Decorin-evoked paternally expressed gene 3 (PEG3) is an upstream regulator of the transcription factor EB (TFEB) in endothelial cell autophagy

Decorin-inducible Peg3 Evokes Beclin 1-mediated Autophagy and Thrombospondin 1-mediated Angiostasis

(2017) Annabel Torres et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Decorin as a multivalent therapeutic agent against cancer

(2016) Thomas Neill et al.   ADVANCED DRUG DELIVERY REVIEWS

Endorepellin-evoked Autophagy Contributes to Angiostasis

(2016) Atul Goyal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

EphA2 is a functional receptor for the growth factor progranulin

(2016) Thomas Neill et al.   JOURNAL OF CELL BIOLOGY

Decorin interacting network: A comprehensive analysis of decorin-binding partners and their versatile functions

(2016) Maria A. Gubbiotti et al.   MATRIX BIOLOGY

The extracellular matrix: Tools and insights for the “omics” era

(2016) Alexandra Naba et al.   MATRIX BIOLOGY

Skin tissue repair: Matrix microenvironmental influences

(2016) Alan Wells et al.   MATRIX BIOLOGY

AMPK–SKP2–CARM1 signalling cascade in transcriptional regulation of autophagy

(2016) Hi-Jai R. Shin et al.   NATURE

Decoding the Matrix: Instructive Roles of Proteoglycan Receptors

(2015) Thomas Neill et al.   BIOCHEMISTRY

The role of perlecan and endorepellin in the control of tumor angiogenesis and endothelial cell autophagy

(2015) Stephen Douglass et al.   CONNECTIVE TISSUE RESEARCH

Systemic Delivery of an Oncolytic Adenovirus Expressing Decorin for the Treatment of Breast Cancer Bone Metastases

(2015) Yuefeng Yang et al.   HUMAN GENE THERAPY

Pivotal role for decorin in angiogenesis

(2015) Hannu Järveläinen et al.   MATRIX BIOLOGY

Multilevel regulation of matrix metalloproteinases in tissue homeostasis indicates their molecular specificity in vivo

(2015) Jean Gaffney et al.   MATRIX BIOLOGY

Proteoglycans regulate autophagy via outside-in signaling: an emerging new concept

(2015) Maria A. Gubbiotti et al.   MATRIX BIOLOGY

Matrix remodeling by MMPs during wound repair

(2015) Maryam G. Rohani et al.   MATRIX BIOLOGY

Decorin is an autophagy-inducible proteoglycan and is required for proper in vivo autophagy

(2015) Maria A. Gubbiotti et al.   MATRIX BIOLOGY

Proteoglycan form and function: A comprehensive nomenclature of proteoglycans

(2015) Renato V. Iozzo et al.   MATRIX BIOLOGY

Matrix metalloproteinases in liver injury, repair and fibrosis

(2015) Sergio Duarte et al.   MATRIX BIOLOGY

Nutrient-sensing mechanisms and pathways

(2015) Alejo Efeyan et al.   NATURE

Instructive Roles of Extracellular Matrix on Autophagy

(2014) Thomas Neill et al.   AMERICAN JOURNAL OF PATHOLOGY

The systemic delivery of an oncolytic adenovirus expressing decorin inhibits bone metastasis in a mouse model of human prostate cancer

(2014) W Xu et al.   GENE THERAPY

The Phytoestrogen Genistein Modulates Lysosomal Metabolism and Transcription Factor EB (TFEB) Activation

(2014) Marta Moskot et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Decorin Induces Mitophagy in Breast Carcinoma Cells via Peroxisome Proliferator-activated Receptor γ Coactivator-1α (PGC-1α) and Mitostatin

(2014) Thomas Neill et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endorepellin Evokes Autophagy in Endothelial Cells

(2014) Chiara Poluzzi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Decorin activates AMPK, an energy sensor kinase, to induce autophagy in endothelial cells

(2014) Atul Goyal et al.   MATRIX BIOLOGY

Transcriptional regulation of autophagy by an FXR–CREB axis

(2014) Sunmi Seok et al.   NATURE

The Nutrient-Responsive Transcription Factor TFE3 Promotes Autophagy, Lysosomal Biogenesis, and Clearance of Cellular Debris

(2014) J. A. Martina et al.   Science Signaling

Reactive Oxygen Species in Inflammation and Tissue Injury

(2013) Manish Mittal et al.   ANTIOXIDANTS & REDOX SIGNALING

AMPK connects energy stress to PIK3C3/VPS34 regulation

(2013) Joungmok Kim et al.   Autophagy

Decorin has an appetite for endothelial cell autophagy

(2013) Thomas Neill et al.   Autophagy

Biological interplay between proteoglycans and their innate immune receptors in inflammation

