Insulin/IGF-I Signaling Pathways Enhances Tumor Cell Invasion through Bisecting GlcNAc N-glycans Modulation. An Interplay with E-Cadherin

Somatic Mutations and Deletions of the E-Cadherin Gene Predict Poor Survival of Patients With Gastric Cancer

(2013) Giovanni Corso et al.   JOURNAL OF CLINICAL ONCOLOGY

E-cadherin and adherens-junctions stability in gastric carcinoma: Functional implications of glycosyltransferases involving N-glycan branching biosynthesis, N-acetylglucosaminyltransferases III and V

(2012) Salomé S. Pinho et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

The bisecting GlcNAc in cell growth control and tumor progression

(2012) Hazuki E. Miwa et al.   GLYCOCONJUGATE JOURNAL

Loss and Recovery of Mgat3 and GnT-III Mediated E-cadherin N-glycosylation Is a Mechanism Involved in Epithelial-Mesenchymal-Epithelial Transitions

(2012) Salomé S. Pinho et al.   PLoS One

IGF-1 increases invasive potential of MCF 7 breast cancer cells and induces activation of latent TGF-β1 resulting in epithelial to mesenchymal transition

(2011) Logan A Walsh et al.   Cell Communication and Signaling

18FDG-PET Predicts Pharmacodynamic Response to OSI-906, a Dual IGF-1R/IR Inhibitor, in Preclinical Mouse Models of Lung Cancer

(2011) E. T. McKinley et al.   CLINICAL CANCER RESEARCH

E-cadherin impairment increases cell survival through Notch-dependent upregulation of Bcl-2

(2011) António Carlos Ferreira et al.   HUMAN MOLECULAR GENETICS

Epithelial-Mesenchymal Transition Predicts Sensitivity to the Dual IGF-1R/IR Inhibitor OSI-906 in Hepatocellular Carcinoma Cell Lines

(2011) H. Zhao et al.   MOLECULAR CANCER THERAPEUTICS

Inhibition of IGF-1 Signaling by Genistein: Modulation of E-Cadherin Expression and Downregulation of β-Catenin Signaling in Hormone Refractory PC-3 Prostate Cancer Cells

(2011) Joomin Lee et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Inhibition of N-linked glycosylation by tunicamycin induces E-cadherin-mediated cell–cell adhesion and inhibits cell proliferation in undifferentiated human colon cancer cells

(2010) Julio Cesar Madureira de Freitas Junior et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

The Bisecting GlcNAc on N-Glycans Inhibits Growth Factor Signaling and Retards Mammary Tumor Progression

(2010) Y. Song et al.   CANCER RESEARCH

Modulation of E-cadherin function and dysfunction by N-glycosylation

(2010) Salomé S. Pinho et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

A systems view of epithelial–mesenchymal transition signaling states

(2010) Stuart Thomson et al.   CLINICAL & EXPERIMENTAL METASTASIS

Hypoglycosylated E-cadherin promotes the assembly of tight junctions through the recruitment of PP2A to adherens junctions

(2010) Mihai Nita-Lazar et al.   EXPERIMENTAL CELL RESEARCH

Role of E-cadherin N-glycosylation profile in a mammary tumor model

(2009) Salomé S. Pinho et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Quantification of Epigenetic and Genetic 2nd Hits in CDH1 During Hereditary Diffuse Gastric Cancer Syndrome Progression

(2009) Carla Oliveira et al.   GASTROENTEROLOGY

The role of N-acetylglucosaminyltransferase III and V in the post-transcriptional modifications of E-cadherin

(2009) S. S. Pinho et al.   HUMAN MOLECULAR GENETICS

IGF and Insulin Receptor Signaling in Breast Cancer

(2008) Antonino Belfiore et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA