Article
Food Science & Technology
Chaomin Yin, Xin Qiao, Xiuzhi Fan, Zheya Chen, Fen Yao, Defang Shi, Yuhong Li, Hong Gao
Summary: Polysaccharides from Schizophyllum commune, both normal and gamma-irradiated, were shown to prevent weight gain, enhance kidney uric acid metabolism, and increase the concentration of SCFAs in mice. Additionally, these polysaccharides promoted the growth of beneficial gut microbiota and inhibited harmful bacteria. Gamma-irradiated polysaccharides demonstrated better effects in preventing weight gain and modulating the gut microbiota of mice, indicating their potential as a health supplement for obesity prevention.
FOOD RESEARCH INTERNATIONAL
(2022)
Article
Pharmacology & Pharmacy
Qianbo Song, Sau Wan Cheng, Dan Li, Huiyuan Cheng, Yuen Sze Lai, Quanbin Han, Hoi Yan Wu, Pang Chui Shaw, Zhong Zuo
Summary: This study investigated the role of gut microbiota in the hypoglycemic effect of Astragalus membranaceus polysaccharides (AMP) in db/db mice. Treatment with AMP significantly alleviated diabetic symptoms and restored gut microbiota community, leading to increased production of short chain fatty acids (SCFA) in feces. The relative abundance of two intestinal bacteria, Akkermansia and Faecalibaculum, were found to be positively correlated with the hypoglycemic effect of AMP and fecal SCFA production. Furthermore, AMP treatment stimulated the secretion of glucagon-like peptide-1 (GLP-1) and improved intestinal integrity. Mechanistic study revealed that the increased SCFA after AMP treatment could enhance the expression of G protein-coupled receptors 41/43 and tight junction proteins, resulting in the alleviation of diabetic symptoms in db/db mice.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Agriculture, Dairy & Animal Science
Q. Wang, X. F. Wang, T. Xing, J. L. Li, X. D. Zhu, L. Zhang, F. Gao
Summary: The combination of XOS and IAPS can enhance intestinal mucosal immunity and barrier function in broilers by increasing cytokine gene expression, IgA-producing cell production, and modulating cecal microbiota. Additionally, the combination effect of XOS and IAPS is superior to the individual effects of CTC, XOS, or IAPS in the current study.
Article
Biotechnology & Applied Microbiology
Jun Li, Jie Zhao, Yihui Chai, Wen Li, Xiaoqing Liu, Yunzhi Chen
Summary: Through experimental studies, it was found that Astragalus polysaccharide (APS) has a protective effect on septic rats. It can effectively prevent inflammation and organ damage by increasing the activity of the vitamin D axis, inhibiting the production of inflammatory factors, altering the structure of intestinal flora, and increasing the amount of acetic acid and SCFAs in rats.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Microbiology
Ke Ming, Shen Zhuang, Ning Ma, Sha Nan, Qiuhua Li, Mingxing Ding, Yi Ding
Summary: Astragalus polysaccharides (APS) have preventive effects on inflammatory lung injury by improving lung tissue pathology, reducing neutrophil infiltration, inhibiting inflammation, and altering intestinal microbiota composition leading to increased levels of short-chain fatty acids (SCFAs) in the serum.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Food Science & Technology
Ying Li, Juan Qin, Yinghui Cheng, Yuqing Ai, Zhiyi Han, Meng Li, Yanxia Qi, Qiancheng Zhao, Zhibo Li
Summary: The polysaccharide from Patinopecten yessoensis skirt (PS) was found to enhance immune response in mice by increasing serum IgG and IgM levels. Additionally, it modulated gut microbiota, improved SCFAs metabolism, and significantly affected gene expression in the TLR signaling pathway. These findings suggest the potential of PS as a functional ingredient for immune support products.
Article
Pharmacology & Pharmacy
Qian Zhuang, Xin Ye, Shuang Shen, Jinnian Cheng, Yan Shi, Shan Wu, Jie Xia, Min Ning, Zhixia Dong, Xinjian Wan
Summary: Astragalus polysaccharides (APS) showed protective effects against diet-induced cholesterol gallstone (CG) disease by reducing cholesterol absorption, increasing hepatic bile acid synthesis, modulating intestinal receptor activation, and improving gut microbiota composition.