(2013) Helena Frey et al.   FEBS Journal

The histone H4 lysine 16 acetyltransferase hMOF regulates the outcome of autophagy

(2013) Jens Füllgrabe et al.   NATURE

TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop

(2013) Carmine Settembre et al.   NATURE CELL BIOLOGY

Signals from the lysosome: a control centre for cellular clearance and energy metabolism

(2013) Carmine Settembre et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The return of the nucleus: transcriptional and epigenetic control of autophagy

(2013) Jens Füllgrabe et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Associations between Methylation of Paternally Expressed Gene 3 (PEG3), Cervical Intraepithelial Neoplasia and Invasive Cervical Cancer

(2013) Monica D. Nye et al.   PLoS One

Structure of the SCAN Domain of Human Paternally Expressed Gene 3 Protein

(2013) Vadim Rimsa et al.   PLoS One

Decorin causes autophagy in endothelial cells via Peg3

(2013) S. Buraschi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB

(2012) Carmine Settembre et al.   EMBO JOURNAL

Endorepellin Affects Angiogenesis by Antagonizing Diverse Vascular Endothelial Growth Factor Receptor 2 (VEGFR2)-evoked Signaling Pathways

(2012) Atul Goyal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Decorin Protein Core Affects the Global Gene Expression Profile of the Tumor Microenvironment in a Triple-Negative Orthotopic Breast Carcinoma Xenograft Model

(2012) Simone Buraschi et al.   PLoS One

The Transcription Factor TFEB Links mTORC1 Signaling to Transcriptional Control of Lysosome Homeostasis

(2012) A. Roczniak-Ferguson et al.   Science Signaling

TFEB regulates autophagy: An integrated coordination of cellular degradation and recycling processes

(2011) Carmine Settembre et al.   Autophagy

Characterization of the CLEAR network reveals an integrated control of cellular clearance pathways

(2011) Michela Palmieri et al.   HUMAN MOLECULAR GENETICS

Endorepellin, the Angiostatic Module of Perlecan, Interacts with Both the α2β1 Integrin and Vascular Endothelial Growth Factor Receptor 2 (VEGFR2)

(2011) Atul Goyal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Decorin Antagonizes the Angiogenic Network

(2011) Thomas Neill et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of AMPK-mTOR-Ulk1/2 in the Regulation of Autophagy: Cross Talk, Shortcuts, and Feedbacks

(2011) S. Alers et al.   MOLECULAR AND CELLULAR BIOLOGY

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

(2011) Joungmok Kim et al.   NATURE CELL BIOLOGY

TFEB Links Autophagy to Lysosomal Biogenesis

(2011) C. Settembre et al.   SCIENCE

Signaling by the Matrix Proteoglycan Decorin Controls Inflammation and Cancer Through PDCD4 and MicroRNA-21

(2011) R. Merline et al.   Science Signaling

Decorin Antagonizes Met Receptor Activity and Down-regulates β-Catenin and Myc Levels

(2010) Simone Buraschi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Imprinted GenePEG3Inhibits Wnt Signaling and Regulates Glioma Growth

(2010) Xiuli Jiang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Termination of autophagy and reformation of lysosomes regulated by mTOR

(2010) Li Yu et al.   NATURE

Autophagy in mammalian development and differentiation

(2010) Noboru Mizushima et al.   NATURE CELL BIOLOGY

The Association of AMPK with ULK1 Regulates Autophagy

(2010) Jong Woo Lee et al.   PLoS One

Regulation Mechanisms and Signaling Pathways of Autophagy

(2009) Congcong He et al.   Annual Review of Genetics

mTOR regulates autophagy-associated genes downstream of p73

(2009) Jennifer M. Rosenbluth et al.   Autophagy

Mammalian autophagy: core molecular machinery and signaling regulation

(2009) Zhifen Yang et al.   CURRENT OPINION IN CELL BIOLOGY

An ATP-competitive Mammalian Target of Rapamycin Inhibitor Reveals Rapamycin-resistant Functions of mTORC1

(2009) Carson C. Thoreen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy regulates lipid metabolism

(2009) Rajat Singh et al.   NATURE

A Gene Network Regulating Lysosomal Biogenesis and Function

(2009) Marco Sardiello et al.   SCIENCE

Imprinted tumor suppressor genesARHI andPEG3 are the most frequently down-regulated in human ovarian cancers by loss of heterozygosity and promoter methylation

(2008) Weiwei Feng et al.   CANCER

AMP-activated protein kinase and human cancer: cancer metabolism revisited

(2008) F P Kuhajda   INTERNATIONAL JOURNAL OF OBESITY

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE