标题
Key roles of adjuvants in modern vaccines
作者
关键词
-
出版物
NATURE MEDICINE
Volume 19, Issue 12, Pages 1597-1608
出版商
Springer Nature
发表日期
2013-12-06
DOI
10.1038/nm.3409
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- The Adjuvants Aluminum Hydroxide and MF59 Induce Monocyte and Granulocyte Chemoattractants and Enhance Monocyte Differentiation toward Dendritic Cells
- (2014) A. Seubert et al. JOURNAL OF IMMUNOLOGY
- Selection of an adjuvant for seasonal influenza vaccine in elderly people: modelling immunogenicity from a randomized trial
- (2013) Hans C Rümke et al. BMC INFECTIOUS DISEASES
- MyD88 and TRIF synergistic interaction is required for TH1-cell polarization with a synthetic TLR4 agonist adjuvant
- (2013) Mark T. Orr et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Enhancing immunogenicity of a 3′aminomethylnicotine-DT-conjugate anti-nicotine vaccine with CpG adjuvant in mice and non-human primates
- (2013) Michael J. McCluskie et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Implications of narcolepsy link with swine-influenza vaccine
- (2013) Kelly Morris LANCET INFECTIOUS DISEASES
- Increased childhood incidence of narcolepsy in western Sweden after H1N1 influenza vaccination
- (2013) A. Szakacs et al. NEUROLOGY
- A Randomized, Observer-Blinded Immunogenicity Trial of Cervarix® and Gardasil® Human Papillomavirus Vaccines in 12-15 Year Old Girls
- (2013) Eve Draper et al. PLoS One
- Incidence of narcolepsy in Norwegian children and adolescents after vaccination against H1N1 influenza A
- (2013) M.S. Heier et al. SLEEP MEDICINE
- Risk of narcolepsy in children and young people receiving AS03 adjuvanted pandemic A/H1N1 2009 influenza vaccine: retrospective analysis
- (2013) E. Miller et al. BMJ-British Medical Journal
- The potential of 1018 ISS adjuvant in hepatitis B vaccines
- (2013) Nelson F Eng et al. Human Vaccines & Immunotherapeutics
- Distinct TLR adjuvants differentially stimulate systemic and local innate immune responses in nonhuman primates
- (2012) M. Kwissa et al. BLOOD
- Technologies for enhanced efficacy of DNA vaccines
- (2012) Fadi Saade et al. Expert Review of Vaccines
- The mycobacterial cord factor adjuvant analogue trehalose-6,6′-dibehenate (TDB) activates the Nlrp3 inflammasome
- (2012) Katrin Schweneker et al. IMMUNOBIOLOGY
- Alum increases antigen uptake, reduces antigen degradation and sustains antigen presentation by DCs in vitro
- (2012) Tirth R. Ghimire et al. IMMUNOLOGY LETTERS
- MF59 formulated with CpG ODN as a potent adjuvant of recombinant HSP65-MUC1 for inducing anti-MUC1+ tumor immunity in mice
- (2012) Ming Yang et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- A Comparative Study of Stress-mediated Immunological Functions with the Adjuvanticity of Alum
- (2012) Yufei Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Importance of Adjuvant Formulation in the Development of a Tuberculosis Vaccine
- (2012) S. L. Baldwin et al. JOURNAL OF IMMUNOLOGY
- MF59 and Pam3CSK4 Boost Adaptive Responses to Influenza Subunit Vaccine through an IFN Type I-Independent Mechanism of Action
- (2012) E. Caproni et al. JOURNAL OF IMMUNOLOGY
- Type II NKT cells facilitate Alum-sensing and humoral immunity
- (2012) Hemangi B. Shah et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Pre-existing immunity against vaccine vectors - friend or foe?
