IFIT1 Differentially Interferes with Translation and Replication of Alphavirus Genomes and Promotes Induction of Type I Interferon

IFIT1: A dual sensor and effector molecule that detects non-2′-O methylated viral RNA and inhibits its translation

(2014) Michael S. Diamond   CYTOKINE & GROWTH FACTOR REVIEWS

Eilat Virus Host Range Restriction Is Present at Multiple Levels of the Virus Life Cycle

(2014) Farooq Nasar et al.   JOURNAL OF VIROLOGY

A Viral RNA Structural Element Alters Host Recognition of Nonself RNA

(2014) J. L. Hyde et al.   SCIENCE

The Antiviral Activities of ISG15

(2013) David J. Morales et al.   JOURNAL OF MOLECULAR BIOLOGY

Encapsidation of Host-Derived Factors Correlates with Enhanced Infectivity of Sindbis Virus

(2013) K. J. Sokoloski et al.   JOURNAL OF VIROLOGY

Interferon-Stimulated Poly(ADP-Ribose) Polymerases Are Potent Inhibitors of Cellular Translation and Virus Replication

(2013) S. Atasheva et al.   JOURNAL OF VIROLOGY

The Amino-Terminal Domain of Alphavirus Capsid Protein Is Dispensable for Viral Particle Assembly but Regulates RNA Encapsidation through Cooperative Functions of Its Subdomains

(2013) V. Lulla et al.   JOURNAL OF VIROLOGY

Structural basis for viral 5′-PPP-RNA recognition by human IFIT proteins

(2013) Yazan M. Abbas et al.   NATURE

Inhibition of translation by IFIT family members is determined by their ability to interact selectively with the 5'-terminal regions of cap0-, cap1- and 5'ppp- mRNAs

(2013) P. Kumar et al.   NUCLEIC ACIDS RESEARCH

BST-2/tetherin-mediated restriction of chikungunya (CHIKV) VLP budding is counteracted by CHIKV non-structural protein 1 (nsP1)

(2013) Philip H. Jones et al.   VIROLOGY

Sequestration by IFIT1 Impairs Translation of 2′O-unmethylated Capped RNA

(2013) Matthias Habjan et al.   PLoS Pathogens

IRF-3, IRF-5, and IRF-7 Coordinately Regulate the Type I IFN Response in Myeloid Dendritic Cells Downstream of MAVS Signaling

(2013) Helen M. Lazear et al.   PLoS Pathogens

Early Events in Alphavirus Replication Determine the Outcome of Infection

(2012) I. Frolov et al.   JOURNAL OF VIROLOGY

New PARP Gene with an Anti-Alphavirus Function

(2012) S. Atasheva et al.   JOURNAL OF VIROLOGY

Attenuation of Chikungunya Virus Vaccine Strain 181/Clone 25 Is Determined by Two Amino Acid Substitutions in the E2 Envelope Glycoprotein

(2012) R. Gorchakov et al.   JOURNAL OF VIROLOGY

Pseudoinfectious Venezuelan Equine Encephalitis Virus: a New Means of Alphavirus Attenuation

(2012) S. Atasheva et al.   JOURNAL OF VIROLOGY

Evasion of the Innate Immune Response: the Old World Alphavirus nsP2 Protein Induces Rapid Degradation of Rpb1, a Catalytic Subunit of RNA Polymerase II

(2012) I. Akhrymuk et al.   JOURNAL OF VIROLOGY

Multiple Interferon Stimulated Genes Synergize with the Zinc Finger Antiviral Protein to Mediate Anti-Alphavirus Activity

(2012) Sophiya Karki et al.   PLoS One

Systematic identification of type I and type II interferon-induced antiviral factors

(2012) S.-Y. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Eilat virus, a unique alphavirus with host range restricted to insects by RNA replication

(2012) F. Nasar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interferon-Induced Ifit2/ISG54 Protects Mice from Lethal VSV Neuropathogenesis

(2012) Volker Fensterl et al.   PLoS Pathogens

2′-O Methylation of the Viral mRNA Cap by West Nile Virus Evades Ifit1-Dependent and -Independent Mechanisms of Host Restriction In Vivo

(2012) Kristy J. Szretter et al.   PLoS Pathogens

Conservation of a Packaging Signal and the Viral Genome RNA Packaging Mechanism in Alphavirus Evolution

(2011) D. Y. Kim et al.   JOURNAL OF VIROLOGY

IFIT1 is an antiviral protein that recognizes 5′-triphosphate RNA

(2011) Andreas Pichlmair et al.   NATURE IMMUNOLOGY

Novel Chikungunya Vaccine Candidate with an IRES-Based Attenuation and Host Range Alteration Mechanism

(2011) Kenneth Plante et al.   PLoS Pathogens

Venezuelan Equine Encephalitis Virus Capsid Protein Forms a Tetrameric Complex with CRM1 and Importin  /  That Obstructs Nuclear Pore Complex Function

(2010) S. Atasheva et al.   JOURNAL OF VIROLOGY

Interplay of Acute and Persistent Infections Caused by Venezuelan Equine Encephalitis Virus Encoding Mutated Capsid Protein

(2010) S. Atasheva et al.   JOURNAL OF VIROLOGY

2′-O methylation of the viral mRNA cap evades host restriction by IFIT family members

(2010) Stephane Daffis et al.   NATURE

Structural and Functional Elements of the Promoter Encoded by the 5' Untranslated Region of the Venezuelan Equine Encephalitis Virus Genome

(2009) R. Kulasegaran-Shylini et al.   JOURNAL OF VIROLOGY

The 5′UTR-specific mutation in VEEV TC-83 genome has a strong effect on RNA replication and subgenomic RNA synthesis, but not on translation of the encoded proteins

(2009) Raghavendran Kulasegaran-Shylini et al.   VIROLOGY

Type I interferon induction is correlated with attenuation of a South American eastern equine encephalitis virus strain in mice

(2009) Christina L. Gardner et al.   VIROLOGY

Host responses to alphavirus infection

(2008) Kate D. Ryman et al.   IMMUNOLOGICAL REVIEWS

A New Role for ns Polyprotein Cleavage in Sindbis Virus Replication

(2008) R. Gorchakov et al.   JOURNAL OF VIROLOGY

Structural and Nonstructural Protein Genome Regions of Eastern Equine Encephalitis Virus Are Determinants of Interferon Sensitivity and Murine Virulence

(2008) P. V. Aguilar et al.   JOURNAL OF VIROLOGY