Host Immune Defense upon Fungal Infections with Mucorales: Pathogen-Immune Cell Interactions as Drivers of Inflammatory Responses

Functional surface proteomic profiling reveals the host heat‐shock protein A8 as a mediator of Lichtheimia corymbifera recognition by murine alveolar macrophages

(2020) Mohamed I. Abdelwahab Hassan et al.   ENVIRONMENTAL MICROBIOLOGY

Salt generates antiinflammatory Th17 cells but amplifies pathogenicity in proinflammatory cytokine microenvironments

(2020) Julia Matthias et al.   JOURNAL OF CLINICAL INVESTIGATION

Comparative Analysis of Inflammatory Cytokine Release and Alveolar Epithelial Barrier Invasion in a Transwell® Bilayer Model of Mucormycosis

(2019) Stanislav Belic et al.   Frontiers in Microbiology

Pathogenicity patterns of mucormycosis: epidemiology, interaction with immune cells and virulence factors

(2019) Mohamed I Abdelwahab Hassan et al.   MEDICAL MYCOLOGY

Anti-CotH3 antibodies protect mice from mucormycosis by prevention of invasion and augmenting opsonophagocytosis

(2019) Teclegiorgis Gebremariam et al.   Science Advances

Impairment of Th cell response in Card9 knockout mice with cutaneous mucormycosis caused by Rhizopus arrhizus

(2019) Lingyue Sun et al.   EXPERIMENTAL DERMATOLOGY

GM-CSF-Dependent Inflammatory Pathways

(2019) John A. Hamilton   Frontiers in Immunology

Multiple Signaling Pathways Involved in Human Dendritic Cell Maturation Are Affected by the Fungal Quorum-Sensing Molecule Farnesol

(2019) Wolfgang Vivas et al.   JOURNAL OF IMMUNOLOGY

Global guideline for the diagnosis and management of mucormycosis: an initiative of the European Confederation of Medical Mycology in cooperation with the Mycoses Study Group Education and Research Consortium

(2019) Oliver A Cornely et al.   LANCET INFECTIOUS DISEASES

Human T Cell Development, Localization, and Function throughout Life

(2018) Brahma V. Kumar et al.   IMMUNITY

Elevated tissue sodium deposition in patients with type 2 diabetes on hemodialysis detected by 23 Na magnetic resonance imaging

(2018) Christoph Kopp et al.   KIDNEY INTERNATIONAL

Neutrophil extracellular traps in fungal infection

(2018) Constantin F. Urban et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Phagocytes as central players in the defence against invasive fungal infection

(2018) Kerstin Hünniger et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

A New Method for Reactivating and Expanding T Cells Specific for Rhizopus oryzae

(2018) Paul Castillo et al.   Molecular Therapy-Methods & Clinical Development

Evaluation of Aspergillus and Mucorales specific T-cells and peripheral blood mononuclear cell cytokine signatures as biomarkers of environmental mold exposure

(2018) Lukas Page et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Iron restriction inside macrophages regulates pulmonary host defense against Rhizopus species

(2018) Angeliki M. Andrianaki et al.   Nature Communications

An Adult Zebrafish Model Reveals that Mucormycosis Induces Apoptosis of Infected Macrophages

(2018) Azucena López-Muñoz et al.   Scientific Reports

Fungal ligands released by innate immune effectors promote inflammasome activation during Aspergillus fumigatus infection

(2018) Benoit Briard et al.   Nature Microbiology

The role of IL-6 in host defence against infections: immunobiology and clinical implications

(2017) Stefan Rose-John et al.   Nature Reviews Rheumatology

Mucorales spores induce a proinflammatory cytokine response in human mononuclear phagocytes and harbor no rodlet hydrophobins

(2017) Sebastian Wurster et al.   Virulence

Increasing incidence of mucormycosis in a large Spanish hospital from 2007 to 2015: Epidemiology and microbiological characterization of the isolates

(2017) Jesús Guinea et al.   PLoS One

Specific pathways mediating inflammasome activation by Candida parapsilosis

(2017) Adél Tóth et al.   Scientific Reports

Alarmin(g) the innate immune system to invasive fungal infections

(2016) Alayna K Caffrey et al.   CURRENT OPINION IN MICROBIOLOGY

Interleukins (from IL-1 to IL-38), interferons, transforming growth factor β, and TNF-α: Receptors, functions, and roles in diseases

