标题
Self-amplifying RNA vaccines for infectious diseases
作者
关键词
-
出版物
GENE THERAPY
Volume -, Issue -, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2020-10-23
DOI
10.1038/s41434-020-00204-y
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Multivalent Peptide-functionalized Bioreducible Polymers for Cellular Delivery of Various RNAs
- (2020) Dong-Chu Yang et al. BIOMACROMOLECULES
- Innovations in HIV-1 Vaccine Design
- (2020) Letitia D. Jones et al. CLINICAL THERAPEUTICS
- Plant-made HIV vaccines and potential candidates
- (2020) Jocelyne Tremouillaux-Guiller et al. CURRENT OPINION IN BIOTECHNOLOGY
- Immune Responses to Viral Gene Therapy Vectors
- (2020) Jamie L. Shirley et al. MOLECULAR THERAPY
- Synthesis of low immunogenicity RNA with high-temperature in vitro transcription
- (2020) Monica Z. Wu et al. RNA
- Opportunities and Challenges in the Delivery of mRNA-Based Vaccines
- (2020) Abishek Wadhwa et al. Pharmaceutics
- The promise of mRNA vaccines: a biotech and industrial perspective
- (2020) Nicholas A. C. Jackson et al. npj Vaccines
- Big Is Beautiful: Enhanced saRNA Delivery and Immunogenicity by a Higher Molecular Weight, Bioreducible, Cationic Polymer
- (2020) Anna K. Blakney et al. ACS Nano
- Mannosylated Poly(ethylene imine) Copolymers Enhance saRNA Uptake and Expression in Human Skin Explants
- (2020) Anna K. Blakney et al. BIOMACROMOLECULES
- RNA therapeutics on the rise
- (2020) Feng Wang et al. NATURE REVIEWS DRUG DISCOVERY
- Assessing the impact of AGS-004, a dendritic cell-based immunotherapy, and vorinostat on persistent HIV-1 Infection
- (2020) Cynthia L. Gay et al. Scientific Reports
- Investigating the Impact of Delivery System Design on the Efficacy of Self-Amplifying RNA Vaccines
- (2020) Giulia Anderluzzi et al. Vaccines
- Evaluation of the mRNA-1273 Vaccine against SARS-CoV-2 in Nonhuman Primates
- (2020) Kizzmekia S. Corbett et al. NEW ENGLAND JOURNAL OF MEDICINE
- An mRNA Vaccine against SARS-CoV-2 — Preliminary Report
- (2020) Lisa A. Jackson et al. NEW ENGLAND JOURNAL OF MEDICINE
- Nonclinical safety assessment of repeated administration and biodistribution of a novel rabies self-amplifying mRNA vaccine in rats
- (2020) Alan Stokes et al. REGULATORY TOXICOLOGY AND PHARMACOLOGY
- Self-amplifying RNA SARS-CoV-2 lipid nanoparticle vaccine candidate induces high neutralizing antibody titers in mice
- (2020) Paul F. McKay et al. Nature Communications
- Self-Amplifying RNA Vaccines for Venezuelan Equine Encephalitis Virus Induce Robust Protective Immunogenicity in Mice
- (2019) Marcelo M. Samsa et al. MOLECULAR THERAPY
- Characterization of HIV-1 nucleoside-modified mRNA vaccines in rabbits and rhesus macaques
- (2019) Norbert Pardi et al. Molecular Therapy-Nucleic Acids
- mRNA as a Transformative Technology for Vaccine Development to Control Infectious Diseases
- (2019) Giulietta Maruggi et al. MOLECULAR THERAPY
- Delivering the Messenger: Advances in Technologies for Therapeutic mRNA Delivery
- (2019) Piotr S. Kowalski et al. MOLECULAR THERAPY
- RNA Epitranscriptome: Role of the 5' Cap
- (2019) Anton P. McCaffrey Genetic Engineering & Biotechnology News
- Inside out: optimization of lipid nanoparticle formulations for exterior complexation and in vivo delivery of saRNA
- (2019) Anna K. Blakney et al. GENE THERAPY
- Effects of cationic adjuvant formulation particle type, fluidity and immunomodulators on delivery and immunogenicity of saRNA
- (2019) Anna K. Blakney et al. JOURNAL OF CONTROLLED RELEASE
- Co-administration of GM-CSF expressing RNA is a powerful tool to enhance potency of SAM-based vaccines
- (2019) Cristina Manara et al. VACCINE