FRONTIERS IN PHARMACOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Yanan Li, Junping Zheng, Yao Wang, Huabing Yang, Lu Cao, Shuiyong Gan, Jun Ma, Hongtao Liu
Summary: This study investigates the role of gut microbiota in the immune-enhancing activity of Astragalus polysaccharides (APS) in mice. The results show that APS can ameliorate immunosuppression in mice and activate Toll-like receptor 4 (TLR4) and mitogen-activated protein kinase (MAPK) pathways. APS treatment also reverses gut microbiota dysbiosis in immunocompromised mice.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Microbiology
Aqsa Ameer, Youqi Cheng, Farrukh Saleem, Aaron Mckenna, Anne Richmond, Ozan Gundogdu, William T. Sloan, Sundus Javed, Umer Zeeshan Ijaz
Summary: This study analyzed the temporal profiles of the broiler cecal microbiome and found that microbial communities exhibited specificity for different environmental variables. Certain microbial genera were identified to be correlated with the bird's age and different metabolic processes. Predicted antimicrobial resistance genes were found to contribute at a stable level.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Bing Yang, Zhiwei Xiong, Meng Lin, Yanjun Yang, Yaping Chen, Jingqi Zeng, Xiaobin Jia, Liang Feng
Summary: This study found that polysaccharides, the main components of Astragalus, a traditional Chinese medicine, can regulate the gut microbiota associated with type 1 diabetes (T1D). It improves gut barrier function, gut microbiota composition, lowers blood glucose, and increases insulin levels. This effect may be related to the production of short-chain fatty acids and the modulation of inflammatory response.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Food Science & Technology
Xinyao Xie, Yongcheng Song, Xiufang Bi, Xiaocui Liu, Yage Xing, Zhenming Che
Summary: Sea buckthorn polysaccharides (SPs) obtained from sea buckthorn pomace have the potential to restore gut microbiota imbalance induced by cefixime, by increasing short-chain fatty acid concentration and the abundance of SCFA-producing bacteria in the gut.
JOURNAL OF FUNCTIONAL FOODS
(2023)
Article
Agriculture, Dairy & Animal Science
J. J. Mallo, C. Sol, M. Puyalto, C. Bortoluzzi, T. J. Applegate, M. J. Villamide
Summary: This study conducted 4 trials to evaluate the impact of different nutrient concentrations and a feed additive on broiler chickens, revealing that nutrient dilution can impair animal performance and intestinal health, while the addition of PSB improves performance, increases gross energy metabolizability, steers intestinal microbiota, and alters VFA concentrations in the intestine.
Article
Plant Sciences
Shuai Tang, Wei Liu, Qianqian Zhao, Kaidong Li, Jingyi Zhu, Wenbing Yao, Xiangdong Gao
Summary: The study found that co-administration of total polysaccharides from Astragalus membranaceus and Codonopsis pilosula could improve clinical symptoms, restore immune balance, and alleviate colonic mucosal damage in colitis mice. The unique efficacy of co-administration depended on the activation of the aryl hydrocarbon receptor (AhR) and upregulation of isovaleric acid and butyrate at specific doses.
JOURNAL OF ETHNOPHARMACOLOGY
(2021)
Review
Cell Biology
Dan Zhang, Yong-Ping Jian, Yu-Ning Zhang, Yao Li, Li-Ting Gu, Hui-Hui Sun, Ming-Di Liu, Hong-Lan Zhou, Yi-Shu Wang, Zhi-Xiang Xu
Summary: Short-chain fatty acids (SCFAs) are metabolites produced by bacterial fermentation of dietary fiber in the gut. They are absorbed by substrate transporters and play important roles in cellular metabolism. SCFAs are vital fuels for intestinal epithelial cells (IECs) and influence molecular processes such as blood glucose regulation and IEC function. They also affect intestinal motility, barrier function, and host metabolism, and play regulatory roles in local and peripheral metabolism. Major SCFAs like acetate, propionate, and butyrate are involved in immunity, apoptosis, inflammation, and lipid metabolism. This review highlights the diverse functional roles of SCFAs and their impact on intestines, metabolism, and diseases.
CELL COMMUNICATION AND SIGNALING
(2023)
Article
Fisheries
Fei Shi, Zhijie Lu, Minxuan Yang, Feng Li, Fanbin Zhan, Lijuan Zhao, Yanan Li, Qingqing Li, Jiangtao Li, Jun Li, Li Lin, Zhendong Qin
Summary: The study showed that APS can modulate the intestinal microbiota and activate the immune response to protect grass carp from bacterial infection.
Article
Agriculture, Dairy & Animal Science
Y. S. Liu, Y. Y. Zhang, J. L. Li, X. F. Wang, T. Xing, X. D. Zhu, L. Zhang, F. Gao
BRITISH POULTRY SCIENCE
(2020)
Article
Agriculture, Dairy & Animal Science
Xiaona Pan, Lin Zhang, Tong Xing, Jiaolong Li, Feng Gao
Summary: Wooden breast (WB) is a novel myopathy that affects modern broiler chickens, leading to muscle fiber degeneration and fibrosis, which in turn impairs meat quality and oxidative status. The WB group exhibited higher oxidative damage and mitochondrial dysfunction, along with elevated expression of Nrf2 pathway genes.
