标题
Emerging roles and the regulation of aerobic glycolysis in hepatocellular carcinoma
作者
关键词
-
出版物
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
Volume 39, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2020-07-06
DOI
10.1186/s13046-020-01629-4
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- New systemic agents for hepatocellular carcinoma
- (2020) Johann von Felden CURRENT OPINION IN GASTROENTEROLOGY
- Impact of Immune Response on Outcomes in Hepatocellular Carcinoma: Association with Vascular Formation
- (2020) Shinji Itoh et al. HEPATOLOGY
- Simvastatin re-sensitizes hepatocellular carcinoma cells to sorafenib by inhibiting HIF-1α/PPAR-γ/PKM2-mediated glycolysis
- (2020) Jiao Feng et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Molecular therapies for HCC: Looking outside the box
- (2020) Sandrine Faivre et al. JOURNAL OF HEPATOLOGY
- Androgen Receptor Stimulates Hexokinase 2 and Induces Glycolysis by PKA/CREB Signaling in Hepatocellular Carcinoma
- (2020) R. F. Sun et al. DIGESTIVE DISEASES AND SCIENCES
- IMbrave 050: a Phase III trial of atezolizumab plus bevacizumab in high-risk hepatocellular carcinoma after curative resection or ablation
- (2020) Stephen P Hack et al. Future Oncology
- Atezolizumab plus Bevacizumab in Unresectable Hepatocellular Carcinoma
- (2020) Richard S. Finn et al. NEW ENGLAND JOURNAL OF MEDICINE
- Metabolic Heterogeneity of Cancer Cells: An Interplay between HIF-1, GLUTs, and AMPK
- (2020) Nurbubu T. Moldogazieva et al. Cancers
- Scientific Rationale for Combined Immunotherapy with PD-1/PD-L1 Antibodies and VEGF Inhibitors in Advanced Hepatocellular Carcinoma
- (2020) Masatoshi Kudo Cancers
- Critical role of AMPK in redox regulation under glucose starvation
- (2019) Yi Ren et al. Redox Biology
- FOXK1 and FOXK2 regulate aerobic glycolysis
- (2019) Valentina Sukonina et al. NATURE
- Targeting the ROS/PI3K/AKT/HIF‐1α/HK2 axis of breast cancer cells: Combined administration of Polydatin and 2‐Deoxy‐d‐glucose
- (2019) Tao Zhang et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- The Warburg effect: essential part of metabolic reprogramming and central contributor to cancer progression
- (2019) Peter Vaupel et al. INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
- Long Noncoding RNA MALAT1 regulates cancer glucose metabolism by enhancing mTOR-mediated translation of TCF7L2
- (2019) Pushkar Malakar et al. CANCER RESEARCH
- Circular RNA MAT2B Promotes Glycolysis and Malignancy of Hepatocellular Carcinoma Through the miR‐338‐3p/PKM2 Axis Under Hypoxic Stress
- (2019) Qing Li et al. HEPATOLOGY
- Activated Fibroblast Program Orchestrates Tumor Initiation and Progression; Molecular Mechanisms and the Associated Therapeutic Strategies
- (2019) Go J. Yoshida et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- PKM2 is the target of proanthocyanidin B2 during the inhibition of hepatocellular carcinoma
- (2019) Jiao Feng et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- MicroRNA-196a/-196b regulate the progression of hepatocellular carcinoma through modulating the JAK/STAT pathway via targeting SOCS2
- (2019) Weihua Ren et al. Cell Death & Disease
- MiR-505 suppressed the growth of hepatocellular carcinoma cells via targeting IGF-1R
- (2019) Liang Ren et al. BIOSCIENCE REPORTS
- Glycochenodeoxycholate promotes hepatocellular carcinoma invasion and migration by AMPK/mTOR dependent autophagy activation
- (2019) Lu Gao et al. CANCER LETTERS
- Emerging roles of aerobic glycolysis in breast cancer
- (2019) Z. Wu et al. Clinical & Translational Oncology
- Alleviation of Hepatic Ischemia Reperfusion Injury by Oleanolic Acid Pretreating via Reducing HMGB1 Release and Inhibiting Apoptosis and Autophagy
- (2019) Wenwen Wang et al. MEDIATORS OF INFLAMMATION