- In vitro evolution of enhanced RNA replicons for immunotherapy
- (2019) Yingzhong Li et al. Scientific Reports
- Neutral lipopolyplexes for in vivo delivery of conventional and replicative RNA vaccine
- (2019) Federico Perche et al. Molecular Therapy-Nucleic Acids
- Mannosylation of LNP Results in Improved Potency for Self-Amplifying RNA (SAM) Vaccines
- (2019) Roshan Goswami et al. ACS Infectious Diseases
- Immunogenicity of RNA Replicons Encoding HIV Env Immunogens Designed for Self-Assembly into Nanoparticles
- (2019) Mariane Melo et al. MOLECULAR THERAPY
- A trans-amplifying RNA vaccine strategy for induction of potent protective immunity
- (2019) Tim Beissert et al. MOLECULAR THERAPY
- Delivery of mRNA vaccines with heterocyclic lipids increases anti-tumor efficacy by STING-mediated immune cell activation
- (2019) Lei Miao et al. NATURE BIOTECHNOLOGY
- Efficient inhibition of RNA self-primed extension by addition of competing 3′-capture DNA-improved RNA synthesis by T7 RNA polymerase
- (2019) Yasaman Gholamalipour et al. NUCLEIC ACIDS RESEARCH
- Expression Kinetics and Innate Immune Response after Electroporation and LNP-Mediated Delivery of a Self-Amplifying mRNA in the Skin
- (2019) Hanne Huysmans et al. Molecular Therapy-Nucleic Acids
- Immunogenicity and Protection Efficacy of a Naked Self-Replicating mRNA-Based Zika Virus Vaccine
- (2019) Zifu Zhong et al. Vaccines
- Advances in RNA Vaccines for Preventive Indications: A Case Study of A Vaccine Against Rabies
- (2019) Armbruster et al. Vaccines
- Messenger RNA translation enhancement by immune evasion proteins: a comparative study between EKB (vaccinia virus) and NS1 (influenza A virus)
- (2019) Yi Liu et al. Scientific Reports
- Therapeutic Vaccine in Chronically HIV-1-Infected Patients: A Randomized, Double-Blind, Placebo-Controlled Phase IIa Trial with HTI-TriMix
- (2019) Wesley de Jong et al. Vaccines
- Immunogenicity of AGS-004 Dendritic Cell Therapy in Patients Treated During Acute HIV Infection
- (2018) Cynthia L. Gay et al. AIDS RESEARCH AND HUMAN RETROVIRUSES
- The Neutralizing Antibody Response to the HIV-1 Env Protein
- (2018) Penny L. Moore CURRENT HIV RESEARCH
- HIV-1 Vaccines Based on Antibody Identification, B Cell Ontogeny, and Epitope Structure
- (2018) Peter D. Kwong et al. IMMUNITY
- Nucleoside-modified mRNA vaccines induce potent T follicular helper and germinal center B cell responses
- (2018) Norbert Pardi et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Self-Amplifying RNA Vaccines Give Equivalent Protection against Influenza to mRNA Vaccines but at Much Lower Doses
- (2018) Annette B. Vogel et al. MOLECULAR THERAPY
- mRNA vaccines — a new era in vaccinology
- (2018) Norbert Pardi et al. NATURE REVIEWS DRUG DISCOVERY
- Innate immune control of alphavirus infection
- (2018) Kathryn S Carpentier et al. Current Opinion in Virology
- Self-Amplifying Replicon RNA Delivery to Dendritic Cells by Cationic Lipids
- (2018) Pavlos C. Englezou et al. Molecular Therapy-Nucleic Acids
- Uridine Depletion and Chemical Modification Increase Cas9 mRNA Activity and Reduce Immunogenicity without HPLC Purification
- (2018) Sriram Vaidyanathan et al. Molecular Therapy-Nucleic Acids
- A Nanostructured Lipid Carrier for Delivery of a Replicating Viral RNA Provides Single, Low-Dose Protection against Zika
- (2018) Jesse H. Erasmus et al. MOLECULAR THERAPY
- Engineering multi-specific antibodies against HIV-1
- (2018) Neal N. Padte et al. Retrovirology
- Phase I clinical trial of an intranodally administered mRNA based therapeutic vaccine against HIV-1 infection
- (2018) Lorna Leal et al. AIDS
- DNA Vaccines—How Far From Clinical Use?
