TLR4 and CD14 trafficking and its influence on LPS-induced pro-inflammatory signaling
出版年份 2020 全文链接
标题
TLR4 and CD14 trafficking and its influence on LPS-induced pro-inflammatory signaling
作者
关键词
-
出版物
CELLULAR AND MOLECULAR LIFE SCIENCES
Volume -, Issue -, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2020-10-15
DOI
10.1007/s00018-020-03656-y
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Toll-like Receptors and the Control of Immunity
- (2020) Katherine A. Fitzgerald et al. CELL
- Mutant Huntingtin affects toll-like receptor 4 intracellular trafficking and cytokine production in mast cells
- (2020) Marian Jesabel Pérez-Rodríguez et al. Journal of Neuroinflammation
- The TLR4 adaptor TRAM controls the phagocytosis of Gram-negative bacteria by interacting with the Rab11-family interacting protein 2
- (2019) Astrid Skjesol et al. PLoS Pathogens
- Sepsis: mechanisms of bacterial injury to the patient
- (2019) Hayk Minasyan Scandinavian Journal of Trauma Resuscitation & Emergency Medicine
- Syntaxin 11 regulates the stimulus-dependent transport of Toll-like receptor 4 to the plasma membrane by cooperating with SNAP-23 in macrophages
- (2019) Daiki Kinoshita et al. MOLECULAR BIOLOGY OF THE CELL
- Rab7b Overexpression–Ameliorated Ischemic Brain Damage Following tMCAO Involves Suppression of TLR4 and NF-κB p65
- (2019) Jinlong Qi et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Below the surface: The inner lives of TLR4 and TLR9
- (2019) Laura Marongiu et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Detecting lipopolysaccharide in the cytosol of mammalian cells: Lessons from MD-2/TLR4
- (2019) Jason H. Barker et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Innate Immune Signaling Organelles Display Natural and Programmable Signaling Flexibility
- (2019) Yunhao Tan et al. CELL
- Presepsin: A promising biomarker for the detection of bacterial infections
- (2019) Mohammad Yousef Memar et al. BIOMEDICINE & PHARMACOTHERAPY
- Spoiled for Choice: Diverse Endocytic Pathways Function at the Cell Surface
- (2019) Joseph Jose Thottacherry et al. Annual Review of Cell and Developmental Biology
- Saturation of acyl chains converts cardiolipin from an antagonist to an activator of Toll-like receptor-4
- (2019) Malvina Pizzuto et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- CD14: Biology and role in the pathogenesis of disease
- (2019) Zhenghao Wu et al. CYTOKINE & GROWTH FACTOR REVIEWS
- The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation
- (2019) Nathan Kelley et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Glycerol phosphate shuttle enzyme GPD2 regulates macrophage inflammatory responses
- (2019) P. Kent Langston et al. NATURE IMMUNOLOGY
- Sphingomyelin synthase activity affects TRIF-dependent signaling of Toll-like receptor 4 in cells stimulated with lipopolysaccharide
- (2019) Kamila Prymas et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Apolipoprotein C3 induces inflammation and organ damage by alternative inflammasome activation
- (2019) Stephen Zewinger et al. NATURE IMMUNOLOGY
- Lysosomal Dysfunction at the Centre of Parkinson’s Disease and Frontotemporal Dementia/Amyotrophic Lateral Sclerosis
- (2019) Rebecca L. Wallings et al. TRENDS IN NEUROSCIENCES
- Toll-like receptor 4 inhibition prevents autoimmune diabetes in NOD mice
- (2019) Mohamed Alibashe-Ahmed et al. Scientific Reports
- Endo-lysosomal dysfunction: a converging mechanism in neurodegenerative diseases
- (2018) Chao Wang et al. CURRENT OPINION IN NEUROBIOLOGY
- The Family of LPS Signal Transducers Increases: the Arrival of Chanzymes
