标题
Considerations for successful cancer immunotherapy in aged hosts
作者
关键词
-
出版物
CLINICAL AND EXPERIMENTAL IMMUNOLOGY
Volume 187, Issue 1, Pages 53-63
出版商
Wiley
发表日期
2016-10-07
DOI
10.1111/cei.12875
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Fasting-Mimicking Diet Reduces HO-1 to Promote T Cell-Mediated Tumor Cytotoxicity
- (2016) Stefano Di Biase et al. CANCER CELL
- Age-associated impairment of antitumor immunity in carcinoma-bearing mice and restoration by oral administration of Lentinula edodes mycelia extract
- (2016) Satoru Ishikawa et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Immune-Stimulatory Effects of Rapamycin Are Mediated by Stimulation of Antitumor T Cells
- (2016) V. Dao et al. CANCER RESEARCH
- Fine-Tuning Cancer Immunotherapy: Optimizing the Gut Microbiome
- (2016) J. M. Pitt et al. CANCER RESEARCH
- Microbiome and Anticancer Immunosurveillance
- (2016) Laurence Zitvogel et al. CELL
- sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance
- (2016) Amanpreet Kaur et al. NATURE
- Chronic mTOR inhibition in mice with rapamycin alters T, B, myeloid, and innate lymphoid cells and gut flora and prolongs life of immune-deficient mice
- (2015) Vincent Hurez et al. AGING CELL
- mTORC1 and mTORC2 selectively regulate CD8+ T cell differentiation
- (2015) Kristen N. Pollizzi et al. JOURNAL OF CLINICAL INVESTIGATION
- Myeloid-derived suppressor cells in the tumor microenvironment: expect the unexpected
- (2015) Douglas Marvel et al. JOURNAL OF CLINICAL INVESTIGATION
- Friends Not Foes: CTLA-4 Blockade and mTOR Inhibition Cooperate during CD8+T Cell Priming To Promote Memory Formation and Metabolic Readiness
- (2015) Virginia A. Pedicord et al. JOURNAL OF IMMUNOLOGY
- Commensal Bifidobacterium promotes antitumor immunity and facilitates anti-PD-L1 efficacy
- (2015) A. Sivan et al. SCIENCE
- Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota
- (2015) M. Vetizou et al. SCIENCE
- Adoptive cellular therapy: A race to the finish line
- (2015) Carl H. June et al. Science Translational Medicine
- IL-2/CD40-activated macrophages rescue age and tumor-induced T cell dysfunction in elderly mice
- (2014) C. Jackaman et al. AGE
- Lifespan-extending caloric restriction or mTOR inhibition impair adaptive immunity of old mice by distinct mechanisms
- (2014) Emily L. Goldberg et al. AGING CELL
- Caloric restriction maintains OX40 agonist-mediated tumor immunity and CD4 T cell priming during aging
- (2014) Michelle Farazi et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Intrinsic and Induced Regulation of the Age-Associated Onset of Spontaneous Experimental Autoimmune Encephalomyelitis
- (2014) H. Zhang et al. JOURNAL OF IMMUNOLOGY
- Cancer-Expanded Myeloid-Derived Suppressor Cells Induce Anergy of NK Cells through Membrane-Bound TGF- 1
- (2014) H. Li et al. JOURNAL OF IMMUNOLOGY
- Functional Regulatory T Cells Accumulate in Aged Hosts and Promote Chronic Infectious Disease Reactivation
- (2014) C. S. Lages et al. JOURNAL OF IMMUNOLOGY
- Subsets of Myeloid-Derived Suppressor Cells in Tumor-Bearing Mice
- (2014) J.-I. Youn et al. JOURNAL OF IMMUNOLOGY
- OX40-Enhanced Tumor Rejection and Effector T Cell Differentiation Decreases with Age
- (2014) C. E. Ruby et al. JOURNAL OF IMMUNOLOGY
- mTOR inhibition improves immune function in the elderly
- (2014) J. B. Mannick et al. Science Translational Medicine
- Impact of aging in cancer immunotherapy
- (2014) Myriam N Bouchlaka et al. OncoImmunology
- Targeting macrophages rescues age-related immune deficiencies in C57BL/6J geriatric mice
- (2013) Connie Jackaman et al. AGING CELL
- Aging is associated with increased regulatory T-cell function
- (2013) Sanjay K. Garg et al. AGING CELL
- Age-dependent changes in the expression of regulatory cell surface ligands in activated human T-cells
- (2013) David H Canaday et al. BMC IMMUNOLOGY
- eRapa Restores a Normal Life Span in a FAP Mouse Model
- (2013) P. Hasty et al. Cancer Prevention Research
- Are macrophages, myeloid derived suppressor cells and neutrophils mediators of local suppression in healthy and cancerous tissues in aging hosts?