- The combination of the glycolysis inhibitor 2-DG and sorafenib can be effective against sorafenib-tolerant persister cancer cells
- (2019) Li Wang et al. OncoTargets and Therapy
- 15-Deoxy-∆-12,14-Prostaglandin J2 (15d-PGJ2), an Endogenous Ligand of PPAR-γ: Function and Mechanism
- (2019) Jingjing Li et al. PPAR Research
- Quercetin shows anti‐tumor effect in hepatocellular carcinoma LM3 cells by abrogating JAK2/STAT3 signaling pathway
- (2019) Liwei Wu et al. Cancer Medicine
- A tumor agnostic therapeutic strategy for Hexokinase 1 Null/Hexokinase 2 positive cancers
- (2019) Shili Xu et al. CANCER RESEARCH
- miR-455-5p suppresses hepatocellular carcinoma cell growth and invasion via IGF-1R/AKT/GLUT1 pathway by targeting IGF-1R
- (2019) Yiren Hu et al. PATHOLOGY RESEARCH AND PRACTICE
- MiR-885-5p Negatively Regulates Warburg Effect by Silencing Hexokinase 2 in Liver Cancer
- (2019) Fei Xu et al. Molecular Therapy-Nucleic Acids
- STAT3 Mediates the Differential Effects of Oncostatin M and TNFα on RA Synovial Fibroblast and Endothelial Cell Function
- (2019) Megan M. Hanlon et al. Frontiers in Immunology
- Inhibition of GSK-3β activity suppresses HCC malignant phenotype by inhibiting glycolysis via activating AMPK/mTOR signaling
- (2019) Guoxu Fang et al. CANCER LETTERS
- Mitochondrial metabolic study guided by proteomics analysis in hepatocellular carcinoma cells surviving long-term incubation with the highest dose of sorafenib
- (2019) Jing Bai et al. Aging-US
- MFN1-dependent alteration of mitochondrial dynamics drives hepatocellular carcinoma metastasis by glucose metabolic reprogramming
- (2019) Ze Zhang et al. BRITISH JOURNAL OF CANCER
- miR-142-3p inhibits aerobic glycolysis and cell proliferation in hepatocellular carcinoma via targeting LDHA
- (2018) Shengni Hua et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- PKM1 Confers Metabolic Advantages and Promotes Cell-Autonomous Tumor Cell Growth
- (2018) Mami Morita et al. CANCER CELL
- PDSS2 deficiency induces hepatocarcinogenesis by decreasing mitochondrial respiration and reprogramming glucose metabolism
- (2018) Yan Li et al. CANCER RESEARCH
- Crosstalk between the Warburg effect, redox regulation and autophagy induction in tumourigenesis
- (2018) Mokgadi Violet Gwangwa et al. CELLULAR & MOLECULAR BIOLOGY LETTERS
- The potential utility of PFKFB3 as a therapeutic target
- (2018) Ramon Bartrons et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- PKM2, a potential target for regulating cancer
- (2018) Yu-huan Li et al. GENE
- Significance and mechanism of androgen receptor overexpression and androgen receptor/mechanistic target of rapamycin cross-talk in hepatocellular carcinoma
- (2018) Hong Zhang et al. HEPATOLOGY
- PFKFB3 is involved in breast cancer proliferation, migration, invasion and angiogenesis
- (2018) Fang Peng et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- lncRNA Ftx promotes aerobic glycolysis and tumor progression through the PPARγ pathway in hepatocellular carcinoma
- (2018) Xiao Li et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Exosomal microRNA-32-5p induces multidrug resistance in hepatocellular carcinoma via the PI3K/Akt pathway
- (2018) Xiao Fu et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Combinatorial treatment of Rhizoma Paridis saponins and sorafenib overcomes the intolerance of sorafenib
- (2018) Jingwen Yao et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Lenvatinib versus sorafenib in first-line treatment of patients with unresectable hepatocellular carcinoma: a randomised phase 3 non-inferiority trial
- (2018) Masatoshi Kudo et al. LANCET
- MicroRNA‑34a inhibits liver cancer cell growth by reprogramming glucose metabolism
- (2018) Hai‑Feng Zhang et al. Molecular Medicine Reports
