标题
RNA: a double-edged sword in genome maintenance
作者
关键词
-
出版物
NATURE REVIEWS GENETICS
Volume -, Issue -, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2020-08-06
DOI
10.1038/s41576-020-0263-7
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Our Conflict with Transposable Elements and Its Implications for Human Disease
- (2020) Kathleen H. Burns Annual Review of Pathology-Mechanisms of Disease
- The roles of RNA in DNA double-strand break repair
- (2020) Aldo S. Bader et al. BRITISH JOURNAL OF CANCER
- 53BP1: a DSB escort
- (2020) Zachary Mirman et al. GENES & DEVELOPMENT
- One, No One, and One Hundred Thousand: The Many Forms of Ribonucleotides in DNA
- (2020) Giulia Maria Nava et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Ultra-Deep Coverage Single-Molecule R-loop Footprinting Reveals Principles of R-loop Formation
- (2020) Maika Malig et al. JOURNAL OF MOLECULAR BIOLOGY
- The repertoire of mutational signatures in human cancer
- (2020) Ludmil B. Alexandrov et al. NATURE
- Conserved chromosomal functions of RNA interference
- (2020) Michael J. Gutbrod et al. NATURE REVIEWS GENETICS
- Regulatory R-loops as facilitators of gene expression and genome stability
- (2020) Christof Niehrs et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Regulation of long non-coding RNAs and genome dynamics by the RNA surveillance machinery
- (2020) Lekha Nair et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The antitumorigenic roles of BRCA1–BARD1 in DNA repair and replication
- (2020) Madalena Tarsounas et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Cell fitness screens reveal a conflict between LINE-1 retrotransposition and DNA replication
- (2020) Daniel Ardeljan et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- BRCA1 and S phase DNA repair pathways restrict LINE-1 retrotransposition in human cells
- (2020) Paolo Mita et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Intrinsically disordered protein RBM14 plays a role in generation of RNA:DNA hybrids at double-strand break sites
- (2020) Yumi Jang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Transcriptional Regulation at DSBs: Mechanisms and Consequences
- (2020) Feras E. Machour et al. TRENDS IN GENETICS
- Suppressing proteasome mediated processing of Topoisomerase II DNA-protein complexes preserves genome integrity
- (2020) Nicholas Sciascia et al. eLife
- Physiological and Pathological Roles of RAD52 at DNA Replication Forks
- (2020) Eva Malacaria et al. Cancers
- Ubiquitination of DNA Damage-Stalled RNAPII Promotes Transcription-Coupled Repair
- (2020) Yuka Nakazawa et al. CELL
- Regulation of the RNAPII Pool Is Integral to the DNA Damage Response
- (2020) Ana Tufegdžić Vidaković et al. CELL
- m6A-binding YTHDF proteins promote stress granule formation
- (2020) Ye Fu et al. Nature Chemical Biology
- DNA:RNA hybrids form at DNA double-strand breaks in transcriptionally active loci
- (2020) Aldo S. Bader et al. Cell Death & Disease
- Hypermutation in single-stranded DNA
- (2020) Natalie Saini et al. DNA REPAIR
- Genomic stability, anti-inflammatory phenotype, and up-regulation of the RNAseH2 in cells from centenarians
- (2019) Gianluca Storci et al. CELL DEATH AND DIFFERENTIATION
- RNase H1 directs origin-specific initiation of DNA replication in human mitochondria
- (2019) Viktor Posse et al. PLoS Genetics
- Single-molecule imaging of transcription at damaged chromatin
- (2019) Alexandra C. Vítor et al. Science Advances
- Interplay between DNA sequence and negative superhelicity drives R-loop structures
- (2019) Robert Stolz et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Genome-wide colocalization of RNA–DNA interactions and fusion RNA pairs
- (2019) Zhangming Yan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Precise gene replacement in rice by RNA transcript-templated homologous recombination
- (2019) Shaoya Li et al. NATURE BIOTECHNOLOGY
- Recruitment of BRCA1 limits MYCN-driven accumulation of stalled RNA polymerase
- (2019) Steffi Herold et al. NATURE
- R-Loops as Cellular Regulators and Genomic Threats
- (2019) Madzia P. Crossley et al. MOLECULAR CELL
- Human DNA polymerase η has reverse transcriptase activity in cellular environments
- (2019) Yan Su et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Regulation of R-loops and genome instability in Fanconi anemia
- (2019) Yusuke Okamoto et al. JOURNAL OF BIOCHEMISTRY
- Transcription-mediated replication hindrance: a major driver of genome instability
- (2019) Belén Gómez-González et al. GENES & DEVELOPMENT
- The mitochondrial R-loop
- (2019) Ian J Holt NUCLEIC ACIDS RESEARCH
- The Jekyll and Hyde character of RNase H1 and its multiple roles in mitochondrial DNA metabolism
- (2019) Ian J. Holt DNA REPAIR
- How do mutations affecting the breast cancer genes BRCA1 and BRCA2 cause cancer susceptibility?