(2016) Mübeccel Akdis et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Stress response in medically important Mucorales

(2016) Pankaj Singh et al.   MYCOSES

Different Subsets of T Cells, Memory, Effector Functions, and CAR-T Immunotherapy

(2016) Vita Golubovskaya et al.   Cancers

Invasive infections due to filamentous fungi other than Aspergillus: epidemiology and determinants of mortality

(2015) M. Slavin et al.   CLINICAL MICROBIOLOGY AND INFECTION

T cell subsets and their signature cytokines in autoimmune and inflammatory diseases

(2015) Itay Raphael et al.   CYTOKINE

Natural killer cell-mediated damage of clinical isolates of mucormycetes

(2015) Stanislaw Schmidt et al.   MYCOSES

Adaptive immune responses toCandida albicansinfection

(2015) Jonathan P Richardson et al.   Virulence

Glucose Metabolism Regulates T Cell Activation, Differentiation, and Functions

(2015) Clovis S. Palmer et al.   Frontiers in Immunology

Adaptive Immunity to Fungi

(2014) A. Verma et al.   Cold Spring Harbor Perspectives in Medicine

Iron at the interface of immunity and infection

(2014) Manfred Nairz et al.   Frontiers in Pharmacology

Natural Killer Cells and Antifungal Host Response

(2013) Stanislaw Schmidt et al.   Clinical and Vaccine Immunology

The role of lipid-activated nuclear receptors in shaping macrophage and dendritic cell function: From physiology to pathology

(2013) Mate Kiss et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells

(2013) Markus Kleinewietfeld et al.   NATURE

Treatment of fungal disease in the setting of neutropenia

(2013) T. J. Walsh et al.   Hematology-American Society of Hematology Education Program

Costimulatory Molecules on Immunogenic Versus Tolerogenic Human Dendritic Cells

(2013) Mario Hubo et al.   Frontiers in Immunology

Diagnosis and treatment of mucormycosis in patients with hematological malignancies: guidelines from the 3rd European Conference on Infections in Leukemia (ECIL 3)

(2012) A. Skiada et al.   HAEMATOLOGICA

Rhizopus oryzae hyphae are damaged by human natural killer (NK) cells, but suppress NK cell mediated immunity

(2012) Stanislaw Schmidt et al.   IMMUNOBIOLOGY

Pathogen-induced human TH17 cells produce IFN-γ or IL-10 and are regulated by IL-1β

(2012) Christina E. Zielinski et al.   NATURE

Mucorales-specific T cells emerge in the course of invasive mucormycosis and may be used as a surrogate diagnostic marker in high-risk patients

(2011) L. Potenza et al.   BLOOD

Ferroportin1 deficiency in mouse macrophages impairs iron homeostasis and inflammatory responses

(2011) Z. Zhang et al.   BLOOD

Zygomycosis in Europe: analysis of 230 cases accrued by the registry of the European Confederation of Medical Mycology (ECMM) Working Group on Zygomycosis between 2005 and 2007

(2011) A. Skiada et al.   CLINICAL MICROBIOLOGY AND INFECTION

Evaluation of a 12-color flow cytometry panel to study lymphocyte, monocyte, and dendritic cell subsets in humans

(2010) Patrick Autissier et al.   CYTOMETRY PART A

Potential of anti-Candidaantibodies in immunoprophylaxis

(2010) Jonathan Cabezas et al.   Immunotherapy

Conserved natural IgM antibodies mediate innate and adaptive immunity against the opportunistic fungusPneumocystis murina

(2010) Rekha R. Rapaka et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Generation of IL-23 Producing Dendritic Cells (DCs) by Airborne Fungi Regulates Fungal Pathogenicity via the Induction of TH-17 Responses

(2010) Georgios Chamilos et al.   PLoS One

A clinicopathological study of pulmonary mucormycosis in cancer patients: Extensive angioinvasion but limited inflammatory response

(2009) Ronen Ben-Ami et al.   JOURNAL OF INFECTION

Monocyte Chemoattractant Protein-1 (MCP-1): An Overview

(2009) Satish L. Deshmane et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Functions of natural killer cells

(2008) Eric Vivier et al.   NATURE IMMUNOLOGY