- (2018) Francesca Granucci IMMUNITY
- Chanzyme TRPM7 Mediates the Ca 2+ Influx Essential for Lipopolysaccharide-Induced Toll-Like Receptor 4 Endocytosis and Macrophage Activation
- (2018) Michael S. Schappe et al. IMMUNITY
- The Pore-Forming Protein Gasdermin D Regulates Interleukin-1 Secretion from Living Macrophages
- (2018) Charles L. Evavold et al. IMMUNITY
- Lipopolysaccharide (LPS)-binding protein stimulates CD14-dependent Toll-like receptor 4 internalization and LPS-induced TBK1–IKKϵ–IRF3 axis activation
- (2018) Hiroki Tsukamoto et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The enigmatic endosome – sorting the ins and outs of endocytic trafficking
- (2018) Naava Naslavsky et al. JOURNAL OF CELL SCIENCE
- LPS inactivation by a host lipase allows lung epithelial cell sensitization for allergic asthma
- (2018) Guojun Qian et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Intravesicular Acidification Regulates Lipopolysaccharide Inflammation and Tolerance through TLR4 Trafficking
- (2018) Motoya Murase et al. JOURNAL OF IMMUNOLOGY
- Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B
- (2018) Morag R. Hunter et al. JOURNAL OF MOLECULAR BIOLOGY
- Crystal structure of the mammalian lipopolysaccharide detoxifier
- (2018) Alexei Gorelik et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Plasmalogens Inhibit Endocytosis of Toll-like Receptor 4 to Attenuate the Inflammatory Signal in Microglial Cells
- (2018) Fatma Ali et al. MOLECULAR NEUROBIOLOGY
- HMGB1: LPS Delivery Vehicle for Caspase-11-Mediated Pyroptosis
- (2018) Ho Min Kim et al. IMMUNITY
- The Endotoxin Delivery Protein HMGB1 Mediates Caspase-11-Dependent Lethality in Sepsis
- (2018) Meihong Deng et al. IMMUNITY
- Core fucose is essential glycosylation for CD14-dependent Toll-like receptor 4 and Toll-like receptor 2 signalling in macrophages
- (2018) Kotarosumitomo Nakayama et al. JOURNAL OF BIOCHEMISTRY
- The role of innate immunity in mucopolysaccharide diseases
- (2018) Helen Parker et al. JOURNAL OF NEUROCHEMISTRY
- Autocrine–paracrine prostaglandin E2 signaling restricts TLR4 internalization and TRIF signaling
- (2018) Darren J. Perkins et al. NATURE IMMUNOLOGY
- A novel pathway of LPS uptake through syndecan-1 leading to pyroptotic cell death
- (2018) Shigetoshi Yokoyama et al. eLife
- Core fucose is critical for CD14-dependent Toll-like receptor 4 signaling
- (2017) Junko Iijima et al. GLYCOBIOLOGY
- Reconstruction of LPS Transfer Cascade Reveals Structural Determinants within LBP, CD14, and TLR4-MD2 for Efficient LPS Recognition and Transfer
- (2017) Je-Kyung Ryu et al. IMMUNITY
- By Capturing Inflammatory Lipids Released from Dying Cells, the Receptor CD14 Induces Inflammasome-Dependent Phagocyte Hyperactivation
- (2017) Ivan Zanoni et al. IMMUNITY
- Caspase-11 non-canonical inflammasome: a critical sensor of intracellular lipopolysaccharide in macrophage-mediated inflammatory responses
- (2017) Young-Su Yi IMMUNOLOGY
- Bis(monoacylglycero)phosphate inhibits TLR4-dependent RANTES production in macrophages
- (2017) Anna Ciesielska et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Type III IFNs Are Commonly Induced by Bacteria-Sensing TLRs and Reinforce Epithelial Barriers during Infection
- (2017) Charlotte Odendall et al. JOURNAL OF IMMUNOLOGY
- Human Blood CD1c+Dendritic Cells Encompass CD5highand CD5lowSubsets That Differ Significantly in Phenotype, Gene Expression, and Functions
- (2017) Xiangyun Yin et al. JOURNAL OF IMMUNOLOGY
- Syk Plays a Critical Role in the Expression and Activation of IRAK1 in LPS-Treated Macrophages