- (2012) M. Saxena et al. MICROBIOLOGY-SGM
- A Phase 3 Trial of RTS,S/AS01 Malaria Vaccine in African Infants
- (2012) NEW ENGLAND JOURNAL OF MEDICINE
- Increased Incidence and Clinical Picture of Childhood Narcolepsy following the 2009 H1N1 Pandemic Vaccination Campaign in Finland
- (2012) Markku Partinen et al. PLoS One
- AS03 Adjuvanted AH1N1 Vaccine Associated with an Abrupt Increase in the Incidence of Childhood Narcolepsy in Finland
- (2012) Hanna Nohynek et al. PLoS One
- Selective TRIF-Dependent Signaling by a Synthetic Toll-Like Receptor 4 Agonist
- (2012) W. S. Bowen et al. Science Signaling
- Demonstration of safety and enhanced seroprotection against hepatitis B with investigational HBsAg-1018 ISS vaccine compared to a licensed hepatitis B vaccine
- (2012) Benjamin P. Sablan et al. VACCINE
- The mechanism of action of MF59 – An innately attractive adjuvant formulation
- (2012) D.T. O’Hagan et al. VACCINE
- Improved CD4+ T cell responses to Mycobacterium tuberculosis in PPD-negative adults by M72/AS01 as compared to the M72/AS02 and Mtb72F/AS02 tuberculosis candidate vaccine formulations: A randomized trial
- (2012) Isabel Leroux-Roels et al. VACCINE
- MF59 oil-in-water emulsion in combination with a synthetic TLR4 agonist (E6020) is a potent adjuvant for a combination Meningococcus vaccine
- (2012) Manmohan Singh et al. Human Vaccines & Immunotherapeutics
- The role of the lymphatic system in vaccine trafficking and immune response
- (2011) Ivy Pal et al. ADVANCED DRUG DELIVERY REVIEWS
- Narcolepsy onset is seasonal and increased following the 2009 H1N1 pandemic in china
- (2011) Fang Han et al. ANNALS OF NEUROLOGY
- The effect of micro and nanotopography on endocytosis in drug and gene delivery systems
- (2011) Benjamin K.K. Teo et al. BIOMATERIALS
- Influenza virosomes as a vaccine adjuvant and carrier system
- (2011) Christian Moser et al. Expert Review of Vaccines
- Adjuvant effect of cationic liposomes and CpG depends on administration route
- (2011) Bram Slütter et al. JOURNAL OF CONTROLLED RELEASE
- The vesicle size of DDA:TDB liposomal adjuvants plays a role in the cell-mediated immune response but has no significant effect on antibody production
- (2011) Malou Henriksen-Lacey et al. JOURNAL OF CONTROLLED RELEASE
- Alum adjuvant: some of the tricks of the oldest adjuvant
- (2011) M. Kool et al. JOURNAL OF MEDICAL MICROBIOLOGY
- Negatively Charged Liposomes Show Potent Adjuvant Activity When Simply Admixed with Protein Antigens
- (2011) Nijaporn Yanasarn et al. MOLECULAR PHARMACEUTICS
- Chitosan Microparticles and Nanoparticles as Biocompatible Delivery Vehicles for Peptide and Protein-Based Immunocontraceptive Vaccines
- (2011) Brendon Y. Chua et al. MOLECULAR PHARMACEUTICS
- Programming the magnitude and persistence of antibody responses with innate immunity
- (2011) Sudhir Pai Kasturi et al. NATURE
- Systems biology of vaccination for seasonal influenza in humans
- (2011) Helder I Nakaya et al. NATURE IMMUNOLOGY
- Alum's adjuvant action: grease is the word
- (2011) M Lamine Mbow et al. NATURE MEDICINE
- DNA released from dying host cells mediates aluminum adjuvant activity
- (2011) Thomas Marichal et al. NATURE MEDICINE
- Alum interaction with dendritic cell membrane lipids is essential for its adjuvanticity
- (2011) Tracy L Flach et al. NATURE MEDICINE
- Eliciting Mucosal Immunity
- (2011) Wayne I. Lencer et al. NEW ENGLAND JOURNAL OF MEDICINE
- First Results of Phase 3 Trial of RTS,S/AS01 Malaria Vaccine in African Children
- (2011) NEW ENGLAND JOURNAL OF MEDICINE
- Adjuvanticity of the oil-in-water emulsion MF59 is independent of Nlrp3 inflammasome but requires the adaptor protein MyD88
- (2011) A. Seubert et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Inflammasome-independent role of the apoptosis-associated speck-like protein containing CARD (ASC) in the adjuvant effect of MF59