- miR-139-5p inhibits aerobic glycolysis, cell proliferation, migration, and invasion in hepatocellular carcinoma via a reciprocal regulatory interaction with ETS1
- (2018) Shengni Hua et al. ONCOGENE
- A Randomized Phase II Open-Label Multi-Institution Study of the Combination of Bevacizumab and Erlotinib Compared to Sorafenib in the First-Line Treatment of Patients with Advanced Hepatocellular Carcinoma
- (2018) Melanie B. Thomas et al. ONCOLOGY
- miR-342-3p suppresses hepatocellular carcinoma proliferation through inhibition of IGF-1R-mediated Warburg effect
- (2018) Wenpeng Liu et al. OncoTargets and Therapy
- TCF7L2 positively regulates aerobic glycolysis via the EGLN2/HIF-1α axis and indicates prognosis in pancreatic cancer
- (2018) Jinfeng Xiang et al. Cell Death & Disease
- MiR-3662 suppresses hepatocellular carcinoma growth through inhibition of HIF-1α-mediated Warburg effect
- (2018) Zhiqiang Chen et al. Cell Death & Disease
- Inhibition of the PI3K/Akt signaling pathway reverses sorafenib‑derived chemo‑resistance in hepatocellular carcinoma
- (2018) Hao Zhang et al. Oncology Letters
- Hexokinase-2 depletion inhibits glycolysis and induces oxidative phosphorylation in hepatocellular carcinoma and sensitizes to metformin
- (2018) Dannielle DeWaal et al. Nature Communications
- Role of PKM2 in directing the metabolic fate of glucose in cancer: a potential therapeutic target
- (2018) Gustav van Niekerk et al. CELLULAR ONCOLOGY
- Oviductus ranae protein hydrolysate (ORPH) inhibits the growth, metastasis and glycolysis of HCC by targeting miR-491-5p/PKM2 axis
- (2018) Qiuran Xu et al. BIOMEDICINE & PHARMACOTHERAPY
- Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
- (2018) Freddie Bray et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Dauricine upregulates the chemosensitivity of hepatocellular carcinoma cells: Role of repressing glycolysis via miR-199a:HK2/PKM2 modulation
- (2018) Wei Li et al. FOOD AND CHEMICAL TOXICOLOGY
- Emerging roles of Myc in stem cell biology and novel tumor therapies
- (2018) Go J. Yoshida JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- LDH-A regulates the tumor microenvironment via HIF-signaling and modulates the immune response
- (2018) Inna Serganova et al. PLoS One
- Shikonin exerts antitumor activity by causing mitochondrial dysfunction in hepatocellular carcinoma through PKM2-AMPK-PGC1α signaling pathway
- (2018) Bing Liu et al. Biochemistry and Cell Biology
- Role of autophagy in tumorigenesis, metastasis, targeted therapy and drug resistance of hepatocellular carcinoma
- (2018) Fang Huang et al. WORLD JOURNAL OF GASTROENTEROLOGY
- CX-3543 Promotes Cell Apoptosis through Downregulation of CCAT1 in Colon Cancer Cells
- (2018) Yu-xia Yao et al. Biomed Research International
- Androgen receptor (AR)/miR-520f-3p/SOX9 signaling is involved in altering hepatocellular carcinoma (HCC) cell sensitivity to the Sorafenib therapy under hypoxia via increasing cancer stem cells phenotype
- (2018) Yao Xiao et al. CANCER LETTERS
- Gankyrin drives metabolic reprogramming to promote tumorigenesis, metastasis and drug resistance through activating β-catenin/c-Myc signaling in human hepatocellular carcinoma
- (2018) Ruiqi Liu et al. CANCER LETTERS
- Liver Cancer Cell of Origin, Molecular Class, and Effects on Patient Prognosis
- (2017) Daniela Sia et al. GASTROENTEROLOGY
- Clear cell hepatocellular carcinoma: origin, metabolic traits and fate of glycogenotic clear and ground glass cells
- (2017) Peter Bannasch et al. Hepatobiliary & Pancreatic Diseases International
- Taurine up-regulated gene 1 functions as a master regulator to coordinate glycolysis and metastasis in hepatocellular carcinoma
- (2017) Yang-Hsiang Lin et al. HEPATOLOGY
- By inhibiting PFKFB3, aspirin overcomes sorafenib resistance in hepatocellular carcinoma
- (2017) Sainan Li et al. INTERNATIONAL JOURNAL OF CANCER