- (2017) Jae Gwang Park et al. MEDIATORS OF INFLAMMATION
- Association of Lyn kinase with membrane rafts determines its negative influence on LPS-induced signaling
- (2017) Kinga Borzęcka-Solarz et al. MOLECULAR BIOLOGY OF THE CELL
- Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors
- (2017) Alexandra-Chloé Villani et al. SCIENCE
- Acyloxyacyl hydrolase promotes the resolution of lipopolysaccharide-induced acute lung injury
- (2017) Benkun Zou et al. PLoS Pathogens
- Toll-Like Receptor 4 Is Essential for the Expression of Sphingosine-1-Phosphate-Dependent Asthma-Like Disease in Mice
- (2017) Fiorentina Roviezzo et al. Frontiers in Immunology
- JNK Activation Turns on LPS- and Gram-Negative Bacteria-Induced NADPH Oxidase-Dependent Suicidal NETosis
- (2017) Meraj A. Khan et al. Scientific Reports
- Distinct inflammatory phenotypes of microglia and monocyte-derived macrophages in Alzheimer's disease models: effects of aging and amyloid pathology
- (2016) Elodie Martin et al. AGING CELL
- Gastrointestinal and hepatic mechanisms limiting entry and dissemination of lipopolysaccharide into the systemic circulation
- (2016) Mathilde Guerville et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Syk negatively regulates TLR4-mediated IFNβ and IL-10 production and promotes inflammatory responses in dendritic cells
- (2016) Hui Yin et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Bacterial Outer Membrane Vesicles Mediate Cytosolic Localization of LPS and Caspase-11 Activation
- (2016) Sivapriya Kailasan Vanaja et al. CELL
- Phospholipid flippases attenuate LPS-induced TLR4 signaling by mediating endocytic retrieval of Toll-like receptor 4
- (2016) Vincent A. van der Mark et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Platelets Toll-like receptor-4 in Crohns disease
- (2016) Werner Schmid et al. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
- ARC Syndrome-Linked Vps33B Protein Is Required for Inflammatory Endosomal Maturation and Signal Termination
- (2016) Mohammed Ali Akbar et al. IMMUNITY
- Lipopolysaccharide-Induced CD300b Receptor Binding to Toll-like Receptor 4 Alters Signaling to Drive Cytokine Responses that Enhance Septic Shock
- (2016) Oliver H. Voss et al. IMMUNITY
- RIPK1 and RIPK3 Kinases Promote Cell-Death-Independent Inflammation by Toll-like Receptor 4
- (2016) Malek Najjar et al. IMMUNITY
- Human Monocytes Engage an Alternative Inflammasome Pathway
- (2016) Moritz M. Gaidt et al. IMMUNITY
- Priming of the neutrophil respiratory burst: role in host defense and inflammation
- (2016) Jamel El-Benna et al. IMMUNOLOGICAL REVIEWS
- Structure and function: Lipid A modifications in commensals and pathogens
- (2016) Alex Steimle et al. INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY
- Lysosomal trafficking regulator Lyst links membrane trafficking to toll-like receptor–mediated inflammatory responses
- (2016) Andreas Westphal et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Human Host Defense Cathelicidin Peptide LL-37 Enhances the Lipopolysaccharide Uptake by Liver Sinusoidal Endothelial Cells without Cell Activation
- (2016) Kaori Suzuki et al. JOURNAL OF IMMUNOLOGY
- Raftlin Controls Lipopolysaccharide-Induced TLR4 Internalization and TICAM-1 Signaling in a Cell Type–Specific Manner
- (2016) Megumi Tatematsu et al. JOURNAL OF IMMUNOLOGY
- Blood-Borne Lipopolysaccharide Is Rapidly Eliminated by Liver Sinusoidal Endothelial Cells via High-Density Lipoprotein
- (2016) Zhili Yao et al. JOURNAL OF IMMUNOLOGY
- Contribution of CD14 and TLR4 to changes of the PI(4,5)P2 level in LPS-stimulated cells
- (2016) Agnieszka Płóciennikowska et al. JOURNAL OF LEUKOCYTE BIOLOGY
- The Role of Toll-Like Receptor 4 in Infectious and Noninfectious Inflammation
- (2016) Monica Molteni et al. MEDIATORS OF INFLAMMATION
- An endogenous caspase-11 ligand elicits interleukin-1 release from living dendritic cells
- (2016) Ivan Zanoni et al. SCIENCE
- Vps35-dependent recycling of Trem2 regulates microglial function
- (2016) Jie Yin et al. TRAFFIC
- The inflammatory microenvironment in epithelial ovarian cancer: a role for TLR4 and MyD88 and related proteins
- (2016) Zheng Li et al. TUMOR BIOLOGY
- Regulation of post-Golgi LH3 trafficking is essential for collagen homeostasis
- (2016) Blerida Banushi et al. Nature Communications
- Neutrophils Discriminate between Lipopolysaccharides of Different Bacterial Sources and Selectively Release Neutrophil Extracellular Traps
- (2016) Elmar Pieterse et al. Frontiers in Immunology
- Lipopolysaccharide Is Cleared from the Circulation by Hepatocytes via the Low Density Lipoprotein Receptor
- (2016) Elena Topchiy et al. PLoS One
- Disabled-2 is a negative immune regulator of lipopolysaccharide-stimulated Toll-like receptor 4 internalization and signaling
- (2016) Wei-Shan Hung et al. Scientific Reports
- Innate Immune Pattern Recognition: A Cell Biological Perspective
- (2015) Sky W. Brubaker et al. Annual Review of Immunology
- The effect of the size of fluorescent dextran on its endocytic pathway
- (2015) Lei Li et al. CELL BIOLOGY INTERNATIONAL
- TLR4 at the Crossroads of Nutrients, Gut Microbiota, and Metabolic Inflammation
- (2015) Licio A. Velloso et al. ENDOCRINE REVIEWS
- Postulates for validating TLR4 agonists
- (2015) Mateja Manček-Keber et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Trichuris suis soluble products induce Rab7b expression and limit TLR4 responses in human dendritic cells
- (2015) E J Klaver et al. GENES AND IMMUNITY
- Mechanisms of Toll-like Receptor 4 Endocytosis Reveal a Common Immune-Evasion Strategy Used by Pathogenic and Commensal Bacteria
- (2015) Yunhao Tan et al. IMMUNITY
- Nucleic acid-sensing TLRs and autoimmunity: novel insights from structural and cell biology
- (2015) Karin Pelka et al. IMMUNOLOGICAL REVIEWS
- LPS-induced clustering of CD14 triggers generation of PI(4,5)P2
- (2015) A. P ociennikowska et al. JOURNAL OF CELL SCIENCE
- MD-2 is required for disulfide HMGB1–dependent TLR4 signaling
- (2015) Huan Yang et al. JOURNAL OF EXPERIMENTAL MEDICINE
- CD13 Restricts TLR4 Endocytic Signal Transduction in Inflammation
- (2015) Mallika Ghosh et al. JOURNAL OF IMMUNOLOGY
- Phagocytosis by human monocytes is required for the secretion of presepsin
- (2015) Yasuyuki Arai et al. JOURNAL OF INFECTION AND CHEMOTHERAPY
- CD14 dependence of TLR4 endocytosis and TRIF signaling displays ligand specificity and is dissociable in endotoxin tolerance
- (2015) Rajesh Rajaiah et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- LYST Controls the Biogenesis of the Endosomal Compartment Required for Secretory Lysosome Function
- (2015) Fernando E. Sepulveda et al. TRAFFIC
- CD14, TLR4 and TRAM Show Different Trafficking Dynamics During LPS Stimulation
- (2015) Dionne C.G. Klein et al. TRAFFIC
- Insights into the species-specific TLR4 signaling mechanism in response to Rhodobacter sphaeroides lipid A detection
- (2015) Muhammad Ayaz Anwar et al. Scientific Reports
- Toll-like Receptor 4 Is Essential to Preserving Cardiac Function and Survival in Low-grade Polymicrobial Sepsis
- (2014) Ming Zhang et al. ANESTHESIOLOGY