- (2013) Connie Jackaman et al. EXPERIMENTAL GERONTOLOGY
- Aging predisposes to acute inflammatory induced pathology after tumor immunotherapy
- (2013) Myriam N. Bouchlaka et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Blood CD33(+)HLA-DR(−) myeloid-derived suppressor cells are increased with age and a history of cancer
- (2013) Chris P. Verschoor et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Commensal Bacteria Control Cancer Response to Therapy by Modulating the Tumor Microenvironment
- (2013) N. Iida et al. SCIENCE
- The Intestinal Microbiota Modulates the Anticancer Immune Effects of Cyclophosphamide
- (2013) S. Viaud et al. SCIENCE
- The Impact of Aging on Regulatory T-Cells
- (2013) Johannes Fessler et al. Frontiers in Immunology
- Human T Cell Aging and the Impact of Persistent Viral Infections
- (2013) T. Fülöp et al. Frontiers in Immunology
- Aged regulatory T cells protect from autoimmune inflammation despite reduced STAT3 activation and decreased constraint of IL-17 producing T cells
- (2012) Lishi Sun et al. AGING CELL
- Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate
- (2012) Patrick S. Ward et al. CANCER CELL
- Mitigating Age-Related Immune Dysfunction Heightens the Efficacy of Tumor Immunotherapy in Aged Mice
- (2012) V. Hurez et al. CANCER RESEARCH
- The Use of Agonistic Anti-CD40 Therapy in Treatments for Cancer
- (2012) Andrea Khong et al. INTERNATIONAL REVIEWS OF IMMUNOLOGY
- Immunotherapy earns its spot in the ranks of cancer therapy
- (2012) Drew Pardoll et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting
- (2012) Hirokazu Matsushita et al. NATURE
- Expression of tumour-specific antigens underlies cancer immunoediting
- (2012) Michel DuPage et al. NATURE
- Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer
- (2012) Julie R. Brahmer et al. NEW ENGLAND JOURNAL OF MEDICINE
- Safety, Activity, and Immune Correlates of Anti–PD-1 Antibody in Cancer
- (2012) Suzanne L. Topalian et al. NEW ENGLAND JOURNAL OF MEDICINE
- Colocalization of Inflammatory Response with B7-H1 Expression in Human Melanocytic Lesions Supports an Adaptive Resistance Mechanism of Immune Escape
- (2012) J. M. Taube et al. Science Translational Medicine
- Advanced Age Impairs Macrophage Polarization
- (2011) Shegufta Mahbub et al. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
- Cancer Immunoediting: Integrating Immunity's Roles in Cancer Suppression and Promotion
- (2011) R. D. Schreiber et al. SCIENCE
- Diminished Efficacy of Bacille Calmette-Guérin Among Elderly Patients with Nonmuscle Invasive Bladder Cancer
- (2011) David Margel et al. UROLOGY
- Partial restoration of T-cell function in aged mice by in vitro blockade of the PD-1/ PD-L1 pathway
- (2010) Celine S. Lages et al. AGING CELL
- Immunity, Inflammation, and Cancer
- (2010) Sergei I. Grivennikov et al. CELL
- Vessel abnormalization: another hallmark of cancer?Molecular mechanisms and therapeutic implications
- (2010) Katrien De Bock et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer
- (2010) A. E. Teschendorff et al. GENOME RESEARCH
- A Role for Immature Myeloid Cells in Immune Senescence
- (2010) E. Y. Enioutina et al. JOURNAL OF IMMUNOLOGY
- B7-H1 Expression on Old CD8+ T Cells Negatively Regulates the Activation of Immune Responses in Aged Animals
- (2010) N. Mirza et al. JOURNAL OF IMMUNOLOGY
- Cancer and Inflammation: Promise for Biologic Therapy
- (2010) Sandra Demaria et al. JOURNAL OF IMMUNOTHERAPY
- Transmission of donor melanoma by organ transplantation
- (2010) Dirk C Strauss et al. LANCET ONCOLOGY
- Genomic instability — an evolving hallmark of cancer
- (2010) Simona Negrini et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Improved Survival with Ipilimumab in Patients with Metastatic Melanoma
- (2010) F. Stephen Hodi et al. NEW ENGLAND JOURNAL OF MEDICINE
- The Effects of Aging on the Molecular and Cellular Composition of the Prostate Microenvironment
- (2010) Daniella Bianchi-Frias et al. PLoS One
- TGF-β1 Induces an Age-Dependent Inflammation of Nerve Ganglia and Fibroplasia in the Prostate Gland Stroma of a Novel Transgenic Mouse
- (2010) David A. Barron et al. PLoS One
- Obesity accelerates thymic aging
- (2009) H. Yang et al. BLOOD
- The effect of aging on OX40 agonist-mediated cancer immunotherapy
- (2009) Carl E. Ruby et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Use of CD40L immunoconjugates to overcome the defective immune response to vaccines for infections and cancer in the aged
- (2009) Yu Cheng Tang et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- FOXP3 Defines Regulatory T Cells in Human Tumor and Autoimmune Disease
- (2009) I. Kryczek et al. CANCER RESEARCH
- Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability
- (2009) F. Colotta et al. CARCINOGENESIS
- Age-associated up-regulation of a negative co-stimulatory receptor PD-1 in mouse CD4+ T cells
- (2009) Yukiko Shimada et al. EXPERIMENTAL GERONTOLOGY
- Myeloid-Derived Suppressor Cells: Linking Inflammation and Cancer
- (2009) S. Ostrand-Rosenberg et al. JOURNAL OF IMMUNOLOGY
- Advancing age leads to predominance of inhibitory receptor expressing CD4 T cells☆
- (2009) Rudragouda Channappanavar et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Aging and human CD4+ regulatory T cells
- (2009) Kyung-A. Hwang et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Aging in the lympho-hematopoietic stem cell compartment
- (2009) Hartmut Geiger et al. TRENDS IN IMMUNOLOGY
- Implications of Aging and Self-Tolerance on the Generation of Immune and Antitumor Immune Responses
- (2008) A. L. Dominguez et al. CANCER RESEARCH
- Regulatory T cells and treatment of cancer
- (2008) Tyler J Curiel CURRENT OPINION IN IMMUNOLOGY
- The inflammatory microenvironment of the aging prostate facilitates cellular proliferation and hypertrophy
- (2008) L.A. Begley et al. CYTOKINE
- Tumor-induced tolerance and immune suppression by myeloid derived suppressor cells
- (2008) Ilaria Marigo et al. IMMUNOLOGICAL REVIEWS
- Cancer-related inflammation
- (2008) Alberto Mantovani et al. NATURE
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