The Essential Functions and Detection of Bisecting GlcNAc in Cell Biology

3D Structure and Function of Glycosyltransferases Involved in N-glycan Maturation

(2020) Masamichi Nagae et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Glycosylation in health and disease

(2019) Colin Reily et al.   Nature Reviews Nephrology

Recognition of Bisecting N-Glycans on Intact Glycopeptides by Two Characteristic Ions in Tandem Mass Spectra

(2019) Liuyi Dang et al.   ANALYTICAL CHEMISTRY

Bisecting GlcNAc Is a General Suppressor of Terminal Modification of N-glycan

(2019) Miyako Nakano et al.   MOLECULAR & CELLULAR PROTEOMICS

E-cadherin is required for metastasis in multiple models of breast cancer

(2019) Veena Padmanaban et al.   NATURE

The Potential Role of Seminal Plasma in the Fertilization Outcomes

(2019) Justyna Szczykutowicz et al.   Biomed Research International

Specific Sialoforms Required for the Immune Suppressive Activity of Human Soluble CD52

(2019) Abdulrahman M. Shathili et al.   Frontiers in Immunology

Native Hydrophobic Interaction Chromatography Hyphenated to Mass Spectrometry for Characterization of Monoclonal Antibody Minor Variants

(2019) Bingchuan Wei et al.   ANALYTICAL CHEMISTRY

Lectin-Based Method for Deciphering Human Milk IgG Sialylation

(2019) Jolanta Lis-Kuberka et al.   MOLECULES

Glycan biomarkers for Alzheimer disease correlate with T‐tau and P‐tau in cerebrospinal fluid in subjective cognitive impairment

(2019) Sophia Schedin‐Weiss et al.   FEBS Journal

Convergent Synthesis of a Bisecting N -Acetylglucosamine (GlcNAc)-Containing N-Glycan

(2018) Yoshiyuki Manabe et al.   Chemistry-An Asian Journal

The glycomic effect of N-acetylglucosaminyltransferase III overexpression in metastatic melanoma cells. GnT-III modifies highly branched N-glycans

(2018) Paweł Link-Lenczowski et al.   GLYCOCONJUGATE JOURNAL

Neural functions of bisecting GlcNAc

(2018) Yasuhiko Kizuka et al.   GLYCOCONJUGATE JOURNAL

Bisecting N-Acetylglucosamine Structures Inhibit Hypoxia-Induced Epithelial-Mesenchymal Transition in Breast Cancer Cells

(2018) Zengqi Tan et al.   Frontiers in Physiology

A Single Route to Mammalian N-Glycans substituted with Core Fucose and Bisecting GlcNAc

(2018) Carlo Unverzagt et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Immunoglobulin G glycosylation in aging and diseases

(2018) Ivan Gudelj et al.   CELLULAR IMMUNOLOGY

Chemoenzymatic synthesis of glycopeptides bearing rare N-glycan sequences with or without bisecting GlcNAc

(2018) Weizhun Yang et al.   Chemical Science

Profiling the N-Glycan Composition of IgG with Lectins and Capillary Nanogel Electrophoresis

(2018) Grace Lu et al.   ANALYTICAL CHEMISTRY

Glycosylation of IgG-Fc: a molecular perspective

(2017) Masato Kiyoshi et al.   INTERNATIONAL IMMUNOLOGY

Sialyl Lewisx expression at the invasive front as a predictive marker of liver recurrence in stage�II colorectal cancer

(2017) Masato Yamadera et al.   Oncology Letters

Immune recruitment or suppression by glycan engineering of endogenous and therapeutic antibodies

(2016) Ngoc Phuong Lan Le et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Alzheimer's disease

(2016) Philip Scheltens et al.   LANCET

Defeating Alzheimer's disease and other dementias: a priority for European science and society

(2016) Bengt Winblad et al.   LANCET NEUROLOGY

Evidence for Differential Glycosylation of Trophoblast Cell Types

(2016) Qiushi Chen et al.   MOLECULAR & CELLULAR PROTEOMICS

The human fetoembryonic defense system hypothesis: Twenty years on

(2016) Poh-Choo Pang et al.   MOLECULAR ASPECTS OF MEDICINE

Epigenetic regulation of neuralN-glycomics

(2016) Yasuhiko Kizuka et al.   PROTEOMICS

Role of Glycans in Cancer Cells Undergoing Epithelial–Mesenchymal Transition

(2016) Xiang Li et al.   Frontiers in Oncology

Atomic visualization of a flipped-back conformation of bisected glycans bound to specific lectins

(2016) Masamichi Nagae et al.   Scientific Reports

Multi-level glyco-engineering techniques to generate IgG with defined Fc-glycans

(2016) Gillian Dekkers et al.   Scientific Reports

Bisecting GlcNAc modification stabilizes BACE1 protein under oxidative stress conditions