- TLR Signals Induce Phagosomal MHC-I Delivery from the Endosomal Recycling Compartment to Allow Cross-Presentation
- (2014) Priyanka Nair-Gupta et al. CELL
- A Promiscuous Lipid-Binding Protein Diversifies the Subcellular Sites of Toll-like Receptor Signal Transduction
- (2014) Kevin S. Bonham et al. CELL
- Co-operation of TLR4 and raft proteins in LPS-induced pro-inflammatory signaling
- (2014) Agnieszka Płóciennikowska et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Identification of novel mutations in theVPS33Bgene involved in arthrogryposis, renal dysfunction, and cholestasis syndrome
- (2014) S. H. Seo et al. CLINICAL GENETICS
- Soluble CD14 is essential for lipopolysaccharide-dependent activation of human intestinal mast cells from macroscopically normal as well as Crohn's disease tissue
- (2014) Sibylle A. Brenner et al. IMMUNOLOGY
- Dual Signaling of MyD88 and TRIF Is Critical for Maximal TLR4-Induced Dendritic Cell Maturation
- (2014) H. Shen et al. JOURNAL OF IMMUNOLOGY
- Biological role of Toll-like receptor-4 in the brain
- (2014) Teresa Trotta et al. JOURNAL OF NEUROIMMUNOLOGY
- Galectin-3 drives glycosphingolipid-dependent biogenesis of clathrin-independent carriers
- (2014) Ramya Lakshminarayan et al. NATURE CELL BIOLOGY
- TLR-driven early glycolytic reprogramming via the kinases TBK1-IKKɛ supports the anabolic demands of dendritic cell activation
- (2014) Bart Everts et al. NATURE IMMUNOLOGY
- Population Distribution Analyses Reveal a Hierarchy of Molecular Players Underlying Parallel Endocytic Pathways
- (2014) Gagan D. Gupta et al. PLoS One
- Integrin CD11b positively regulates TLR4-induced signalling pathways in dendritic cells but not in macrophages
- (2014) Guang Sheng Ling et al. Nature Communications
- A Comparative Review of Toll-Like Receptor 4 Expression and Functionality in Different Animal Species
- (2014) Céline Vaure et al. Frontiers in Immunology
- Toll-like receptor 4 is not targeted to the lysosome in cystic fibrosis airway epithelial cells
- (2013) Catriona Kelly et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- MD-2-dependent human Toll-like receptor 4 monoclonal antibodies detect extracellular association of Toll-like receptor 4 with extrinsic soluble MD-2 on the cell surface
- (2013) Hiroki Tsukamoto et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- An interplay between scavenger receptor A and CD14 during activation of J774 cells by high concentrations of LPS
- (2013) Maciej Czerkies et al. IMMUNOBIOLOGY
- The Small GTPase Arf6 Is Essential for the Tram/Trif Pathway in TLR4 Signaling
- (2013) Tim Van Acker et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- CD14 Mediates Toll-like Receptor 4 (TLR4) Endocytosis and Spleen Tyrosine Kinase (Syk) and Interferon Regulatory Transcription Factor 3 (IRF3) Activation in Epithelial Cells and Impairs Neutrophil Infiltration andPseudomonas aeruginosaKillingin Vivo
- (2013) Sanhita Roy et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Toll-like Receptor 3-mediated Necrosis via TRIF, RIP3, and MLKL
- (2013) William J. Kaiser et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Glia Maturation Factor- Negatively Modulates TLR4 Signaling by Facilitating TLR4 Endocytic Trafficking in Macrophages
- (2013) W. Aerbajinai et al. JOURNAL OF IMMUNOLOGY
- Lipopolysaccharide Clearance, Bacterial Clearance, and Systemic Inflammatory Responses Are Regulated by Cell Type-Specific Functions of TLR4 during Sepsis
- (2013) M. Deng et al. JOURNAL OF IMMUNOLOGY
- Human blood mDC subsets exhibit distinct TLR repertoire and responsiveness
- (2013) Caroline Hémont et al. JOURNAL OF LEUKOCYTE BIOLOGY