- (2019) Ashok R. Venkitaraman DNA REPAIR
- RNases H: Structure and mechanism
- (2019) Malwina Hyjek et al. DNA REPAIR
- Non-canonical DNA/RNA structures during Transcription-Coupled Double-Strand Break Repair: Roadblocks or Bona fide repair intermediates?
- (2019) Nadine Puget et al. DNA REPAIR
- Phase separation of 53 BP 1 determines liquid‐like behavior of DNA repair compartments
- (2019) Sinan Kilic et al. EMBO JOURNAL
- The DNA damage response acts as a safeguard against harmful DNA–RNA hybrids of different origins
- (2019) Sonia Barroso et al. EMBO REPORTS
- Mammalian DNA Polymerase Kappa Activity and Specificity
- (2019) Hannah R. Stern et al. MOLECULES
- m6A enhances the phase separation potential of mRNA
- (2019) Ryan J. Ries et al. NATURE
- Chromatin-associated RNAs as facilitators of functional genomic interactions
- (2019) Xiao Li et al. NATURE REVIEWS GENETICS
- EXOSC10 is required for RPA assembly and controlled DNA end resection at DNA double-strand breaks
- (2019) Judit Domingo-Prim et al. Nature Communications
- Emerging Roles of RAD52 in Genome Maintenance
- (2019) Manisha Jalan et al. Cancers
- Multivalent m6A motifs promote phase separation of YTHDF proteins
- (2019) Yifei Gao et al. CELL RESEARCH
- Current insights into the mechanism of mammalian immunoglobulin class switch recombination
- (2019) Kefei Yu et al. CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Distinct Classes of Chromatin Loops Revealed by Deletion of an RNA-Binding Region in CTCF
- (2019) Anders S. Hansen et al. MOLECULAR CELL
- RNA Interactions Are Essential for CTCF-Mediated Genome Organization
- (2019) Ricardo Saldaña-Meyer et al. MOLECULAR CELL
- Functional transcription promoters at DNA double-strand breaks mediate RNA-driven phase separation of damage-response factors
- (2019) Fabio Pessina et al. NATURE CELL BIOLOGY
- R Loops: From Physiological to Pathological Roles
- (2019) Tatiana García-Muse et al. CELL
- m6A promotes R-loop formation to facilitate transcription termination
- (2019) Xin Yang et al. CELL RESEARCH
- Bon voyage: A transcriptional journey around DNA breaks
- (2019) Pierre Caron et al. DNA REPAIR
- Regional Gene Repression by DNA Double-Strand Breaks in G1 Phase Cells
- (2019) Caitlin E. Purman et al. MOLECULAR AND CELLULAR BIOLOGY
- R-Loops Promote Antisense Transcription across the Mammalian Genome
- (2019) Sue Mei Tan-Wong et al. MOLECULAR CELL
- ATR Protects the Genome against R Loops through a MUS81-Triggered Feedback Loop
- (2019) Dominick A. Matos et al. MOLECULAR CELL
- Processing of a single ribonucleotide embedded into DNA by human nucleotide excision repair and DNA polymerase η
- (2019) Akira Sassa et al. Scientific Reports
- Mapping Native R-Loops Genome-wide Using a Targeted Nuclease Approach
- (2019) Qingqing Yan et al. Cell Reports
- RAD52 Functions in Homologous Recombination and Its Importance on Genomic Integrity Maintenance and Cancer Therapy
- (2019) Augusto Nogueira et al. Cancers
- Retroelement Insertion in a CRISPR/Cas9 Editing Site in the Early Embryo Intensifies Genetic Mosaicism
- (2019) Jeehyun Jeon et al. Frontiers in Cell and Developmental Biology
- ZPR1 prevents R-loop accumulation, upregulates SMN2 expression and rescues spinal muscular atrophy
- (2019) Annapoorna Kannan et al. BRAIN
- Molecular and physiological consequences of faulty eukaryotic ribonucleotide excision repair
- (2019) Vanessa Kellner et al. EMBO JOURNAL
- N6-methyladenosine regulates the stability of RNA:DNA hybrids in human cells
- (2019) Abdulkadir Abakir et al. NATURE GENETICS
- The Biogenesis and Precise Control of RNA m6A Methylation
- (2019) Huilin Huang et al. TRENDS IN GENETICS
- From “Cellular” RNA to “Smart” RNA: Multiple Roles of RNA in Genome Stability and Beyond
- (2018) Flavia Michelini et al. CHEMICAL REVIEWS