- (2018) Dominika Hobernik et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Self-Replicating RNA Viruses for RNA Therapeutics
- (2018) Kenneth Lundstrom MOLECULES
- Recent progress in broadly neutralizing antibodies to HIV
- (2018) Devin Sok et al. NATURE IMMUNOLOGY
- Adeno-associated virus gene delivery of broadly neutralizing antibodies as prevention and therapy against HIV-1
- (2018) Allen Lin et al. Retrovirology
- Efficient Induction of T Cells against Conserved HIV-1 Regions by Mosaic Vaccines Delivered as Self-Amplifying mRNA
- (2018) Nathifa Moyo et al. Molecular Therapy-Methods & Clinical Development
- Influenza Vaccines: Good, But We Can Do Better
- (2018) Catharine I Paules et al. JOURNAL OF INFECTIOUS DISEASES
- Nanotechnologies in delivery of mRNA therapeutics using nonviral vector-based delivery systems
- (2017) S Guan et al. GENE THERAPY
- Improvement of In Vivo Expression of Genes Delivered by Self-Amplifying RNA Using Vaccinia Virus Immune Evasion Proteins
- (2017) Tim Beissert et al. HUMAN GENE THERAPY
- Polyvalent vaccine approaches to combat HIV-1 diversity
- (2017) Bette Korber et al. IMMUNOLOGICAL REVIEWS
- Self-replicating RNA vaccine functionality modulated by fine-tuning of polyplex delivery vehicle structure
- (2017) Thomas Démoulins et al. JOURNAL OF CONTROLLED RELEASE
- Induction of an IFN-Mediated Antiviral Response by a Self-Amplifying RNA Vaccine: Implications for Vaccine Design
- (2017) Timothy Pepini et al. JOURNAL OF IMMUNOLOGY
- Simply put: Vaccination saves lives
- (2017) Walter A. Orenstein et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Immunogenicity and protective efficacy induced by self-amplifying mRNA vaccines encoding bacterial antigens
- (2017) Giulietta Maruggi et al. VACCINE
- Administration of nucleoside-modified mRNA encoding broadly neutralizing antibody protects humanized mice from HIV-1 challenge
- (2017) Norbert Pardi et al. Nature Communications
- Engineering antibody-like inhibitors to prevent and treat HIV-1 infection
- (2017) Matthew R. Gardner et al. Current Opinion in HIV and AIDS
- An RNA nanoparticle vaccine against Zika virus elicits antibody and CD8+ T cell responses in a mouse model
- (2017) Jasdave S. Chahal et al. Scientific Reports
- Designing liposomal adjuvants for the next generation of vaccines
- (2016) Yvonne Perrie et al. ADVANCED DRUG DELIVERY REVIEWS
- Efficacy and immunogenicity of unmodified and pseudouridine-modified mRNA delivered systemically with lipid nanoparticles in vivo
- (2016) Kevin J. Kauffman et al. BIOMATERIALS
- Immunization of HIV-1-Infected Persons With Autologous Dendritic Cells Transfected With mRNA Encoding HIV-1 Gag and Nef
- (2016) Rajesh T. Gandhi et al. JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
- Dendritic Cell Immunotherapy for HIV-1 Infection Using Autologous HIV-1 RNA
- (2016) Jeffrey M. Jacobson et al. JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
- Reversible methylation of m6Am in the 5′ cap controls mRNA stability
- (2016) Jan Mauer et al. NATURE
- An RNA trapping mechanism in Alphavirus mRNA promotes ribosome stalling and translation initiation
- (2016) René Toribio et al. NUCLEIC ACIDS RESEARCH
- Self-Amplifying mRNA Vaccines Expressing Multiple Conserved Influenza Antigens Confer Protection against Homologous and Heterosubtypic Viral Challenge
- (2016) Diletta Magini et al. PLoS One
- Dendrimer-RNA nanoparticles generate protective immunity against lethal Ebola, H1N1 influenza, andToxoplasma gondiichallenges with a single dose
- (2016) Jasdave S. Chahal et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- CD8 T-cell priming upon mRNA vaccination is restricted to bone-marrow-derived antigen-presenting cells and may involve antigen transfer from myocytes
- (2015) Sandra Lazzaro et al. IMMUNOLOGY
- A novel RNA-based adjuvant combines strong immunostimulatory capacities with a favorable safety profile
- (2015) Regina Heidenreich et al. INTERNATIONAL JOURNAL OF CANCER
- N 1 -methylpseudouridine-incorporated mRNA outperforms pseudouridine-incorporated mRNA by providing enhanced protein expression and reduced immunogenicity in mammalian cell lines and mice
- (2015) Oliwia Andries et al. JOURNAL OF CONTROLLED RELEASE
