Processing of complex N-glycans in IgG Fc-region is affected by core fucosylation

Structure of FcγRI in complex with Fc reveals the importance of glycan recognition for high-affinity IgG binding

(2015) Jinghua Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Plant Molecular Pharming for the Treatment of Chronic and Infectious Diseases

(2014) Eva Stoger et al.   Annual Review of Plant Biology

Obinutuzumab (GA101) in relapsed/refractory chronic lymphocytic leukemia: final data from the phase 1/2 GAUGUIN study

(2014) G. Cartron et al.   BLOOD

A Phase 3, multicenter, open-label, switchover trial to assess the safety and efficacy of taliglucerase alfa, a plant cell-expressed recombinant human glucocerebrosidase, in adult and pediatric patients with Gaucher disease previously treated with imiglucerase

(2014) Gregory M. Pastores et al.   BLOOD CELLS MOLECULES AND DISEASES

Molecular Dynamics Simulation of the Crystallizable Fragment of IgG1—Insights for the Design of Fcabs

(2014) Balder Lai et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Structural Characterization of Anti-Inflammatory Immunoglobulin G Fc Proteins

(2014) Alysia A. Ahmed et al.   JOURNAL OF MOLECULAR BIOLOGY

Immunoglobulin G1 Fc Domain Motions: Implications for Fc Engineering

(2014) Martin Frank et al.   JOURNAL OF MOLECULAR BIOLOGY

Tibetan plateau gets wired up for monsoon prediction

(2014) Jane Qiu   NATURE

Biological significance of complex N-glycans in plants and their impact on plant physiology

(2014) Richard Strasser   Frontiers in Plant Science

Correct primary structure assessment and extensive glyco-profiling of cetuximab by a combination of intact, middle-up, middle-down and bottom-up ESI and MALDI mass spectrometry techniques

(2013) Daniel Ayoub et al.   mAbs

Glycoproteomic Analysis of Antibodies

(2013) Gerhild Zauner et al.   MOLECULAR & CELLULAR PROTEOMICS

Crystal structure of sialylated IgG Fc: Implications for the mechanism of intravenous immunoglobulin therapy

(2013) M. Crispin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

General mechanism for modulating immunoglobulin effector function

(2013) P. Sondermann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IgG-Fc glycoengineering in non-mammalian expression hosts

(2012) Andreas Loos et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Isotype and glycoform selection for antibody therapeutics

(2012) Roy Jefferis   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Glycan profiles of the 27 N-glycosylation sites of the HIV envelope protein CN54gp140

(2012) Martin Pabst et al.   BIOLOGICAL CHEMISTRY

Quantitative glycan profiling of normal human plasma derived immunoglobulin and its fragments Fab and Fc

(2012) Kalyan Rao Anumula   JOURNAL OF IMMUNOLOGICAL METHODS

N-Glycosylation engineering of plants for the biosynthesis of glycoproteins with bisected and branched complex N-glycans

(2011) Alexandra Castilho et al.   GLYCOBIOLOGY

Rapid High Yield Production of Different Glycoforms of Ebola Virus Monoclonal Antibody

(2011) Alexandra Castilho et al.   PLoS One

Unique carbohydrate-carbohydrate interactions are required for high affinity binding between Fc RIII and antibodies lacking core fucose

(2011) C. Ferrara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In PlantaProtein Sialylation through Overexpression of the Respective Mammalian Pathway

(2010) Alexandra Castilho et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Analytical and Functional Aspects of Antibody Sialylation

(2010) Johannes Stadlmann et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Improved Virus Neutralization by Plant-produced Anti-HIV Antibodies with a Homogeneous β1,4-GalactosylatedN-Glycan Profile

(2009) Richard Strasser et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glycosylation Site-Specific Analysis of Clade C HIV-1 Envelope Proteins

(2009) Eden P. Go et al.   JOURNAL OF PROTEOME RESEARCH

Anti-Inflammatory Actions of Intravenous Immunoglobulin

(2008) Falk Nimmerjahn et al.   Annual Review of Immunology

Generation of glyco-engineered Nicotiana benthamiana for the production of monoclonal antibodies with a homogeneous human-like N-glycan structure

(2008) Richard Strasser et al.   PLANT BIOTECHNOLOGY JOURNAL

Construction of a Functional CMP-Sialic Acid Biosynthesis Pathway in Arabidopsis

(2008) A. Castilho et al.   PLANT PHYSIOLOGY

Analysis of immunoglobulin glycosylation by LC-ESI-MS of glycopeptides and oligosaccharides

(2008) Johannes Stadlmann et al.   PROTEOMICS