Article
Agriculture, Dairy & Animal Science
Yingying Zhang, Yingsen Liu, Jiaolong Li, Tong Xing, Yun Jiang, Lin Zhang, Feng Gao
ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES
(2020)
Article
Agriculture, Dairy & Animal Science
Y. S. Liu, Y. Y. Zhang, T. Xing, J. L. Li, X. F. Wang, X. D. Zhu, L. Zhang, F. Gao
BRITISH POULTRY SCIENCE
(2020)
Article
Agriculture, Dairy & Animal Science
Yingying Zhang, Yingsen Liu, Jiaolong Li, Tong Xing, Yun Jiang, Lin Zhang, Feng Gao
Article
Agriculture, Dairy & Animal Science
Bingbing Ma, Lin Zhang, Jiaolong Li, Tong Xing, Yun Jiang, Feng Gao
Summary: The study showed that heat stress negatively impacts the growth performance of broilers, altering body protein and amino acid metabolism. This leads to reduced muscle mass, decreased plasma amino acid levels, and increased activity of certain enzymes in the liver, affecting energy supply mechanisms in the body.
Article
Agriculture, Dairy & Animal Science
Q. Wang, X. F. Wang, T. Xing, J. L. Li, X. D. Zhu, L. Zhang, F. Gao
Summary: The combined use of XOS and IAPS has significant positive effects on the growth performance and intestinal mucosal barrier function of broiler chickens, improving daily weight gain and intestinal health.
Article
Agriculture, Dairy & Animal Science
T. Xing, Z. R. Zhao, X. Zhao, X. L. Xu, L. Zhang, F. Gao
Summary: Wooden breast myopathy in broiler chickens induces severe fibrosis in the pectoralis major muscle by enhancing extracellular matrix deposition, collagen cross-linking, and dysregulating TGF-beta signaling and the MMP and TIMP system.
Article
Physiology
Tong Xing, Xiaona Pan, Lin Zhang, Feng Gao
Summary: Wooden breast syndrome in broiler chickens not only affects the pectoralis major muscle but also leads to liver injury, as evidenced by higher plasma enzymes and histopathological changes in the liver. This myopathy induces oxidative stress, mitochondrial dysfunction, and hepatic apoptosis, along with inflammatory responses in the liver. Additional assessment is needed to understand the systemic physiological disparities and metabolic changes associated with wooden breast myopathy.
FRONTIERS IN PHYSIOLOGY
(2021)
Article
Nutrition & Dietetics
Ying-Ying Zhang, Ying-Sen Liu, Jiao-Long Li, Tong Xing, Yun Jiang, Lin Zhang, Feng Gao
Summary: This study found that dietary corn RS can improve immune function in broilers, as evidenced by increased relative weights of spleen, thymus, and bursa, as well as elevated concentrations of nitric oxide and interferon-gamma in plasma. Additionally, feeding 4% and 8% RS diets also increased the number of IgA-producing cells in the jejunum.
BRITISH JOURNAL OF NUTRITION
(2023)
Article
Agriculture, Dairy & Animal Science
B. B. Duan, J. W. Xu, T. Xing, J. L. Li, L. Zhang, F. Gao
Summary: This study aimed to evaluate the effects of dietary creatine nitrate (CrN) on the growth performance, meat quality, energy status, glycolysis, and gene expression in broilers. It was found that CrN had positive effects on muscle creatine concentration and energy status, and improved meat quality. Therefore, CrN may be a potential replacement for creatine supplementation.
Article
Agriculture, Dairy & Animal Science
Bingbing Ma, Tong Xing, Jiaolong Li, Lin Zhang, Yun Jiang, Feng Gao
Summary: This study investigated the mechanism of chronic heat stress-induced liver damage in broiler chickens. It found that chronic heat exposure caused liver microvesicular steatosis, vacuolar degeneration, and apoptosis in broilers. The study also observed increased liver relative weight, liver glutaminase activity, and plasma ammonia level in response to heat stress. Furthermore, heat stress enhanced the expression of endoplasmic reticulum stress response genes and apoptosis-related genes in the broiler liver.