- Induction of Broad-Based Immunity and Protective Efficacy by Self-amplifying mRNA Vaccines Encoding Influenza Virus Hemagglutinin
- (2015) Michela Brazzoli et al. JOURNAL OF VIROLOGY
- Sequence-engineered mRNA Without Chemical Nucleoside Modifications Enables an Effective Protein Therapy in Large Animals
- (2015) Andreas Thess et al. MOLECULAR THERAPY
- The 5′ and 3′ ends of alphavirus RNAs – Non-coding is not non-functional
- (2015) Jennifer L. Hyde et al. VIRUS RESEARCH
- IFIT1 Differentially Interferes with Translation and Replication of Alphavirus Genomes and Promotes Induction of Type I Interferon
- (2015) Josephine M. Reynaud et al. PLoS Pathogens
- Potent Immune Responses in Rhesus Macaques Induced by Nonviral Delivery of a Self-amplifying RNA Vaccine Expressing HIV Type 1 Envelope With a Cationic Nanoemulsion
- (2014) W. M. Bogers et al. JOURNAL OF INFECTIOUS DISEASES
- A Cationic Nanoemulsion for the Delivery of Next-generation RNA Vaccines
- (2014) Luis A Brito et al. MOLECULAR THERAPY
- A Viral RNA Structural Element Alters Host Recognition of Nonself RNA
- (2014) J. L. Hyde et al. SCIENCE
- Self-replicating Replicon-RNA Delivery to Dendritic Cells by Chitosan-nanoparticles for Translation In Vitro and In Vivo
- (2014) Kenneth C McCullough et al. Molecular Therapy-Nucleic Acids
- Efficient Generation of Human iPSCs by a Synthetic Self-Replicative RNA
- (2013) Naohisa Yoshioka et al. Cell Stem Cell
- RNA viruses can hijack vertebrate microRNAs to suppress innate immunity
- (2013) Derek W. Trobaugh et al. NATURE
- Key roles of adjuvants in modern vaccines
- (2013) Steven G Reed et al. NATURE MEDICINE
- A brief history of the global effort to develop a preventive HIV vaccine
- (2013) José Esparza VACCINE
- A novel, disruptive vaccination technology
- (2013) Karl-Josef Kallen et al. Human Vaccines & Immunotherapeutics
- Rapidly produced SAM® vaccine against H7N9 influenza is immunogenic in mice
- (2013) Armin Hekele et al. Emerging Microbes & Infections
- Variation between Populations in the Innate Immune Response to Vaccine Adjuvants
- (2013) Tobias R. Kollmann Frontiers in Immunology
- Type I IFN Counteracts the Induction of Antigen-Specific Immune Responses by Lipid-Based Delivery of mRNA Vaccines
- (2012) Charlotte Pollard et al. MOLECULAR THERAPY
- Immune-Correlates Analysis of an HIV-1 Vaccine Efficacy Trial
- (2012) Barton F. Haynes et al. NEW ENGLAND JOURNAL OF MEDICINE
- Nonviral delivery of self-amplifying RNA vaccines
- (2012) A. J. Geall et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- mRNA-based dendritic cell vaccination induces potent antiviral T-cell responses in HIV-1-infected patients
- (2011) Ellen Van Gulck et al. AIDS
- A phase I/IIa immunotherapy trial of HIV-1-infected patients with Tat, Rev and Nef expressing dendritic cells followed by treatment interruption
- (2011) Sabine D. Allard et al. CLINICAL IMMUNOLOGY
- Assembly of Alphavirus Replication Complexes from RNA and Protein Components in a Novel trans-Replication System in Mammalian Cells
- (2011) P. Spuul et al. JOURNAL OF VIROLOGY
- Generating the optimal mRNA for therapy: HPLC purification eliminates immune activation and improves translation of nucleoside-modified, protein-encoding mRNA
- (2011) Katalin Karikó et al. NUCLEIC ACIDS RESEARCH
- Phosphorothioate cap analogs increase stability and translational efficiency of RNA vaccines in immature dendritic cells and induce superior immune responses in vivo
- (2010) A N Kuhn et al. GENE THERAPY
- 2′-O methylation of the viral mRNA cap evades host restriction by IFIT family members
- (2010) Stephane Daffis et al. NATURE
- Immunologic activity and safety of autologous HIV RNA-electroporated dendritic cells in HIV-1 infected patients receiving antiretroviral therapy
- (2009) Jean-Pierre Routy et al. CLINICAL IMMUNOLOGY
- Incorporation of Pseudouridine Into mRNA Yields Superior Nonimmunogenic Vector With Increased Translational Capacity and Biological Stability
- (2008) Katalin Karikó et al. MOLECULAR THERAPY
- DNA vaccines: ready for prime time?
- (2008) Michele A. Kutzler et al. NATURE REVIEWS GENETICS
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