- Mammalian transposable elements and their impacts on genome evolution
- (2018) Roy N. Platt et al. CHROMOSOME RESEARCH
- Transposable elements: genome innovation, chromosome diversity, and centromere conflict
- (2018) Savannah J. Klein et al. CHROMOSOME RESEARCH
- R-loops: targets for nuclease cleavage and repeat instability
- (2018) Catherine H. Freudenreich CURRENT GENETICS
- RNase H eliminates R‐loops that disrupt DNA replication but is nonessential for efficient DSB repair
- (2018) Hongchang Zhao et al. EMBO REPORTS
- DNA:RNA hybrids at telomeres - when it is better to be out of the (R) loop
- (2018) Shir Toubiana et al. FEBS Journal
- Yra1-bound RNA–DNA hybrids cause orientation-independent transcription–replication collisions and telomere instability
- (2018) María García-Rubio et al. GENES & DEVELOPMENT
- Short Telomere Syndromes in Clinical Practice: Bridging Bench and Bedside
- (2018) Abhishek A. Mangaonkar et al. MAYO CLINIC PROCEEDINGS
- The Augmented R-Loop Is a Unifying Mechanism for Myelodysplastic Syndromes Induced by High-Risk Splicing Factor Mutations
- (2018) Liang Chen et al. MOLECULAR CELL
- Senataxin Mutation Reveals How R-Loops Promote Transcription by Blocking DNA Methylation at Gene Promoters
- (2018) Christopher Grunseich et al. MOLECULAR CELL
- Heterochromatin-Encoded Satellite RNAs Induce Breast Cancer
- (2018) Quan Zhu et al. MOLECULAR CELL
- Controlling nuclear RNA levels
- (2018) Manfred Schmid et al. NATURE REVIEWS GENETICS
- Mechanism of 53BP1 activity regulation by RNA-binding TIRR and a designer protein
- (2018) Maria Victoria Botuyan et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Initiation of homologous recombination at DNA nicks
- (2018) Nancy Maizels et al. NUCLEIC ACIDS RESEARCH
- Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation
- (2018) Marcel Naumann et al. Nature Communications
- Mechanism of 53BP1 activity regulation by RNA-binding TIRR and a designer protein
- (2018) Maria Victoria Botuyan et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- RNA/DNA Hybrid Interactome Identifies DXH9 as a Molecular Player in Transcriptional Termination and R-Loop-Associated DNA Damage
- (2018) Agnese Cristini et al. Cell Reports
- BRCA2 Regulates Transcription Elongation by RNA Polymerase II to Prevent R-Loop Accumulation
- (2018) Mahmud K.K. Shivji et al. Cell Reports
- Surveillance-ready transcription: nuclear RNA decay as a default fate
- (2018) Stefan Bresson et al. Open Biology
- Chromatin-associated RNA sequencing (ChAR-seq) maps genome-wide RNA-to-DNA contacts
- (2018) Jason C Bell et al. eLife
- Human Rad52 Promotes XPG-Mediated R-loop Processing to Initiate Transcription-Associated Homologous Recombination Repair
- (2018) Takaaki Yasuhara et al. CELL
- R-loop generation during transcription: Formation, processing and cellular outcomes
- (2018) Boris P. Belotserkovskii et al. DNA REPAIR
- Human proteins that interact with RNA/DNA hybrids
- (2018) Isabel X. Wang et al. GENOME RESEARCH
- Genome-wide Map of R-Loop-Induced Damage Reveals How a Subset of R-Loops Contributes to Genomic Instability
- (2018) Lorenzo Costantino et al. MOLECULAR CELL
- R-Loops in Motor Neuron Diseases
- (2018) Martina G. L. Perego et al. MOLECULAR NEUROBIOLOGY
- Mitochondrial double-stranded RNA triggers antiviral signalling in humans
- (2018) Ashish Dhir et al. NATURE
- EWS–FLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma
- (2018) Aparna Gorthi et al. NATURE
- CRISPR screens identify genomic ribonucleotides as a source of PARP-trapping lesions
- (2018) Michal Zimmermann et al. NATURE
- Ribonucleotide incorporation enables repair of chromosome breaks by nonhomologous end joining
- (2018) John M. Pryor et al. SCIENCE
- piRNA-Guided Genome Defense: From Biogenesis to Silencing
- (2018) Benjamin Czech et al. Annual Review of Genetics