Article
Agriculture, Dairy & Animal Science
Jiawen Xu, Tong Xing, Jiaolong Li, Lin Zhang, Feng Gao
Summary: CrN, a novel form of creatine, can improve meat quality by enhancing muscle creatine loading and delaying rapid glycolysis. This study demonstrated that dietary supplementation with CrN can attenuate energy expenditure and rapid muscle glycolysis induced by preslaughter transport.
JOURNAL OF ANIMAL SCIENCE
(2022)
Article
Agriculture, Dairy & Animal Science
Q. Wang, X. F. Wang, T. Xing, J. L. Li, X. D. Zhu, L. Zhang, F. Gao
Summary: The combination of XOS and IAPS can enhance intestinal mucosal immunity and barrier function in broilers by increasing cytokine gene expression, IgA-producing cell production, and modulating cecal microbiota. Additionally, the combination effect of XOS and IAPS is superior to the individual effects of CTC, XOS, or IAPS in the current study.
Article
Agriculture, Dairy & Animal Science
Jesper Tessin, Judith Rohde, Arne Jung, Nicole Kemper, Jochen Schulz
Summary: In this study, samples from poultry house environment and culled birds were collected, and E. cecorum was successfully isolated. The principle of isolating the pathogen by streaking on a chromogenic agar may motivate researchers to investigate transmission routes and optimize biosecurity measures.
Article
Agriculture, Dairy & Animal Science
Junqin Zhang, Zimin Xie, Yanlin Pan, Zuoxin Chen, Yunzhen Huang, Linlin Li, Jiawen Dong, Yong Xiang, Qi Zhai, Minhua Sun, Xingying Li, Shujian Huang, Ming Liao
Summary: In recent years, there has been an increase in the occurrence of fowl adenovirus 2 (FAdV-2) in China, posing a significant threat to the poultry industry. This study investigated the epidemiology, phylogenetic relationship, genomic characteristics, and pathogenicity of FAdV-2. The results showed that FAdV-2 was the most commonly detected serotype among various FAdV serotypes. Genetic analysis revealed that these FAdV-2 strains formed a distinct branch within the FAdV-D group and had a high nucleotide similarity with reference strains. Recombination analysis identified recombination events between FAdV-2 and FAdV-11 in some strains. Pathogenicity experiments demonstrated that a recombinant FAdV-2 strain caused a high mortality rate and more severe disease in chickens. These findings contribute to our understanding of FAdV-2 and provide a basis for vaccine development.
Article
Agriculture, Dairy & Animal Science
Ebtsam Iraqi, Ali Abdel Hady, Nadia Elsayed, Hanaa Khalil, Amina El-Saadany, Karim El-Sabrout
Summary: Thermal manipulation during egg incubation, particularly at 12 to 18 days, has positive effects on embryonic development, hatching characteristics, chick quality, as well as posthatch thermotolerance and performance.
Article
Agriculture, Dairy & Animal Science
Yong Liu, Mingxin Song, He Bai, Chunhua Wang, Fei Wang, Qi Yuan
Summary: Dietary curcumin supplementation can significantly improve egg quality of quails in the late laying period, primarily by improving lipid metabolism and selectively regulating the intestinal microbial community.
Article
Agriculture, Dairy & Animal Science
Lei Zhang, Zhixuan Song, Peiyao Li, Xingju Song, Xinming Tang, Dandan Hu
Summary: This study evaluated the vaccine potential of recombinant proteins for avian coccidiosis caused by Eimeria. The results showed that the rEten5-B protein can trigger immune protection against E. tenella and may be a potential and effective subunit vaccine for the control of coccidiosis in poultry.
Article
Agriculture, Dairy & Animal Science
Milan Kumar Sharma, Amit Kumar Singh, Doyun Goo, Venkata Sesha Reddy Choppa, Hanseo Ko, Hanyi Shi, Woo Kyun Kim
Summary: The study investigates the effect of Eimeria infection on gastrointestinal physiology, growth performance, and egg production of Hy-Line W-36 laying hens during peak production. Results show that Eimeria infection negatively affects body weight, feed intake, immune response, and nutrient transporter gene expression. Egg production temporarily ceases in hens infected with high and medium-high dosages of Eimeria.
Article
Agriculture, Dairy & Animal Science
Elwy A. Ashour, Mahmoud Kamal, Hayman A. A. Altaie, Ayman A. Swelum, Gamaleldin M. Suliman, Guillermo Tellez-Isaias, Mohamed E. Abd El-Hack
Summary: This study evaluated the effects of CP and ME on the performance and nutritional value of Japanese quail lay chicken. The results showed that protein and energy levels significantly influenced all productive outcomes except feed conversion ratio. The combination of dietary energy and protein levels had a substantial effect on all egg quality trials evaluated. It is recommended to feed layer Japanese quail between the ages of 8 and 20 weeks during the summer with a dietary energy content of 2,900 kcal ME/kg and 20% CP.