- LPS or ethanol triggers clathrin- and rafts/caveolae-dependent endocytosis of TLR4 in cortical astrocytes
- (2013) Maya Pascual-Lucas et al. JOURNAL OF NEUROCHEMISTRY
- CD14 Mediates Binding of High Doses of LPS but Is Dispensable for TNF-αProduction
- (2013) Kinga Borzęcka et al. MEDIATORS OF INFLAMMATION
- Liposomal Lipopolysaccharide Initiates TRIF-Dependent Signaling Pathway Independent of CD14
- (2013) Sachiko Watanabe et al. PLoS One
- Intestinal alkaline phosphatase prevents metabolic syndrome in mice
- (2013) K. Kaliannan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Direct Proteomic Quantification of the Secretome of Activated Immune Cells
- (2013) F. Meissner et al. SCIENCE
- The BEACH Is Hot: A LYST of Emerging Roles for BEACH-Domain Containing Proteins in Human Disease
- (2013) Andrew R. Cullinane et al. TRAFFIC
- Epidemiology of severe sepsis
- (2013) Florian B Mayr et al. Virulence
- Animal models of sepsis
- (2013) Mitchell P Fink Virulence
- Inhibition of clathrin/dynamin-dependent internalization interferes with LPS-mediated TRAM–TRIF-dependent signaling pathway
- (2012) Yanyan Wang et al. CELLULAR IMMUNOLOGY
- Hepatic uptake and deacylation of the LPS in bloodborne LPS-lipoprotein complexes
- (2012) Baomei Shao et al. Innate Immunity
- The Crystal Structure of Human Soluble CD14 Reveals a Bent Solenoid with a Hydrophobic Amino-Terminal Pocket
- (2012) S. L. Kelley et al. JOURNAL OF IMMUNOLOGY
- TLR4-Mediated AKT Activation Is MyD88/TRIF Dependent and Critical for Induction of Oxidative Phosphorylation and Mitochondrial Transcription Factor A in Murine Macrophages
- (2012) C. P. Bauerfeld et al. JOURNAL OF IMMUNOLOGY
- The p110δ isoform of the kinase PI(3)K controls the subcellular compartmentalization of TLR4 signaling and protects from endotoxic shock
- (2012) Ezra Aksoy et al. NATURE IMMUNOLOGY
- Toll-like receptor 4 signaling in T cells promotes autoimmune inflammation
- (2012) J. M. Reynolds et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural basis of species-specific endotoxin sensing by innate immune receptor TLR4/MD-2
- (2012) U. Ohto et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The GOLD domain-containing protein TMED7 inhibits TLR4 signalling from the endosome upon LPS stimulation
- (2012) Sarah L. Doyle et al. Nature Communications
- Humanized TLR4/MD-2 Mice Reveal LPS Recognition Differentially Impacts Susceptibility to Yersinia pestis and Salmonella enterica
- (2012) Adeline M. Hajjar et al. PLoS Pathogens
- CD14 Controls the LPS-Induced Endocytosis of Toll-like Receptor 4
- (2011) Ivan Zanoni et al. CELL
- CD14 Modulates Inflammation-Driven Insulin Resistance
- (2011) J. M. Fernandez-Real et al. DIABETES
- Notch2 Receptor Signaling Controls Functional Differentiation of Dendritic Cells in the Spleen and Intestine
- (2011) Kanako L. Lewis et al. IMMUNITY
- Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity
- (2011) Taro Kawai et al. IMMUNITY
- TLR-induced activation of neutrophils promotes histamine production via a PI3 kinase dependent mechanism
- (2011) Craig Smuda et al. IMMUNOLOGY LETTERS
- Pathogen Recognition by the Innate Immune System
- (2011) Himanshu Kumar et al. INTERNATIONAL REVIEWS OF IMMUNOLOGY
- The Ectodomain of the Toll-like Receptor 4 Prevents Constitutive Receptor Activation
- (2011) Gabriela Panter et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Phospholipase Cγ-2 and Intracellular Calcium Are Required for Lipopolysaccharide-induced Toll-like Receptor 4 (TLR4) Endocytosis and Interferon Regulatory Factor 3 (IRF3) Activation
- (2011) Chih-Yuan Chiang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Transport and Inactivation Kinetics of Bacterial Lipopolysaccharide Influence Its Immunological Potency In Vivo
- (2011) M. Lu et al. JOURNAL OF IMMUNOLOGY
- Absence of TRIF Signaling in Lipopolysaccharide-Stimulated Murine Mast Cells
- (2011) S. Keck et al. JOURNAL OF IMMUNOLOGY
- Genome-Wide Expression Profiling and Mutagenesis Studies Reveal that Lipopolysaccharide Responsiveness Appears To Be Absolutely Dependent on TLR4 and MD-2 Expression and Is Dependent upon Intermolecular Ionic Interactions
- (2011) J. Meng et al. JOURNAL OF IMMUNOLOGY
- Abnormal Trafficking and Degradation of TLR4 Underlie the Elevated Inflammatory Response in Cystic Fibrosis
- (2011) E. M. Bruscia et al. JOURNAL OF IMMUNOLOGY
- Targeting Toll-like receptors: Emerging therapeutics for multiple sclerosis management
- (2011) M. Gambuzza et al. JOURNAL OF NEUROIMMUNOLOGY
- Toll-like receptor signaling in amyotrophic lateral sclerosis spinal cord tissue
- (2011) M. Casula et al. NEUROSCIENCE
- B-cell adaptor for PI3K (BCAP) negatively regulates Toll-like receptor signaling through activation of PI3K
- (2011) M. Ni et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Role for B-cell adapter for PI3K (BCAP) as a signaling adapter linking Toll-like receptors (TLRs) to serine/threonine kinases PI3K/Akt
- (2011) T. D. Troutman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Toll-like receptors activate programmed necrosis in macrophages through a receptor-interacting kinase-3-mediated pathway
- (2011) S. He et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Different dimerisation mode for TLR4 upon endosomal acidification?
- (2011) Monique Gangloff TRENDS IN BIOCHEMICAL SCIENCES
- Regulation of the autophagic machinery in human neutrophils
- (2010) Ioannis Mitroulis et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- The Rab11a GTPase Controls Toll-like Receptor 4-Induced Activation of Interferon Regulatory Factor-3 on Phagosomes
- (2010) Harald Husebye et al. IMMUNITY
- Neisseria meningitidis lipid A mutant LPSs function as LPS antagonists in humans by inhibiting TLR 4-dependent cytokine production
- (2010) Tom Sprong et al. Innate Immunity
- Rab7b controls trafficking from endosomes to the TGN
- (2010) C. Progida et al. JOURNAL OF CELL SCIENCE
- Human CD141+(BDCA-3)+dendritic cells (DCs) represent a unique myeloid DC subset that cross-presents necrotic cell antigens
- (2010) Sarah L. Jongbloed et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Deletion of CD14 Attenuates Alzheimer's Disease Pathology by Influencing the Brain's Inflammatory Milieu
- (2010) E. G. Reed-Geaghan et al. JOURNAL OF NEUROSCIENCE
- Helical assembly in the MyD88–IRAK4–IRAK2 complex in TLR/IL-1R signalling
- (2010) Su-Chang Lin et al. NATURE
- Mast cells elicit proinflammatory but not type I interferon responses upon activation of TLRs by bacteria
- (2010) N. Dietrich et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Ras-related protein Rab10 facilitates TLR4 signaling by promoting replenishment of TLR4 onto the plasma membrane
- (2010) D. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Chaperones and transport proteins regulate TLR4 trafficking and activation
- (2009) Shin-Ichiroh Saitoh IMMUNOBIOLOGY
- Analysis of Cd14 as a genetic modifier of experimental inflammatory bowel disease (IBD) in mice
- (2009) Maike F. de Buhr et al. INFLAMMATORY BOWEL DISEASES
- MD-2-mediated Ionic Interactions between Lipid A and TLR4 Are Essential for Receptor Activation