- Somatic APP gene recombination in Alzheimer’s disease and normal neurons
- (2018) Ming-Hsiang Lee et al. NATURE
- PIWI-interacting RNAs: small RNAs with big functions
- (2018) Deniz M. Ozata et al. NATURE REVIEWS GENETICS
- Next-generation sequencing reveals two populations of damage-induced small RNAs at endogenous DNA double-strand breaks
- (2018) Franziska Bonath et al. NUCLEIC ACIDS RESEARCH
- RNA-mediated gene fusion in mammalian cells
- (2018) Sachin Kumar Gupta et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Human mitochondrial degradosome prevents harmful mitochondrial R loops and mitochondrial genome instability
- (2018) Sonia Silva et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- BRCA2 controls DNA:RNA hybrid level at DSBs by mediating RNase H2 recruitment
- (2018) Giuseppina D’Alessandro et al. Nature Communications
- Two RNase H2 Mutants with Differential rNMP Processing Activity Reveal a Threshold of Ribonucleotide Tolerance for Embryonic Development
- (2018) Ryo Uehara et al. Cell Reports
- Genome integrity and disease prevention in the nervous system
- (2017) Peter J. McKinnon GENES & DEVELOPMENT
- Transposable Elements in Human Cancer: Causes and Consequences of Deregulation
- (2017) Sumadi Anwar et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- RAD52 is required for RNA-templated recombination repair in post-mitotic neurons
- (2017) Starr Welty et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Transcription-Coupled DNA Double-Strand Break Repair: Active Genes Need Special Care
- (2017) Aline Marnef et al. JOURNAL OF MOLECULAR BIOLOGY
- R Loops and Links to Human Disease
- (2017) Patricia Richard et al. JOURNAL OF MOLECULAR BIOLOGY
- Functions of Replication Protein A as a Sensor of R Loops and a Regulator of RNaseH1
- (2017) Hai Dang Nguyen et al. MOLECULAR CELL
- R-ChIP Using Inactive RNase H Reveals Dynamic Coupling of R-loops with Transcriptional Pausing at Gene Promoters
- (2017) Liang Chen et al. MOLECULAR CELL
- Histone Mutants Separate R Loop Formation from Genome Instability Induction
- (2017) Desiré García-Pichardo et al. MOLECULAR CELL
- Rad52 Inverse Strand Exchange Drives RNA-Templated DNA Double-Strand Break Repair
- (2017) Olga M. Mazina et al. MOLECULAR CELL
- Introns Protect Eukaryotic Genomes from Transcription-Associated Genetic Instability
- (2017) Amandine Bonnet et al. MOLECULAR CELL
- RNA m6A methylation regulates the ultraviolet-induced DNA damage response
- (2017) Yang Xiang et al. NATURE
- TIRR regulates 53BP1 by masking its histone methyl-lysine binding function
- (2017) Pascal Drané et al. NATURE
- GRID-seq reveals the global RNA–chromatin interactome
- (2017) Xiao Li et al. NATURE BIOTECHNOLOGY
- Damage-induced lncRNAs control the DNA damage response through interaction with DDRNAs at individual double-strand breaks
- (2017) Flavia Michelini et al. NATURE CELL BIOLOGY
- DNA–RNA hybrids: the risks of DNA breakage during transcription
- (2017) Andrés Aguilera et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Mobile DNA in Health and Disease
- (2017) Haig H. Kazazian et al. NEW ENGLAND JOURNAL OF MEDICINE
- Abasic and oxidized ribonucleotides embedded in DNA are processed by human APE1 and not by RNase H2
- (2017) Matilde Clarissa Malfatti et al. NUCLEIC ACIDS RESEARCH
- Aberrant ribonucleotide incorporation and multiple deletions in mitochondrial DNA of the murine MPV17 disease model
- (2017) Chloe F. Moss et al. NUCLEIC ACIDS RESEARCH
- Physical proximity of chromatin to nuclear pores prevents harmful R loop accumulation contributing to maintain genome stability
- (2017) Francisco García-Benítez et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The RNA exosome and RNA exosome-linked disease
- (2017) Derrick J. Morton et al. RNA
- A mitosis-specific and R loop–driven ATR pathway promotes faithful chromosome segregation