- Chemotherapy for hepatocellular carcinoma: current status and future perspectives
- (2017) Masafumi Ikeda et al. JAPANESE JOURNAL OF CLINICAL ONCOLOGY
- Astragalin Reduces Hexokinase 2 through Increasing miR-125b to Inhibit the Proliferation of Hepatocellular Carcinoma Cells in Vitro and in Vivo
- (2017) Wei Li et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Therapeutic strategies of drug repositioning targeting autophagy to induce cancer cell death: from pathophysiology to treatment
- (2017) Go J. Yoshida Journal of Hematology & Oncology
- Metformin Promotes 2-Deoxy-2-[18F]Fluoro-D-Glucose Uptake in Hepatocellular Carcinoma Cells Through FoxO1-Mediated Downregulation of Glucose-6-Phosphatase
- (2017) Zhengjie Wang et al. MOLECULAR IMAGING AND BIOLOGY
- Promotion of glycolysis by HOTAIR through GLUT1 upregulation via mTOR signaling
- (2017) Shibo Wei et al. ONCOLOGY REPORTS
- Mutual Regulation of MiR-199a-5p and HIF-1α Modulates the Warburg Effect in Hepatocellular Carcinoma
- (2017) Binkui Li et al. Journal of Cancer
- Androgen Receptor Could Be a Potential Therapeutic Target in Patients with Advanced Hepatocellular Carcinoma
- (2017) Tatsuo Kanda et al. Cancers
- High expression of hexokinase domain containing 1 is associated with poor prognosis and aggressive phenotype in hepatocarcinoma
- (2016) Zijian Zhang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Functional characterization of AMP-activated protein kinase signaling in tumorigenesis
- (2016) Ji Cheng et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- The Warburg effect and drug resistance
- (2016) Bhaskar Bhattacharya et al. BRITISH JOURNAL OF PHARMACOLOGY
- PI3K/AKT/mTOR: role in breast cancer progression, drug resistance, and treatment
- (2016) Angel Guerrero-Zotano et al. CANCER AND METASTASIS REVIEWS
- p62/SQSTM1 by Binding to Vitamin D Receptor Inhibits Hepatic Stellate Cell Activity, Fibrosis, and Liver Cancer
- (2016) Angeles Duran et al. CANCER CELL
- The anti-angiogenic effect of dexamethasone in a murine hepatocellular carcinoma model by augmentation of gluconeogenesis pathway in malignant cells
- (2016) Fei Shang et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- SIRT2-Mediated Deacetylation and Tetramerization of Pyruvate Kinase Directs Glycolysis and Tumor Growth
- (2016) Seong-Hoon Park et al. CANCER RESEARCH
- Metabolic Alterations in Renal and Prostate Cancer
- (2016) Chiara Ciccarese et al. CURRENT DRUG METABOLISM
- Advanced Hepatocellular Cancer: the Current State of Future Research
- (2016) Louise C. Connell et al. CURRENT TREATMENT OPTIONS IN ONCOLOGY
- HKDC1 Is a Novel Hexokinase Involved in Whole-Body Glucose Use
- (2016) Anton E. Ludvik et al. ENDOCRINOLOGY
- Measuring relative utilization of aerobic glycolysis in breast cancer cells by positional isotopic discrimination
- (2016) Da-Qing Yang et al. FEBS LETTERS
- Nestin overexpression in hepatocellular carcinoma associates with epithelial-mesenchymal transition and chemoresistance
- (2016) Yan Zhang et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Emerging role of epithelial-mesenchymal transition in hepatic cancer
- (2016) Go J. Yoshida JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Targeting autophagy to sensitive glioma to temozolomide treatment
- (2016) Yuanliang Yan et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- PKM2 promotes tumor angiogenesis by regulating HIF-1α through NF-κB activation
- (2016) Ninel Azoitei et al. Molecular Cancer
- Sensitization of hepatocellular carcinoma cells to irradiation by miR-34a through targeting lactate dehydrogenase-A
- (2016) XIAOGANG LI et al. Molecular Medicine Reports
- The HK2 Dependent “Warburg Effect” and Mitochondrial Oxidative Phosphorylation in Cancer: Targets for Effective Therapy with 3-Bromopyruvate