- (2009) Jianmin Meng et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- An Oligomeric Signaling Platform Formed by the Toll-like Receptor Signal Transducers MyD88 and IRAK-4
- (2009) Precious G. Motshwene et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cutting Edge: TNF- Mediates Sensitization to ATP and Silica via the NLRP3 Inflammasome in the Absence of Microbial Stimulation
- (2009) L. Franchi et al. JOURNAL OF IMMUNOLOGY
- TLR4/MyD88/PI3K interactions regulate TLR4 signaling
- (2009) Michelle H. W. Laird et al. JOURNAL OF LEUKOCYTE BIOLOGY
- CD14 and Toll-Like Receptors 2 and 4 Are Required for Fibrillar A -Stimulated Microglial Activation
- (2009) E. G. Reed-Geaghan et al. JOURNAL OF NEUROSCIENCE
- CD14 regulates the dendritic cell life cycle after LPS exposure through NFAT activation
- (2009) Ivan Zanoni et al. NATURE
- The structural basis of lipopolysaccharide recognition by the TLR4–MD-2 complex
- (2009) Beom Seok Park et al. NATURE
- TAG, a splice variant of the adaptor TRAM, negatively regulates the adaptor MyD88–independent TLR4 pathway
- (2009) Eva M Palsson-McDermott et al. NATURE IMMUNOLOGY
- Pathways and mechanisms of endocytic recycling
- (2009) Barth D. Grant et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Differential regulation of toll-like receptor mRNAs in amyloid plaque-associated brain tissue of aged APP23 transgenic mice
- (2009) Stefanie Frank et al. NEUROSCIENCE LETTERS
- Involvement of the Toll-like receptor 4 pathway and use of TNF- antagonists for treatment of the mucopolysaccharidoses
- (2009) C. M. Simonaro et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Macrophages Directly Contribute to the Exaggerated Inflammatory Response in Cystic Fibrosis Transmembrane Conductance Regulator−/−Mice
- (2008) Emanuela M. Bruscia et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Roles for LPS-dependent interaction and relocation of TLR4 and TRAM in TRIF-signaling
- (2008) Natsuko Tanimura et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Differential requirement for the activation of the inflammasome for processing and release of IL-1 in monocytes and macrophages
- (2008) M. G. Netea et al. BLOOD
- LPS/TLR4 signal transduction pathway
- (2008) Yong-Chen Lu et al. CYTOKINE
- Changes in Gut Microbiota Control Metabolic Endotoxemia-Induced Inflammation in High-Fat Diet-Induced Obesity and Diabetes in Mice
- (2008) P. D. Cani et al. DIABETES
- Toll-like receptor-4 mediates neuronal apoptosis induced by amyloid β-peptide and the membrane lipid peroxidation product 4-hydroxynonenal
- (2008) Sung-Chun Tang et al. EXPERIMENTAL NEUROLOGY
- β2-Integrin-induced p38 MAPK Activation Is a Key Mediator in the CD14/TLR4/MD2-dependent Uptake of Lipopolysaccharide by Hepatocytes
- (2008) Melanie J. Scott et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Regulation of retromer recruitment to endosomes by sequential action of Rab5 and Rab7
- (2008) Raul Rojas et al. JOURNAL OF CELL BIOLOGY
- TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-β
- (2008) Jonathan C Kagan et al. NATURE IMMUNOLOGY
- Early Neurodegeneration Progresses Independently of Microglial Activation by Heparan Sulfate in the Brain of Mucopolysaccharidosis IIIB Mice
- (2008) Jérôme Ausseil et al. PLoS One
- Mechanism of Glycosaminoglycan-Mediated Bone and Joint Disease
- (2007) Calogera M. Simonaro et al. AMERICAN JOURNAL OF PATHOLOGY
- Screening of innate immune receptors in neurodegenerative diseases: A similar pattern
- (2007) Maryse Letiembre et al. NEUROBIOLOGY OF AGING
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search