(2015) Y. Kizuka et al.   BIOCHEMICAL JOURNAL

An aberrant sugar modification of BACE1 blocks its lysosomal targeting in Alzheimer's disease

(2015) Y. Kizuka et al.   EMBO Molecular Medicine

Altered β1,6-GlcNAc and bisecting GlcNAc-branched N-glycan on integrin β1 are associated with early spontaneous miscarriage in humans

(2015) Min Zhang et al.   HUMAN REPRODUCTION

Glycans in the immune system and The Altered Glycan Theory of Autoimmunity: A critical review

(2015) Emanual Maverakis et al.   JOURNAL OF AUTOIMMUNITY

Processing of complex N-glycans in IgG Fc-region is affected by core fucosylation

(2015) Alexandra Castilho et al.   mAbs

The Cytotoxicity of Elderberry Ribosome-Inactivating Proteins Is Not Solely Determined by Their Protein Translation Inhibition Activity

(2015) Chenjing Shang et al.   PLoS One

Glycomic Analysis of Membrane Glycoproteins with Bisecting Glycosylation from Ovarian Cancer Tissues Reveals Novel Structures and Functions

(2014) Heba Allam et al.   JOURNAL OF PROTEOME RESEARCH

The role of protein glycosylation in Alzheimer disease

(2013) Sophia Schedin-Weiss et al.   FEBS Journal

Complex N-glycans: the story of the “yellow brick road”

(2013) Harry Schachter   GLYCOCONJUGATE JOURNAL

Recognition of BisectingN-Acetylglucosamine

(2013) Masamichi Nagae et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The role of glycans in immune evasion: the human fetoembryonic defence system hypothesis revisited

(2013) Gary F. Clark   MOLECULAR HUMAN REPRODUCTION

Insulin/IGF-I Signaling Pathways Enhances Tumor Cell Invasion through Bisecting GlcNAc N-glycans Modulation. An Interplay with E-Cadherin

(2013) Julio Cesar Madureira de-Freitas-Junior et al.   PLoS One

Branched N-glycans and their implications for cell adhesion, signaling and clinical applications for cancer biomarkers and in therapeutics

(2012) Naoyuki Taniguchi et al.   BMB Reports

Potential roles of N-glycosylation in cell adhesion

(2012) Jianguo Gu et al.   GLYCOCONJUGATE JOURNAL

The bisecting GlcNAc in cell growth control and tumor progression

(2012) Hazuki E. Miwa et al.   GLYCOCONJUGATE JOURNAL

N-Glycosylation engineering of plants for the biosynthesis of glycoproteins with bisected and branched complex N-glycans

(2011) Alexandra Castilho et al.   GLYCOBIOLOGY

Chemoenzymatic Synthesis and Fcγ Receptor Binding of Homogeneous Glycoforms of Antibody Fc Domain. Presence of a Bisecting Sugar Moiety Enhances the Affinity of Fc to FcγIIIa Receptor

(2011) Guozhang Zou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dementia: A problem for our age

(2011) Alison Abbott   NATURE

Site-specific characterization of threonine, serine, and tyrosine glycosylations of amyloid precursor protein/amyloid  -peptides in human cerebrospinal fluid

(2011) A. Halim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IgG Fc N-Glycosylation Changes in Lambert-Eaton Myasthenic Syndrome and Myasthenia Gravis

(2010) Maurice H. J. Selman et al.   JOURNAL OF PROTEOME RESEARCH

Core fucose and bisecting GlcNAc, the direct modifiers of the N-glycan core: their functions and target proteins

(2009) Motoko Takahashi et al.   CARBOHYDRATE RESEARCH

Protective effect of N-glycan bisecting GlcNAc residues on  -amyloid production in Alzheimer's disease

(2009) K. Akasaka-Manya et al.   GLYCOBIOLOGY

The role of N-acetylglucosaminyltransferase III and V in the post-transcriptional modifications of E-cadherin

(2009) S. S. Pinho et al.   HUMAN MOLECULAR GENETICS

Convenient Synthesis of anN-Glycan Octasaccharide of the Bisecting Type

(2009) Guangfa Wang et al.   JOURNAL OF ORGANIC CHEMISTRY

Structure and Function of β -1,4-Galactosyltransferase

(2008) Pradman Qasba et al.   CURRENT DRUG TARGETS

Increased bisecting and core-fucosylated N-glycans on mutant human amyloid precursor proteins

(2008) Keiko Akasaka-Manya et al.   GLYCOCONJUGATE JOURNAL

N-Glycosylation of Laminin-332 Regulates Its Biological Functions

(2008) Yoshinobu Kariya et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Mutual Regulation between Cell−Cell Adhesion and N-Glycosylation: Implication of the Bisecting GlcNAc for Biological Functions

(2008) Jianguo Gu et al.   JOURNAL OF PROTEOME RESEARCH