- (2016) Paweł Lis et al. MOLECULES
- Glycolysis gene expression analysis and selective metabolic advantage in the clinical progression of colorectal cancer
- (2016) F Graziano et al. PHARMACOGENOMICS JOURNAL
- Reprogramming of glucose metabolism in hepatocellular carcinoma: Progress and prospects
- (2016) Run-Ze Shang et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Glucose metabolism in gastric cancer: The cutting-edge
- (2016) Lian-Wen Yuan WORLD JOURNAL OF GASTROENTEROLOGY
- microRNA-129-5p, a c-Myc negative target, affects hepatocellular carcinoma progression by blocking the Warburg effect
- (2016) Han Han et al. Journal of Molecular Cell Biology
- 2-Deoxyglucose and sorafenib synergistically suppress the proliferation and motility of hepatocellular carcinoma cells
- (2016) Minoru Tomizawa et al. Oncology Letters
- Fasting and cancer treatment in humans: A case series report
- (2016) Fernando M. Safdie et al. Aging-US
- PKM2 contributes to cancer metabolism
- (2015) Nicholas Wong et al. CANCER LETTERS
- Suppression of miR-199a maturation by HuR is crucial for hypoxia-induced glycolytic switch in hepatocellular carcinoma
- (2015) L.-F. Zhang et al. EMBO JOURNAL
- Aerobic glycolysis tunes YAP/TAZ transcriptional activity
- (2015) E. Enzo et al. EMBO JOURNAL
- MiR-199a-5p is negatively associated with malignancies and regulates glycolysis and lactate production by targeting hexokinase 2 in liver cancer
- (2015) Weijie Guo et al. HEPATOLOGY
- The Role of Autophagy in Hepatocellular Carcinoma
- (2015) Yoo Lee et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Metabolic reprogramming: the emerging concept and associated therapeutic strategies
- (2015) Go J. Yoshida JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Activation of the FGFR1 signalling pathway by the Epstein-Barr virus-encoded LMP1 promotes aerobic glycolysis and transformation of human nasopharyngeal epithelial cells
- (2015) Angela Kwok-Fung Lo et al. JOURNAL OF PATHOLOGY
- AMPK and PFKFB3 mediate glycolysis and survival in response to mitophagy during mitotic arrest
- (2015) Elena Doménech et al. NATURE CELL BIOLOGY
- MicroRNA-122 affects cell aggressiveness and apoptosis by targeting PKM2 in human hepatocellular carcinoma
- (2015) QIURAN XU et al. ONCOLOGY REPORTS
- l-cysteine reversibly inhibits glucose-induced biphasic insulin secretion and ATP production by inactivating PKM2
- (2015) Daiki Nakatsu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Transcriptional and Chromatin Regulation during Fasting – The Genomic Era
- (2015) Ido Goldstein et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- miR-125a inhibits the migration and invasion of liver cancer cells via suppression of the PI3K/AKT/mTOR signaling pathway
- (2015) HAO TANG et al. Oncology Letters
- PARP14 promotes the Warburg effect in hepatocellular carcinoma by inhibiting JNK1-dependent PKM2 phosphorylation and activation
- (2015) Valeria Iansante et al. Nature Communications
- Fasting induces anti-Warburg effect that increases respiration but reduces ATP-synthesis to promote apoptosis in colon cancer models
- (2015) Giovanna Bianchi et al. Oncotarget
- Metastasis-associated in colon cancer-1 is associated with poor prognosis in hepatocellular carcinoma, partly by promoting proliferation through enhanced glucose metabolism
- (2015) YAOQING LI et al. Molecular Medicine Reports
- Phosphofructokinase: A mediator of glycolytic flux in cancer progression
- (2014) Nada Al Hasawi et al. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
- Lupeol induces apoptosis and inhibits invasion in gallbladder carcinoma GBC-SD cells by suppression of EGFR/MMP-9 signaling pathway
- (2014) Yan Liu et al. CYTOTECHNOLOGY
- Involvement of androgen receptor and glucose-regulated protein 78kDa in human hepatocarcinogenesis