- (2017) Lilian Kabeche et al. SCIENCE
- Telomeres in ICF syndrome cells are vulnerable to DNA damage due to elevated DNA:RNA hybrids
- (2017) Shira Sagie et al. Nature Communications
- The emergence of piRNAs against transposon invasion to preserve mammalian genome integrity
- (2017) Christina Ernst et al. Nature Communications
- DNA–RNA hybrids: the risks of DNA breakage during transcription
- (2017) Andrés Aguilera et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Nucleotide pools dictate the identity and frequency of ribonucleotide incorporation in mitochondrial DNA
- (2017) Anna-Karin Berglund et al. PLoS Genetics
- Defining the location of promoter-associated R-loops at near-nucleotide resolution using bisDRIP-seq
- (2017) Jason G Dumelie et al. eLife
- Repetitive DNA loci and their modulation by the non-canonical nucleic acid structures R-loops and G-quadruplexes
- (2017) Amanda C. Hall et al. Nucleus
- The Role of Replication-Associated Repair Factors on R-Loops
- (2017) et al. Genes
- Replication Fork Protection Factors Controlling R-Loop Bypass and Suppression
- (2017) Emily Chang et al. Genes
- Repetitive DNA loci and their modulation by the non-canonical nucleic acid structures R-loops and G-quadruplexes
- (2017) Amanda C. Hall et al. Nucleus
- Efficient Generation of diRNAs Requires Components in the Posttranscriptional Gene Silencing Pathway
- (2017) Daisuke Miki et al. Scientific Reports
- Polyadenylation and degradation of RNA in the mitochondria
- (2016) Shiri Levy et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- The roles of the exoribonucleases DIS3L2 and XRN1 in human disease
- (2016) Amy L. Pashler et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Small RNAs Recruit Chromatin-Modifying Enzymes MMSET and Tip60 to Reconfigure Damaged DNA upon Double-Strand Break and Facilitate Repair
- (2016) Qinhong Wang et al. CANCER RESEARCH
- Transient RNA-DNA Hybrids Are Required for Efficient Double-Strand Break Repair
- (2016) Corina Ohle et al. CELL
- Topoisomerase I‐mediated cleavage at unrepaired ribonucleotides generates DNA double‐strand breaks
- (2016) Shar‐yin N Huang et al. EMBO JOURNAL
- Ribonuclease H2 mutations induce a cGAS/STING‐dependent innate immune response
- (2016) Karen J Mackenzie et al. EMBO JOURNAL
- S1-DRIP-seq identifies high expression and polyA tracts as major contributors to R-loop formation
- (2016) Lamia Wahba et al. GENES & DEVELOPMENT
- DICER, DROSHA and DNA damage response RNAs are necessary for the secondary recruitment of DNA damage response factors
- (2016) Sofia Francia et al. JOURNAL OF CELL SCIENCE
- RNase H2 catalytic core Aicardi-Goutières syndrome–related mutant invokes cGAS–STING innate immune-sensing pathway in mice
- (2016) Vladislav Pokatayev et al. JOURNAL OF EXPERIMENTAL MEDICINE
- DEAD Box 1 Facilitates Removal of RNA and Homologous Recombination at DNA Double-Strand Breaks
- (2016) Lei Li et al. MOLECULAR AND CELLULAR BIOLOGY
- Prevalent, Dynamic, and Conserved R-Loop Structures Associate with Specific Epigenomic Signatures in Mammals
- (2016) Lionel A. Sanz et al. MOLECULAR CELL
- The TIP60 Complex Regulates Bivalent Chromatin Recognition by 53BP1 through Direct H4K20me Binding and H2AK15 Acetylation
- (2016) Karine Jacquet et al. MOLECULAR CELL
- Processing ribonucleotides incorporated during eukaryotic DNA replication
- (2016) Jessica S. Williams et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The regulation and functions of the nuclear RNA exosome complex
- (2016) Cornelia Kilchert et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- ViableRNaseH1knockout mice show RNaseH1 is essential for R loop processing, mitochondrial and liver function
- (2016) Walt F. Lima et al. NUCLEIC ACIDS RESEARCH
- Pathological ribonuclease H1 causes R-loop depletion and aberrant DNA segregation in mitochondria
