruitment of TFEB and MITF to lysosomes
- (2013) Jose A. Martina et al. JOURNAL OF CELL BIOLOGY
- The Folliculin Tumor Suppressor Is a GAP for the RagC/D GTPases That Signal Amino Acid Levels to mTORC1
- (2013) Zhi-Yang Tsun et al. MOLECULAR CELL
- TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop
- (2013) Carmine Settembre et al. NATURE CELL BIOLOGY
- A Tumor Suppressor Complex with GAP Activity for the Rag GTPases That Signal Amino Acid Sufficiency to mTORC1
- (2013) L. Bar-Peled et al. SCIENCE
- The TFEB orthologue HLH-30 regulates autophagy and modulates longevity in Caenorhabditis elegans
- (2013) Louis R. Lapierre et al. Nature Communications
- The myosin motor Myo1c is required for VEGFR2 delivery to the cell surface and for angiogenic signaling
- (2012) Ajit Tiwari et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB
- (2012) Jose A. Martina et al. Autophagy
- Ragulator Is a GEF for the Rag GTPases that Signal Amino Acid Levels to mTORC1
- (2012) Liron Bar-Peled et al. CELL
- A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB
- (2012) Carmine Settembre et al. EMBO JOURNAL
- The Transcription Factor TFEB Links mTORC1 Signaling to Transcriptional Control of Lysosome Homeostasis
- (2012) A. Roczniak-Ferguson et al. Science Signaling
- The Initial Hours of Metastasis: The Importance of Cooperative Host-Tumor Cell Interactions during Hematogenous Dissemination
- (2012) M. Labelle et al. Cancer Discovery
- MicroRNA-16 and MicroRNA-424 Regulate Cell-Autonomous Angiogenic Functions in Endothelial Cells via Targeting Vascular Endothelial Growth Factor Receptor-2 and Fibroblast Growth Factor Receptor-1
- (2011) Aránzazu Chamorro-Jorganes et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Neurogenesis in colorectal cancer is a marker of aggressive tumor behavior and poor outcomes
- (2011) Daniel Albo et al. CANCER
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Embryonic expression of zebrafish MiT family genes tfe3b, tfeb, and tfec
- (2011) James A. Lister et al. DEVELOPMENTAL DYNAMICS
- Regulation of TFEB and V-ATPases by mTORC1
- (2011) Samuel Peña-Llopis et al. EMBO JOURNAL
- Characterization of the CLEAR network reveals an integrated control of cellular clearance pathways
- (2011) Michela Palmieri et al. HUMAN MOLECULAR GENETICS
- WT1 in disease: shifting the epithelial-mesenchymal balance
- (2011) Eve Miller-Hodges et al. JOURNAL OF PATHOLOGY
- Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases
- (2011) Peter Carmeliet et al. NATURE REVIEWS DRUG DISCOVERY
- TFEB Links Autophagy to Lysosomal Biogenesis
- (2011) C. Settembre et al. SCIENCE
- Ragulator-Rag Complex Targets mTORC1 to the Lysosomal Surface and Is Necessary for Its Activation by Amino Acids
- (2010) Yasemin Sancak et al. CELL
- A Gene Network Regulating Lysosomal Biogenesis and Function
- (2009) Marco Sardiello et al. SCIENCE
- Fat and Beyond: The Diverse Biology of PPARγ
- (2008) Peter Tontonoz et al. Annual Review of Biochemistry
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