- (2014) Xia Jiang et al. EXPERIMENTAL CELL RESEARCH
- Regulation of Glucose Metabolism in Hepatocarcinogenesis by MicroRNAs
- (2014) Ryan K. Reyes et al. GENE EXPRESSION
- AMP-activated protein kinase: a key regulator of energy balance with many roles in human disease
- (2014) D. Grahame Hardie JOURNAL OF INTERNAL MEDICINE
- Overexpression of microRNA-125b sensitizes human hepatocellular carcinoma cells to 5-fluorouracil through inhibition of glycolysis by targeting hexokinase II
- (2014) JIAN-XIN JIANG et al. Molecular Medicine Reports
- PI3K and cancer: lessons, challenges and opportunities
- (2014) David A. Fruman et al. NATURE REVIEWS DRUG DISCOVERY
- Switching of Pyruvate Kinase Isoform L to M2 Promotes Metabolic Reprogramming in Hepatocarcinogenesis
- (2014) Carmen Chak-Lui Wong et al. PLoS One
- Mechanisms of regulation of PFKFB expression in pancreatic and gastric cancer cells
- (2014) Oleksandr H Minchenko WORLD JOURNAL OF GASTROENTEROLOGY
- 6-Phosphofructo-2-kinase (PFKFB3) promotes cell cycle progression and suppresses apoptosis via Cdk1-mediated phosphorylation of p27
- (2014) A Yalcin et al. Cell Death & Disease
- INPP4B-mediated tumor resistance is associated with modulation of glucose metabolism via hexokinase 2 regulation in laryngeal cancer cells
- (2013) Joong Won Min et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- p53 regulates glucose metabolism by miR-34a
- (2013) Hwa-Ryeon Kim et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- AMPK: A Target for Drugs and Natural Products With Effects on Both Diabetes and Cancer
- (2013) D. G. Hardie DIABETES
- 17β-Estradiol Activates Glucose Uptake via GLUT4 Translocation and PI3K/Akt Signaling Pathway in MCF-7 Cells
- (2013) Pablo Garrido et al. ENDOCRINOLOGY
- Aerobic glycolysis: a novel target in kidney cancer
- (2013) Brian Shuch et al. Expert Review of Anticancer Therapy
- Tissue metabolomics of hepatocellular carcinoma: Tumor energy metabolism and the role of transcriptomic classification
- (2013) Diren Beyoğlu et al. HEPATOLOGY
- Tat-activating regulatory DNA-binding protein regulates glycolysis in hepatocellular carcinoma by regulating the platelet isoform of phosphofructokinase through microRNA 520
- (2013) Yun-Yong Park et al. HEPATOLOGY
- Mitogenic and Oncogenic Stimulation of K433 Acetylation Promotes PKM2 Protein Kinase Activity and Nuclear Localization
- (2013) Lei Lv et al. MOLECULAR CELL
- Mitochondrial DNA alterations and mitochondrial dysfunction in the progression of hepatocellular carcinoma
- (2013) Chia-Chi Hsu WORLD JOURNAL OF GASTROENTEROLOGY
- Activating oxidative phosphorylation by a pyruvate dehydrogenase kinase inhibitor overcomes sorafenib resistance of hepatocellular carcinoma
- (2012) Y-C Shen et al. BRITISH JOURNAL OF CANCER
- Mitochondria-Targeted Drugs Synergize with 2-Deoxyglucose to Trigger Breast Cancer Cell Death
- (2012) G. Cheng et al. CANCER RESEARCH
- p70S6 Kinase Phosphorylates AMPK on Serine 491 to Mediate Leptin's Effect on Food Intake
- (2012) Yossi Dagon et al. Cell Metabolism
- AMPK Is a Negative Regulator of the Warburg Effect and Suppresses Tumor Growth In Vivo
- (2012) Brandon Faubert et al. Cell Metabolism
- MicroRNA-7 inhibits tumor growth and metastasis by targeting the phosphoinositide 3-kinase/Akt pathway in hepatocellular carcinoma
- (2012) YuXiang Fang et al. HEPATOLOGY
- Small molecule inhibition of 6-phosphofructo-2-kinase suppresses t cell activation
- (2012) Sucheta Telang et al. Journal of Translational Medicine
- ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect
- (2012) Weiwei Yang et al. NATURE CELL BIOLOGY
- Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis
- (2012) Dimitrios Anastasiou et al. Nature Chemical Biology
- AMPK: a nutrient and energy sensor that maintains energy homeostasis
