标题
Glycosylation of IgG-Fc: a molecular perspective
作者
关键词
-
出版物
INTERNATIONAL IMMUNOLOGY
Volume 29, Issue 7, Pages 311-317
出版商
Oxford University Press (OUP)
发表日期
2017-06-24
DOI
10.1093/intimm/dxx038
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Modulating IgG effector function by Fc glycan engineering
- (2017) Tiezheng Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Stabilizing the CH2 Domain of an Antibody by Engineering in an Enhanced Aromatic Sequon
- (2016) Wentao Chen et al. ACS Chemical Biology
- A Perspective on the Structure and Receptor Binding Properties of Immunoglobulin G Fc
- (2015) Quinlin M. Hanson et al. BIOCHEMISTRY
- Structural analysis of Fc/FcγR complexes: a blueprint for antibody design
- (2015) Jose M. M. Caaveiro et al. IMMUNOLOGICAL REVIEWS
- Antibody Glycosylation and Its Impact on the Pharmacokinetics and Pharmacodynamics of Monoclonal Antibodies and Fc-Fusion Proteins
- (2015) Liming Liu JOURNAL OF PHARMACEUTICAL SCIENCES
- Examination of Thermal Unfolding and Aggregation Profiles of a Series of Developable Therapeutic Monoclonal Antibodies
- (2015) Mark L. Brader et al. MOLECULAR PHARMACEUTICS
- Structure of full-length human anti-PD1 therapeutic IgG4 antibody pembrolizumab
- (2015) Giovanna Scapin et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The Structural Role of Antibody N-Glycosylation in Receptor Interactions
- (2015) Ganesh P. Subedi et al. STRUCTURE
- Structural basis for binding of human IgG1 to its high-affinity human receptor FcγRI
- (2015) Masato Kiyoshi et al. Nature Communications
- Structure of full-length human anti-PD1 therapeutic IgG4 antibody pembrolizumab
- (2015) Giovanna Scapin et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Glycoengineered Monoclonal Antibodies with Homogeneous Glycan (M3, G0, G2, and A2) Using a Chemoenzymatic Approach Have Different Affinities for FcγRIIIa and Variable Antibody-Dependent Cellular Cytotoxicity Activities
- (2015) Masaki Kurogochi et al. PLoS One
- Multi-Angle Effector Function Analysis of Human Monoclonal IgG Glycovariants
- (2015) Tetyana Dashivets et al. PLoS One
- Intramolecular N-Glycan/Polypeptide Interactions Observed at Multiple N-Glycan Remodeling Steps through [13C,15N]-N-Acetylglucosamine Labeling of Immunoglobulin G1
- (2014) Adam W. Barb BIOCHEMISTRY
- Structural Characterization of Anti-Inflammatory Immunoglobulin G Fc Proteins
- (2014) Alysia A. Ahmed et al. JOURNAL OF MOLECULAR BIOLOGY
- Immunoglobulin G1 Fc Domain Motions: Implications for Fc Engineering
- (2014) Martin Frank et al. JOURNAL OF MOLECULAR BIOLOGY
- Type I and type II Fc receptors regulate innate and adaptive immunity
- (2014) Andrew Pincetic et al. NATURE IMMUNOLOGY
- Obinutuzumab plus Chlorambucil in Patients with CLL and Coexisting Conditions
- (2014) Valentin Goede et al. NEW ENGLAND JOURNAL OF MEDICINE
- Restricted Motion of the Conserved Immunoglobulin G1 N-Glycan Is Essential for Efficient FcγRIIIa Binding
- (2014) Ganesh P. Subedi et al. STRUCTURE
- Structural Basis for Selective Recognition of Endogenous and Microbial Polysaccharides by Macrophage Receptor SIGN-R1
- (2014) Noella Silva-Martín et al. STRUCTURE
- Engineering Hydrophobic Protein–Carbohydrate Interactions to Fine-Tune Monoclonal Antibodies
- (2013) Xiaojie Yu et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Consequences of glycan truncation on Fc structural integrity
- (2013) Patrick M Buck et al. mAbs
- Engineered antibody Fc variant with selectively enhanced Fc RIIb binding over both Fc RIIaR131 and Fc RIIaH131
- (2013) F. Mimoto et al. PROTEIN ENGINEERING DESIGN & SELECTION
- Revisiting the Role of Glycosylation in the Structure of Human IgG Fc
- (2012) M. Jack Borrok et al. ACS Chemical Biology
- NMR Characterization of Immunoglobulin G Fc Glycan Motion on Enzymatic Sialylation
- (2012) Adam W. Barb et al. BIOCHEMISTRY
- Function and 3D Structure of the N-Glycans on Glycoproteins
- (2012) Masamichi Nagae et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The impact of glycosylation on monoclonal antibody conformation and stability
- (2012) Kai Zheng et al. mAbs
- Marketing approval of mogamulizumab
- (2012) Alain Beck et al. mAbs
- Structural basis for improved efficacy of therapeutic antibodies on defucosylation of their Fc glycans
- (2011) Tsunehiro Mizushima et al. GENES TO CELLS
- NMR analysis demonstrates immunoglobulin G N-glycans are accessible and dynamic
- (2011) Adam W Barb et al. Nature Chemical Biology
- Unique carbohydrate-carbohydrate interactions are required for high affinity binding between Fc RIII and antibodies lacking core fucose
- (2011) C. Ferrara et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Glycosylation influences on the aggregation propensity of therapeutic monoclonal antibodies
- (2010) Veysel Kayser et al. Biotechnology Journal
- Post-translational Modifications Differentially Affect IgG1 Conformation and Receptor Binding
- (2010) Damian Houde et al. MOLECULAR & CELLULAR PROTEOMICS
- Naturally occurring glycan forms of human immunoglobulins G1 and G2
- (2010) Gregory C. Flynn et al. MOLECULAR IMMUNOLOGY
- Therapeutic IgG4 antibodies engage in Fab-arm exchange with endogenous human IgG4 in vivo
- (2009) Aran F Labrijn et al. NATURE BIOTECHNOLOGY
- Glycosylation as a strategy to improve antibody-based therapeutics
- (2009) Roy Jefferis NATURE REVIEWS DRUG DISCOVERY
- Dynamic Fluctuations of Protein-Carbohydrate Interactions Promote Protein Aggregation
- (2009) Vladimir Voynov et al. PLoS One
- Specificity and affinity of human Fc receptors and their polymorphic variants for human IgG subclasses
- (2008) P. Bruhns et al. BLOOD
- Terminal sugars of Fc glycans influence antibody effector functions of IgGs
- (2008) T Shantha Raju CURRENT OPINION IN IMMUNOLOGY
- Optimization of antibody binding to Fc RIIa enhances macrophage phagocytosis of tumor cells
- (2008) J. O. Richards et al. MOLECULAR CANCER THERAPEUTICS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started