Two RNase H2 Mutants with Differential rNMP Processing Activity Reveal a Threshold of Ribonucleotide Tolerance for Embryonic Development

出版年份 2018 全文链接

标题

作者

关键词

ribonuclease H2, RNase H2, genome integrity, innate immunity, embedded ribonucleotides, p53 damage response, DNA damage, mouse development, Aicardi-Goutières syndrome, AGS

出版物

Cell Reports

Volume 25, Issue 5, Pages 1135-1145.e5

出版商

Elsevier BV

发表日期

2018-10-30

DOI

10.1016/j.celrep.2018.10.019

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