- (2012) D. Grahame Hardie et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The Ancient Drug Salicylate Directly Activates AMP-Activated Protein Kinase
- (2012) S. A. Hawley et al. SCIENCE
- PPARγ contributes to PKM2 and HK2 expression in fatty liver
- (2012) Ganna Panasyuk et al. Nature Communications
- Pyruvate Kinase M2 Is a PHD3-Stimulated Coactivator for Hypoxia-Inducible Factor 1
- (2011) Weibo Luo et al. CELL
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Reduced survival of patients with hepatocellular carcinoma expressing hexokinase II
- (2011) Lei Gong et al. MEDICAL ONCOLOGY
- AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
- (2011) Joungmok Kim et al. NATURE CELL BIOLOGY
- Non-coding RNAs in human disease
- (2011) Manel Esteller NATURE REVIEWS GENETICS
- Enhancement of cytotoxic and pro-apoptotic effects of 2-aminophenoxazine-3-one on the rat hepatocellular carcinoma cell line dRLh-84, the human hepatocellular carcinoma cell line HepG2, and the rat normal hepatocellular cell line RLN-10 in combination with 2-deoxy-D-glucose
- (2011) Akio Tomoda ONCOLOGY REPORTS
- Fasting-induced intestinal apoptosis is mediated by inducible nitric oxide synthase and interferon-γ in rat
- (2010) Junta Ito et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Pyruvate kinase type M2: A key regulator of the metabolic budget system in tumor cells
- (2010) Sybille Mazurek INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Pyruvate promotes tumor angiogenesis through HIF-1-dependent PAI-1 expression
- (2010) Kim INTERNATIONAL JOURNAL OF ONCOLOGY
- The alternative splicing repressors hnRNP A1/A2 and PTB influence pyruvate kinase isoform expression and cell metabolism
- (2010) C. V. Clower et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy
- (2010) D. F. Egan et al. SCIENCE
- Regulatory crosstalk of the metabolic network
- (2010) Nana-Maria Grüning et al. TRENDS IN BIOCHEMICAL SCIENCES
- MYC-Induced Cancer Cell Energy Metabolism and Therapeutic Opportunities
- (2009) C. V. Dang et al. CLINICAL CANCER RESEARCH
- Regulation of glucose metabolism by 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatases in cancer
- (2009) Abdullah Yalcin et al. EXPERIMENTAL AND MOLECULAR PATHOLOGY
- Identification of androgen response elements in the enhancer I of hepatitis B virus: A mechanism for sex disparity in chronic hepatitis B
- (2009) Sheng-Han Wang et al. HEPATOLOGY
- HIF-1α Modulates Energy Metabolism in Cancer Cells by Inducing Over-Expression of Specific Glycolytic Isoforms
- (2009) Alvaro Marin-Hernandez et al. MINI-REVIEWS IN MEDICINAL CHEMISTRY
- Somatic mutations of mitochondrial genome in hepatocellular carcinoma
- (2009) Pen-Hui Yin et al. MITOCHONDRION
- c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism
- (2009) Ping Gao et al. NATURE
- Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
- (2009) M. G. Vander Heiden et al. SCIENCE
- Carrot and stick: HIF-α engages c-Myc in hypoxic adaptation
- (2008) L E Huang CELL DEATH AND DIFFERENTIATION
- The Biology of Cancer: Metabolic Reprogramming Fuels Cell Growth and Proliferation
- (2008) Ralph J. DeBerardinis et al. Cell Metabolism
- Androgen Receptor Is a New Potential Therapeutic Target for the Treatment of Hepatocellular Carcinoma
- (2008) Weng–Lung Ma et al. GASTROENTEROLOGY
- Sorafenib in Advanced Hepatocellular Carcinoma
- (2008) Josep M. Llovet et al. NEW ENGLAND JOURNAL OF MEDICINE
- Apigenin Inhibits the GLUT-1 Glucose Transporter and the Phosphoinositide 3-Kinase/Akt Pathway in Human Pancreatic Cancer Cells
- (2008) Laleh G. Melstrom et al. PANCREAS
- Hexokinase-2 bound to mitochondria: Cancer's stygian link to the “Warburg effect” and a pivotal target for effective therapy
- (2008) Saroj P. Mathupala et al. SEMINARS IN CANCER BIOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now