- (2016) Gokhan Akman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Balancing Act of Ribonucleotides in DNA
- (2016) Susana M. Cerritelli et al. TRENDS IN BIOCHEMICAL SCIENCES
- Nascent Connections: R-Loops and Chromatin Patterning
- (2016) Frédéric Chédin TRENDS IN GENETICS
- Telomeric RNAs are essential to maintain telomeres
- (2016) Juan José Montero et al. Nature Communications
- Classical non-homologous end-joining pathway utilizes nascent RNA for error-free double-strand break repair of transcribed genes
- (2016) Anirban Chakraborty et al. Nature Communications
- Increased global transcription activity as a mechanism of replication stress in cancer
- (2016) Panagiotis Kotsantis et al. Nature Communications
- Replication landscape of the human genome
- (2016) Nataliya Petryk et al. Nature Communications
- Impact of ribonucleotide incorporation by DNA polymerases β and λ on oxidative base excision repair
- (2016) Emmanuele Crespan et al. Nature Communications
- RNase H enables efficient repair of R-loop induced DNA damage
- (2016) Jeremy D Amon et al. eLife
- Co-transcriptional R-loops are the main cause of estrogen-induced DNA damage
- (2016) Caroline Townsend Stork et al. eLife
- Restricting retrotransposons: a review
- (2016) John L. Goodier Mobile DNA
- Reappearance from Obscurity: Mammalian Rad52 in Homologous Recombination
- (2016) Kritika Hanamshet et al. Genes
- RNASEH1 Mutations Impair mtDNA Replication and Cause Adult-Onset Mitochondrial Encephalomyopathy
- (2015) Aurelio Reyes et al. AMERICAN JOURNAL OF HUMAN GENETICS
- PIWI-Interacting RNA: Its Biogenesis and Functions
- (2015) Yuka W. Iwasaki et al. Annual Review of Biochemistry
- A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation
- (2015) Avinash Patel et al. CELL
- RNA Exosome-Regulated Long Non-Coding RNA Transcription Controls Super-Enhancer Activity
- (2015) Evangelos Pefanis et al. CELL
- Redundancy in ribonucleotide excision repair: Competition, compensation, and cooperation
- (2015) Alexandra Vaisman et al. DNA REPAIR
- Error-free and mutagenic processing of topoisomerase 1-provoked damage at genomic ribonucleotides
- (2015) J. L. Sparks et al. EMBO JOURNAL
- Nascent RNA folding mitigates transcription-associated mutagenesis
- (2015) Xiaoshu Chen et al. GENOME RESEARCH
- Analysis of Ribonucleotide Removal from DNA by Human Nucleotide Excision Repair
- (2015) Laura A. Lindsey-Boltz et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Formation and Repair of Mismatches Containing Ribonucleotides and Oxidized Bases at Repeated DNA Sequences
- (2015) Piera Cilli et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Fanconi Anemia Pathway Maintains Genome Stability by Coordinating Replication and Transcription
- (2015) Rebekka A. Schwab et al. MOLECULAR CELL
- BRCA1 Recruitment to Transcriptional Pause Sites Is Required for R-Loop-Driven DNA Damage Repair
- (2015) Elodie Hatchi et al. MOLECULAR CELL
- The core spliceosome as target and effector of non-canonical ATM signalling
- (2015) Maria Tresini et al. NATURE
- Ribose-seq: global mapping of ribonucleotides embedded in genomic DNA
- (2015) Kyung Duk Koh et al. NATURE METHODS
- Role for RNA:DNA hybrids in origin-independent replication priming in a eukaryotic system
- (2015) Ruth Stuckey et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Primer retention owing to the absence of RNase H1 is catastrophic for mitochondrial DNA replication
- (2015) J. Bradley Holmes et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- DNA damage during the G0/G1 phase triggers RNA-templated, Cockayne syndrome B-dependent homologous recombination
- (2015) Leizhen Wei et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Transcript RNA supports precise repair of its own DNA gene
- (2015) Havva Keskin et al. RNA Biology
- RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships
- (2015) Julie Nadel et al. Epigenetics & Chromatin
- Liquid demixing of intrinsically disordered proteins is seeded by poly(ADP-ribose)
- (2015) Matthias Altmeyer et al. Nature Communications
- Genome-wide DNA hypomethylation and RNA:DNA hybrid accumulation in Aicardi–Goutières syndrome
- (2015) Yoong Wearn Lim et al. eLife
- Ago2 facilitates Rad51 recruitment and DNA double-strand break repair by homologous recombination
- (2014) Min Gao et al. CELL RESEARCH
- Reduction of hRNase H2 activity in Aicardi–Goutières syndrome cells leads to replication stress and genome instability
- (2014) Sara Pizzi et al. HUMAN MOLECULAR GENETICS
- Defective removal of ribonucleotides from DNA promotes systemic autoimmunity
- (2014) Claudia Günther et al. JOURNAL OF CLINICAL INVESTIGATION
- Transcription-Coupled Nucleotide Excision Repair Factors Promote R-Loop-Induced Genome Instability
- (2014) Julie Sollier et al. MOLECULAR CELL
- RNA intrusions change DNA elastic properties and structure
- (2014) Hsiang-Chih Chiu et al. Nanoscale
- BRCA2 prevents R-loop accumulation and associates with TREX-2 mRNA export factor PCID2
- (2014) Vaibhav Bhatia et al. NATURE
- Transcript-RNA-templated DNA recombination and repair
- (2014) Havva Keskin et al. NATURE
- Repair of DNA double-strand breaks by templated nucleotide sequence insertions derived from distant regions of the genome
- (2014) M. Onozawa et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Promoter-Bound Trinucleotide Repeat mRNA Drives Epigenetic Silencing in Fragile X Syndrome
- (2014) D. Colak et al. SCIENCE
- RNaseH1 regulates TERRA-telomeric DNA hybrids and telomere maintenance in ALT tumour cells
- (2014) Rajika Arora et al. Nature Communications
- Ribonucleotides as nucleotide excision repair substrates
- (2013) Yuqin Cai et al. DNA REPAIR
- GC skew at the 5' and 3' ends of human genes links R-loop formation to epigenetic regulation and transcription termination
- (2013) P. A. Ginno et al. GENOME RESEARCH
- Ribonucleotides Are Signals for Mismatch Repair of Leading-Strand Replication Errors
- (2013) Scott A. Lujan et al. MOLECULAR CELL
- R Loops Are Linked to Histone H3 S10 Phosphorylation and Chromatin Condensation
- (2013) Maikel Castellano-Pozo et al. MOLECULAR CELL
- Interaction of FUS and HDAC1 regulates DNA damage response and repair in neurons
- (2013) Wen-Yuan Wang et al. NATURE NEUROSCIENCE
- Acetylation limits 53BP1 association with damaged chromatin to promote homologous recombination
- (2013) Jiangbo Tang et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- RNase H2 roles in genome integrity revealed by unlinking its activities
- (2013) Hyongi Chon et al. NUCLEIC ACIDS RESEARCH
- R-Loop Stabilization Represses Antisense Transcription at the Arabidopsis FLC Locus
- (2013) Q. Sun et al. SCIENCE
- The homologous recombination machinery modulates the formation of RNA–DNA hybrids and associated chromosome instability
- (2013) Lamia Wahba et al. eLife
- Enzymatic Removal of Ribonucleotides from DNA Is Essential for Mammalian Genome Integrity and Development
- (2012) Martin A.M. Reijns et al. CELL
- A Role for Small RNAs in DNA Double-Strand Break Repair
- (2012) Wei Wei et al. CELL
- Nuclear architecture by RNA
- (2012) Maïwen Caudron-Herger et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Ribonucleotide incorporation, proofreading and bypass by human DNA polymerase δ
- (2012) Anders R. Clausen et al. DNA REPAIR
- Human DNA Polymerase ϵ Is Able to Efficiently Extend from Multiple Consecutive Ribonucleotides
- (2012) A. Yasemin Göksenin et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Frequent Incorporation of Ribonucleotides during HIV-1 Reverse Transcription and Their Attenuated Repair in Macrophages