Article
Agriculture, Dairy & Animal Science
J. E. Doornweerd, R. F. Veerkamp, B. de Klerk, M. van der Sluis, A. C. Bouwman, E. D. Ellen, G. Kootstra
Summary: Tracking group-housed individual broilers using video can provide valuable information on their health, welfare, and performance. This study conducted a comprehensive analysis on broiler tracking on video and potential tracking errors, highlighting the potential and challenges of phenotyping broiler locomotion. The results emphasized the importance of addressing tracking errors, potential algorithm improvements, and the need for an external animal identification system for efficient locomotion phenotyping.
Article
Agriculture, Dairy & Animal Science
Jiayu Wu, Yanan Wang, Yu An, Changyu Tian, Lingfeng Wang, Zuhong Liu, Desheng Qi
Summary: This study compared the gene expression differences in liver tissues of laying hens at different ages using RNA sequencing, and found that the transport and metabolism of amino acids changed during the growing period, which influenced the growth and development of the hens.
Article
Agriculture, Dairy & Animal Science
J. Raabe, G. Raveendran, W. Otten, K. Homeyer, T. Bartels
Summary: This study investigated the effects of different flicker frequencies on the behavior, performance, and stress response in male turkeys. The results showed that flicker frequencies of 165 Hz or higher had no detrimental effect on growth performance, injurious pecking, or endocrine stress response in the turkeys.
Article
Agriculture, Dairy & Animal Science
Adamu Mani Isa, Yanyan Sun, Yuanmei Wang, Yunlei Li, Jingwei Yuan, Aixin Ni, Hui Ma, Lei Shi, Hailai Hagos Tesfay, Yunhe Zong, Panlin Wang, Pingzhuang Ge, Jilan Chen
Summary: This study sequenced mRNAs and lncRNAs in the ovary stroma of specific chicken breeds and their reciprocal crossbreds to understand the molecular mechanism of heterosis for egg production. Results showed that genes with nonadditive expression were related to follicle growth and atresia as well as oxidative stress in the crossbred hens.
Article
Agriculture, Dairy & Animal Science
Zhepeng Wang, Qiu Chen, Yiwei Wang, Yulu Wang, Ruifang Liu
Summary: The study investigates the functional variants associated with chicken eggshell color in the SLCO1B3 gene by measuring the eggshell color of Lueyang black-boned chickens and analyzing the genetic data. It identifies 15 variants in SLCO1B3 that are significantly associated with eggshell color. However, the functional analysis shows that one specific variant, 1B3_SNP108, does not have a significant effect on promoter activity. This study highlights the importance of SLCO1B3 and its variants in breeding eggshell color.
Article
Agriculture, Dairy & Animal Science
P. Yin, Q. Tong, B. M. Li, W. C. Zheng, Y. Wang, H. Q. Peng, X. L. Xue, S. Q. Wei
Summary: This study investigated the welfare and health of laying hens in a multitier system. The results showed that the spatial distribution of hens changed with increasing age, and lower-ranking hens preferred to stay in lower tiers to avoid competition but still had access to resources. This improved the welfare and health of the hens near the end of the laying cycle.
Article
Agriculture, Dairy & Animal Science
Wenwen Liang, Siqiong Jie, Yiqin Wang, Xiaowei Wen, Yanling Xiong, Xiaoxi Lin, Zhengrong Lv
Summary: This study examined the effect of risk perceptions on preventive behavior among vendors in the live poultry wholesale market and the live poultry retail market in Guangdong Province using the health belief model and structural equation modeling. The results showed that perceived severity and perceived benefits positively influenced vendors' self-efficacy in the wholesale market, while perceived barriers negatively affected self-efficacy in both the wholesale and retail markets. Moreover, cues to action mediated the relationship between perceived severity, perceived benefits, and self-efficacy, and also mediated the effect of perceived susceptibility among wholesale market vendors.
Article
Agriculture, Dairy & Animal Science
Shreeya Sharma, Raveendra R. Kulkarni, Shayan Sharif, Hosni Hassan, Mohammadali Alizadeh, Scott Pratt, Khaled Abdelaziz
Summary: The study investigates the impact of exposing chick embryos to antigens via in ovo delivery of poultry-specific lactobacilli on the expression of genes associated with early bursal development and maturation. Results indicate that the supplementation of poultry-specific lactobacilli to chick embryos can accelerate the development and immunological maturation of the bursa of Fabricius.