- (2011) A. H. Ellebedy et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Quantitative proteomics analysis of adsorbed plasma proteins classifies nanoparticles with different surface properties and size
- (2011) Haizhen Zhang et al. PROTEOMICS
- Explorations of clinical trials and pharmacovigilance databases of MF59®-adjuvanted influenza vaccines for associated cases of narcolepsy
- (2011) Theodore F. Tsai et al. SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES
- MF59 Adjuvant Enhances Diversity and Affinity of Antibody-Mediated Immune Response to Pandemic Influenza Vaccines
- (2011) S. Khurana et al. Science Translational Medicine
- Targeting TLRs Expands the Antibody Repertoire in Response to a Malaria Vaccine
- (2011) S. R. Wiley et al. Science Translational Medicine
- Targeting human dendritic cell subsets for improved vaccines
- (2011) Hideki Ueno et al. SEMINARS IN IMMUNOLOGY
- Vaccine adjuvants alum and MF59 induce rapid recruitment of neutrophils and monocytes that participate in antigen transport to draining lymph nodes
- (2011) Samuele Calabro et al. VACCINE
- Adjuvant System AS03 containing α-tocopherol modulates innate immune response and leads to improved adaptive immunity
- (2011) Sandra Morel et al. VACCINE
- Immunomodulatory and physical effects of oil composition in vaccine adjuvant emulsions
- (2011) Christopher B. Fox et al. VACCINE
- Vaccine adjuvant activity of 3M-052: An imidazoquinoline designed for local activity without systemic cytokine induction
- (2011) Dmitri Smirnov et al. VACCINE
- Amphiphilic Poly(Amino Acid) Nanoparticles Induce Size-Dependent Dendritic Cell Maturation
- (2010) Hyungjin Kim et al. ADVANCED FUNCTIONAL MATERIALS
- Cross-priming CD8+ T cells by targeting antigens to human dendritic cells through DCIR
- (2010) E. Klechevsky et al. BLOOD
- Antibody Response to Polyhistidine-Tagged Peptide and Protein Antigens Attached to Liposomes via Lipid-Linked Nitrilotriacetic Acid in Mice
- (2010) Douglas S. Watson et al. Clinical and Vaccine Immunology
- Relationship between the size of nanoparticles and their adjuvant activity: Data from a study with an improved experimental design
- (2010) Xinran Li et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Nano-microparticles as immune adjuvants: correlating particle sizes and the resultant immune responses
- (2010) Moses O Oyewumi et al. Expert Review of Vaccines
- Administration routes affect the quality of immune responses: A cross-sectional evaluation of particulate antigen-delivery systems
- (2010) Deepa Mohanan et al. JOURNAL OF CONTROLLED RELEASE
- Liposomal cationic charge and antigen adsorption are important properties for the efficient deposition of antigen at the injection site and ability of the vaccine to induce a CMI response
- (2010) Malou Henriksen-Lacey et al. JOURNAL OF CONTROLLED RELEASE
- Polymer particle shape independently influences binding and internalization by macrophages
- (2010) Gaurav Sharma et al. JOURNAL OF CONTROLLED RELEASE
- Human CD141+(BDCA-3)+dendritic cells (DCs) represent a unique myeloid DC subset that cross-presents necrotic cell antigens
- (2010) Sarah L. Jongbloed et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Superior antigen cross-presentation and XCR1 expression define human CD11c+CD141+cells as homologues of mouse CD8+dendritic cells
- (2010) Annabell Bachem et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Cutting Edge: Mincle Is Essential for Recognition and Adjuvanticity of the Mycobacterial Cord Factor and its Synthetic Analog Trehalose-Dibehenate
- (2010) H. Schoenen et al. JOURNAL OF IMMUNOLOGY
- Expression of Genes Associated with Immunoproteasome Processing of Major Histocompatibility Complex Peptides Is Indicative of Protection with Adjuvanted RTS,S Malaria Vaccine
- (2010) Maryanne T. Vahey et al. JOURNAL OF INFECTIOUS DISEASES
- Toxicity and cellular uptake of gold nanoparticles: what we have learned so far?