- (2012) Edward M. Kennedy et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mammalian RNase H2 removes ribonucleotides from DNA to maintain genome integrity
- (2012) Bjoern Hiller et al. JOURNAL OF EXPERIMENTAL MEDICINE
- RNase H and Postreplication Repair Protect Cells from Ribonucleotides Incorporated in DNA
- (2012) Federico Lazzaro et al. MOLECULAR CELL
- R-Loop Formation Is a Distinctive Characteristic of Unmethylated Human CpG Island Promoters
- (2012) Paul A. Ginno et al. MOLECULAR CELL
- Site-specific DICER and DROSHA RNA products control the DNA-damage response
- (2012) Sofia Francia et al. NATURE
- A small RNA response at DNA ends in Drosophila
- (2012) Katharina M. Michalik et al. NUCLEIC ACIDS RESEARCH
- Telomeres and disease: Enter TERRA
- (2012) André Maicher et al. RNA Biology
- TERRA Promotes Telomere Shortening through Exonuclease 1–Mediated Resection of Chromosome Ends
- (2012) Verena Pfeiffer et al. PLoS Genetics
- Anchoring Nascent RNA to the DNA Template Could Interfere with Transcription
- (2011) Boris P. Belotserkovskii et al. BIOPHYSICAL JOURNAL
- R-loop-mediated genomic instability is caused by impairment of replication fork progression
- (2011) W. Gan et al. GENES & DEVELOPMENT
- Ribonucleotide Discrimination and Reverse Transcription by the Human Mitochondrial DNA Polymerase
- (2011) Rajesh Kasiviswanathan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Collisions between Replication and Transcription Complexes Cause Common Fragile Site Instability at the Longest Human Genes
- (2011) Anne Helmrich et al. MOLECULAR CELL
- RNase H and Multiple RNA Biogenesis Factors Cooperate to Prevent RNA:DNA Hybrids from Generating Genome Instability
- (2011) Lamia Wahba et al. MOLECULAR CELL
- Human Senataxin Resolves RNA/DNA Hybrids Formed at Transcriptional Pause Sites to Promote Xrn2-Dependent Termination
- (2011) Konstantina Skourti-Stathaki et al. MOLECULAR CELL
- RNA-driven genetic changes in bacteria and in human cells
- (2011) Ying Shen et al. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
- BRCA1 tumour suppression occurs via heterochromatin-mediated silencing
- (2011) Quan Zhu et al. NATURE
- Quantitative model of R-loop forming structures reveals a novel level of RNA-DNA interactome complexity
- (2011) T. Wongsurawat et al. NUCLEIC ACIDS RESEARCH
- The NF1 Gene Contains Hotspots for L1 Endonuclease-Dependent De Novo Insertion
- (2011) Katharina Wimmer et al. PLoS Genetics
- Division of labor: DNA repair and the cell cycle specific functions of the Mre11 complex
- (2010) Carrie A. Adelman et al. CELL CYCLE
- Characterization of the RNA content of chromatin
- (2010) T. Mondal et al. GENOME RESEARCH
- Genome instability due to ribonucleotide incorporation into DNA
- (2010) Stephanie A Nick McElhinny et al. Nature Chemical Biology
- Abundant ribonucleotide incorporation into DNA by yeast replicative polymerases
- (2010) S. A. Nick McElhinny et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Many Pathways of RNA Degradation
- (2009) Jonathan Houseley et al. CELL
- Ataxia telangiectasia mutated activation by transcription- and topoisomerase I-induced DNA double-strand breaks
- (2009) Olivier Sordet et al. EMBO REPORTS
- Ribonuclease H: the enzymes in eukaryotes
- (2009) Susana M. Cerritelli et al. FEBS Journal
- The DNA-damage response in human biology and disease
- (2009) Stephen P. Jackson et al. NATURE
- The emerging role of nuclear architecture in DNA repair and genome maintenance
- (2009) Tom Misteli et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- CpG-island promoters drive transcription of human telomeres
- (2009) S. G. Nergadze et al. RNA
- The Rat1p 5′ to 3′ Exonuclease Degrades Telomeric Repeat-Containing RNA and Promotes Telomere Elongation in Saccharomyces cerevisiae
- (2008) Brian Luke et al. MOLECULAR CELL
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