- (2010) Alaaldin M. Alkilany et al. JOURNAL OF NANOPARTICLE RESEARCH
- Vaccines with Aluminum-containing Adjuvants: Optimizing Vaccine Efficacy and Thermal Stability
- (2010) Tanya Clapp et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- What the Cell “Sees” in Bionanoscience
- (2010) Dorota Walczyk et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Increased potency of an inactivated trivalent polio vaccine with oil-in-water emulsions
- (2010) Susan L. Baldwin et al. VACCINE
- Alum Induces Innate Immune Responses through Macrophage and Mast Cell Sensors, But These Sensors Are Not Required for Alum to Act As an Adjuvant for Specific Immunity
- (2009) A. S. McKee et al. JOURNAL OF IMMUNOLOGY
- AS04, an Aluminum Salt- and TLR4 Agonist-Based Adjuvant System, Induces a Transient Localized Innate Immune Response Leading to Enhanced Adaptive Immunity
- (2009) A. M. Didierlaurent et al. JOURNAL OF IMMUNOLOGY
- Randomized, Double‐Blind, Phase 2a Trial of Falciparum Malaria Vaccines RTS,S/AS01B and RTS,S/AS02A in Malaria‐Naive Adults: Safety, Efficacy, and Immunologic Associates of Protection
- (2009) Kent E. Kester et al. JOURNAL OF INFECTIOUS DISEASES
- In VivoStudies on the Effect of Co-Encapsulation of CpG DNA and Antigen in Acid-Degradable Microparticle Vaccines
- (2009) Tristan T. Beaudette et al. MOLECULAR PHARMACEUTICS
- Materials engineering for immunomodulation
- (2009) Jeffrey A. Hubbell et al. NATURE
- MF59 Emulsion Is an Effective Delivery System for a Synthetic TLR4 Agonist (E6020)
- (2009) Barbara C. Baudner et al. PHARMACEUTICAL RESEARCH
- Evaluation of RTS,S/AS02A and RTS,S/AS01B in Adults in a High Malaria Transmission Area
- (2009) Mark E. Polhemus et al. PLoS One
- Randomized Controlled Trial of RTS,S/AS02D and RTS,S/AS01E Malaria Candidate Vaccines Given According to Different Schedules in Ghanaian Children
- (2009) Seth Owusu-Agyei et al. PLoS One
- Fast rise of broadly cross-reactive antibodies after boosting long-lived human memory B cells primed by an MF59 adjuvanted prepandemic vaccine
- (2009) G. Galli et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Optimized subunit vaccine protects against experimental leishmaniasis
- (2009) Sylvie Bertholet et al. VACCINE
- Mechanism of action of licensed vaccine adjuvants
- (2009) Elaine Tritto et al. VACCINE
- Accessing the therapeutic potential of immunostimulatory nucleic acids
- (2008) Winfried Barchet et al. CURRENT OPINION IN IMMUNOLOGY
- Alum adjuvanticity: Unraveling a century old mystery
- (2008) Ennio De Gregorio et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- The Nlrp3 inflammasome is critical for aluminium hydroxide-mediated IL-1β secretion but dispensable for adjuvant activity
- (2008) Luigi Franchi et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Functional Specializations of Human Epidermal Langerhans Cells and CD14+ Dermal Dendritic Cells
- (2008) Eynav Klechevsky et al. IMMUNITY
- Differential Activation of Human and Mouse Toll-Like Receptor 4 by the Adjuvant Candidate LpxL1 of Neisseria meningitidis
- (2008) L. Steeghs et al. INFECTION AND IMMUNITY
- Alum adjuvant boosts adaptive immunity by inducing uric acid and activating inflammatory dendritic cells
- (2008) Mirjam Kool et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Pivotal Advance: Eosinophils mediate early alum adjuvant-elicited B cell priming and IgM production
- (2008) H.-B. Wang et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants
- (2008) Stephanie C. Eisenbarth et al. NATURE
- Direct proteasome-independent cross-presentation of viral antigen by plasmacytoid dendritic cells on major histocompatibility complex class I
- (2008) Tiziana Di Pucchio et al. NATURE IMMUNOLOGY
- Systems biology approach predicts immunogenicity of the yellow fever vaccine in humans
- (2008) Troy D Querec et al. NATURE IMMUNOLOGY
- Molecular and cellular signatures of human vaccine adjuvants
- (2008) F. Mosca et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Combination adjuvants for the induction of potent, long-lasting antibody and T-cell responses to influenza vaccine in mice
- (2008) Andreas Wack et al. VACCINE
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